MGE detailed information
MGE type: Mobilizable plasmid MGE length: 120647 bp
Accession: NZ_CP095427 Location: 1..120647 Organism: Klebsiella pneumoniae strain IM029 Replicon: plasmid pIM029_KPC
Accession: NZ_CP095427 Location: 1..120647 Organism: Klebsiella pneumoniae strain IM029 Replicon: plasmid pIM029_KPC
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MWR69_RS27875 (2) | 2..169 | - | 168 | Protein_0 | conjugal transfer protein TraB | - |
| MWR69_RS27880 (169) | 169..897 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| MWR69_RS27885 (884) | 884..1450 | - | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| MWR69_RS27890 (1472) | 1472..1783 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| MWR69_RS27895 (1798) | 1798..2163 | - | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| MWR69_RS27900 (2197) | 2197..2424 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| MWR69_RS27905 (2518) | 2518..3204 | - | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| MWR69_RS27910 (3395) | 3395..3778 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MWR69_RS27915 (4055) | 4055..4702 | + | 648 | WP_015059008.1 | hypothetical protein | VF |
| MWR69_RS27920 (4999) | 4999..5820 | - | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| MWR69_RS27925 (5931) | 5931..6227 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| MWR69_RS27930 (6527) | 6527..6823 | + | 297 | Protein_11 | hypothetical protein | - |
| MWR69_RS27935 (7142) | 7142..7267 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| MWR69_RS27940 (7209) | 7209..7358 | - | 150 | Protein_13 | plasmid maintenance protein Mok | - |
| - (7344) | 7344..7568 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (7344) | 7344..7568 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (7344) | 7344..7568 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (7344) | 7344..7568 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| MWR69_RS27945 (7580) | 7580..8299 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| MWR69_RS27950 (8296) | 8296..8730 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| MWR69_RS27955 (8799) | 8799..10822 | - | 2024 | Protein_16 | ParB/RepB/Spo0J family partition protein | - |
| MWR69_RS27960 (10883) | 10883..11116 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| MWR69_RS27965 (11174) | 11174..11701 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| MWR69_RS27970 (12003) | 12003..12458 | + | 456 | Protein_19 | hypothetical protein | - |
| MWR69_RS27975 (12544) | 12544..13107 | - | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| MWR69_RS27980 (13154) | 13154..14515 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| MWR69_RS27985 (14567) | 14567..14797 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| MWR69_RS27990 (15314) | 15314..15468 | + | 155 | Protein_23 | hypothetical protein | - |
| MWR69_RS27995 (16197) | 16197..17864 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| MWR69_RS28000 (18178) | 18178..18369 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| MWR69_RS28005 (18366) | 18366..18788 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| MWR69_RS28010 (18835) | 18835..19260 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| MWR69_RS28015 (19678) | 19678..20454 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| MWR69_RS28020 (20505) | 20505..20939 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| MWR69_RS28025 (20953) | 20953..21174 | - | 222 | WP_001104881.1 | hypothetical protein | - |
| MWR69_RS28030 (21175) | 21175..21858 | - | 684 | WP_000085883.1 | DNA methylase | - |
| MWR69_RS28035 (21935) | 21935..22228 | - | 294 | WP_032146011.1 | hypothetical protein | - |
| MWR69_RS28040 (22375) | 22375..23337 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| MWR69_RS28045 (23340) | 23340..23690 | + | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| MWR69_RS28050 (23813) | 23813..24094 | - | 282 | WP_001333089.1 | hypothetical protein | - |
| MWR69_RS28055 (24222) | 24222..24456 | - | 235 | Protein_36 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MWR69_RS28060 (26036) | 26036..26740 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| MWR69_RS28065 (26862) | 26862..27545 | - | 684 | Protein_38 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| MWR69_RS28070 (27610) | 27610..28314 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MWR69_RS28075 (28380) | 28380..28898 | + | 519 | WP_014839979.1 | FidL-like protein | - |
| MWR69_RS28080 (28903) | 28903..29319 | - | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| MWR69_RS28085 (29705) | 29705..30370 | + | 666 | WP_024439608.1 | IS6 family transposase IS15DII | Transposase |
| MWR69_RS28090 (30607) | 30607..31022 | - | 416 | Protein_43 | IS1 family transposase | - |
| MWR69_RS28095 (31271) | 31271..31672 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| MWR69_RS28100 (31605) | 31605..31862 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| MWR69_RS28105 (31955) | 31955..32608 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| MWR69_RS28110 (33547) | 33547..34404 | - | 858 | WP_142295464.1 | incFII family plasmid replication initiator RepA | - |
| MWR69_RS28115 (34397) | 34397..34471 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| MWR69_RS28120 (34716) | 34716..34964 | - | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| MWR69_RS28125 (35248) | 35248..35397 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (35442) | 35442..35501 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (35442) | 35442..35501 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (35442) | 35442..35501 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (35442) | 35442..35501 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| MWR69_RS28130 (35702) | 35702..36034 | - | 333 | WP_152916585.1 | hypothetical protein | - |
| MWR69_RS28135 (36096) | 36096..36695 | - | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| MWR69_RS28140 (37081) | 37081..37281 | - | 201 | WP_015059022.1 | hypothetical protein | - |
| MWR69_RS28145 (37413) | 37413..37973 | - | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| MWR69_RS28150 (38028) | 38028..38774 | - | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| MWR69_RS28155 (38794) | 38794..38994 | - | 201 | WP_072354025.1 | hypothetical protein | - |
| MWR69_RS28160 (39019) | 39019..39723 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MWR69_RS28165 (39776) | 39776..39841 | + | 66 | Protein_58 | helix-turn-helix domain-containing protein | - |
| MWR69_RS28170 (39844) | 39844..42342 | + | 2499 | Protein_59 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| MWR69_RS28175 (42458) | 42458..43462 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| MWR69_RS28180 (43734) | 43734..43820 | - | 87 | Protein_61 | Arm DNA-binding domain-containing protein | - |
| MWR69_RS28185 (43942) | 43942..44166 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| MWR69_RS28190 (44163) | 44163..44900 | - | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| MWR69_RS28195 (45386) | 45386..45526 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| MWR69_RS28200 (45532) | 45532..46255 | - | 724 | Protein_65 | IS6 family transposase IS26 | Transposase |
| MWR69_RS28205 (46246) | 46246..46976 | - | 731 | Protein_66 | helix-turn-helix domain-containing protein | - |
| MWR69_RS28210 (47051) | 47051..47719 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| MWR69_RS28215 (47755) | 47755..47991 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| MWR69_RS28220 (47988) | 47988..48350 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| MWR69_RS28225 (48368) | 48368..50062 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| MWR69_RS28230 (50114) | 50114..50536 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| MWR69_RS28235 (50572) | 50572..50847 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| MWR69_RS28240 (50861) | 50861..51211 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| MWR69_RS28245 (51283) | 51283..51717 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| MWR69_RS28250 (51796) | 51796..52800 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| MWR69_RS28260 (53910) | 53910..54932 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
| MWR69_RS28265 (54917) | 54917..56479 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
| MWR69_RS28270 (56553) | 56553..56969 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| MWR69_RS28275 (56966) | 56966..57196 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| MWR69_RS28280 (57153) | 57153..57614 | + | 462 | WP_014343465.1 | hypothetical protein | - |
| MWR69_RS28285 (57775) | 57775..58719 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| MWR69_RS28290 (58756) | 58756..59148 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| MWR69_RS28295 (59206) | 59206..59727 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| MWR69_RS28300 (59773) | 59773..59976 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| MWR69_RS28305 (60006) | 60006..61010 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| MWR69_RS28310 (61194) | 61194..61973 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| MWR69_RS28315 (62019) | 62019..62276 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| MWR69_RS28320 (62405) | 62405..62518 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| MWR69_RS28325 (63054) | 63054..63920 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| MWR69_RS28330 (65030) | 65030..66235 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| MWR69_RS28335 (66235) | 66235..67209 | + | 975 | WP_011977819.1 | ParB family protein | - |
| MWR69_RS28340 (67291) | 67291..68457 | - | 1167 | Protein_93 | translesion error-prone DNA polymerase V subunit UmuC | - |
| MWR69_RS28345 (68780) | 68780..70267 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| MWR69_RS28350 (70516) | 70516..71487 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| MWR69_RS28355 (71490) | 71490..72161 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| MWR69_RS28360 (72224) | 72224..72454 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| MWR69_RS28365 (72650) | 72650..72819 | + | 170 | Protein_98 | hypothetical protein | - |
| MWR69_RS28370 (72891) | 72891..73592 | + | 702 | WP_151488309.1 | DNA methylase | - |
| MWR69_RS28375 (73592) | 73592..73813 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| MWR69_RS28380 (73823) | 73823..74242 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| MWR69_RS28385 (74296) | 74296..75063 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| MWR69_RS28390 (75744) | 75744..76172 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| MWR69_RS28395 (76215) | 76215..76721 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| MWR69_RS28400 (76764) | 76764..76955 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| MWR69_RS28405 (77143) | 77143..77397 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| MWR69_RS28410 (77432) | 77432..77752 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| MWR69_RS28415 (78432) | 78432..78659 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| MWR69_RS28420 (78751) | 78751..78981 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| MWR69_RS28425 (79033) | 79033..80388 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| MWR69_RS28430 (80436) | 80436..80999 | + | 564 | WP_014343514.1 | methyltransferase | - |
| MWR69_RS28435 (81501) | 81501..82205 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MWR69_RS28440 (82783) | 82783..82887 | - | 105 | Protein_113 | transcriptional regulator | - |
| MWR69_RS28445 (82891) | 82891..83169 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| MWR69_RS28450 (83159) | 83159..83479 | - | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MWR69_RS28455 (83560) | 83560..83784 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| MWR69_RS28460 (83795) | 83795..84007 | - | 213 | WP_014343500.1 | hypothetical protein | - |
| MWR69_RS28465 (84068) | 84068..84424 | - | 357 | WP_014343501.1 | hypothetical protein | - |
| MWR69_RS28470 (85265) | 85265..85582 | - | 318 | WP_014343505.1 | hypothetical protein | - |
| MWR69_RS28475 (85597) | 85597..85947 | - | 351 | WP_040245917.1 | hypothetical protein | - |
| MWR69_RS28480 (85944) | 85944..86216 | - | 273 | WP_040245921.1 | hypothetical protein | - |
| MWR69_RS28485 (86909) | 86909..87028 | - | 120 | WP_159376494.1 | type I toxin-antitoxin system Hok family toxin | - |
| MWR69_RS28490 (86973) | 86973..87125 | - | 153 | WP_004150508.1 | DUF5431 family protein | - |
| MWR69_RS28495 (87295) | 87295..87669 | - | 375 | WP_014343510.1 | hypothetical protein | - |
| MWR69_RS28500 (87725) | 87725..88051 | - | 327 | WP_013023807.1 | hypothetical protein | - |
| MWR69_RS28505 (88048) | 88048..88776 | - | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| MWR69_RS28510 (88773) | 88773..89204 | - | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| MWR69_RS28515 (89249) | 89249..91306 | - | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| MWR69_RS28520 (91376) | 91376..91624 | - | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| MWR69_RS28525 (91673) | 91673..92215 | - | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| MWR69_RS28530 (92670) | 92670..93374 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MWR69_RS28535 (93703) | 93703..94653 | + | 951 | WP_015493085.1 | Recombination-promoting nuclease RpnA | VF |
| MWR69_RS28540 (94650) | 94650..95261 | - | 612 | WP_015493086.1 | DUF2913 family protein | - |
| MWR69_RS28545 (95258) | 95258..95653 | - | 396 | WP_015493087.1 | hypothetical protein | - |
| MWR69_RS28550 (95706) | 95706..96044 | - | 339 | Protein_135 | 3'-5' exonuclease | - |
| MWR69_RS28555 (96082) | 96082..97062 | + | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| MWR69_RS28560 (97044) | 97044..97658 | + | 615 | WP_271259474.1 | hypothetical protein | - |
| MWR69_RS28565 (98127) | 98127..98831 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MWR69_RS28570 (98884) | 98884..99957 | - | 1074 | Protein_139 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| MWR69_RS28575 (99961) | 99961..100521 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| MWR69_RS28580 (100913) | 100913..101530 | + | 618 | Protein_141 | replication protein | - |
| MWR69_RS28585 (102064) | 102064..102342 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| MWR69_RS28590 (102453) | 102453..102878 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| MWR69_RS28595 (103006) | 103006..103161 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| MWR69_RS28600 (103207) | 103207..103503 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| MWR69_RS28605 (103607) | 103607..104488 | + | 882 | Protein_146 | IS1182 family transposase ISKpn6 | Transposase |
| MWR69_RS28610 (104738) | 104738..105619 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| MWR69_RS28615 (105895) | 105895..106875 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| MWR69_RS28620 (106998) | 106998..107459 | - | 462 | Protein_149 | Tn3 family transposase TnpR_Tn3 | Transposase |
| MWR69_RS28625 (107511) | 107511..108215 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MWR69_RS28630 (108281) | 108281..110179 | + | 1899 | Protein_151 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| MWR69_RS28635 (110215) | 110215..110283 | - | 69 | Protein_152 | IS6 family transposase | - |
| MWR69_RS28640 (110420) | 110420..111280 | + | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| MWR69_RS28645 (111301) | 111301..112062 | - | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| MWR69_RS28650 (112324) | 112324..113226 | + | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| MWR69_RS28655 (113238) | 113238..114490 | + | 1253 | Protein_156 | four-carbon acid sugar kinase family protein | - |
| MWR69_RS28660 (114483) | 114483..114818 | + | 336 | Protein_157 | class II aldolase/adducin family protein | - |
| MWR69_RS28665 (114873) | 114873..115577 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MWR69_RS28670 (115621) | 115621..116132 | - | 512 | Protein_159 | type-F conjugative transfer system secretin TraK | - |
| MWR69_RS28675 (116119) | 116119..116684 | - | 566 | Protein_160 | type IV conjugative transfer system protein TraE | - |
| MWR69_RS28680 (116706) | 116706..117016 | - | 311 | Protein_161 | type IV conjugative transfer system protein TraL | - |
| MWR69_RS28685 (117031) | 117031..117395 | - | 365 | Protein_162 | type IV conjugative transfer system pilin TraA | - |
| MWR69_RS28690 (117429) | 117429..117656 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| MWR69_RS28695 (117750) | 117750..118436 | - | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| MWR69_RS28700 (118627) | 118627..119010 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MWR69_RS28705 (119285) | 119285..119932 | + | 648 | WP_015059008.1 | hypothetical protein | VF |
| MWR69_RS28710 (120229) | 120229..120647 | - | 419 | Protein_167 | DUF932 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|