MGE detailed information
MGE type: Conjugative plasmid MGE length: 106681 bp
Accession: NZ_CP101867 Location: 1..106681 Organism: Escherichia coli strain LP5-1 Replicon: plasmid pLP5-1-106kb
Accession: NZ_CP101867 Location: 1..106681 Organism: Escherichia coli strain LP5-1 Replicon: plasmid pLP5-1-106kb
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NPX81_RS22195 (1) | 1..858 | + | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| NPX81_RS22200 (1796) | 1796..2449 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NPX81_RS22205 (2542) | 2542..2799 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NPX81_RS22210 (2732) | 2732..3133 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NPX81_RS22215 (3382) | 3382..3797 | + | 416 | Protein_4 | IS1 family transposase | - |
| NPX81_RS22220 (3833) | 3833..4378 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NPX81_RS22225 (4444) | 4444..5152 | - | 709 | Protein_6 | IS6-like element IS26 family transposase | - |
| NPX81_RS22230 (5220) | 5220..5444 | - | 225 | Protein_7 | transposase | - |
| NPX81_RS22235 (5723) | 5723..6513 | - | 791 | Protein_8 | sulfonamide-resistant dihydropteroate synthase Sul3 | - |
| NPX81_RS22240 (7015) | 7015..7224 | - | 210 | WP_256633100.1 | GrpB family protein | - |
| NPX81_RS22245 (7262) | 7262..8125 | - | 864 | WP_054377175.1 | SDR family oxidoreductase | - |
| NPX81_RS22250 (8271) | 8271..9500 | - | 1230 | WP_032492336.1 | hypothetical protein | ARG |
| NPX81_RS22255 (9843) | 9843..10549 | - | 707 | Protein_12 | IS6 family transposase IS15DII | Transposase |
| NPX81_RS22260 (10700) | 10700..11515 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| NPX81_RS22265 (11705) | 11705..12410 | - | 706 | Protein_14 | IS6 family transposase | - |
| NPX81_RS22270 (12502) | 12502..13191 | + | 690 | Protein_15 | IS3 family transposase ISEhe3 | Transposase |
| NPX81_RS22275 (13255) | 13255..13470 | + | 216 | Protein_16 | serine/threonine protein kinase | - |
| NPX81_RS22280 (13590) | 13590..14315 | + | 726 | Protein_17 | site-specific integrase | - |
| NPX81_RS22285 (14600) | 14600..15574 | - | 975 | Protein_18 | RepB family plasmid replication initiator protein | - |
| NPX81_RS22290 (16325) | 16325..17288 | + | 964 | Protein_19 | hypothetical protein | - |
| NPX81_RS22295 (17444) | 17444..17602 | - | 159 | WP_228955855.1 | abortive infection family protein | - |
| NPX81_RS22300 (17750) | 17750..18446 | + | 697 | Protein_21 | IS1 family transposase | - |
| NPX81_RS22305 (18462) | 18462..18791 | + | 330 | Protein_22 | TOBE domain-containing protein | - |
| NPX81_RS22310 (18900) | 18900..19823 | - | 924 | Protein_23 | homocysteine S-methyltransferase | - |
| NPX81_RS22315 (19810) | 19810..21200 | - | 1391 | Protein_24 | S-methylmethionine permease | - |
| NPX81_RS22320 (21444) | 21444..22422 | + | 979 | Protein_25 | IS5 family transposase IS5D | Transposase |
| NPX81_RS22325 (22632) | 22632..22967 | + | 336 | WP_169329198.1 | type I deoxyribonuclease HsdR | - |
| NPX81_RS22330 (22917) | 22917..23330 | - | 414 | Protein_27 | IS3 family transposase ISLad1 | Transposase |
| NPX81_RS22335 (23335) | 23335..23613 | - | 279 | Protein_28 | pdcB | - |
| NPX81_RS22340 (23641) | 23641..23820 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| NPX81_RS22345 (23825) | 23825..24205 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| NPX81_RS22350 (24205) | 24205..24426 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| NPX81_RS22355 (24609) | 24609..26165 | + | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| NPX81_RS22360 (26162) | 26162..27445 | + | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| NPX81_RS22365 (27567) | 27567..30683 | + | 3117 | WP_039002890.1 | HsdR family type I site-specific deoxyribonuclease | - |
| NPX81_RS22370 (30897) | 30897..31594 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| NPX81_RS22375 (31731) | 31731..32624 | - | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| NPX81_RS22380 (32777) | 32777..34001 | - | 1225 | Protein_37 | IS3 family transposase | - |
| NPX81_RS22385 (34423) | 34423..34992 | - | 570 | WP_256633101.1 | hypothetical protein | - |
| NPX81_RS22390 (35460) | 35460..37589 | + | 2130 | Protein_39 | AAA family ATPase | - |
| NPX81_RS22395 (37751) | 37751..38166 | - | 416 | Protein_40 | type II toxin-antitoxin system VapC family toxin | - |
| NPX81_RS22400 (38163) | 38163..38394 | - | 232 | Protein_41 | type II toxin-antitoxin system VapB family antitoxin | - |
| NPX81_RS22405 (38961) | 38961..39266 | + | 306 | WP_256633102.1 | hypothetical protein | - |
| NPX81_RS22410 (39361) | 39361..39708 | + | 348 | WP_256633103.1 | hypothetical protein | - |
| NPX81_RS22415 (40176) | 40176..40460 | + | 285 | WP_256633104.1 | hypothetical protein | - |
| NPX81_RS22420 (40904) | 40904..41488 | + | 585 | WP_256633105.1 | hypothetical protein | - |
| NPX81_RS22425 (41631) | 41631..41804 | + | 174 | WP_256633106.1 | hypothetical protein | - |
| NPX81_RS22430 (42076) | 42076..43194 | + | 1119 | Protein_47 | DUF3800 domain-containing protein | - |
| NPX81_RS22435 (43214) | 43214..43498 | + | 285 | WP_256633107.1 | korC | - |
| NPX81_RS22440 (43921) | 43921..44070 | - | 150 | Protein_49 | IS30 family transposase | - |
| NPX81_RS22445 (44198) | 44198..44473 | + | 276 | WP_001331003.1 | IS3 family transposase IS629 | Transposase |
| NPX81_RS22450 (44473) | 44473..45357 | + | 885 | WP_256633108.1 | IS3 family transposase IS629 | Transposase |
| NPX81_RS22455 (45585) | 45585..45911 | + | 327 | WP_256633109.1 | hypothetical protein | - |
| NPX81_RS22460 (45939) | 45939..46220 | - | 282 | WP_256633110.1 | IS30 family transposase IS30D | Transposase |
| NPX81_RS22465 (46285) | 46285..47177 | + | 893 | Protein_54 | IS3 family transposase ISEhe3 | Transposase |
| NPX81_RS22470 (47279) | 47279..47560 | + | 282 | WP_000639434.1 | hypothetical protein | - |
| NPX81_RS22480 (48468) | 48468..49790 | + | 1323 | Protein_57 | reactive chlorine resistance oxidoreductase RclA | - |
| NPX81_RS22485 (49939) | 49939..50647 | - | 709 | Protein_58 | IS6 family transposase | - |
| NPX81_RS22490 (50638) | 50638..51144 | + | 507 | WP_001505085.1 | hypothetical protein | - |
| NPX81_RS22495 (51141) | 51141..51917 | + | 777 | Protein_60 | site-specific integrase | - |
| NPX81_RS22500 (52069) | 52069..52344 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| NPX81_RS22505 (52338) | 52338..52982 | - | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| NPX81_RS22510 (53204) | 53204..54175 | + | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| NPX81_RS22515 (54180) | 54180..54572 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| NPX81_RS22520 (54577) | 54577..55848 | - | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| NPX81_RS22525 (55848) | 55848..56285 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NPX81_RS22530 (56282) | 56282..56530 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| NPX81_RS22535 (56948) | 56948..57850 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| NPX81_RS22540 (57847) | 57847..58158 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| NPX81_RS22545 (58235) | 58235..58918 | + | 684 | WP_000086185.1 | DNA methylase | - |
| NPX81_RS22550 (58919) | 58919..59140 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| NPX81_RS22555 (59070) | 59070..59588 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| NPX81_RS22560 (59639) | 59639..60415 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| NPX81_RS22565 (60832) | 60832..61257 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| NPX81_RS22570 (61304) | 61304..61726 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| NPX81_RS22575 (61723) | 61723..61914 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| NPX81_RS22580 (62949) | 62949..63179 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| NPX81_RS22585 (63231) | 63231..64592 | + | 1362 | WP_230069265.1 | DUF3560 domain-containing protein | - |
| NPX81_RS22590 (64640) | 64640..65203 | + | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| NPX81_RS22595 (65355) | 65355..65582 | + | 228 | WP_071961421.1 | hypothetical protein | - |
| NPX81_RS22600 (65823) | 65823..66029 | + | 207 | WP_000275853.1 | hypothetical protein | - |
| NPX81_RS22605 (66055) | 66055..66594 | + | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| NPX81_RS22610 (66651) | 66651..66884 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| NPX81_RS22615 (66949) | 66949..68907 | + | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| NPX81_RS22620 (68962) | 68962..69396 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| NPX81_RS22625 (69393) | 69393..70155 | + | 763 | Protein_86 | plasmid SOS inhibition protein A | - |
| NPX81_RS22630 (70124) | 70124..70312 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (70124) | 70124..70348 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (70124) | 70124..70348 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (70124) | 70124..70348 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (70124) | 70124..70348 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| NPX81_RS22635 (70334) | 70334..70483 | + | 150 | Protein_88 | plasmid maintenance protein Mok | - |
| NPX81_RS22640 (70425) | 70425..70550 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NPX81_RS22645 (70770) | 70770..71000 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| NPX81_RS22650 (70998) | 70998..71171 | - | 174 | Protein_91 | hypothetical protein | - |
| NPX81_RS22655 (71241) | 71241..71447 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| NPX81_RS22660 (71472) | 71472..71759 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| NPX81_RS22665 (71881) | 71881..72702 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| NPX81_RS22670 (72999) | 72999..73601 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| NPX81_RS22675 (73922) | 73922..74305 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NPX81_RS22680 (74492) | 74492..75181 | + | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| NPX81_RS22685 (75274) | 75274..75675 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| NPX81_RS22690 (75708) | 75708..76070 | + | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| NPX81_RS22695 (76075) | 76075..76386 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NPX81_RS22700 (76408) | 76408..76974 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| NPX81_RS22705 (76961) | 76961..77689 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| NPX81_RS22710 (77689) | 77689..79116 | + | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NPX81_RS22715 (79106) | 79106..79693 | + | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NPX81_RS22720 (79680) | 79680..80000 | + | 321 | WP_001057285.1 | conjugal transfer protein TrbD | - |
| NPX81_RS22725 (79997) | 79997..80512 | + | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NPX81_RS22730 (80647) | 80647..80868 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| NPX81_RS22735 (81028) | 81028..83655 | + | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| NPX81_RS22740 (83652) | 83652..84038 | + | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| NPX81_RS22745 (84035) | 84035..84667 | + | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| NPX81_RS22750 (84664) | 84664..85656 | + | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| NPX81_RS22755 (85665) | 85665..86303 | + | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| NPX81_RS22760 (86300) | 86300..88108 | + | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| NPX81_RS22765 (88135) | 88135..88395 | + | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| NPX81_RS22770 (88388) | 88388..89131 | + | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| NPX81_RS22775 (89292) | 89292..89528 | + | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NPX81_RS22780 (89515) | 89515..90060 | + | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NPX81_RS22785 (89990) | 89990..90352 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| NPX81_RS22790 (90352) | 90352..91725 | + | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| NPX81_RS22795 (91722) | 91722..94544 | + | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NPX81_RS22800 (94559) | 94559..95062 | + | 504 | WP_000605510.1 | hypothetical protein | - |
| NPX81_RS22805 (95094) | 95094..95825 | + | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| NPX81_RS22810 (96078) | 96078..98267 | + | 2190 | WP_039002212.1 | type IV conjugative transfer system coupling protein TraD | - |
| NPX81_RS22815 (98267) | 98267..103537 | + | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| NPX81_RS22820 (103557) | 103557..104300 | + | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| NPX81_RS22825 (104355) | 104355..104915 | + | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| NPX81_RS22830 (105050) | 105050..105262 | + | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| - (105604) | 105604..105665 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (105604) | 105604..105665 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (105604) | 105604..105665 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (105604) | 105604..105665 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| NPX81_RS22835 (105709) | 105709..105858 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| NPX81_RS22840 (106126) | 106126..106383 | + | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| NPX81_RS22845 (106486) | 106486..106669 | + | 184 | Protein_130 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|