MGE detailed information
MGE type: Conjugative plasmid MGE length: 127578 bp
Accession: NZ_CP101212 Location: 1..127578 Organism: Escherichia coli strain EC21Z-147 Replicon: plasmid pEC21Z147-128K
Accession: NZ_CP101212 Location: 1..127578 Organism: Escherichia coli strain EC21Z-147 Replicon: plasmid pEC21Z147-128K
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NML26_RS26120 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| NML26_RS26125 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| NML26_RS26130 (2124) | 2124..2312 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| NML26_RS26135 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| NML26_RS26140 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| NML26_RS26145 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| NML26_RS26150 (7449) | 7449..7628 | - | 180 | Protein_6 | transposase | - |
| NML26_RS26155 (7767) | 7767..8966 | + | 1200 | Protein_7 | IS3 family transposase IS629 | Transposase |
| NML26_RS26160 (9114) | 9114..9439 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| NML26_RS26165 (9538) | 9538..11046 | - | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| NML26_RS26170 (11745) | 11745..12095 | + | 351 | Protein_10 | IS3 family transposase | - |
| NML26_RS26175 (12690) | 12690..13877 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| NML26_RS26180 (13874) | 13874..15814 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| NML26_RS26185 (15818) | 15818..17188 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| NML26_RS26190 (17662) | 17662..17856 | + | 195 | Protein_14 | IS200-IS605 family transposase IS200C | Transposase |
| NML26_RS26195 (17985) | 17985..18926 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| NML26_RS26200 (19161) | 19161..20550 | - | 1390 | Protein_16 | ISNCY family transposase ISKpn21 | Transposase |
| NML26_RS26205 (20860) | 20860..21009 | - | 150 | Protein_17 | IS3 family transposase IS2 | Transposase |
| NML26_RS26210 (21187) | 21187..22380 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| NML26_RS26215 (23136) | 23136..23840 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NML26_RS26220 (23997) | 23997..24785 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| NML26_RS26225 (24916) | 24916..25389 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| NML26_RS26230 (25547) | 25547..26560 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| NML26_RS26235 (26763) | 26763..27113 | + | 351 | WP_219365728.1 | DUF3330 domain-containing protein | - |
| NML26_RS26240 (27322) | 27322..28026 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NML26_RS26245 (28684) | 28684..29421 | - | 738 | Protein_25 | IS3 family transposase IS2 | Transposase |
| NML26_RS26250 (29474) | 29474..30636 | + | 1163 | WP_085947598.1 | IS3 family transposase ISEc17 | Transposase |
| NML26_RS26255 (30653) | 30653..31173 | - | 521 | Protein_27 | IS3 family transposase IS2 | Transposase |
| NML26_RS26260 (31798) | 31798..32091 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| NML26_RS26265 (32149) | 32149..32348 | - | 200 | Protein_29 | lysis protein | - |
| NML26_RS26270 (32902) | 32902..33926 | + | 1025 | Protein_30 | integrase core domain-containing protein | - |
| NML26_RS26275 (35237) | 35237..36352 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| NML26_RS26280 (36492) | 36492..40151 | + | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| NML26_RS26285 (40255) | 40255..41484 | + | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| NML26_RS26290 (41569) | 41569..42525 | + | 957 | WP_000271274.1 | Ferri-bacillibactin esterase BesA | VF |
| NML26_RS26295 (42570) | 42570..44747 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| NML26_RS26300 (45613) | 45613..46647 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| NML26_RS26310 (47802) | 47802..48203 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NML26_RS26315 (48136) | 48136..48393 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NML26_RS26320 (48486) | 48486..49139 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NML26_RS26325 (49851) | 49851..52838 | - | 2988 | WP_000124023.1 | Tn3 family transposase TnpA_TnEc1 | Transposase |
| NML26_RS26330 (53006) | 53006..53410 | + | 405 | Protein_42 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| NML26_RS26335 (53538) | 53538..54371 | - | 834 | Protein_43 | permease | - |
| NML26_RS26340 (54403) | 54403..55974 | - | 1572 | WP_106487386.1 | IS66 family transposase ISCro1 | Transposase |
| NML26_RS26345 (55994) | 55994..56341 | - | 348 | WP_000624618.1 | IS66 family transposase ISCro1 | Transposase |
| NML26_RS26350 (56341) | 56341..57018 | - | 678 | WP_072740705.1 | IS66 family transposase ISCro1 | Transposase |
| NML26_RS26355 (57073) | 57073..57378 | - | 306 | Protein_47 | permease | - |
| NML26_RS26360 (57484) | 57484..57807 | + | 324 | WP_001175593.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| NML26_RS26365 (57909) | 57909..58606 | + | 698 | WP_223367361.1 | IS1 family transposase IS1S | Transposase |
| NML26_RS26370 (59112) | 59112..60650 | - | 1539 | WP_000099202.1 | IS66 family transposase ISEc22 | Transposase |
| NML26_RS26375 (60699) | 60699..61046 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| NML26_RS26380 (61043) | 61043..61447 | - | 405 | WP_000839181.1 | IS66 family transposase ISEc22 | Transposase |
| NML26_RS26385 (61646) | 61646..62503 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| NML26_RS26390 (62496) | 62496..62978 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| NML26_RS26395 (62971) | 62971..63018 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| NML26_RS26400 (63009) | 63009..63260 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| NML26_RS26405 (63277) | 63277..63534 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| NML26_RS26410 (63818) | 63818..63967 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (64011) | 64011..64072 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64011) | 64011..64072 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64011) | 64011..64072 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64011) | 64011..64072 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| NML26_RS26415 (64328) | 64328..64402 | - | 75 | Protein_59 | endonuclease | - |
| NML26_RS26420 (64648) | 64648..64860 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| NML26_RS26425 (64996) | 64996..65556 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| NML26_RS26430 (65659) | 65659..66519 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| NML26_RS26435 (66578) | 66578..67324 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| NML26_RS26440 (67344) | 67344..72614 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| NML26_RS26445 (72696) | 72696..72923 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| NML26_RS26450 (72923) | 72923..73321 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NML26_RS26455 (73330) | 73330..75483 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| NML26_RS26460 (75736) | 75736..76446 | - | 711 | WP_230133085.1 | conjugal transfer complement resistance protein TraT | - |
| NML26_RS26465 (76499) | 76499..76996 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| NML26_RS26470 (77012) | 77012..79834 | - | 2823 | WP_254825079.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NML26_RS26475 (79831) | 79831..81204 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| NML26_RS26480 (81204) | 81204..81584 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| NML26_RS26485 (81571) | 81571..81912 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| NML26_RS26490 (81842) | 81842..82387 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NML26_RS26495 (82374) | 82374..82658 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NML26_RS26500 (82739) | 82739..83053 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| NML26_RS26505 (83055) | 83055..83402 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| NML26_RS26510 (83418) | 83418..84161 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| NML26_RS26515 (84154) | 84154..84411 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| NML26_RS26520 (84438) | 84438..86246 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| NML26_RS26525 (86243) | 86243..86881 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| NML26_RS26530 (86890) | 86890..87882 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| NML26_RS26535 (87879) | 87879..88511 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| NML26_RS26540 (88508) | 88508..88894 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| NML26_RS26545 (88891) | 88891..91518 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| NML26_RS26550 (91678) | 91678..91899 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| NML26_RS26555 (92034) | 92034..92549 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NML26_RS26560 (92546) | 92546..92797 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| NML26_RS26565 (92809) | 92809..93006 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| NML26_RS26570 (92993) | 92993..93583 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NML26_RS26575 (93573) | 93573..95000 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NML26_RS26580 (95000) | 95000..95728 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| NML26_RS26585 (95715) | 95715..96281 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| NML26_RS26590 (96303) | 96303..96614 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NML26_RS26595 (96629) | 96629..96994 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| NML26_RS26600 (97027) | 97027..97428 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| NML26_RS26605 (97521) | 97521..98210 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| NML26_RS26610 (98397) | 98397..98780 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NML26_RS26615 (99101) | 99101..99703 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| NML26_RS26620 (100000) | 100000..100821 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| NML26_RS26625 (100939) | 100939..101226 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| NML26_RS26630 (101251) | 101251..101457 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| NML26_RS26635 (101527) | 101527..101699 | + | 173 | Protein_103 | hypothetical protein | - |
| NML26_RS26640 (101697) | 101697..101927 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| NML26_RS26645 (102147) | 102147..102272 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NML26_RS26650 (102214) | 102214..102363 | - | 150 | Protein_106 | plasmid maintenance protein Mok | - |
| - (102349) | 102349..102573 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (102349) | 102349..102573 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (102349) | 102349..102573 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (102349) | 102349..102573 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| NML26_RS26655 (102385) | 102385..102573 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| NML26_RS26660 (102542) | 102542..103304 | - | 763 | Protein_108 | plasmid SOS inhibition protein A | - |
| NML26_RS26665 (103301) | 103301..103735 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| NML26_RS26670 (103790) | 103790..103987 | - | 198 | Protein_110 | hypothetical protein | - |
| NML26_RS26675 (104015) | 104015..104248 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| NML26_RS26680 (104316) | 104316..104855 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| NML26_RS26685 (104881) | 104881..105087 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| NML26_RS26690 (105157) | 105157..105237 | + | 81 | Protein_114 | hypothetical protein | - |
| NML26_RS26695 (105420) | 105420..105589 | - | 170 | Protein_115 | hypothetical protein | - |
| NML26_RS26700 (106226) | 106226..107197 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NML26_RS26705 (107197) | 107197..108363 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| NML26_RS26715 (109845) | 109845..112046 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| NML26_RS26720 (112072) | 112072..113405 | - | 1334 | Protein_120 | L-lysine N6-monooxygenase | VF |
| NML26_RS26725 (113402) | 113402..115144 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| NML26_RS26730 (115144) | 115144..116091 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| NML26_RS26735 (116092) | 116092..117816 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| NML26_RS26740 (117952) | 117952..119145 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| NML26_RS26745 (119525) | 119525..119905 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| NML26_RS26750 (120246) | 120246..120659 | - | 414 | Protein_126 | phosphopyruvate hydratase | - |
| NML26_RS26755 (120657) | 120657..120914 | + | 258 | Protein_127 | transposase | - |
| NML26_RS26760 (121148) | 121148..122005 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| NML26_RS26765 (122002) | 122002..122859 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| NML26_RS26770 (122856) | 122856..123683 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| NML26_RS26775 (123683) | 123683..124597 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| NML26_RS26780 (124953) | 124953..125650 | + | 698 | WP_094096600.1 | IS1 family transposase IS1S | Transposase |
| NML26_RS26785 (125830) | 125830..126343 | - | 514 | Protein_133 | DUF4113 domain-containing protein | - |
| NML26_RS26790 (126404) | 126404..126508 | - | 105 | Protein_134 | AAA family ATPase | - |
| NML26_RS26795 (126510) | 126510..126833 | - | 324 | Protein_135 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|