NZ_CP0914281..145445

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 145445 bp
Accession: NZ_CP091428        Location: 1..145445         Organism: Escherichia coli strain 1000C-3       Replicon: plasmid pMHW-2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Z43_RS23240 (1) 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
L3Z43_RS23245 (1263) 1263..2003 - 741 WP_001066953.1 tyrosine-type recombinase/integrase -
L3Z43_RS23250 (2124) 2124..2312 - 189 WP_001309252.1 hypothetical protein -
L3Z43_RS23255 (2679) 2679..3848 + 1170 WP_001072358.1 hypothetical protein -
L3Z43_RS23260 (4074) 4074..4249 - 176 Protein_4 IS3 family transposase -
L3Z43_RS23265 (4695) 4695..4967 - 273 WP_001322642.1 adhesin biosynthesis transcription regulatory family protein -
L3Z43_RS23270 (5492) 5492..5924 - 433 Protein_6 transposase -
L3Z43_RS23275 (6206) 6206..8176 + 1971 WP_001496335.1 Hemin receptor VF
L3Z43_RS23280 (8183) 8183..8974 + 792 WP_000977394.1 DUF4198 domain-containing protein -
L3Z43_RS23285 (9037) 9037..9645 - 609 Protein_9 IS66 family transposase ISEc22 Transposase
L3Z43_RS23290 (9713) 9713..10495 - 783 WP_001317493.1 IS21 family transposase IS100kyp Transposase
L3Z43_RS23295 (10492) 10492..11514 - 1023 WP_000255956.1 IS21 family transposase IS100kyp Transposase
L3Z43_RS23300 (11600) 11600..12544 - 945 Protein_12 IS66 family transposase -
L3Z43_RS23305 (12593) 12593..12967 - 375 WP_239804102.1 IS66 family transposase ISEc22 Transposase
L3Z43_RS23310 (12992) 12992..13695 + 704 Protein_14 IS6 family transposase IS15DII Transposase
L3Z43_RS23315 (13755) 13755..14768 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
L3Z43_RS23320 (14926) 14926..15399 + 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
L3Z43_RS23325 (15530) 15530..16318 + 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
L3Z43_RS23330 (16524) 16524..16871 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
L3Z43_RS23335 (16865) 16865..17704 + 840 WP_239804103.1 Dihydropteroate synthase ARG
L3Z43_RS23340 (17832) 17832..18035 + 204 WP_000376616.1 hypothetical protein -
L3Z43_RS23345 (18191) 18191..19396 + 1206 WP_000184001.1 chromate efflux transporter -
L3Z43_RS23350 (19407) 19407..19712 + 306 WP_000130000.1 hypothetical protein Relaxase
L3Z43_RS23355 (19756) 19756..19821 + 66 Protein_23 EAL domain-containing protein -
L3Z43_RS23360 (19939) 19939..20703 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
L3Z43_RS23365 (21196) 21196..21780 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
L3Z43_RS23370 (21780) 21780..23018 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
L3Z43_RS23375 (23015) 23015..23920 - 906 WP_000219391.1 hypothetical protein ARG
L3Z43_RS23380 (24042) 24042..24745 - 704 Protein_28 IS6 family transposase IS15DII Transposase
L3Z43_RS23385 (24822) 24822..27039 - 2218 Protein_29 Tn3 family transposase TnpA_Tn3 Transposase
L3Z43_RS23390 (27104) 27104..27396 + 293 Protein_30 WbuC family cupin fold metalloprotein -
L3Z43_RS23395 (27443) 27443..28318 - 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
L3Z43_RS23400 (28574) 28574..28861 - 288 Protein_32 transposase -
L3Z43_RS23405 (28927) 28927..29631 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
L3Z43_RS23410 (29685) 29685..30125 - 441 Protein_34 CatB-related O-acetyltransferase -
L3Z43_RS23415 (30261) 30261..31091 - 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
L3Z43_RS23420 (31222) 31222..31776 - 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
L3Z43_RS23425 (31920) 31920..32624 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
L3Z43_RS23430 (32690) 32690..34202 + 1513 Protein_38 Tn3 family transposase TnpA_TnAs1 Transposase
L3Z43_RS23435 (34270) 34270..34485 + 216 Protein_39 relaxase -
L3Z43_RS23440 (34517) 34517..35166 - 650 Protein_40 tetracycline resistance transcriptional repressor TetR(A) -
L3Z43_RS23445 (35272) 35272..36470 + 1199 Protein_41 Tetracycline resistance protein, class C ARG
L3Z43_RS23450 (36502) 36502..37385 - 884 Protein_42 EamA family transporter -
L3Z43_RS23455 (37523) 37523..37915 - 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
L3Z43_RS23460 (37919) 37919..38666 + 748 Protein_44 Tn3 family transposase -
L3Z43_RS23465 (38690) 38690..39295 - 606 WP_000509965.1 Tn3 family transposase TnpR_Tn5403 Transposase
L3Z43_RS23470 (39390) 39390..42284 + 2895 Protein_46 Tn3-like element Tn5403 family transposase -
L3Z43_RS23475 (42421) 42421..42822 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
L3Z43_RS23480 (42755) 42755..43012 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
L3Z43_RS23485 (43105) 43105..43758 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
L3Z43_RS23490 (44696) 44696..45549 - 854 Protein_50 incFII family plasmid replication initiator RepA -
L3Z43_RS23495 (45542) 45542..45616 - 75 WP_001365705.1 RepA leader peptide Tap -
L3Z43_RS23500 (45852) 45852..46109 - 258 WP_000083821.1 replication regulatory protein RepA -
L3Z43_RS23505 (46513) 46513..47533 + 1021 Protein_53 IS110 family transposase ISSm1 Transposase
L3Z43_RS23510 (48005) 48005..48253 + 249 WP_239804104.1 hypothetical protein -
L3Z43_RS23515 (48768) 48768..49345 - 578 Protein_55 DUF2726 domain-containing protein -
L3Z43_RS23520 (49378) 49378..49677 + 300 WP_239804105.1 IS1-like element transposase -
L3Z43_RS23525 (49697) 49697..50070 + 374 Protein_57 IS1 family transposase -
L3Z43_RS23530 (50179) 50179..50598 + 420 WP_239804109.1 transposase -
L3Z43_RS23535 (50537) 50537..50886 + 350 Protein_59 IS66 family transposase ISEc23 Transposase
L3Z43_RS23540 (50911) 50911..51429 + 519 Protein_60 IS66 family transposase ISEc47 Transposase
L3Z43_RS23545 (51493) 51493..51970 - 478 Protein_61 ArgR family transcriptional regulator -
L3Z43_RS23550 (52051) 52051..53454 - 1404 Protein_62 YfcC family protein -
L3Z43_RS24525 (53501) 53501..54500 - 1000 Protein_63 ornithine carbamoyltransferase -
L3Z43_RS23570 (54584) 54584..55495 - 912 WP_239804108.1 carbamate kinase -
L3Z43_RS23575 (55506) 55506..56724 - 1219 Protein_65 arginine deiminase -
L3Z43_RS23580 (57430) 57430..58044 + 615 Protein_66 VENN motif pre-toxin domain-containing protein -
L3Z43_RS23585 (58044) 58044..58488 - 445 Protein_67 plasmid replication initiator RepA -
L3Z43_RS23590 (58481) 58481..58555 - 75 WP_032336874.1 RepA leader peptide Tap -
L3Z43_RS23595 (58791) 58791..59048 - 258 WP_000083833.1 replication regulatory protein RepA -
L3Z43_RS23600 (59329) 59329..59478 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (59522) 59522..59583 + 62 NuclAT_2 - Antitoxin Detail
- (59522) 59522..59583 + 62 NuclAT_2 - Antitoxin Detail
- (59522) 59522..59583 + 62 NuclAT_2 - Antitoxin Detail
- (59522) 59522..59583 + 62 NuclAT_2 - Antitoxin Detail
L3Z43_RS23605 (59722) 59722..59904 - 183 WP_000968309.1 hypothetical protein -
L3Z43_RS23610 (60005) 60005..60619 + 615 Protein_72 IS1-like element IS1A family transposase -
L3Z43_RS23615 (60657) 60657..62228 - 1572 WP_023149734.1 IS66 family transposase ISCro1 Transposase
L3Z43_RS23620 (62248) 62248..62595 - 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
L3Z43_RS23625 (62595) 62595..63272 - 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
L3Z43_RS23630 (63327) 63327..63416 + 90 Protein_76 IS1 family transposase -
L3Z43_RS23635 (63717) 63717..63929 - 213 WP_005012601.1 hypothetical protein -
L3Z43_RS23640 (64063) 64063..64623 - 561 WP_000139363.1 fertility inhibition protein FinO -
L3Z43_RS23645 (64678) 64678..65424 - 747 WP_023149624.1 conjugal transfer pilus acetylase TraX -
L3Z43_RS23650 (65444) 65444..70564 - 5121 WP_013362805.1 Multifunctional conjugation protein TraI Relaxase
L3Z43_RS23655 (70564) 70564..72753 - 2190 WP_040110343.1 type IV conjugative transfer system coupling protein TraD -
L3Z43_RS23660 (73005) 73005..73736 - 732 WP_000850424.1 conjugal transfer complement resistance protein TraT -
L3Z43_RS23665 (73750) 73750..74259 - 510 WP_000628100.1 conjugal transfer entry exclusion protein TraS -
L3Z43_RS23670 (74256) 74256..75176 - 921 Protein_84 conjugal transfer protein TraG -
L3Z43_RS23675 (75229) 75229..75929 - 701 Protein_85 IS6-like element IS26 family transposase -
L3Z43_RS23680 (75992) 75992..77905 - 1914 Protein_86 conjugal transfer mating-pair stabilization protein TraG -
L3Z43_RS23685 (77902) 77902..79275 - 1374 WP_021518370.1 conjugal transfer pilus assembly protein TraH -
L3Z43_RS23690 (79262) 79262..79654 - 393 WP_000164675.1 F-type conjugal transfer protein TrbF -
L3Z43_RS23695 (79608) 79608..79922 - 315 WP_023149603.1 P-type conjugative transfer protein TrbJ -
L3Z43_RS23700 (79912) 79912..80466 - 555 WP_001553830.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
L3Z43_RS23705 (80453) 80453..80722 - 270 WP_239804101.1 type-F conjugative transfer system pilin chaperone TraQ -
L3Z43_RS23710 (80803) 80803..81138 + 336 WP_000415571.1 hypothetical protein -
L3Z43_RS23715 (81119) 81119..81460 - 342 WP_000556794.1 conjugal transfer protein TrbA -
L3Z43_RS23720 (81474) 81474..82217 - 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
L3Z43_RS23725 (82210) 82210..82467 - 258 WP_000864312.1 conjugal transfer protein TrbE -
L3Z43_RS23730 (82494) 82494..84302 - 1809 WP_000821840.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
L3Z43_RS23735 (84299) 84299..84937 - 639 WP_021518374.1 type-F conjugative transfer system pilin assembly protein TrbC -
L3Z43_RS23740 (84946) 84946..85938 - 993 WP_000830180.1 conjugal transfer pilus assembly protein TraU -
L3Z43_RS23745 (85935) 85935..86567 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
L3Z43_RS23750 (86564) 86564..86950 - 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
L3Z43_RS23755 (86947) 86947..89574 - 2628 WP_001064245.1 type IV secretion system protein TraC -
L3Z43_RS23760 (89734) 89734..89955 - 222 WP_001278689.1 conjugal transfer protein TraR -
L3Z43_RS23765 (90090) 90090..90605 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
L3Z43_RS23770 (90602) 90602..90853 - 252 WP_001038342.1 conjugal transfer protein TrbG -
L3Z43_RS23775 (90865) 90865..91062 - 198 WP_001324648.1 conjugal transfer protein TrbD -
L3Z43_RS23780 (91049) 91049..91639 - 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
L3Z43_RS23785 (91629) 91629..93056 - 1428 WP_001825178.1 F-type conjugal transfer pilus assembly protein TraB -
L3Z43_RS23790 (93056) 93056..93784 - 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
L3Z43_RS23795 (93771) 93771..94337 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
L3Z43_RS23800 (94359) 94359..94670 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
L3Z43_RS23805 (94685) 94685..95050 - 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
L3Z43_RS23810 (95083) 95083..95484 - 402 WP_001369361.1 conjugal transfer relaxosome DNA-bindin protein TraY -
L3Z43_RS23815 (95577) 95577..96266 - 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
L3Z43_RS23820 (96453) 96453..96836 - 384 WP_001151524.1 conjugal transfer relaxosome DNA-binding protein TraM -
L3Z43_RS23825 (97154) 97154..97756 + 603 WP_013362798.1 hypothetical protein VF
L3Z43_RS23830 (98053) 98053..98874 - 822 WP_001234426.1 DUF932 domain-containing protein -
L3Z43_RS23835 (98992) 98992..99279 - 288 WP_000107535.1 hypothetical protein -
L3Z43_RS23840 (99579) 99579..99747 + 169 Protein_118 hypothetical protein -
L3Z43_RS23845 (99747) 99747..99977 - 231 WP_071886920.1 hypothetical protein -
L3Z43_RS23850 (100197) 100197..100322 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
L3Z43_RS23855 (100264) 100264..100413 - 150 Protein_121 plasmid maintenance protein Mok -
- (100399) 100399..100430 - 32 NuclAT_1 - Antitoxin Detail
- (100399) 100399..100430 - 32 NuclAT_1 - Antitoxin Detail
- (100399) 100399..100430 - 32 NuclAT_1 - Antitoxin Detail
- (100399) 100399..100430 - 32 NuclAT_1 - Antitoxin Detail
L3Z43_RS23860 (100455) 100455..101818 - 1364 Protein_122 IS3-like element IS150 family transposase -
- (101866) 101866..102063 - 198 NuclAT_0 - -
- (101866) 101866..102063 - 198 NuclAT_0 - -
- (101866) 101866..102063 - 198 NuclAT_0 - -
- (101866) 101866..102063 - 198 NuclAT_0 - -
L3Z43_RS23865 (101875) 101875..102063 + 189 WP_001299721.1 hypothetical protein -
L3Z43_RS23870 (102032) 102032..102794 - 763 Protein_124 plasmid SOS inhibition protein A -
L3Z43_RS23875 (102791) 102791..103225 - 435 WP_000845937.1 conjugation system SOS inhibitor PsiB -
L3Z43_RS23880 (103280) 103280..103477 - 198 Protein_126 hypothetical protein -
L3Z43_RS23885 (103505) 103505..103738 - 234 WP_000006030.1 DUF905 family protein -
L3Z43_RS23890 (103800) 103800..104297 - 498 WP_061310956.1 single-stranded DNA-binding protein -
L3Z43_RS23895 (104447) 104447..106348 - 1902 WP_000936285.1 group II intron reverse transcriptase/maturase -
L3Z43_RS23900 (107026) 107026..107232 - 207 WP_000275856.1 hypothetical protein -
L3Z43_RS23905 (107472) 107472..107723 - 252 WP_071579736.1 hypothetical protein -
L3Z43_RS23910 (107642) 107642..107848 - 207 WP_001774176.1 hypothetical protein -
L3Z43_RS23915 (107874) 107874..108439 - 566 Protein_133 class I SAM-dependent methyltransferase -
L3Z43_RS23920 (108487) 108487..109848 - 1362 WP_000199439.1 DUF3560 domain-containing protein -
L3Z43_RS23925 (109900) 109900..110130 - 231 WP_000218642.1 hypothetical protein -
L3Z43_RS23930 (110642) 110642..110890 + 249 WP_071781657.1 hypothetical protein -
L3Z43_RS23935 (111162) 111162..111353 - 192 WP_001027495.1 hypothetical protein -
L3Z43_RS23940 (111350) 111350..111772 - 423 WP_000271685.1 DUF1380 family protein -
L3Z43_RS23945 (111819) 111819..112244 - 426 WP_001546490.1 antirestriction protein -
L3Z43_RS23950 (112658) 112658..113428 - 771 WP_001006251.1 hypothetical protein -
L3Z43_RS23955 (113473) 113473..113991 - 519 WP_223349485.1 DUF1380 family protein -
L3Z43_RS23960 (113921) 113921..114142 - 222 WP_001104873.1 hypothetical protein -
L3Z43_RS23965 (114143) 114143..114826 - 684 WP_032181561.1 DNA methylase -
L3Z43_RS23970 (114903) 114903..115214 - 312 WP_012615291.1 hypothetical protein -
L3Z43_RS23975 (115211) 115211..116113 - 903 WP_064766247.1 DUF1281 domain-containing protein -
L3Z43_RS23980 (116851) 116851..117822 - 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
L3Z43_RS23985 (117822) 117822..118988 - 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
L3Z43_RS23990 (119576) 119576..120331 - 756 WP_000852146.1 replication initiation protein RepE -
L3Z43_RS23995 (121053) 121053..121859 - 807 WP_000016970.1 site-specific integrase -
L3Z43_RS24000 (121860) 121860..122165 - 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
L3Z43_RS24005 (122167) 122167..122385 - 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
L3Z43_RS24010 (122945) 122945..123175 + 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
L3Z43_RS24015 (123172) 123172..123588 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
L3Z43_RS24020 (123663) 123663..125228 + 1566 WP_001128474.1 AAA family ATPase -
L3Z43_RS24025 (125213) 125213..126235 + 1023 WP_000361402.1 helicase UvrD -
L3Z43_RS24035 (127712) 127712..129913 - 2202 WP_000973519.1 Ferric aerobactin receptor VF
L3Z43_RS24040 (129939) 129939..131272 - 1334 Protein_158 L-lysine N6-monooxygenase VF
L3Z43_RS24045 (131269) 131269..133011 - 1743 WP_001015721.1 Aerobactin synthase VF
L3Z43_RS24050 (133011) 133011..133958 - 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase VF
L3Z43_RS24055 (133959) 133959..135683 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
L3Z43_RS24060 (135819) 135819..137012 + 1194 WP_000095526.1 MFS transporter -
L3Z43_RS24065 (137392) 137392..137772 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
L3Z43_RS24070 (138113) 138113..138526 - 414 Protein_164 phosphopyruvate hydratase -
L3Z43_RS24075 (138524) 138524..138781 + 258 Protein_165 Tn3 family transposase -
L3Z43_RS24080 (139015) 139015..139872 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
L3Z43_RS24085 (139869) 139869..140726 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
L3Z43_RS24090 (140723) 140723..141550 - 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
L3Z43_RS24095 (141550) 141550..142464 - 915 WP_000949005.1 Putative metal ABC transporter substrate-binding protein Hpf VF
L3Z43_RS24100 (142820) 142820..143517 + 698 WP_103215986.1 IS1 family transposase IS1G Transposase
L3Z43_RS24105 (143697) 143697..144210 - 514 Protein_171 DUF4113 domain-containing protein -
L3Z43_RS24110 (144271) 144271..144375 - 105 Protein_172 AAA family ATPase -
L3Z43_RS24115 (144377) 144377..144700 - 324 Protein_173 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance