MGE detailed information
MGE type: Conjugative plasmid MGE length: 126075 bp
Accession: NZ_CP086619 Location: 1..126075 Organism: Escherichia coli strain RIVM_C039227 Replicon: plasmid pRIVM_C039227_1
Accession: NZ_CP086619 Location: 1..126075 Organism: Escherichia coli strain RIVM_C039227 Replicon: plasmid pRIVM_C039227_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LN355_RS25215 () | 1..861 | + | 861 | WP_000704523.1 | putative protein YcjY | VF |
| LN355_RS25220 () | 964..1524 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| LN355_RS25225 () | 1653..1865 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| LN355_RS25230 () | 2110..2253 | + | 144 | Protein_3 | endonuclease | - |
| LN355_RS25235 () | 2343..2768 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| LN355_RS25240 () | 2765..3115 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| LN355_RS25245 () | 3146..4759 | + | 1614 | WP_135118410.1 | IS66 family transposase ISEc23 | Transposase |
| LN355_RS25250 () | 4791..5111 | + | 321 | Protein_7 | thermonuclease family protein | - |
| LN355_RS25255 () | 5157..5366 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| LN355_RS25260 () | 5404..5994 | + | 591 | WP_000766805.1 | DUF2726 domain-containing protein | - |
| LN355_RS25265 () | 6234..6494 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| LN355_RS25270 () | 6719..6793 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| LN355_RS25275 () | 6786..7643 | + | 858 | WP_000130647.1 | incFII family plasmid replication initiator RepA | - |
| LN355_RS25280 () | 8582..9235 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| LN355_RS25285 () | 9328..9585 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LN355_RS25290 () | 9518..9919 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LN355_RS25295 () | 10168..10583 | + | 416 | Protein_16 | IS1-like element IS1B family transposase | - |
| LN355_RS25300 () | 10619..11164 | - | 546 | Protein_17 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LN355_RS25305 () | 11230..11934 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN355_RS25310 () | 12001..12931 | - | 931 | Protein_19 | IS3 family transposase | - |
| LN355_RS25315 () | 13051..13971 | - | 921 | Protein_20 | IS4 family transposase IS4 | Transposase |
| LN355_RS25320 () | 14110..14904 | + | 795 | WP_063625815.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
| LN355_RS25325 () | 14916..15767 | + | 852 | WP_032248272.1 | pantoate--beta-alanine ligase | - |
| LN355_RS25330 () | 15912..15986 | - | 75 | Protein_23 | hypothetical protein | - |
| LN355_RS25335 () | 16065..16305 | + | 241 | Protein_24 | polysaccharide deacetylase family protein | - |
| LN355_RS25340 () | 16309..16689 | - | 381 | WP_000621515.1 | aspartate 1-decarboxylase | - |
| LN355_RS25345 () | 16963..17094 | + | 132 | Protein_26 | Rpn family recombination-promoting nuclease/putative transposase | - |
| LN355_RS25350 () | 17292..18686 | + | 1395 | WP_050488426.1 | MFS transporter | - |
| LN355_RS25355 () | 18792..19823 | + | 1032 | WP_000194408.1 | LacI family DNA-binding transcriptional regulator | - |
| LN355_RS25360 () | 19798..20817 | + | 1020 | WP_077758491.1 | nucleoside hydrolase | - |
| LN355_RS25365 () | 20934..21638 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN355_RS25370 () | 21786..21890 | + | 105 | Protein_31 | integrase core domain-containing protein | - |
| LN355_RS25375 () | 22040..23038 | + | 999 | WP_004175650.1 | ABC transporter substrate-binding protein | - |
| LN355_RS25380 () | 23038..24075 | + | 1038 | WP_032248242.1 | Hemin transport system permease protein HmuU | VF |
| LN355_RS25385 () | 24075..24836 | + | 762 | WP_000020504.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| LN355_RS25390 () | 24893..26080 | + | 1188 | WP_162753250.1 | MFS transporter | - |
| LN355_RS25395 () | 26176..27156 | + | 981 | WP_063624983.1 | IS5 family transposase ISKpn26 | Transposase |
| LN355_RS25400 () | 27306..27938 | - | 633 | Protein_37 | histidine-type phosphatase | - |
| LN355_RS25405 () | 28060..28545 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| LN355_RS25410 () | 28570..29055 | - | 486 | WP_001554949.1 | TlpA disulfide reductase family protein | - |
| LN355_RS25415 () | 29042..29737 | - | 696 | WP_063624982.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| LN355_RS25420 () | 29742..30872 | - | 1131 | WP_000729219.1 | ABC transporter permease | - |
| LN355_RS25425 () | 30862..32145 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| LN355_RS25430 () | 32148..33527 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| LN355_RS25435 () | 33631..34158 | - | 528 | WP_000178050.1 | iron transporter | - |
| LN355_RS25440 () | 34199..36085 | - | 1887 | WP_192514405.1 | FTR1 family protein | - |
| LN355_RS25445 () | 36432..37193 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| LN355_RS25450 () | 37430..37936 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| LN355_RS25455 () | 37926..38096 | - | 171 | Protein_48 | DsbA family protein | - |
| LN355_RS25460 () | 38234..38347 | - | 114 | Protein_49 | IS6 family transposase | - |
| LN355_RS25465 () | 38547..39244 | + | 698 | WP_151884388.1 | IS1 family transposase IS1X2 | Transposase |
| LN355_RS25470 () | 39259..39477 | + | 219 | Protein_51 | IS4 family transposase | - |
| LN355_RS25475 () | 39527..40231 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN355_RS25480 () | 40290..41039 | - | 750 | Protein_53 | IS91 family transposase ISAzo26 | Transposase |
| LN355_RS25485 () | 41197..41670 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| LN355_RS25490 () | 41801..42589 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| LN355_RS25495 () | 42795..43142 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| LN355_RS25500 () | 43136..43975 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| LN355_RS25505 () | 44103..44306 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| LN355_RS25510 () | 44462..45667 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| LN355_RS25515 () | 45678..45983 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| LN355_RS25520 () | 46027..46092 | + | 66 | Protein_61 | EAL domain-containing protein | - |
| LN355_RS25525 () | 46210..46974 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| LN355_RS25530 () | 47467..48051 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| LN355_RS25535 () | 48051..49289 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| LN355_RS25540 () | 49286..50191 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| LN355_RS25545 () | 50313..51017 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN355_RS25550 () | 51081..51761 | - | 681 | Protein_67 | carbohydrate ABC transporter permease | - |
| LN355_RS25555 () | 51751..52629 | - | 879 | WP_162753243.1 | sugar ABC transporter permease | - |
| LN355_RS25560 () | 52760..53326 | - | 567 | Protein_69 | zinc-binding dehydrogenase | - |
| LN355_RS25565 () | 53679..54569 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| LN355_RS25570 () | 54594..54974 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| LN355_RS25575 () | 55007..55972 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| LN355_RS25580 () | 56018..56770 | - | 753 | WP_001403368.1 | IclR family transcriptional regulator | - |
| LN355_RS25585 () | 57375..57659 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| LN355_RS25590 () | 57659..57934 | + | 276 | WP_000421273.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| LN355_RS25595 () | 58040..58243 | + | 204 | Protein_76 | hypothetical protein | - |
| LN355_RS25600 () | 58368..58496 | - | 129 | Protein_77 | IS481 family transposase | - |
| LN355_RS25605 () | 58529..59698 | - | 1170 | WP_001403369.1 | hypothetical protein | - |
| LN355_RS25610 () | 60230..60498 | + | 269 | Protein_79 | type II toxin-antitoxin system ParD family antitoxin | - |
| LN355_RS25615 () | 60485..60775 | + | 291 | Protein_80 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LN355_RS25620 () | 60842..61024 | + | 183 | WP_042344623.1 | hypothetical protein | - |
| LN355_RS25625 () | 61145..61885 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| LN355_RS25630 () | 62128..63105 | - | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| LN355_RS25635 () | 64280..64921 | - | 642 | WP_000990667.1 | hypothetical protein | - |
| LN355_RS25640 () | 67243..67461 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| LN355_RS25645 () | 67463..67768 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| LN355_RS25650 () | 67769..68578 | + | 810 | WP_000016979.1 | site-specific integrase | - |
| LN355_RS25655 () | 68716..68991 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| LN355_RS25660 () | 68985..69629 | - | 645 | WP_000633911.1 | AAA family ATPase | - |
| LN355_RS25665 () | 69858..70829 | + | 972 | WP_001103694.1 | plasmid segregation protein ParM | - |
| LN355_RS25670 () | 70834..71226 | + | 393 | WP_000340835.1 | plasmid partitioning/stability family protein | - |
| LN355_RS25675 () | 71231..71482 | - | 252 | Protein_92 | DUF4113 domain-containing protein | - |
| LN355_RS25680 () | 71544..72341 | - | 798 | WP_000544830.1 | IS21 family transposase IS21 | Transposase |
| LN355_RS25685 () | 72341..73513 | - | 1173 | WP_000952372.1 | IS21 family transposase IS21 | Transposase |
| LN355_RS25690 () | 73615..74636 | - | 1022 | Protein_95 | translesion error-prone DNA polymerase V subunit UmuC | - |
| LN355_RS25695 () | 74636..75073 | - | 438 | WP_000109079.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| LN355_RS25700 () | 75070..75318 | - | 249 | WP_000619112.1 | DinI-like family protein | - |
| LN355_RS25705 () | 75453..75971 | + | 519 | WP_000115885.1 | hypothetical protein | VF |
| LN355_RS25710 () | 75990..77210 | + | 1221 | WP_000343766.1 | ISL3 family transposase ISEc53 | Transposase |
| LN355_RS25715 () | 77629..78531 | + | 903 | WP_001310012.1 | DUF1281 domain-containing protein | - |
| LN355_RS25720 () | 78528..78839 | + | 312 | WP_001310011.1 | hypothetical protein | - |
| LN355_RS25725 () | 78915..79598 | + | 684 | WP_000086169.1 | DNA methylase | - |
| LN355_RS25730 () | 79599..79820 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| LN355_RS25735 () | 79750..80268 | + | 519 | WP_223364201.1 | DUF1380 family protein | - |
| LN355_RS25740 () | 80313..81083 | + | 771 | WP_001004562.1 | hypothetical protein | - |
| LN355_RS25745 () | 81499..81924 | + | 426 | WP_001198903.1 | antirestriction protein | - |
| LN355_RS25750 () | 81971..82393 | + | 423 | WP_000271708.1 | DUF1380 family protein | - |
| LN355_RS25755 () | 82390..82581 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| LN355_RS25760 () | 83544..83774 | + | 231 | WP_000155844.1 | hypothetical protein | - |
| LN355_RS25765 () | 83826..85187 | + | 1362 | WP_000170667.1 | DUF3560 domain-containing protein | - |
| LN355_RS25770 () | 85234..85797 | + | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| LN355_RS25775 () | 85797..86027 | + | 231 | WP_001333093.1 | hypothetical protein | - |
| LN355_RS25780 () | 85949..86197 | + | 249 | WP_071606928.1 | hypothetical protein | - |
| LN355_RS25785 () | 86667..87194 | + | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| LN355_RS25790 () | 87250..87483 | + | 234 | WP_000006018.1 | DUF905 domain-containing protein | - |
| LN355_RS25795 () | 87542..89500 | + | 1959 | WP_032152921.1 | ParB/RepB/Spo0J family partition protein | - |
| LN355_RS25800 () | 89555..89989 | + | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| LN355_RS25805 () | 89986..90748 | + | 763 | Protein_118 | plasmid SOS inhibition protein A | - |
| LN355_RS25810 () | 90717..90905 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 90717..90941 | + | 225 | NuclAT_0 | - | - |
| - () | 90717..90941 | + | 225 | NuclAT_0 | - | - |
| - () | 90717..90941 | + | 225 | NuclAT_0 | - | - |
| - () | 90717..90941 | + | 225 | NuclAT_0 | - | - |
| - | 90874..90939 | - | 66 | - | - | Antitoxin Detail |
| LN355_RS25815 () | 90927..91076 | + | 150 | Protein_120 | plasmid maintenance protein Mok | - |
| LN355_RS25820 () | 91018..91143 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| LN355_RS25825 () | 91363..91593 | + | 231 | WP_071587244.1 | hypothetical protein | - |
| LN355_RS25830 () | 91591..91764 | - | 174 | Protein_123 | hypothetical protein | - |
| LN355_RS25835 () | 92062..92349 | + | 288 | WP_000107537.1 | hypothetical protein | - |
| LN355_RS25840 () | 92470..93291 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| LN355_RS25845 () | 93588..94235 | - | 648 | WP_124760006.1 | hypothetical protein | VF |
| LN355_RS25850 () | 94521..94904 | + | 384 | WP_001151564.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LN355_RS25855 () | 95098..95784 | + | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| LN355_RS25860 () | 95878..96105 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| LN355_RS25865 () | 96139..96501 | + | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| LN355_RS25870 () | 96506..96817 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| LN355_RS25875 () | 96839..97405 | + | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| LN355_RS25880 () | 97392..98120 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| LN355_RS25885 () | 98120..99547 | + | 1428 | WP_000146638.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| LN355_RS25890 () | 99537..100121 | + | 585 | WP_000002795.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| LN355_RS25895 () | 100108..100428 | + | 321 | WP_001057302.1 | conjugal transfer protein TrbD | - |
| LN355_RS25900 () | 100421..100672 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| LN355_RS25905 () | 100669..101184 | + | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| LN355_RS25910 () | 101319..101540 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| LN355_RS25915 () | 101700..104326 | + | 2627 | Protein_140 | type IV secretion system protein TraC | - |
| LN355_RS25920 () | 104323..104709 | + | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| LN355_RS25925 () | 104706..105338 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| LN355_RS25930 () | 105335..106327 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| LN355_RS25935 () | 106357..106662 | + | 306 | WP_000224411.1 | hypothetical protein | - |
| LN355_RS25940 () | 106671..107309 | + | 639 | WP_001080257.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| LN355_RS25945 () | 107306..109114 | + | 1809 | WP_024221016.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LN355_RS25950 () | 109141..109398 | + | 258 | WP_000864320.1 | conjugal transfer protein TrbE | - |
| LN355_RS25955 () | 109391..110134 | + | 744 | WP_001749618.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LN355_RS25960 () | 110150..110488 | + | 339 | WP_001287905.1 | conjugal transfer protein TrbA | - |
| LN355_RS25965 () | 110615..110899 | + | 285 | WP_001448202.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LN355_RS25970 () | 110886..111431 | + | 546 | WP_000059824.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LN355_RS25975 () | 111361..111702 | + | 342 | WP_001448115.1 | P-type conjugative transfer protein TrbJ | - |
| LN355_RS25980 () | 111683..112075 | + | 393 | WP_000660703.1 | F-type conjugal transfer protein TrbF | - |
| LN355_RS25985 () | 112062..113435 | + | 1374 | WP_001137364.1 | conjugal transfer pilus assembly protein TraH | - |
| LN355_RS25990 () | 113432..116251 | + | 2820 | WP_001007057.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LN355_RS25995 () | 116270..116767 | + | 498 | WP_000605861.1 | hypothetical protein | - |
| LN355_RS26000 () | 116799..117530 | + | 732 | WP_024221017.1 | conjugal transfer complement resistance protein TraT | - |
| LN355_RS26005 () | 117783..119981 | + | 2199 | WP_032302075.1 | type IV conjugative transfer system coupling protein TraD | - |
| LN355_RS26010 () | 119981..125251 | + | 5271 | WP_048967012.1 | Multifunctional conjugation protein TraI | Relaxase |
| LN355_RS26015 () | 125271..126017 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|