NZ_CP0820251..130597

MGE detailed information

MGE type: Mobilizable plasmid        MGE length: 130597 bp
Accession: NZ_CP082025        Location: 1..130597         Organism: Klebsiella pneumoniae strain KP18-2073       Replicon: plasmid pKP18-2073-KPC2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6166_RS27840 (592) 592..1332 - 741 Protein_1 hypothetical protein -
K6166_RS27845 (1385) 1385..2089 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS27850 (2159) 2159..2350 + 192 Protein_3 IS1380 family transposase -
K6166_RS27855 (2600) 2600..3475 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
K6166_RS27860 (3510) 3510..4478 + 969 WP_222666139.1 IS5 family transposase IS903B Transposase
K6166_RS27865 (4535) 4535..5632 + 1098 Protein_6 TonB-dependent receptor -
K6166_RS27870 (5700) 5700..6176 - 477 Protein_7 PAS domain-containing protein -
K6166_RS27875 (6229) 6229..6933 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS27880 (7319) 7319..7735 + 417 WP_014839980.1 Glutathione transferase FosA ARG
K6166_RS27885 (7740) 7740..8258 - 519 WP_014839979.1 FidL-like protein -
K6166_RS27890 (8324) 8324..9028 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS27895 (9414) 9414..9830 + 417 WP_014839980.1 Glutathione transferase FosA ARG
K6166_RS27900 (9835) 9835..10353 - 519 WP_014839979.1 FidL-like protein -
K6166_RS27905 (10419) 10419..11123 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS27910 (11579) 11579..12169 - 591 Protein_15 IS91 family transposase ISSbo1 Transposase
K6166_RS27915 (12234) 12234..12938 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS27920 (12989) 12989..13606 - 618 Protein_17 IS91 family transposase ISSbo1 Transposase
K6166_RS27925 (13616) 13616..13804 - 189 WP_000957857.1 hypothetical protein -
K6166_RS27930 (13896) 13896..14432 + 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
K6166_RS27935 (14615) 14615..15475 + 861 WP_000027057.1 Beta-lactamase TEM ARG
K6166_RS27940 (15645) 15645..16400 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
K6166_RS27945 (16481) 16481..16795 - 315 Protein_22 hypothetical protein -
K6166_RS27950 (16850) 16850..17554 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
K6166_RS27955 (17620) 17620..17685 + 66 Protein_24 IS1 family transposase -
K6166_RS27960 (19134) 19134..19368 + 235 Protein_25 type II toxin-antitoxin system RelE/ParE family toxin -
K6166_RS27965 (19496) 19496..19777 + 282 WP_001333089.1 hypothetical protein -
K6166_RS27970 (19900) 19900..20250 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
K6166_RS27975 (20253) 20253..21215 - 963 WP_000959884.1 plasmid segregation protein ParM -
K6166_RS27980 (21362) 21362..21655 + 294 WP_032146011.1 hypothetical protein -
K6166_RS27985 (21732) 21732..22415 + 684 WP_000085883.1 DNA methylase -
K6166_RS27990 (22416) 22416..22637 + 222 WP_001104881.1 hypothetical protein -
K6166_RS27995 (22651) 22651..23085 + 435 WP_000274503.1 DUF1380 family protein -
K6166_RS28000 (23136) 23136..23912 + 777 WP_001383963.1 hypothetical protein -
K6166_RS28005 (24330) 24330..24755 + 426 WP_001198928.1 antirestriction protein -
K6166_RS28010 (24802) 24802..25224 + 423 WP_000271762.1 DUF1380 family protein -
K6166_RS28015 (25221) 25221..25412 + 192 WP_001027493.1 hypothetical protein -
K6166_RS28020 (25726) 25726..27393 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
K6166_RS30210 (28122) 28122..28276 - 155 Protein_38 hypothetical protein -
K6166_RS28025 (28793) 28793..29023 + 231 WP_000218642.1 hypothetical protein -
K6166_RS28030 (29075) 29075..30436 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
K6166_RS28035 (30483) 30483..31046 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
K6166_RS30215 (31132) 31132..31593 - 462 Protein_42 hypothetical protein -
K6166_RS28040 (31895) 31895..32422 + 528 WP_000290834.1 single-stranded DNA-binding protein -
K6166_RS28045 (32480) 32480..32713 + 234 WP_000006003.1 DUF905 family protein -
K6166_RS28050 (32774) 32774..34797 + 2024 Protein_45 ParB/RepB/Spo0J family partition protein -
K6166_RS28055 (34866) 34866..35300 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
K6166_RS28060 (35297) 35297..36016 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- (36028) 36028..36252 + 225 NuclAT_0 - -
- (36028) 36028..36252 + 225 NuclAT_0 - -
- (36028) 36028..36252 + 225 NuclAT_0 - -
- (36028) 36028..36252 + 225 NuclAT_0 - -
K6166_RS30220 (36238) 36238..36387 + 150 Protein_48 plasmid maintenance protein Mok -
K6166_RS28065 (36329) 36329..36454 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
K6166_RS28070 (36773) 36773..37069 - 297 Protein_50 hypothetical protein -
K6166_RS28075 (37369) 37369..37665 + 297 WP_001272251.1 hypothetical protein -
K6166_RS28080 (37776) 37776..38597 + 822 WP_001234445.1 DUF932 domain-containing protein -
K6166_RS28085 (38894) 38894..39541 - 648 WP_015059008.1 hypothetical protein VF
K6166_RS28090 (39818) 39818..40201 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
K6166_RS28095 (40392) 40392..41078 + 687 WP_015059009.1 PAS domain-containing protein -
K6166_RS28100 (41172) 41172..41399 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
K6166_RS28105 (41433) 41433..41798 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
K6166_RS28110 (41813) 41813..42124 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
K6166_RS28115 (42146) 42146..42712 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
K6166_RS28120 (42699) 42699..43427 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
K6166_RS28125 (43427) 43427..43630 + 204 Protein_61 IS6 family transposase IS15 Transposase
K6166_RS28130 (43696) 43696..44400 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS28135 (44455) 44455..44790 - 336 Protein_63 class II aldolase/adducin family protein -
K6166_RS28140 (44783) 44783..46035 - 1253 Protein_64 four-carbon acid sugar kinase family protein -
K6166_RS28145 (46047) 46047..46949 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
K6166_RS28150 (47211) 47211..47972 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
K6166_RS28155 (47993) 47993..48853 - 861 WP_004176269.1 Beta-lactamase SHV-1 ARG
K6166_RS28160 (48990) 48990..49058 + 69 Protein_68 IS6 family transposase -
K6166_RS28165 (49094) 49094..50992 - 1899 Protein_69 Tn3 family transposase TnpA_TnAs1 Transposase
K6166_RS28170 (51058) 51058..51762 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS28175 (51814) 51814..52275 + 462 Protein_71 Tn3 family transposase TnpR_Tn3 Transposase
K6166_RS28180 (52398) 52398..53378 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
K6166_RS28185 (53654) 53654..54535 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
K6166_RS28190 (54785) 54785..55666 - 882 Protein_74 IS1182 family transposase ISKpn6 Transposase
K6166_RS28195 (55770) 55770..56066 - 297 WP_013213987.1 transcriptional regulator -
K6166_RS28200 (56112) 56112..56267 - 156 WP_013213988.1 hypothetical protein -
K6166_RS28205 (56395) 56395..56820 - 426 WP_013213989.1 antirestriction protein -
K6166_RS28210 (56931) 56931..57209 - 279 WP_013213990.1 hypothetical protein -
K6166_RS28215 (57743) 57743..58360 - 618 Protein_79 replication protein -
K6166_RS28220 (58752) 58752..59312 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
K6166_RS28225 (59316) 59316..60389 + 1074 Protein_81 Tn3 family transposase TnpA_TnAs1 Transposase
K6166_RS28230 (60442) 60442..61146 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS28235 (61211) 61211..62383 - 1173 Protein_83 transposase -
K6166_RS28240 (62458) 62458..63126 - 669 WP_001300294.1 putative signaling protein VF
K6166_RS28245 (63162) 63162..63398 - 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
K6166_RS28250 (63395) 63395..63757 - 363 WP_001277456.1 mercury resistance co-regulator MerD -
K6166_RS28255 (63775) 63775..65469 - 1695 WP_000105636.1 mercury(II) reductase -
K6166_RS28260 (65521) 65521..65943 - 423 WP_001340589.1 organomercurial transporter MerC -
K6166_RS28265 (65979) 65979..66254 - 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
K6166_RS28270 (66268) 66268..66618 - 351 WP_001294663.1 mercuric transport protein MerT -
K6166_RS28275 (66690) 66690..67124 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
K6166_RS28280 (67203) 67203..68207 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
K6166_RS28285 (68487) 68487..68759 - 273 Protein_93 transposase -
K6166_RS28290 (69231) 69231..69232 - 2 WP_024269734.1 IS1 family transposase ISKpn14 Transposase
K6166_RS28295 (69740) 69740..70762 - 1023 WP_000361404.1 helicase UvrD -
K6166_RS28300 (70747) 70747..72309 - 1563 WP_004206609.1 AAA family ATPase -
K6166_RS28305 (72383) 72383..72799 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
K6166_RS28310 (72796) 72796..73026 - 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
K6166_RS28315 (72983) 72983..73444 + 462 WP_014343465.1 hypothetical protein -
K6166_RS28320 (73605) 73605..74549 + 945 WP_011977810.1 hypothetical protein -
K6166_RS28325 (74586) 74586..74978 + 393 WP_011977811.1 hypothetical protein -
K6166_RS28330 (75036) 75036..75557 + 522 WP_013214008.1 hypothetical protein -
K6166_RS28335 (75603) 75603..75806 + 204 WP_011977813.1 hypothetical protein -
K6166_RS28340 (75836) 75836..76108 + 273 Protein_104 IS6 family transposase IS15 Transposase
K6166_RS28345 (76171) 76171..76875 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS28350 (76941) 76941..77486 + 546 Protein_106 Tn3 family transposase TnpA_Tn3 Transposase
K6166_RS28355 (77522) 77522..77937 - 416 Protein_107 IS1-like element IS1B family transposase -
K6166_RS28360 (78186) 78186..78587 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
K6166_RS28365 (78520) 78520..78777 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
K6166_RS28370 (78870) 78870..79523 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
K6166_RS28375 (80462) 80462..81319 - 858 WP_142295464.1 incFII family plasmid replication initiator RepA -
K6166_RS30230 (81338) 81338..81516 - 179 Protein_112 protein CopA/IncA -
K6166_RS28385 (81631) 81631..81879 - 249 WP_000083837.1 replication regulatory protein RepA -
K6166_RS28390 (82163) 82163..82312 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (82357) 82357..82416 + 60 NuclAT_1 - Antitoxin Detail
- (82357) 82357..82416 + 60 NuclAT_1 - Antitoxin Detail
- (82357) 82357..82416 + 60 NuclAT_1 - Antitoxin Detail
- (82357) 82357..82416 + 60 NuclAT_1 - Antitoxin Detail
K6166_RS28395 (82617) 82617..82949 - 333 WP_152916585.1 hypothetical protein -
K6166_RS28400 (83011) 83011..83610 - 600 WP_032083981.1 PIN domain-containing protein -
K6166_RS28405 (83996) 83996..84196 - 201 WP_015059022.1 hypothetical protein -
K6166_RS28410 (84328) 84328..84888 - 561 WP_000139328.1 fertility inhibition protein FinO -
K6166_RS28415 (84943) 84943..85689 - 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
K6166_RS28420 (85709) 85709..85909 - 201 WP_072354025.1 hypothetical protein -
K6166_RS28425 (85934) 85934..86638 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS28430 (86691) 86691..86756 + 66 Protein_122 helix-turn-helix domain-containing protein -
K6166_RS28435 (86759) 86759..89725 + 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
K6166_RS28440 (89804) 89804..90808 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
K6166_RS30235 (91080) 91080..91166 - 87 Protein_125 Arm DNA-binding domain-containing protein -
K6166_RS28450 (91288) 91288..91512 - 225 WP_000743213.1 hypothetical protein -
K6166_RS28455 (91509) 91509..92246 - 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
K6166_RS28460 (92732) 92732..92872 - 141 WP_001044210.1 hypothetical protein -
K6166_RS28465 (92878) 92878..93582 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS28470 (94051) 94051..94614 - 564 WP_155082050.1 hypothetical protein -
K6166_RS28475 (94736) 94736..95278 - 543 WP_077273850.1 restriction endonuclease -
K6166_RS28480 (95260) 95260..96240 - 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
K6166_RS28485 (96309) 96309..96701 + 393 Protein_133 3'-5' exonuclease -
K6166_RS28490 (96754) 96754..97149 + 396 WP_015493087.1 hypothetical protein -
K6166_RS28495 (97146) 97146..97757 + 612 WP_015493086.1 DUF2913 family protein -
K6166_RS28500 (97754) 97754..98704 - 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
K6166_RS28505 (99033) 99033..99737 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6166_RS30240 (100315) 100315..100419 - 105 Protein_138 transcriptional regulator -
K6166_RS28510 (100423) 100423..100701 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
K6166_RS28515 (100691) 100691..101011 - 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
K6166_RS28520 (101092) 101092..101316 - 225 WP_014343499.1 hypothetical protein -
K6166_RS28525 (101327) 101327..101539 - 213 WP_014343500.1 hypothetical protein -
K6166_RS28530 (101600) 101600..101956 - 357 WP_014343501.1 hypothetical protein -
K6166_RS28535 (102797) 102797..103114 - 318 WP_014343505.1 hypothetical protein -
K6166_RS28540 (103129) 103129..103479 - 351 WP_040245917.1 hypothetical protein -
K6166_RS28545 (103476) 103476..103748 - 273 WP_040245921.1 hypothetical protein -
K6166_RS28550 (104441) 104441..104557 - 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
K6166_RS30245 (104508) 104508..104657 - 150 Protein_148 DUF5431 family protein -
K6166_RS28555 (104827) 104827..105201 - 375 WP_014343510.1 hypothetical protein -
K6166_RS28560 (105257) 105257..105583 - 327 WP_013023807.1 hypothetical protein -
K6166_RS28565 (105580) 105580..106308 - 729 WP_001568058.1 plasmid SOS inhibition protein A -
K6166_RS28570 (106305) 106305..106736 - 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
K6166_RS28575 (106781) 106781..108838 - 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
K6166_RS28580 (108908) 108908..109156 - 249 WP_001568055.1 DUF905 domain-containing protein -
K6166_RS28585 (109205) 109205..109747 - 543 WP_014343512.1 single-stranded DNA-binding protein -
K6166_RS28590 (110580) 110580..111143 - 564 WP_014343514.1 methyltransferase -
K6166_RS28595 (111191) 111191..112546 - 1356 WP_222690602.1 DUF3560 domain-containing protein -
K6166_RS28600 (112598) 112598..112828 - 231 WP_001568051.1 hypothetical protein -
K6166_RS28605 (112920) 112920..113147 - 228 WP_001568050.1 hypothetical protein -
K6166_RS28610 (113827) 113827..114147 - 321 WP_001568049.1 hypothetical protein -
K6166_RS28615 (114182) 114182..114436 - 255 WP_011977779.1 DNA polymerase III subunit theta -
K6166_RS28620 (114624) 114624..114815 - 192 WP_001568047.1 hypothetical protein -
K6166_RS28625 (114858) 114858..115364 - 507 WP_013214014.1 antirestriction protein ArdA -
K6166_RS28630 (115407) 115407..115835 - 429 WP_001568045.1 antirestriction protein -
K6166_RS28635 (116516) 116516..117283 - 768 WP_013214013.1 hypothetical protein -
K6166_RS28640 (117337) 117337..117756 - 420 WP_001568043.1 DUF1380 domain-containing protein -
K6166_RS28645 (117766) 117766..117987 - 222 WP_001568042.1 hypothetical protein -
K6166_RS28650 (117987) 117987..118688 - 702 WP_151488309.1 DNA methylase -
K6166_RS30250 (118760) 118760..118929 - 170 Protein_169 hypothetical protein -
K6166_RS28655 (119125) 119125..119355 - 231 WP_001568040.1 hypothetical protein -
K6166_RS28660 (119418) 119418..120089 - 672 WP_013214012.1 plasmid partitioning/stability family protein -
K6166_RS28665 (120092) 120092..121063 - 972 WP_004152353.1 plasmid segregation protein ParM -
K6166_RS28670 (121312) 121312..122799 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
K6166_RS28675 (123206) 123206..123637 + 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
K6166_RS28680 (123637) 123637..124908 + 1272 WP_013214011.1 Y-family DNA polymerase -
K6166_RS28685 (124990) 124990..125964 - 975 WP_011977819.1 ParB family protein -
K6166_RS28690 (125964) 125964..127169 - 1206 WP_011977818.1 AAA family ATPase -
K6166_RS28695 (128279) 128279..129145 - 867 WP_004118283.1 replication initiation protein -
K6166_RS28700 (129681) 129681..129794 + 114 WP_014343462.1 hypothetical protein -
K6166_RS28705 (129923) 129923..130180 + 258 WP_013214010.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance