MGE detailed information
MGE type: Conjugative plasmid MGE length: 117950 bp
Accession: NZ_CP095519 Location: 1..117950 Organism: Escherichia coli strain GN02350 Replicon: plasmid p2350-1
Accession: NZ_CP095519 Location: 1..117950 Organism: Escherichia coli strain GN02350 Replicon: plasmid p2350-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MW405_RS24920 () | 1..191 | + | 191 | Protein_0 | conjugal transfer protein TraH | - |
| MW405_RS24925 () | 188..3007 | + | 2820 | WP_001537571.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| MW405_RS24930 () | 3026..3523 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| MW405_RS24935 () | 3555..4286 | + | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| MW405_RS24940 () | 4489..5226 | + | 738 | WP_000199901.1 | hypothetical protein | - |
| MW405_RS24945 () | 5277..7484 | + | 2208 | WP_021513392.1 | type IV conjugative transfer system coupling protein TraD | - |
| MW405_RS24950 () | 7484..12754 | + | 5271 | WP_001545323.1 | Multifunctional conjugation protein TraI | Relaxase |
| MW405_RS24955 () | 12774..13520 | + | 747 | WP_000205709.1 | conjugal transfer pilus acetylase TraX | - |
| MW405_RS24960 () | 13575..14132 | + | 558 | WP_000139329.1 | fertility inhibition protein FinO | - |
| MW405_RS24965 () | 14284..14487 | + | 204 | WP_001336517.1 | hypothetical protein | - |
| MW405_RS24970 () | 15240..15701 | + | 462 | WP_000760080.1 | thermonuclease family protein | - |
| MW405_RS24975 () | 15804..16187 | + | 384 | WP_001109264.1 | hypothetical protein | - |
| MW405_RS24980 () | 16340..16777 | + | 438 | WP_000872609.1 | hypothetical protein | - |
| - () | 16872..16928 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 16872..16928 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 16872..16928 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| - () | 16872..16928 | - | 57 | NuclAT_1 | - | Antitoxin Detail |
| MW405_RS24985 () | 16976..17125 | + | 150 | WP_001336447.1 | Hok/Gef family protein | Toxin Detail |
| MW405_RS24990 () | 17410..17667 | + | 258 | WP_000084404.1 | replication regulatory protein RepA | - |
| MW405_RS24995 () | 17901..17975 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| MW405_RS25000 () | 17968..18825 | + | 858 | WP_001537577.1 | incFII family plasmid replication initiator RepA | - |
| MW405_RS25005 () | 19526..19666 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| MW405_RS25010 () | 19764..20417 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| MW405_RS25015 () | 20510..20767 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| MW405_RS25020 () | 20700..21101 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| MW405_RS25025 () | 21386..22696 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| MW405_RS25030 () | 22725..23422 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| MW405_RS25035 () | 23529..23873 | - | 345 | Protein_23 | MerR family DNA-binding protein | - |
| MW405_RS25040 () | 23875..24159 | - | 285 | Protein_24 | recombinase family protein | - |
| MW405_RS25045 () | 24290..24640 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| MW405_RS25050 () | 24843..25856 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| MW405_RS25055 () | 26005..26843 | + | 839 | Protein_27 | Streptomycin 3''-adenylyltransferase | ARG |
| MW405_RS25060 () | 26960..27307 | + | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| MW405_RS25065 () | 27301..28140 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| MW405_RS25070 () | 28268..28768 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| MW405_RS25075 () | 28944..29726 | - | 783 | WP_001163403.1 | IS21 family transposase IS1326 | Transposase |
| MW405_RS25080 () | 29716..30420 | - | 705 | Protein_32 | IS21 family transposase IS1326 | Transposase |
| MW405_RS25085 () | 30473..31177 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MW405_RS25090 () | 31238..32119 | + | 882 | Protein_34 | oligosaccharide MFS transporter | - |
| MW405_RS25095 () | 32150..33238 | - | 1089 | WP_001620097.1 | AAA family ATPase | - |
| MW405_RS25100 () | 33325..33585 | - | 261 | WP_001620096.1 | hypothetical protein | - |
| MW405_RS25105 () | 33883..34743 | + | 861 | WP_001620095.1 | Beta-lactamase SHV-1 | ARG |
| MW405_RS25110 () | 34764..35420 | - | 657 | Protein_38 | DeoR/GlpR family DNA-binding transcription regulator | - |
| MW405_RS25115 () | 35472..36176 | - | 705 | WP_268084103.1 | IS6 family transposase IS26 | Transposase |
| MW405_RS25120 () | 36509..37324 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| MW405_RS25125 () | 37671..39557 | + | 1887 | WP_001332815.1 | FTR1 family protein | - |
| MW405_RS25130 () | 39598..40125 | + | 528 | WP_000178050.1 | iron transporter | - |
| MW405_RS25135 () | 40229..41608 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| MW405_RS25140 () | 41611..42894 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| MW405_RS25145 () | 42884..44014 | + | 1131 | WP_000729218.1 | ABC transporter permease | - |
| MW405_RS25150 () | 44019..44714 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| MW405_RS25155 () | 44701..45186 | + | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| MW405_RS25160 () | 45211..45696 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| MW405_RS25165 () | 45818..46450 | + | 633 | Protein_49 | histidine-type phosphatase | - |
| MW405_RS25170 () | 46600..47579 | - | 980 | Protein_50 | IS5 family transposase ISKpn26 | Transposase |
| MW405_RS25175 () | 47681..48250 | + | 570 | WP_001336919.1 | Serine protease EspC | VF |
| MW405_RS25180 () | 48253..48732 | - | 480 | Protein_52 | IS3 family transposase IS629 | Transposase |
| MW405_RS25185 () | 48816..50324 | - | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| MW405_RS25190 () | 50997..51347 | - | 351 | Protein_54 | IS3 family transposase IS629 | Transposase |
| MW405_RS25195 () | 51433..52932 | + | 1500 | WP_000143800.1 | IS21 family transposase ISEc10 | Transposase |
| MW405_RS25200 () | 52929..53684 | + | 756 | WP_000065240.1 | IS21 family transposase ISEc10 | Transposase |
| MW405_RS25205 () | 53749..54152 | - | 404 | Protein_57 | IS3 family transposase IS629 | Transposase |
| MW405_RS25210 () | 54178..54483 | + | 306 | Protein_58 | IS91 family transposase ISSbo1 | Transposase |
| MW405_RS25215 () | 55006..56181 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| MW405_RS25220 () | 56250..58511 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| MW405_RS25225 () | 58680..59456 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| MW405_RS25230 () | 59464..60339 | - | 876 | WP_001537591.1 | ChaN family lipoprotein | - |
| MW405_RS25235 () | 60671..61357 | - | 687 | Protein_63 | replication initiation protein | - |
| MW405_RS25240 () | 62927..63145 | - | 219 | WP_001336934.1 | hypothetical protein | - |
| MW405_RS25245 () | 63274..63621 | + | 348 | WP_000142452.1 | DUF6404 family protein | - |
| MW405_RS25250 () | 63641..64150 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| MW405_RS25255 () | 64147..64407 | - | 261 | WP_000371883.1 | hypothetical protein | - |
| MW405_RS25260 () | 64509..65248 | + | 740 | Protein_68 | IS3 family transposase IS629 | Transposase |
| MW405_RS25265 () | 65921..67429 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| MW405_RS25270 () | 67519..67992 | + | 474 | Protein_70 | IS3 family transposase IS629 | Transposase |
| MW405_RS25275 () | 68082..68506 | + | 425 | Protein_71 | IS3 family transposase IS2 | Transposase |
| MW405_RS25280 () | 69043..69315 | + | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| MW405_RS25285 () | 69761..69936 | + | 176 | Protein_73 | IS3 family transposase | - |
| MW405_RS25290 () | 70162..71331 | - | 1170 | WP_001072358.1 | hypothetical protein | - |
| MW405_RS25295 () | 71698..71886 | + | 189 | WP_001332784.1 | hypothetical protein | - |
| MW405_RS25300 () | 72007..72747 | + | 741 | WP_001066947.1 | IS91 family transposase ISMno23 | Transposase |
| MW405_RS25305 () | 72990..73967 | - | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| MW405_RS25310 () | 74611..75022 | - | 412 | Protein_78 | DDE-type integrase/transposase/recombinase | - |
| MW405_RS25315 () | 75024..75311 | - | 288 | WP_001270422.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| MW405_RS25320 () | 75308..75559 | - | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| MW405_RS25325 () | 75732..75863 | - | 132 | WP_001309255.1 | hypothetical protein | - |
| MW405_RS25330 () | 76317..77522 | + | 1206 | WP_000817635.1 | Plasmid partition protein A | VF |
| MW405_RS25335 () | 77519..78481 | + | 963 | WP_000756328.1 | ParB family protein | - |
| MW405_RS25340 () | 78715..79491 | + | 777 | Protein_84 | transposase DNA-binding-containing protein | - |
| MW405_RS25345 () | 79621..79704 | - | 84 | Protein_85 | DUF4113 domain-containing protein | - |
| MW405_RS25350 () | 79706..80234 | + | 529 | Protein_86 | DUF1281 domain-containing protein | - |
| MW405_RS25355 () | 80231..80542 | + | 312 | WP_001309256.1 | hypothetical protein | - |
| MW405_RS25360 () | 80618..81301 | + | 684 | WP_000086171.1 | DNA methylase | - |
| MW405_RS25365 () | 81302..81523 | + | 222 | WP_001104892.1 | hypothetical protein | - |
| MW405_RS25370 () | 81453..81971 | + | 519 | WP_224955273.1 | DUF1380 family protein | - |
| MW405_RS25375 () | 82016..82786 | + | 771 | WP_001044390.1 | hypothetical protein | - |
| MW405_RS25380 () | 83200..83625 | + | 426 | WP_001198915.1 | antirestriction protein | - |
| MW405_RS25385 () | 83672..84091 | + | 420 | WP_000271761.1 | DUF1380 family protein | - |
| MW405_RS25390 () | 84091..84282 | + | 192 | WP_001027049.1 | hypothetical protein | - |
| MW405_RS25395 () | 84261..84732 | - | 472 | Protein_95 | hypothetical protein | - |
| MW405_RS25400 () | 85250..85480 | + | 231 | WP_001537563.1 | hypothetical protein | - |
| MW405_RS25405 () | 85532..86893 | + | 1362 | WP_001537564.1 | DUF3560 domain-containing protein | - |
| MW405_RS25410 () | 86940..87503 | + | 564 | WP_001309257.1 | class I SAM-dependent methyltransferase | - |
| MW405_RS25415 () | 87589..88032 | - | 444 | Protein_99 | hypothetical protein | - |
| MW405_RS25420 () | 88334..88861 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| MW405_RS25425 () | 88919..89152 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| MW405_RS25430 () | 89213..91177 | + | 1965 | WP_001537566.1 | ParB/RepB/Spo0J family partition protein | - |
| MW405_RS25435 () | 91246..91680 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| MW405_RS25440 () | 91677..92439 | + | 763 | Protein_104 | plasmid SOS inhibition protein A | - |
| - () | 92408..92632 | + | 225 | NuclAT_0 | - | - |
| - () | 92408..92632 | + | 225 | NuclAT_0 | - | - |
| - () | 92408..92632 | + | 225 | NuclAT_0 | - | - |
| - () | 92408..92632 | + | 225 | NuclAT_0 | - | - |
| MW405_RS25445 () | 92417..92596 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - | 92565..92630 | - | 66 | - | - | Antitoxin Detail |
| MW405_RS25450 () | 92618..92767 | + | 150 | Protein_106 | plasmid maintenance protein Mok | - |
| MW405_RS25455 () | 92709..92834 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| MW405_RS25460 () | 93135..93431 | - | 297 | Protein_108 | hypothetical protein | - |
| MW405_RS25465 () | 93731..94027 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| MW405_RS25470 () | 94137..94958 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| MW405_RS25475 () | 95255..95857 | - | 603 | Protein_111 | hypothetical protein | VF |
| MW405_RS25480 () | 96178..96561 | + | 384 | WP_001151538.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MW405_RS25485 () | 96748..97437 | + | 690 | WP_000283387.1 | conjugal transfer transcriptional regulator TraJ | - |
| MW405_RS25490 () | 97530..97931 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| MW405_RS25495 () | 97964..98323 | + | 360 | WP_001099001.1 | type IV conjugative transfer system pilin TraA | - |
| MW405_RS25500 () | 98338..98649 | + | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| MW405_RS25505 () | 98671..99237 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| MW405_RS25510 () | 99224..99952 | + | 729 | WP_001230767.1 | type-F conjugative transfer system secretin TraK | - |
| MW405_RS25515 () | 99952..101403 | + | 1452 | WP_059331442.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| MW405_RS25520 () | 101393..101959 | + | 567 | WP_000896598.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| MW405_RS25525 () | 101946..102263 | + | 318 | WP_001057297.1 | conjugal transfer protein TrbD | - |
| MW405_RS25530 () | 102263..102778 | + | 516 | WP_000809872.1 | type IV conjugative transfer system lipoprotein TraV | - |
| MW405_RS25535 () | 102913..103134 | + | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| MW405_RS25540 () | 103127..103540 | + | 414 | WP_000549574.1 | hypothetical protein | - |
| MW405_RS25545 () | 103533..104006 | + | 474 | WP_000549566.1 | hypothetical protein | - |
| MW405_RS25550 () | 104086..104304 | + | 219 | WP_000556746.1 | hypothetical protein | - |
| MW405_RS25555 () | 104671..107301 | + | 2631 | WP_000069771.1 | type IV secretion system protein TraC | - |
| MW405_RS25560 () | 107298..107684 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| MW405_RS25565 () | 107681..108313 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| MW405_RS25570 () | 108310..109302 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| MW405_RS25575 () | 109329..109637 | + | 309 | WP_000412445.1 | hypothetical protein | - |
| MW405_RS25580 () | 109700..110218 | + | 519 | WP_000009088.1 | hypothetical protein | - |
| MW405_RS25585 () | 110245..110883 | + | 639 | WP_000087539.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| MW405_RS25590 () | 110880..111251 | + | 372 | WP_000174465.1 | hypothetical protein | - |
| MW405_RS25595 () | 111276..111698 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| MW405_RS25600 () | 111695..113545 | + | 1851 | WP_000826177.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| MW405_RS25605 () | 113572..113829 | + | 258 | WP_000864310.1 | conjugal transfer protein TrbE | - |
| MW405_RS25610 () | 113822..114565 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| MW405_RS25615 () | 114579..114920 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| MW405_RS25620 () | 114976..115236 | - | 261 | WP_000736412.1 | hypothetical protein | - |
| MW405_RS25625 () | 115317..115601 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| MW405_RS25630 () | 115588..116133 | + | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| MW405_RS25635 () | 116123..116437 | + | 315 | WP_001336805.1 | P-type conjugative transfer protein TrbJ | - |
| MW405_RS25640 () | 116391..116783 | + | 393 | WP_000138369.1 | F-type conjugal transfer protein TrbF | - |
| MW405_RS25645 () | 116770..117950 | + | 1181 | WP_268084104.1 | conjugal transfer pilus assembly protein TraH | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|