MGE detailed information
MGE type: Conjugative plasmid MGE length: 102954 bp
Accession: NZ_CP097011 Location: 1..102954 Organism: Enterococcus faecalis strain AT48 Replicon: plasmid pAT48-a
Accession: NZ_CP097011 Location: 1..102954 Organism: Enterococcus faecalis strain AT48 Replicon: plasmid pAT48-a
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M2921_RS13070 (M2921_13075) | 1..1011 | + | 1011 | WP_002367743.1 | replication initiator protein A | - |
| M2921_RS13075 (M2921_13080) | 1142..1810 | + | 669 | WP_002362416.1 | type II CAAX endopeptidase family protein | - |
| M2921_RS13080 (M2921_13085) | 1853..3479 | + | 1627 | Protein_2 | peptide ABC transporter substrate-binding protein | - |
| M2921_RS14225 | 3657..3779 | + | 123 | WP_002415665.1 | hypothetical protein | - |
| M2921_RS13085 (M2921_13090) | 3779..4336 | + | 558 | WP_002362413.1 | hypothetical protein | - |
| M2921_RS13090 (M2921_13095) | 4257..5519 | - | 1263 | WP_000119405.1 | hypothetical protein | Relaxase |
| M2921_RS13095 (M2921_13100) | 5809..6456 | - | 648 | WP_002415230.1 | Chloramphenicol acetyltransferase | ARG |
| M2921_RS13100 (M2921_13105) | 6591..6902 | - | 312 | Protein_7 | replication initiation protein | - |
| M2921_RS13105 (M2921_13110) | 7498..8874 | - | 1377 | WP_001574277.1 | tetracycline efflux MFS transporter Tet(L) | ARG |
| M2921_RS13110 (M2921_13115) | 9068..10987 | - | 1920 | WP_001574275.1 | tetracycline resistance ribosomal protection protein Tet(M) | VF |
| M2921_RS13115 (M2921_13120) | 11003..11119 | - | 117 | WP_001791010.1 | tetracycline resistance determinant leader peptide | - |
| M2921_RS13120 (M2921_13125) | 11364..12296 | - | 933 | WP_001224319.1 | conjugal transfer protein | - |
| M2921_RS13125 (M2921_13130) | 12293..13294 | - | 1002 | WP_033918023.1 | hypothetical protein | VF |
| M2921_RS13130 (M2921_13135) | 13291..15468 | - | 2178 | WP_001574271.1 | YtxH domain-containing protein | - |
| M2921_RS13135 (M2921_13140) | 15471..17918 | - | 2448 | WP_000331160.1 | ATP-binding protein | - |
| M2921_RS13140 (M2921_13145) | 17902..18294 | - | 393 | WP_000723888.1 | conjugal transfer protein | - |
| M2921_RS13145 (M2921_13150) | 18383..18880 | - | 498 | WP_000342539.1 | antirestriction protein ArdA | - |
| M2921_RS13150 (M2921_13155) | 18997..19218 | - | 222 | WP_001009056.1 | hypothetical protein | - |
| M2921_RS13155 (M2921_13160) | 19261..20466 | - | 1206 | WP_033918024.1 | hypothetical protein | Relaxase |
| M2921_RS13160 (M2921_13165) | 20489..20641 | - | 153 | WP_000879507.1 | - | oriT |
| M2921_RS13165 (M2921_13170) | 20644..22029 | - | 1386 | WP_000813488.1 | FtsK/SpoIIIE domain-containing protein | - |
| M2921_RS13170 (M2921_13175) | 22058..22444 | - | 387 | WP_000985015.1 | YdcP family protein | - |
| M2921_RS13175 (M2921_13180) | 22460..22774 | - | 315 | WP_000420682.1 | YdcP family protein | - |
| M2921_RS13180 (M2921_13185) | 23116..23301 | + | 186 | Protein_23 | type IV secretory system conjugative DNA transfer family protein | - |
| M2921_RS13185 (M2921_13190) | 23351..25510 | + | 2160 | WP_002362410.1 | ArdC-like ssDNA-binding domain-containing protein | - |
| M2921_RS13190 (M2921_13195) | 25543..25815 | + | 273 | WP_002362409.1 | LtrD | - |
| M2921_RS13195 (M2921_13200) | 26061..26417 | + | 357 | WP_002362408.1 | hypothetical protein | Relaxase |
| M2921_RS13200 (M2921_13205) | 26418..28103 | + | 1686 | WP_033918025.1 | hypothetical protein | Relaxase |
| M2921_RS13205 (M2921_13210) | 28136..28486 | + | 351 | WP_002367698.1 | hypothetical protein | - |
| M2921_RS13210 (M2921_13215) | 29003..29626 | - | 624 | Protein_29 | PcfJ domain-containing protein | - |
| M2921_RS13215 (M2921_13220) | 29707..30387 | + | 681 | WP_162301543.1 | IS6 family transposase IS1216E | Transposase |
| M2921_RS13220 (M2921_13225) | 30450..30629 | - | 180 | WP_002325573.1 | DUF2933 domain-containing protein | - |
| M2921_RS13225 (M2921_13230) | 30632..30856 | - | 225 | WP_002405073.1 | DUF2933 domain-containing protein | - |
| M2921_RS13230 (M2921_13235) | 30840..31643 | - | 804 | WP_010821298.1 | prolipoprotein diacylglyceryl transferase | - |
| M2921_RS13235 (M2921_13240) | 31800..32414 | + | 615 | WP_002405071.1 | TIGR01906 family membrane protein | - |
| M2921_RS13240 (M2921_13245) | 32430..32795 | + | 366 | WP_002405070.1 | BlaI/MecI/CopY family transcriptional regulator | - |
| M2921_RS13245 (M2921_13250) | 32779..33210 | + | 432 | WP_002405069.1 | cation transporter | - |
| M2921_RS13250 (M2921_13255) | 33221..34807 | + | 1587 | WP_002405068.1 | multicopper oxidase domain-containing protein | - |
| M2921_RS13255 (M2921_13260) | 34835..35515 | + | 681 | WP_002294790.1 | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | VF |
| M2921_RS13260 (M2921_13265) | 35515..36909 | + | 1395 | WP_002294791.1 | HAMP domain-containing sensor histidine kinase | - |
| M2921_RS13265 (M2921_13270) | 36924..37130 | + | 207 | WP_002307659.1 | hypothetical protein | - |
| M2921_RS13270 (M2921_13275) | 37151..37747 | + | 597 | WP_002316691.1 | YdhK family protein | - |
| M2921_RS13275 (M2921_13280) | 37945..39246 | - | 1302 | Protein_42 | ISL3 family transposase IS1476 | Transposase |
| M2921_RS13280 (M2921_13285) | 39526..39870 | - | 345 | Protein_43 | ATPase P | - |
| M2921_RS13285 (M2921_13290) | 39945..40625 | + | 681 | Protein_44 | IS6 family transposase IS1297 | Transposase |
| M2921_RS13290 (M2921_13295) | 40797..41252 | + | 456 | WP_002405064.1 | copper-responsive transcriptional repressor TcrY | - |
| M2921_RS13295 (M2921_13300) | 41265..43729 | + | 2465 | Protein_46 | heavy metal translocating P-type ATPase | - |
| M2921_RS13300 (M2921_13305) | 43814..44020 | + | 207 | WP_002335389.1 | copper chaperone TcrZ | - |
| M2921_RS13305 (M2921_13310) | 44159..46291 | + | 2133 | WP_002346660.1 | copper-translocating P-type ATPase TcrB | - |
| M2921_RS13310 (M2921_13315) | 46423..47043 | + | 621 | WP_002294569.1 | adenylate kinase | - |
| M2921_RS13315 (M2921_13320) | 47115..47960 | + | 846 | Protein_50 | prolipoprotein diacylglyceryl transferase | - |
| M2921_RS13320 (M2921_13325) | 47973..48155 | + | 183 | WP_002405058.1 | hypothetical protein | - |
| M2921_RS13325 (M2921_13330) | 48334..48948 | + | 615 | WP_033918028.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| M2921_RS13330 (M2921_13335) | 49372..50361 | + | 990 | WP_002337512.1 | IS30 family transposase ISSau1 | Transposase |
| M2921_RS13335 (M2921_13340) | 50725..51726 | - | 1002 | WP_002344895.1 | DUF4062 domain-containing protein | - |
| M2921_RS13340 (M2921_13345) | 51885..52151 | - | 267 | WP_002344896.1 | helix-turn-helix transcriptional regulator | - |
| M2921_RS13345 (M2921_13350) | 52141..52497 | - | 357 | WP_002344897.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| M2921_RS13350 (M2921_13355) | 52632..53312 | + | 681 | WP_202583918.1 | IS6 family transposase IS1216E | Transposase |
| M2921_RS13355 (M2921_13360) | 53524..56673 | - | 3150 | WP_033918030.1 | HsdR family type I site-specific deoxyribonuclease | - |
| M2921_RS13360 (M2921_13365) | 56687..57928 | - | 1242 | WP_033918031.1 | restriction endonuclease subunit S | - |
| M2921_RS13365 (M2921_13370) | 57918..59513 | - | 1596 | WP_033918032.1 | type I restriction-modification system subunit M | - |
| M2921_RS13370 (M2921_13375) | 60056..60520 | + | 465 | WP_002405180.1 | ISL3 family transposase ISEfa5 | Transposase |
| M2921_RS13375 (M2921_13380) | 60698..61300 | - | 603 | WP_002405179.1 | hypothetical protein | - |
| M2921_RS13380 (M2921_13385) | 61331..63106 | - | 1776 | WP_033918033.1 | DUF262 domain-containing protein | - |
| M2921_RS13385 (M2921_13390) | 63322..64448 | + | 1127 | WP_104885698.1 | IS3 family transposase ISBce13 | Transposase |
| M2921_RS13390 (M2921_13395) | 64630..65325 | - | 696 | WP_002405176.1 | Fic family protein | - |
| M2921_RS13395 (M2921_13400) | 65374..65973 | - | 600 | WP_002405175.1 | Tyrosine recombinase XerC | VF |
| M2921_RS13405 (M2921_13410) | 67699..68301 | - | 603 | WP_002362434.1 | Fic family protein | - |
| M2921_RS13410 (M2921_13415) | 68566..69504 | - | 939 | WP_002362433.1 | hypothetical protein | - |
| M2921_RS13415 (M2921_13420) | 69616..69957 | - | 342 | WP_002362432.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| M2921_RS13420 (M2921_13425) | 69957..70187 | - | 231 | WP_002362431.1 | hypothetical protein | Antitoxin Detail |
| M2921_RS13425 (M2921_13430) | 70391..71011 | + | 621 | WP_002367784.1 | Tn3 family transposase TnpR_ISAli20 | Transposase |
| M2921_RS13430 (M2921_13435) | 71001..71315 | + | 315 | WP_002367785.1 | hypothetical protein | - |
| M2921_RS13435 (M2921_13440) | 71309..71515 | + | 207 | WP_002367786.1 | hypothetical protein | - |
| M2921_RS13440 (M2921_13445) | 71675..71869 | + | 195 | WP_002367787.1 | hypothetical protein | - |
| M2921_RS13445 (M2921_13450) | 71881..72072 | + | 192 | WP_002367788.1 | hypothetical protein | - |
| M2921_RS13450 (M2921_13455) | 72242..72457 | + | 216 | WP_002367791.1 | leucocin A/sakacin P family class II bacteriocin | - |
| M2921_RS13455 (M2921_13460) | 72458..72799 | + | 342 | WP_002367792.1 | bacteriocin immunity protein | - |
| M2921_RS13460 (M2921_13465) | 73215..73733 | + | 519 | WP_002367793.1 | hypothetical protein | - |
| M2921_RS13465 (M2921_13470) | 73681..73896 | + | 216 | WP_002415356.1 | hypothetical protein | - |
| M2921_RS13470 (M2921_13475) | 73988..74074 | + | 87 | WP_012881081.1 | type I toxin-antitoxin system Fst family toxin | - |
| M2921_RS13475 (M2921_13480) | 74331..74627 | + | 297 | WP_002367795.1 | hypothetical protein | - |
| M2921_RS13480 (M2921_13485) | 74762..75394 | + | 633 | WP_002367796.1 | AbiV family abortive infection protein | - |
| M2921_RS13485 (M2921_13490) | 76223..76960 | - | 738 | WP_001038795.1 | rRNA adenine N-6-methyltransferase | ARG |
| M2921_RS13490 (M2921_13495) | 77085..77168 | - | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| M2921_RS14230 | 77217..77300 | - | 84 | Protein_86 | MLS leader peptide | - |
| M2921_RS13495 (M2921_13500) | 77710..78504 | - | 795 | WP_001096887.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| M2921_RS13500 (M2921_13505) | 78597..79139 | - | 543 | WP_000627290.1 | streptothricin N-acetyltransferase Sat4 | - |
| M2921_RS13505 (M2921_13510) | 79136..80044 | - | 909 | WP_001255866.1 | Aminoglycoside 6-adenylyltransferase | ARG |
| M2921_RS13510 (M2921_13515) | 80077..80811 | - | 735 | WP_000662263.1 | class I SAM-dependent methyltransferase | - |
| M2921_RS13515 (M2921_13520) | 80792..81661 | - | 870 | WP_078126936.1 | nucleotidyltransferase domain-containing protein | Toxin Detail |
| M2921_RS13520 (M2921_13525) | 81676..81900 | - | 225 | WP_002303393.1 | helix-turn-helix transcriptional regulator | Antitoxin Detail |
| M2921_RS13525 (M2921_13530) | 82043..82864 | - | 822 | Protein_93 | recombinase zinc beta ribbon domain-containing protein | - |
| M2921_RS13530 (M2921_13535) | 83552..84355 | - | 804 | WP_002294514.1 | hypothetical protein | ARG |
| M2921_RS13535 (M2921_13540) | 84409..85894 | - | 1486 | Protein_95 | putative ABC transporter ATP-binding protein YheS | ARG |
| M2921_RS13540 (M2921_13545) | 86337..86900 | - | 564 | Protein_96 | recombinase zinc beta ribbon domain-containing protein | - |
| M2921_RS13545 (M2921_13550) | 86983..87441 | + | 459 | WP_002325145.1 | hypothetical protein | - |
| M2921_RS13550 (M2921_13555) | 87492..87743 | - | 252 | WP_002294510.1 | hypothetical protein | - |
| M2921_RS13555 (M2921_13560) | 87961..88770 | - | 810 | WP_002294509.1 | ANT(9) family aminoglycoside nucleotidyltransferase Spw | - |
| M2921_RS13560 (M2921_13565) | 88902..89429 | - | 528 | WP_002294507.1 | phosphoribosyltransferase family protein | - |
| M2921_RS13565 (M2921_13570) | 89473..90225 | - | 753 | Protein_101 | Aminoglycoside 6-adenylyltransferase | ARG |
| M2921_RS13570 (M2921_13575) | 90395..91834 | - | 1440 | WP_001028144.1 | Bifunctional AAC/APH | ARG |
| M2921_RS13575 (M2921_13580) | 91835..92227 | - | 393 | WP_000393259.1 | GNAT family N-acetyltransferase | - |
| M2921_RS13580 (M2921_13585) | 92246..92356 | - | 111 | Protein_104 | aminoglycoside 6-adenylyltransferase | - |
| M2921_RS13585 (M2921_13590) | 92375..92491 | - | 117 | Protein_105 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
| M2921_RS13590 (M2921_13595) | 92661..93398 | - | 738 | WP_001038795.1 | rRNA adenine N-6-methyltransferase | ARG |
| M2921_RS13595 (M2921_13600) | 93523..93606 | - | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| M2921_RS13600 (M2921_13605) | 93729..93896 | - | 168 | Protein_108 | peptide-binding protein | - |
| M2921_RS13605 (M2921_13610) | 94030..94656 | - | 627 | Protein_109 | DNA topoisomerase | - |
| M2921_RS13610 (M2921_13615) | 94732..95412 | + | 681 | WP_010710189.1 | IS6 family transposase IS1216E | Transposase |
| M2921_RS13615 (M2921_13620) | 95446..95952 | - | 507 | WP_002415429.1 | IS1595 family transposase ISSsu9 | ARG |
| M2921_RS13620 (M2921_13625) | 96249..96566 | - | 318 | WP_002326830.1 | hypothetical protein | - |
| M2921_RS13625 (M2921_13630) | 97006..97869 | - | 864 | WP_002332783.1 | zeta toxin family protein | Toxin Detail |
| M2921_RS13630 (M2921_13635) | 97871..98143 | - | 273 | WP_002326825.1 | antitoxin | Antitoxin Detail |
| M2921_RS13635 (M2921_13640) | 98161..98376 | - | 216 | WP_001835296.1 | peptide-binding protein | - |
| M2921_RS13640 (M2921_13645) | 98468..99364 | - | 897 | WP_002326827.1 | ParA family protein | - |
| M2921_RS13645 (M2921_13650) | 99467..99727 | - | 261 | Protein_117 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
| M2921_RS13650 (M2921_13655) | 99897..100634 | - | 738 | WP_001038795.1 | rRNA adenine N-6-methyltransferase | ARG |
| M2921_RS13655 (M2921_13660) | 100759..100842 | - | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| M2921_RS14235 | 100891..100974 | - | 84 | Protein_120 | MLS leader peptide | - |
| M2921_RS13660 (M2921_13665) | 101274..101645 | - | 372 | WP_002358205.1 | hypothetical protein | - |
| M2921_RS13665 (M2921_13670) | 101638..102483 | - | 846 | WP_000239313.1 | AAA family ATPase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|