NZ_CP0820201..135837

MGE detailed information

MGE type: Mobilizable plasmid        MGE length: 135837 bp
Accession: NZ_CP082020        Location: 1..135837         Organism: Klebsiella pneumoniae strain KP18-2050       Replicon: plasmid pKP18-2050-KPC2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6159_RS27840 (1) 1..858 + 858 WP_142295464.1 incFII family plasmid replication initiator RepA -
K6159_RS27845 (1797) 1797..2450 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
K6159_RS27850 (2543) 2543..2800 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
K6159_RS27855 (2733) 2733..3134 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
K6159_RS27860 (3383) 3383..3798 + 416 Protein_4 IS1 family transposase IS1R Transposase
K6159_RS27865 (3834) 3834..4379 - 546 Protein_5 Tn3 family transposase TnpA_Tn3 Transposase
K6159_RS27870 (4445) 4445..5149 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS27875 (5219) 5219..5410 + 192 Protein_7 IS1380 family transposase -
K6159_RS27880 (5660) 5660..6535 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
K6159_RS27885 (6570) 6570..7538 + 969 WP_222666139.1 IS5 family transposase IS903B Transposase
K6159_RS27890 (7595) 7595..8692 + 1098 Protein_10 TonB-dependent receptor -
K6159_RS27895 (8760) 8760..9236 - 477 Protein_11 PAS domain-containing protein -
K6159_RS27900 (9289) 9289..9993 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS27905 (10379) 10379..10795 + 417 WP_014839980.1 Glutathione transferase FosA ARG
K6159_RS27910 (10800) 10800..11318 - 519 WP_014839979.1 FidL-like protein -
K6159_RS27915 (11384) 11384..12088 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS27920 (12544) 12544..13134 - 591 Protein_16 IS91 family transposase ISSbo1 Transposase
K6159_RS27925 (13199) 13199..13903 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS27930 (13954) 13954..14571 - 618 Protein_18 IS91 family transposase ISSbo1 Transposase
K6159_RS27935 (14581) 14581..14769 - 189 WP_000957857.1 hypothetical protein -
K6159_RS27940 (14861) 14861..15397 + 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
K6159_RS27945 (15580) 15580..16440 + 861 WP_000027057.1 Beta-lactamase TEM ARG
K6159_RS27950 (16610) 16610..17365 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
K6159_RS27955 (17446) 17446..17760 - 315 Protein_23 hypothetical protein -
K6159_RS27960 (17815) 17815..18519 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
K6159_RS27970 (20099) 20099..20333 + 235 Protein_25 type II toxin-antitoxin system RelE/ParE family toxin -
K6159_RS27975 (20461) 20461..20742 + 282 WP_001333089.1 hypothetical protein -
K6159_RS27980 (20865) 20865..21215 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
K6159_RS27985 (21218) 21218..22180 - 963 WP_000959884.1 plasmid segregation protein ParM -
K6159_RS27990 (22327) 22327..22620 + 294 WP_032146011.1 hypothetical protein -
K6159_RS27995 (22697) 22697..23380 + 684 WP_000085883.1 DNA methylase -
K6159_RS28000 (23381) 23381..23602 + 222 WP_001104881.1 hypothetical protein -
K6159_RS28005 (23616) 23616..24050 + 435 WP_000274503.1 DUF1380 family protein -
K6159_RS28010 (24101) 24101..24877 + 777 WP_001383963.1 hypothetical protein -
K6159_RS28015 (25295) 25295..25720 + 426 WP_001198928.1 antirestriction protein -
K6159_RS28020 (25767) 25767..26189 + 423 WP_000271762.1 DUF1380 family protein -
K6159_RS28025 (26186) 26186..26377 + 192 WP_001027493.1 hypothetical protein -
K6159_RS28030 (26691) 26691..28358 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
K6159_RS30260 (29087) 29087..29241 - 155 Protein_38 hypothetical protein -
K6159_RS28035 (29758) 29758..29988 + 231 WP_000218642.1 hypothetical protein -
K6159_RS28040 (30040) 30040..31401 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
K6159_RS28045 (31448) 31448..32011 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
K6159_RS30265 (32097) 32097..32558 - 462 Protein_42 hypothetical protein -
K6159_RS28050 (32860) 32860..33387 + 528 WP_000290834.1 single-stranded DNA-binding protein -
K6159_RS28055 (33445) 33445..33678 + 234 WP_000006003.1 DUF905 family protein -
K6159_RS28060 (33739) 33739..35762 + 2024 Protein_45 ParB/RepB/Spo0J family partition protein -
K6159_RS28065 (35831) 35831..36265 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
K6159_RS28070 (36262) 36262..36981 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- (36993) 36993..37217 + 225 NuclAT_0 - -
- (36993) 36993..37217 + 225 NuclAT_0 - -
- (36993) 36993..37217 + 225 NuclAT_0 - -
- (36993) 36993..37217 + 225 NuclAT_0 - -
K6159_RS30270 (37203) 37203..37352 + 150 Protein_48 plasmid maintenance protein Mok -
K6159_RS28075 (37294) 37294..37419 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
K6159_RS28080 (37738) 37738..38034 - 297 Protein_50 hypothetical protein -
K6159_RS28085 (38334) 38334..38630 + 297 WP_001272251.1 hypothetical protein -
K6159_RS28090 (38741) 38741..39562 + 822 WP_001234445.1 DUF932 domain-containing protein -
K6159_RS28095 (39859) 39859..40506 - 648 WP_015059008.1 hypothetical protein VF
K6159_RS28100 (40783) 40783..41166 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
K6159_RS28105 (41357) 41357..42043 + 687 WP_015059009.1 PAS domain-containing protein -
K6159_RS28110 (42137) 42137..42364 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
K6159_RS28115 (42398) 42398..42763 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
K6159_RS28120 (42778) 42778..43089 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
K6159_RS28125 (43111) 43111..43677 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
K6159_RS28130 (43664) 43664..44392 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
K6159_RS28135 (44392) 44392..44595 + 204 Protein_61 IS6 family transposase IS15 Transposase
K6159_RS28140 (44661) 44661..45365 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS28145 (45419) 45419..45742 - 324 Protein_63 class II aldolase/adducin family protein -
K6159_RS28150 (45735) 45735..46987 - 1253 Protein_64 four-carbon acid sugar kinase family protein -
K6159_RS28155 (46999) 46999..47901 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
K6159_RS28160 (48163) 48163..48924 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
K6159_RS28165 (48945) 48945..49805 - 861 WP_002904004.1 Beta-lactamase SHV-2 ARG
K6159_RS28170 (49942) 49942..50010 + 69 Protein_68 IS6 family transposase -
K6159_RS28175 (50046) 50046..51944 - 1899 Protein_69 Tn3 family transposase TnpA_TnAs1 Transposase
K6159_RS28180 (52010) 52010..52714 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS28185 (52768) 52768..53091 - 324 Protein_71 class II aldolase/adducin family protein -
K6159_RS28190 (53084) 53084..54336 - 1253 Protein_72 four-carbon acid sugar kinase family protein -
K6159_RS28195 (54348) 54348..55250 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
K6159_RS28200 (55512) 55512..56273 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
K6159_RS28205 (56294) 56294..57154 - 861 WP_002904004.1 Beta-lactamase SHV-2 ARG
K6159_RS28210 (57291) 57291..57359 + 69 Protein_76 IS6 family transposase -
K6159_RS28215 (57395) 57395..59293 - 1899 Protein_77 Tn3 family transposase TnpA_TnAs1 Transposase
K6159_RS28220 (59359) 59359..60063 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS28225 (60115) 60115..60576 + 462 Protein_79 Tn3 family transposase TnpR_Tn3 Transposase
K6159_RS28230 (60699) 60699..61679 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
K6159_RS28235 (61955) 61955..62836 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
K6159_RS28240 (63086) 63086..63967 - 882 Protein_82 IS1182 family transposase ISKpn6 Transposase
K6159_RS28245 (64071) 64071..64367 - 297 WP_013213987.1 transcriptional regulator -
K6159_RS28250 (64413) 64413..64568 - 156 WP_013213988.1 hypothetical protein -
K6159_RS28255 (64696) 64696..65121 - 426 WP_013213989.1 antirestriction protein -
K6159_RS28260 (65232) 65232..65510 - 279 WP_013213990.1 hypothetical protein -
K6159_RS28265 (66044) 66044..66661 - 618 Protein_87 replication protein -
K6159_RS28270 (67053) 67053..67613 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
K6159_RS28275 (67617) 67617..68690 + 1074 Protein_89 Tn3 family transposase TnpA_TnAs1 Transposase
K6159_RS28280 (68743) 68743..69447 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS30275 (69511) 69511..69720 - 210 Protein_91 replication initiation protein -
K6159_RS28285 (70256) 70256..70369 + 114 WP_014343462.1 hypothetical protein -
K6159_RS28290 (70498) 70498..70755 + 258 WP_013214010.1 hypothetical protein -
K6159_RS28295 (70801) 70801..71580 - 780 WP_013214009.1 site-specific integrase -
K6159_RS28300 (71764) 71764..72768 - 1005 WP_011977814.1 hypothetical protein -
K6159_RS28305 (72798) 72798..73001 - 204 WP_011977813.1 hypothetical protein -
K6159_RS28310 (73047) 73047..73568 - 522 WP_013214008.1 hypothetical protein -
K6159_RS28315 (73626) 73626..74018 - 393 WP_011977811.1 hypothetical protein -
K6159_RS28320 (74055) 74055..74999 - 945 WP_011977810.1 hypothetical protein -
K6159_RS28325 (75160) 75160..75621 - 462 WP_014343465.1 hypothetical protein -
K6159_RS28330 (75578) 75578..75808 + 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
K6159_RS28335 (75805) 75805..76221 + 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
K6159_RS28340 (76295) 76295..77857 + 1563 WP_004206609.1 AAA family ATPase -
K6159_RS28345 (77842) 77842..78864 + 1023 WP_000361404.1 helicase UvrD -
K6159_RS28350 (79120) 79120..79817 + 698 WP_223174630.1 IS1 family transposase ISKpn14 Transposase
K6159_RS28355 (79846) 79846..80118 + 273 Protein_106 transposase -
K6159_RS28360 (80398) 80398..81402 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
K6159_RS28365 (81481) 81481..81915 - 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
K6159_RS28370 (81987) 81987..82337 + 351 WP_001294663.1 mercuric transport protein MerT -
K6159_RS28375 (82351) 82351..82626 + 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
K6159_RS28380 (82662) 82662..83084 + 423 WP_001340589.1 organomercurial transporter MerC -
K6159_RS28385 (83136) 83136..84830 + 1695 WP_000105636.1 mercury(II) reductase -
K6159_RS28390 (84848) 84848..85210 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
K6159_RS28395 (85207) 85207..85443 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
K6159_RS28400 (85479) 85479..86147 + 669 WP_001300294.1 putative signaling protein VF
K6159_RS28405 (86222) 86222..87394 + 1173 Protein_116 transposase -
K6159_RS28410 (87459) 87459..88163 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS28415 (88173) 88173..88880 + 708 WP_222666140.1 replication initiation protein -
K6159_RS28420 (89990) 89990..91195 + 1206 WP_011977818.1 AAA family ATPase -
K6159_RS28425 (91195) 91195..92169 + 975 WP_011977819.1 ParB family protein -
K6159_RS28430 (92251) 92251..93522 - 1272 WP_013214011.1 Y-family DNA polymerase -
K6159_RS28435 (93522) 93522..93953 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
K6159_RS28440 (94360) 94360..95847 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
K6159_RS28445 (96096) 96096..97067 + 972 WP_004152353.1 plasmid segregation protein ParM -
K6159_RS28450 (97070) 97070..97741 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
K6159_RS28455 (97804) 97804..98034 + 231 WP_001568040.1 hypothetical protein -
K6159_RS30280 (98230) 98230..98399 + 170 Protein_127 hypothetical protein -
K6159_RS28460 (98471) 98471..99172 + 702 WP_151488309.1 DNA methylase -
K6159_RS28465 (99172) 99172..99393 + 222 WP_001568042.1 hypothetical protein -
K6159_RS28470 (99403) 99403..99822 + 420 WP_001568043.1 DUF1380 domain-containing protein -
K6159_RS28475 (99876) 99876..100643 + 768 WP_013214013.1 hypothetical protein -
K6159_RS28480 (101324) 101324..101752 + 429 WP_001568045.1 antirestriction protein -
K6159_RS28485 (101795) 101795..102301 + 507 WP_013214014.1 antirestriction protein ArdA -
K6159_RS28490 (102344) 102344..102535 + 192 WP_001568047.1 hypothetical protein -
K6159_RS28495 (102723) 102723..102977 + 255 WP_011977779.1 DNA polymerase III subunit theta -
K6159_RS28500 (103012) 103012..103332 + 321 WP_001568049.1 hypothetical protein -
K6159_RS28505 (104012) 104012..104239 + 228 WP_001568050.1 hypothetical protein -
K6159_RS28510 (104331) 104331..104561 + 231 WP_001568051.1 hypothetical protein -
K6159_RS28515 (104613) 104613..105968 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
K6159_RS28520 (106016) 106016..106579 + 564 WP_014343514.1 methyltransferase -
K6159_RS28525 (107411) 107411..107953 + 543 WP_014343512.1 single-stranded DNA-binding protein -
K6159_RS28530 (108002) 108002..108250 + 249 WP_001568055.1 DUF905 domain-containing protein -
K6159_RS28535 (108320) 108320..110377 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
K6159_RS28540 (110422) 110422..110853 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
K6159_RS28545 (110850) 110850..111578 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
K6159_RS28550 (111575) 111575..111901 + 327 WP_013023807.1 hypothetical protein -
K6159_RS28555 (111957) 111957..112331 + 375 WP_014343510.1 hypothetical protein -
K6159_RS30285 (112501) 112501..112650 + 150 Protein_148 DUF5431 family protein -
K6159_RS28560 (112601) 112601..112717 + 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
K6159_RS28565 (113410) 113410..113682 + 273 WP_040245921.1 hypothetical protein -
K6159_RS28570 (113679) 113679..114029 + 351 WP_040245917.1 hypothetical protein -
K6159_RS28575 (114044) 114044..114361 + 318 WP_014343505.1 hypothetical protein -
K6159_RS28580 (115202) 115202..115558 + 357 WP_014343501.1 hypothetical protein -
K6159_RS28585 (115619) 115619..115831 + 213 WP_014343500.1 hypothetical protein -
K6159_RS28590 (115842) 115842..116066 + 225 WP_014343499.1 hypothetical protein -
K6159_RS28595 (116147) 116147..116467 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
K6159_RS28600 (116457) 116457..116735 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
K6159_RS30290 (116739) 116739..116843 + 105 Protein_158 transcriptional regulator -
K6159_RS28605 (117421) 117421..118124 - 704 Protein_159 IS6 family transposase IS15DII Transposase
K6159_RS28610 (118453) 118453..119403 + 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
K6159_RS28615 (119400) 119400..120011 - 612 WP_015493086.1 DUF2913 family protein -
K6159_RS28620 (120008) 120008..120403 - 396 WP_015493087.1 hypothetical protein -
K6159_RS28625 (120456) 120456..120848 - 393 Protein_163 3'-5' exonuclease -
K6159_RS28630 (120917) 120917..121897 + 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
K6159_RS28635 (121879) 121879..122421 + 543 WP_077273850.1 restriction endonuclease -
K6159_RS28640 (122549) 122549..123106 + 558 WP_042934582.1 hypothetical protein -
K6159_RS28645 (123575) 123575..124279 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS28650 (124285) 124285..124425 + 141 WP_001044210.1 hypothetical protein -
K6159_RS28655 (124911) 124911..125648 + 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
K6159_RS28660 (125645) 125645..125869 + 225 WP_000743213.1 hypothetical protein -
K6159_RS30295 (125991) 125991..126077 + 87 Protein_171 Arm DNA-binding domain-containing protein -
K6159_RS28670 (126349) 126349..127353 - 1005 WP_000427614.1 IS110 family transposase IS5075 Transposase
K6159_RS28675 (127432) 127432..130398 - 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
K6159_RS28680 (130401) 130401..130466 - 66 Protein_174 helix-turn-helix domain-containing protein -
K6159_RS28685 (130519) 130519..131223 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6159_RS28690 (131248) 131248..131448 + 201 WP_072354025.1 hypothetical protein -
K6159_RS28695 (131468) 131468..132214 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
K6159_RS28700 (132269) 132269..132829 + 561 WP_000139328.1 fertility inhibition protein FinO -
K6159_RS28705 (132961) 132961..133161 + 201 WP_015059022.1 hypothetical protein -
K6159_RS28710 (133547) 133547..134146 + 600 WP_032083981.1 PIN domain-containing protein -
K6159_RS28715 (134208) 134208..134540 + 333 WP_152916585.1 hypothetical protein -
- (134741) 134741..134800 - 60 NuclAT_1 - Antitoxin Detail
- (134741) 134741..134800 - 60 NuclAT_1 - Antitoxin Detail
- (134741) 134741..134800 - 60 NuclAT_1 - Antitoxin Detail
- (134741) 134741..134800 - 60 NuclAT_1 - Antitoxin Detail
K6159_RS28720 (134845) 134845..134994 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
K6159_RS28725 (135278) 135278..135526 + 249 WP_000083837.1 replication regulatory protein RepA -
K6159_RS30300 (135641) 135641..135825 + 185 Protein_184 protein CopA/IncA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance