MGE detailed information

MGE type: Conjugative plasmid        MGE length: 140550 bp
Accession: NZ_CP088995        Location: 1..140550         Organism: Klebsiella pneumoniae strain 50700       Replicon: plasmid p50700-140.6


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRZ81_RS27615 (1) 1..858 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
LRZ81_RS27620 (1797) 1797..2450 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LRZ81_RS27625 (2543) 2543..2800 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LRZ81_RS27630 (2733) 2733..3134 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LRZ81_RS27635 (3383) 3383..3798 + 416 Protein_4 IS1-like element IS1B family transposase -
LRZ81_RS27640 (3834) 3834..4379 - 546 Protein_5 Tn3 family transposase TnpA_Tn3 Transposase
LRZ81_RS27645 (4445) 4445..5149 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LRZ81_RS27650 (5219) 5219..5410 + 192 Protein_7 IS1380 family transposase -
LRZ81_RS27655 (5660) 5660..6535 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
LRZ81_RS27660 (6570) 6570..7538 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
LRZ81_RS27665 (7595) 7595..8692 + 1098 Protein_10 TonB-dependent receptor -
LRZ81_RS27670 (8760) 8760..9236 - 477 Protein_11 PAS domain-containing protein -
LRZ81_RS27675 (9289) 9289..9759 - 471 Protein_12 IS6 family transposase IS26 Transposase
LRZ81_RS27680 (9814) 9814..10518 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
LRZ81_RS27685 (12098) 12098..12332 + 235 Protein_14 type II toxin-antitoxin system RelE/ParE family toxin -
LRZ81_RS27690 (12460) 12460..12741 + 282 WP_001333089.1 hypothetical protein -
LRZ81_RS27695 (12864) 12864..13214 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
LRZ81_RS27700 (13217) 13217..14179 - 963 WP_000959884.1 plasmid segregation protein ParM -
LRZ81_RS27705 (14326) 14326..14619 + 294 WP_032146011.1 hypothetical protein -
LRZ81_RS27710 (14696) 14696..15379 + 684 WP_000085883.1 DNA methylase -
LRZ81_RS27715 (15380) 15380..15601 + 222 WP_001104881.1 hypothetical protein -
LRZ81_RS27720 (15615) 15615..16049 + 435 WP_000274503.1 DUF1380 family protein -
LRZ81_RS27725 (16100) 16100..16876 + 777 WP_001383963.1 hypothetical protein -
LRZ81_RS27730 (17294) 17294..17719 + 426 WP_001198928.1 antirestriction protein -
LRZ81_RS27735 (17766) 17766..18188 + 423 WP_000271762.1 DUF1380 family protein -
LRZ81_RS27740 (18185) 18185..18376 + 192 WP_001027493.1 hypothetical protein -
LRZ81_RS27745 (18690) 18690..20357 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
LRZ81_RS27750 (21086) 21086..21240 - 155 Protein_27 hypothetical protein -
LRZ81_RS27755 (21757) 21757..21987 + 231 WP_000218642.1 hypothetical protein -
LRZ81_RS27760 (22039) 22039..23400 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
LRZ81_RS27765 (23447) 23447..24010 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
LRZ81_RS27770 (24096) 24096..24557 - 462 Protein_31 hypothetical protein -
LRZ81_RS27775 (24859) 24859..25386 + 528 WP_000290834.1 single-stranded DNA-binding protein -
LRZ81_RS27780 (25444) 25444..25677 + 234 WP_000006003.1 DUF905 family protein -
LRZ81_RS27785 (25738) 25738..27706 + 1969 Protein_34 ParB/RepB/Spo0J family partition protein -
LRZ81_RS27790 (27775) 27775..28209 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
LRZ81_RS27795 (28206) 28206..28925 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- (28937) 28937..29161 + 225 NuclAT_0 - -
- (28937) 28937..29161 + 225 NuclAT_0 - -
- (28937) 28937..29161 + 225 NuclAT_0 - -
- (28937) 28937..29161 + 225 NuclAT_0 - -
LRZ81_RS27800 (29147) 29147..29296 + 150 Protein_37 plasmid maintenance protein Mok -
LRZ81_RS27805 (29238) 29238..29363 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
LRZ81_RS27810 (29682) 29682..29978 - 297 Protein_39 hypothetical protein -
LRZ81_RS27815 (30278) 30278..30574 + 297 WP_001272251.1 hypothetical protein -
LRZ81_RS27820 (30685) 30685..31506 + 822 WP_001234445.1 DUF932 domain-containing protein -
LRZ81_RS27825 (31803) 31803..32450 - 648 WP_015059008.1 hypothetical protein VF
LRZ81_RS27830 (32727) 32727..33110 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
LRZ81_RS27835 (33301) 33301..33987 + 687 WP_015059009.1 PAS domain-containing protein -
LRZ81_RS27840 (34081) 34081..34308 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
LRZ81_RS27845 (34342) 34342..34707 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
LRZ81_RS27850 (34722) 34722..35033 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
LRZ81_RS27855 (35055) 35055..35621 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
LRZ81_RS27860 (35608) 35608..36336 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
LRZ81_RS27865 (36336) 36336..37763 + 1428 WP_032297072.1 F-type conjugal transfer pilus assembly protein TraB -
LRZ81_RS27870 (37753) 37753..38343 + 591 WP_000002778.1 conjugal transfer pilus-stabilizing protein TraP -
LRZ81_RS27875 (38330) 38330..38527 + 198 WP_001324648.1 conjugal transfer protein TrbD -
LRZ81_RS27880 (38539) 38539..38790 + 252 WP_001038341.1 conjugal transfer protein TrbG -
LRZ81_RS27885 (38787) 38787..39302 + 516 WP_062955122.1 type IV conjugative transfer system lipoprotein TraV -
LRZ81_RS27890 (39437) 39437..39658 + 222 WP_001278692.1 conjugal transfer protein TraR -
LRZ81_RS27895 (39818) 39818..42445 + 2628 WP_015059012.1 type IV secretion system protein TraC -
LRZ81_RS27900 (42442) 42442..42828 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
LRZ81_RS27905 (42825) 42825..43457 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
LRZ81_RS27910 (43454) 43454..44446 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
LRZ81_RS27915 (44473) 44473..44781 + 309 WP_000412447.1 hypothetical protein -
LRZ81_RS27920 (44844) 44844..45365 + 522 WP_015059014.1 hypothetical protein -
LRZ81_RS27925 (45392) 45392..46030 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
LRZ81_RS27930 (46027) 46027..46398 + 372 WP_000056336.1 hypothetical protein -
LRZ81_RS27935 (46424) 46424..46846 + 423 WP_001229309.1 HNH endonuclease signature motif containing protein -
LRZ81_RS27940 (46843) 46843..48693 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LRZ81_RS27945 (48720) 48720..48977 + 258 WP_053913405.1 conjugal transfer protein TrbE -
LRZ81_RS27950 (48964) 48964..49713 + 750 WP_072354014.1 type-F conjugative transfer system pilin assembly protein TraF -
LRZ81_RS27955 (49874) 49874..50110 + 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
LRZ81_RS27960 (50097) 50097..50642 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LRZ81_RS27965 (50632) 50632..50946 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
LRZ81_RS27970 (50900) 50900..51292 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
LRZ81_RS27975 (51279) 51279..52652 + 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
LRZ81_RS27980 (52649) 52649..55465 + 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
LRZ81_RS27985 (55498) 55498..56019 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
LRZ81_RS27990 (56044) 56044..56775 + 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
LRZ81_RS27995 (56978) 56978..57715 + 738 WP_015059020.1 hypothetical protein -
LRZ81_RS28000 (57766) 57766..59982 + 2217 WP_059274178.1 type IV conjugative transfer system coupling protein TraD -
LRZ81_RS28005 (59982) 59982..65117 + 5136 WP_071177725.1 Multifunctional conjugation protein TraI Relaxase
LRZ81_RS28010 (65151) 65151..65855 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LRZ81_RS28015 (65921) 65921..66205 + 285 Protein_80 PAS domain-containing protein -
LRZ81_RS28020 (66269) 66269..66973 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LRZ81_RS28025 (67027) 67027..67354 - 328 Protein_82 class II aldolase/adducin family protein -
LRZ81_RS28030 (67347) 67347..68599 - 1253 Protein_83 four-carbon acid sugar kinase family protein -
LRZ81_RS28035 (68611) 68611..69511 - 901 Protein_84 NAD(P)-dependent oxidoreductase -
LRZ81_RS28040 (69773) 69773..70534 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
LRZ81_RS28045 (70555) 70555..71415 - 861 WP_002904004.1 Beta-lactamase SHV-2 ARG
LRZ81_RS28050 (71552) 71552..71620 + 69 Protein_87 IS6 family transposase -
LRZ81_RS28055 (71656) 71656..74620 - 2965 Protein_88 Tn3 family transposase TnpA_TnAs1 Transposase
LRZ81_RS28060 (74624) 74624..75184 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
LRZ81_RS28065 (75576) 75576..76193 + 618 Protein_90 replication protein -
LRZ81_RS28070 (76727) 76727..77005 + 279 WP_013213990.1 hypothetical protein -
LRZ81_RS28075 (77116) 77116..77541 + 426 WP_013213989.1 antirestriction protein -
LRZ81_RS28080 (77669) 77669..77824 + 156 WP_013213988.1 hypothetical protein -
LRZ81_RS28085 (77870) 77870..78166 + 297 WP_013213987.1 transcriptional regulator -
LRZ81_RS28090 (78270) 78270..79151 + 882 Protein_95 IS1182 family transposase ISKpn6 Transposase
LRZ81_RS28095 (79401) 79401..80282 - 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
LRZ81_RS28100 (80558) 80558..81538 - 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
LRZ81_RS28105 (81661) 81661..82122 - 462 Protein_98 Tn3 family transposase TnpR_Tn3 Transposase
LRZ81_RS28110 (82174) 82174..82878 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LRZ81_RS28115 (82943) 82943..84115 - 1173 Protein_100 transposase -
LRZ81_RS28120 (84190) 84190..84858 - 669 WP_001300294.1 putative signaling protein VF
LRZ81_RS28125 (84894) 84894..85130 - 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
LRZ81_RS28130 (85127) 85127..85489 - 363 WP_001277456.1 mercury resistance co-regulator MerD -
LRZ81_RS28135 (85507) 85507..87201 - 1695 WP_000105636.1 mercury(II) reductase -
LRZ81_RS28140 (87253) 87253..87675 - 423 WP_001340589.1 organomercurial transporter MerC -
LRZ81_RS28145 (87711) 87711..87986 - 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
LRZ81_RS28150 (88000) 88000..88350 - 351 WP_001294663.1 mercuric transport protein MerT -
LRZ81_RS28155 (88422) 88422..88856 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
LRZ81_RS28160 (88935) 88935..89940 + 1006 Protein_109 IS110 family transposase IS5075 Transposase
LRZ81_RS28165 (90220) 90220..90492 - 273 Protein_110 IS5 family transposase ISPan1 Transposase
LRZ81_RS28175 (91474) 91474..92496 - 1023 WP_000361404.1 helicase UvrD -
LRZ81_RS28180 (92481) 92481..94043 - 1563 WP_004206609.1 AAA family ATPase -
LRZ81_RS28185 (94117) 94117..94533 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
LRZ81_RS28190 (94530) 94530..94760 - 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin -
LRZ81_RS28195 (94717) 94717..95178 + 462 WP_014343465.1 hypothetical protein -
LRZ81_RS28200 (95339) 95339..96283 + 945 WP_011977810.1 hypothetical protein -
LRZ81_RS28205 (96320) 96320..96712 + 393 WP_011977811.1 hypothetical protein -
LRZ81_RS28210 (96770) 96770..97291 + 522 WP_013214008.1 hypothetical protein -
LRZ81_RS28215 (97337) 97337..97540 + 204 WP_011977813.1 hypothetical protein -
LRZ81_RS28220 (97570) 97570..98574 + 1005 WP_011977814.1 hypothetical protein -
LRZ81_RS28225 (98758) 98758..99537 + 780 WP_013214009.1 site-specific integrase -
LRZ81_RS28230 (99583) 99583..99840 - 258 WP_013214010.1 hypothetical protein -
LRZ81_RS28235 (99969) 99969..100082 - 114 WP_014343462.1 hypothetical protein -
LRZ81_RS28240 (100618) 100618..101484 + 867 WP_004118283.1 replication initiation protein -
LRZ81_RS28245 (102594) 102594..103799 + 1206 WP_011977818.1 AAA family ATPase -
LRZ81_RS28250 (103799) 103799..104773 + 975 WP_011977819.1 ParB family protein -
LRZ81_RS28255 (104855) 104855..106126 - 1272 WP_013214011.1 Y-family DNA polymerase -
LRZ81_RS28260 (106126) 106126..106557 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
LRZ81_RS28265 (106964) 106964..108451 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
LRZ81_RS28270 (108700) 108700..109671 + 972 WP_004152353.1 plasmid segregation protein ParM -
LRZ81_RS28275 (109674) 109674..110345 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
LRZ81_RS28280 (110408) 110408..110638 + 231 WP_001568040.1 hypothetical protein -
LRZ81_RS28285 (110834) 110834..111003 + 170 Protein_134 hypothetical protein -
LRZ81_RS28290 (111075) 111075..111776 + 702 WP_001568041.1 DNA methylase -
LRZ81_RS28295 (111776) 111776..111997 + 222 WP_001568042.1 hypothetical protein -
LRZ81_RS28300 (112007) 112007..112426 + 420 WP_001568043.1 DUF1380 domain-containing protein -
LRZ81_RS28305 (112480) 112480..113247 + 768 WP_013214013.1 hypothetical protein -
LRZ81_RS28310 (113928) 113928..114356 + 429 WP_001568045.1 antirestriction protein -
LRZ81_RS28315 (114399) 114399..114905 + 507 WP_013214014.1 antirestriction protein ArdA -
LRZ81_RS28320 (114948) 114948..115139 + 192 WP_001568047.1 hypothetical protein -
LRZ81_RS28325 (115327) 115327..115581 + 255 WP_011977779.1 DNA polymerase III subunit theta -
LRZ81_RS28330 (115616) 115616..115936 + 321 WP_001568049.1 hypothetical protein -
LRZ81_RS28335 (116616) 116616..116843 + 228 WP_001568050.1 hypothetical protein -
LRZ81_RS28340 (116935) 116935..117165 + 231 WP_001568051.1 hypothetical protein -
LRZ81_RS28345 (117217) 117217..118572 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
LRZ81_RS28350 (118620) 118620..119183 + 564 WP_014343514.1 methyltransferase -
LRZ81_RS28355 (120016) 120016..120558 + 543 WP_014343512.1 single-stranded DNA-binding protein -
LRZ81_RS28360 (120607) 120607..120855 + 249 WP_001568055.1 DUF905 domain-containing protein -
LRZ81_RS28365 (120925) 120925..122982 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
LRZ81_RS28370 (123027) 123027..123458 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
LRZ81_RS28375 (123455) 123455..124183 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
LRZ81_RS28380 (124180) 124180..124506 + 327 WP_013023807.1 hypothetical protein -
LRZ81_RS28385 (124562) 124562..124936 + 375 WP_014343510.1 hypothetical protein -
LRZ81_RS28390 (125106) 125106..125258 + 153 WP_004150508.1 DUF5431 family protein -
LRZ81_RS28395 (125203) 125203..125322 + 120 WP_159376494.1 type I toxin-antitoxin system Hok family toxin -
LRZ81_RS28400 (126015) 126015..126287 + 273 WP_040245921.1 hypothetical protein -
LRZ81_RS28405 (126284) 126284..126634 + 351 WP_040245917.1 hypothetical protein -
LRZ81_RS28410 (126649) 126649..126966 + 318 WP_014343505.1 hypothetical protein -
LRZ81_RS28415 (127807) 127807..128163 + 357 WP_014343501.1 hypothetical protein -
LRZ81_RS28420 (128224) 128224..128436 + 213 WP_014343500.1 hypothetical protein -
LRZ81_RS28425 (128447) 128447..128671 + 225 WP_014343499.1 hypothetical protein -
LRZ81_RS28430 (128752) 128752..129072 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
LRZ81_RS28435 (129062) 129062..129340 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
LRZ81_RS28440 (129344) 129344..129448 + 105 Protein_165 transcriptional regulator -
LRZ81_RS28445 (130277) 130277..131098 + 822 WP_004152492.1 DUF932 domain-containing protein -
LRZ81_RS28450 (131131) 131131..131460 + 330 WP_013214015.1 DUF5983 family protein -
LRZ81_RS28455 (131493) 131493..131978 - 486 WP_014343495.1 hypothetical protein VF
LRZ81_RS28460 (132369) 132369..132785 + 417 WP_014343494.1 conjugal transfer relaxosome DNA-binding protein TraM -
LRZ81_RS28465 (132985) 132985..133722 + 738 WP_154244330.1 conjugal transfer protein TrbJ -
LRZ81_RS28470 (133837) 133837..134043 + 207 WP_171773970.1 TraY domain-containing protein -
LRZ81_RS28475 (134105) 134105..134473 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
LRZ81_RS28480 (134487) 134487..134792 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
LRZ81_RS28485 (134812) 134812..135177 + 366 Protein_174 type IV conjugative transfer system protein TraE -
LRZ81_RS28490 (135232) 135232..135936 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LRZ81_RS28495 (135961) 135961..136161 + 201 WP_072354025.1 hypothetical protein -
LRZ81_RS28500 (136181) 136181..136927 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
LRZ81_RS28505 (136982) 136982..137542 + 561 WP_000139328.1 fertility inhibition protein FinO -
LRZ81_RS28510 (137674) 137674..137874 + 201 WP_015059022.1 hypothetical protein -
LRZ81_RS28515 (138260) 138260..138859 + 600 WP_032083981.1 PIN domain-containing protein -
LRZ81_RS28520 (138921) 138921..139253 + 333 WP_152916585.1 hypothetical protein -
- (139454) 139454..139513 - 60 NuclAT_1 - Antitoxin Detail
- (139454) 139454..139513 - 60 NuclAT_1 - Antitoxin Detail
- (139454) 139454..139513 - 60 NuclAT_1 - Antitoxin Detail
- (139454) 139454..139513 - 60 NuclAT_1 - Antitoxin Detail
LRZ81_RS28525 (139558) 139558..139707 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
LRZ81_RS28530 (139991) 139991..140239 + 249 WP_000083837.1 replication regulatory protein RepA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance