Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/RelE-RHH |
| Location | 1773..2269 | Replicon | plasmid pEcFELIX705.1 |
| Accession | NZ_CP101916 | ||
| Organism | Escherichia coli strain Evo1 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | NP443_RS22670 | Protein ID | WP_250694196.1 |
| Coordinates | 2042..2269 (+) | Length | 76 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | A0A829FT18 |
| Locus tag | NP443_RS22665 | Protein ID | WP_000079938.1 |
| Coordinates | 1773..2042 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NP443_RS22655 (NP443_22625) | 1..858 | + | 858 | WP_000130961.1 | incFII family plasmid replication initiator RepA | - |
| NP443_RS22660 (NP443_22630) | 1560..1700 | + | 141 | WP_160784086.1 | hypothetical protein | - |
| NP443_RS22665 (NP443_22635) | 1773..2042 | + | 270 | WP_000079938.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin |
| NP443_RS22670 (NP443_22640) | 2042..2269 | + | 228 | WP_250694196.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| NP443_RS22675 (NP443_22645) | 2587..2723 | + | 137 | Protein_4 | IS5/IS1182 family transposase | - |
| NP443_RS22680 (NP443_22650) | 2805..3501 | - | 697 | Protein_5 | IS1 family transposase | - |
| NP443_RS22685 (NP443_22655) | 3680..4648 | - | 969 | WP_256692679.1 | IS5 family transposase | - |
| NP443_RS22690 (NP443_22660) | 4689..4982 | - | 294 | WP_256692680.1 | biofilm development regulator YmgB/AriR family protein | - |
| NP443_RS22695 (NP443_22665) | 5298..5995 | + | 698 | WP_256692681.1 | IS1-like element IS1SD family transposase | - |
| NP443_RS22700 (NP443_22670) | 6063..6167 | - | 105 | Protein_9 | IS3 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | blaTEM-176 / aph(3')-Ia / ant(3'')-Ia / sul3 / lnu(F) / aac(3)-IId / tet(A) | - | 1..129083 | 129083 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|