MGE detailed information
MGE type: Conjugative plasmid MGE length: 126021 bp
Accession: NZ_CP091535 Location: 1..126021 Organism: Escherichia coli strain 537-20 Replicon: plasmid p537-20_1
Accession: NZ_CP091535 Location: 1..126021 Organism: Escherichia coli strain 537-20 Replicon: plasmid p537-20_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L6D13_RS23930 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| L6D13_RS23935 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| L6D13_RS23940 (2124) | 2124..2321 | - | 198 | WP_187184112.1 | serine/threonine protein kinase | - |
| L6D13_RS23945 (2694) | 2694..3592 | - | 899 | Protein_3 | hypothetical protein | VF |
| L6D13_RS23950 (3661) | 3661..4770 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| L6D13_RS23955 (5200) | 5200..6153 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| L6D13_RS23960 (7447) | 7447..7626 | - | 180 | Protein_6 | integrase core domain-containing protein | - |
| L6D13_RS23965 (7765) | 7765..8964 | + | 1200 | Protein_7 | IS3 family transposase IS629 | Transposase |
| L6D13_RS23970 (9112) | 9112..9437 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| L6D13_RS23975 (9483) | 9483..9823 | + | 341 | Protein_9 | IS3 family transposase | - |
| L6D13_RS23980 (10418) | 10418..11605 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| L6D13_RS23985 (11602) | 11602..13542 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| L6D13_RS23990 (13546) | 13546..14916 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| L6D13_RS23995 (15391) | 15391..15585 | + | 195 | Protein_13 | IS200-IS605 family transposase IS200C | Transposase |
| L6D13_RS24000 (15714) | 15714..16655 | - | 942 | WP_023351706.1 | hypothetical protein | - |
| L6D13_RS24005 (16890) | 16890..18279 | - | 1390 | Protein_15 | ISNCY family transposase ISKpn21 | Transposase |
| L6D13_RS24010 (18589) | 18589..18738 | - | 150 | Protein_16 | IS3 family transposase | - |
| L6D13_RS24015 (18915) | 18915..20108 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| L6D13_RS24020 (21350) | 21350..22090 | - | 741 | Protein_18 | IS3 family transposase IS2 | Transposase |
| L6D13_RS24025 (22131) | 22131..23299 | + | 1169 | WP_085962211.1 | IS3 family transposase ISEc17 | Transposase |
| L6D13_RS24030 (23316) | 23316..23836 | - | 521 | Protein_20 | IS3 family transposase IS2 | Transposase |
| L6D13_RS24035 (24461) | 24461..24754 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| L6D13_RS24045 (24812) | 24812..25011 | - | 200 | Protein_22 | lysis protein | - |
| L6D13_RS24050 (25565) | 25565..26589 | + | 1025 | Protein_23 | integrase core domain-containing protein | - |
| L6D13_RS24055 (27900) | 27900..29015 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| L6D13_RS24060 (29155) | 29155..32814 | + | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| L6D13_RS24065 (32918) | 32918..34147 | + | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| L6D13_RS24070 (34232) | 34232..35188 | + | 957 | WP_000271274.1 | Ferri-bacillibactin esterase BesA | VF |
| L6D13_RS24075 (35233) | 35233..37410 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| L6D13_RS24080 (38276) | 38276..39310 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| L6D13_RS24085 (39491) | 39491..39792 | + | 302 | Protein_30 | hypothetical protein | - |
| L6D13_RS24090 (39870) | 39870..40163 | - | 294 | WP_000269327.1 | DUF6404 family protein | - |
| L6D13_RS24095 (40331) | 40331..40456 | - | 126 | Protein_32 | type II toxin-antitoxin system toxin YacB | - |
| L6D13_RS24100 (40456) | 40456..40724 | - | 269 | Protein_33 | type II toxin-antitoxin system antitoxin YacA | - |
| L6D13_RS24105 (41335) | 41335..42609 | + | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| L6D13_RS24110 (42602) | 42602..44698 | + | 2097 | WP_000184924.1 | microcin H47 export transporter peptidase/ATP-binding subunit MchF | - |
| L6D13_RS24115 (44868) | 44868..45179 | - | 312 | WP_001259758.1 | colicin V | - |
| L6D13_RS24120 (45157) | 45157..45393 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| L6D13_RS24125 (45512) | 45512..45955 | + | 444 | WP_001323891.1 | dehydrogenase | - |
| L6D13_RS24130 (45927) | 45927..46331 | + | 405 | WP_001389361.1 | hypothetical protein | - |
| L6D13_RS24135 (46333) | 46333..46602 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| L6D13_RS24140 (46599) | 46599..47579 | + | 981 | WP_001017346.1 | NAD(P)-binding domain-containing protein | - |
| L6D13_RS24145 (47655) | 47655..48035 | + | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| L6D13_RS24150 (48032) | 48032..48379 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| L6D13_RS24155 (48429) | 48429..49966 | + | 1538 | Protein_44 | IS66 family transposase ISEc8 | Transposase |
| L6D13_RS24160 (50006) | 50006..50272 | + | 267 | Protein_45 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| L6D13_RS24165 (50319) | 50319..50711 | - | 393 | Protein_46 | peptide deformylase | - |
| L6D13_RS24170 (50820) | 50820..54953 | - | 4134 | WP_001080137.1 | Temperature-sensitive hemagglutinin tsh autotransporter | VF |
| L6D13_RS24175 (55124) | 55124..55315 | + | 192 | Protein_48 | IS91 family transposase | - |
| L6D13_RS24185 (55594) | 55594..55851 | + | 258 | Protein_49 | IS3 family transposase IS911 | Transposase |
| L6D13_RS24190 (55919) | 55919..57070 | + | 1152 | WP_001442799.1 | IS30 family transposase IS30D | Transposase |
| L6D13_RS24195 (57192) | 57192..57557 | + | 366 | WP_000124098.1 | hypothetical protein | - |
| L6D13_RS24200 (57557) | 57557..58672 | + | 1116 | Protein_52 | IS91 family transposase IS91 | Transposase |
| L6D13_RS24205 (58853) | 58853..59197 | - | 345 | WP_001553768.1 | hypothetical protein | - |
| L6D13_RS24210 (60133) | 60133..60990 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| L6D13_RS24215 (60983) | 60983..61465 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| L6D13_RS24220 (61458) | 61458..61505 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| L6D13_RS24225 (61496) | 61496..61747 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| L6D13_RS24230 (61764) | 61764..62021 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| L6D13_RS24235 (62305) | 62305..62454 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (62498) | 62498..62559 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (62498) | 62498..62559 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (62498) | 62498..62559 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (62498) | 62498..62559 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| L6D13_RS24240 (62815) | 62815..62889 | - | 75 | Protein_60 | endonuclease | - |
| L6D13_RS24245 (63135) | 63135..63347 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| L6D13_RS24250 (63483) | 63483..64043 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| L6D13_RS24255 (64146) | 64146..65006 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| L6D13_RS24260 (65065) | 65065..65811 | - | 747 | WP_236932592.1 | conjugal transfer pilus acetylase TraX | - |
| L6D13_RS24265 (65831) | 65831..71101 | - | 5271 | WP_000986963.1 | Multifunctional conjugation protein TraI | Relaxase |
| L6D13_RS24270 (71183) | 71183..71410 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | - |
| L6D13_RS24275 (71410) | 71410..71808 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| L6D13_RS24280 (71817) | 71817..73970 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| L6D13_RS24285 (74223) | 74223..74954 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| L6D13_RS24290 (74986) | 74986..75483 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| L6D13_RS24295 (75499) | 75499..78321 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| L6D13_RS24300 (78318) | 78318..79691 | - | 1374 | WP_236932594.1 | conjugal transfer pilus assembly protein TraH | - |
| L6D13_RS24305 (79691) | 79691..80071 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| L6D13_RS24310 (80058) | 80058..80399 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| L6D13_RS24315 (80329) | 80329..80874 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| L6D13_RS24320 (80861) | 80861..81145 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| L6D13_RS24325 (81226) | 81226..81540 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| L6D13_RS24330 (81542) | 81542..81889 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| L6D13_RS24335 (81905) | 81905..82648 | - | 744 | WP_001030377.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| L6D13_RS24340 (82641) | 82641..82898 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| L6D13_RS24345 (82925) | 82925..84733 | - | 1809 | WP_000821838.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| L6D13_RS24350 (84730) | 84730..85368 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| L6D13_RS24355 (85377) | 85377..86369 | - | 993 | WP_000830181.1 | conjugal transfer pilus assembly protein TraU | - |
| L6D13_RS24360 (86366) | 86366..86998 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| L6D13_RS24365 (86995) | 86995..87381 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| L6D13_RS24370 (87378) | 87378..90005 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| L6D13_RS24375 (90165) | 90165..90386 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| L6D13_RS24380 (90521) | 90521..91036 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| L6D13_RS24385 (91033) | 91033..91284 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| L6D13_RS24390 (91296) | 91296..91493 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| L6D13_RS24395 (91480) | 91480..92070 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| L6D13_RS24400 (92060) | 92060..93487 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| L6D13_RS24405 (93487) | 93487..94215 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| L6D13_RS24410 (94202) | 94202..94768 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| L6D13_RS24415 (94790) | 94790..95101 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| L6D13_RS24420 (95116) | 95116..95481 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| L6D13_RS24425 (95514) | 95514..95915 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| L6D13_RS24430 (96008) | 96008..96696 | - | 689 | Protein_98 | conjugal transfer transcriptional regulator TraJ | - |
| L6D13_RS24435 (96883) | 96883..97266 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| L6D13_RS24440 (97587) | 97587..98189 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| L6D13_RS24445 (98486) | 98486..99307 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| L6D13_RS24450 (99425) | 99425..99712 | - | 288 | WP_236932593.1 | hypothetical protein | - |
| L6D13_RS24455 (99737) | 99737..99943 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| L6D13_RS24460 (100013) | 100013..100185 | + | 173 | Protein_104 | hypothetical protein | - |
| L6D13_RS24465 (100183) | 100183..100413 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| L6D13_RS24470 (100633) | 100633..100758 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| L6D13_RS24475 (100700) | 100700..100849 | - | 150 | Protein_107 | plasmid maintenance protein Mok | - |
| - (100835) | 100835..101059 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (100835) | 100835..101059 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (100835) | 100835..101059 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (100835) | 100835..101059 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| L6D13_RS24480 (100871) | 100871..101059 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| L6D13_RS24485 (101028) | 101028..101790 | - | 763 | Protein_109 | plasmid SOS inhibition protein A | - |
| L6D13_RS24490 (101787) | 101787..102221 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| L6D13_RS24495 (102276) | 102276..102473 | - | 198 | Protein_111 | hypothetical protein | - |
| L6D13_RS24500 (102501) | 102501..102734 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| L6D13_RS24505 (102802) | 102802..103341 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| L6D13_RS24510 (103367) | 103367..103573 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| L6D13_RS24515 (103643) | 103643..103723 | + | 81 | Protein_115 | hypothetical protein | - |
| L6D13_RS24520 (103906) | 103906..104075 | - | 170 | Protein_116 | hypothetical protein | - |
| L6D13_RS24525 (104669) | 104669..105640 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| L6D13_RS24530 (105640) | 105640..106806 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| L6D13_RS24540 (108159) | 108159..109073 | + | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| L6D13_RS24545 (109073) | 109073..109900 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| L6D13_RS24550 (109897) | 109897..110754 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| L6D13_RS24555 (110751) | 110751..111608 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| L6D13_RS24560 (111842) | 111842..112099 | - | 258 | Protein_124 | Tn3 family transposase | - |
| L6D13_RS24565 (112097) | 112097..112510 | + | 414 | Protein_125 | phosphopyruvate hydratase | - |
| L6D13_RS24570 (112851) | 112851..113231 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| L6D13_RS24575 (113611) | 113611..114804 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| L6D13_RS24580 (114940) | 114940..116664 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| L6D13_RS24585 (116665) | 116665..117612 | + | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| L6D13_RS24590 (117612) | 117612..119354 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| L6D13_RS24595 (119351) | 119351..120684 | + | 1334 | Protein_131 | L-lysine N6-monooxygenase | VF |
| L6D13_RS24600 (120710) | 120710..122911 | + | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| L6D13_RS24605 (123396) | 123396..124093 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| L6D13_RS24610 (124273) | 124273..124786 | - | 514 | Protein_134 | DUF4113 domain-containing protein | - |
| L6D13_RS24615 (124847) | 124847..124951 | - | 105 | Protein_135 | AAA family ATPase | - |
| L6D13_RS24620 (124953) | 124953..125276 | - | 324 | Protein_136 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|