NZ_CP0820151..128480

MGE detailed information

MGE type: Mobilizable plasmid        MGE length: 128480 bp
Accession: NZ_CP082015        Location: 1..128480         Organism: Klebsiella pneumoniae strain KP18-238       Replicon: plasmid pKP18-238-KPC2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6162_RS27700 (194) 194..514 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
K6162_RS27705 (504) 504..782 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
K6162_RS29400 (786) 786..890 + 105 Protein_3 transcriptional regulator -
K6162_RS27710 (1064) 1064..1768 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS27715 (2097) 2097..3047 + 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
K6162_RS27720 (3044) 3044..3655 - 612 WP_015493086.1 DUF2913 family protein -
K6162_RS27725 (3652) 3652..4047 - 396 WP_015493087.1 hypothetical protein -
K6162_RS27730 (4100) 4100..4492 - 393 Protein_8 3'-5' exonuclease -
K6162_RS27735 (4561) 4561..5541 + 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
K6162_RS27740 (5523) 5523..6065 + 543 WP_077273850.1 restriction endonuclease -
K6162_RS27745 (6193) 6193..6750 + 558 WP_042934582.1 hypothetical protein -
K6162_RS27750 (7219) 7219..7923 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS27755 (8056) 8056..8697 - 642 WP_001011939.1 Chloramphenicol acetyltransferase 2 ARG
K6162_RS27760 (8847) 8847..9347 - 501 WP_001239317.1 hypothetical protein -
K6162_RS27765 (9427) 9427..10131 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS27770 (10137) 10137..10277 + 141 WP_001044210.1 hypothetical protein -
K6162_RS27775 (10763) 10763..11500 + 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
K6162_RS27780 (11497) 11497..11721 + 225 WP_000743213.1 hypothetical protein -
K6162_RS29405 (11843) 11843..11929 + 87 Protein_19 Arm DNA-binding domain-containing protein -
K6162_RS27790 (12201) 12201..13205 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
K6162_RS27795 (13284) 13284..16250 - 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
K6162_RS27800 (16253) 16253..16318 - 66 Protein_22 helix-turn-helix domain-containing protein -
K6162_RS27805 (16371) 16371..17075 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS27810 (17100) 17100..17300 + 201 WP_072354025.1 hypothetical protein -
K6162_RS27815 (17320) 17320..18066 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
K6162_RS27820 (18121) 18121..18681 + 561 WP_000139328.1 fertility inhibition protein FinO -
K6162_RS27825 (18813) 18813..19013 + 201 WP_015059022.1 hypothetical protein -
K6162_RS27830 (19399) 19399..19998 + 600 WP_032083981.1 PIN domain-containing protein -
K6162_RS27835 (20060) 20060..20392 + 333 WP_152916585.1 hypothetical protein -
- (20593) 20593..20652 - 60 NuclAT_1 - Antitoxin Detail
- (20593) 20593..20652 - 60 NuclAT_1 - Antitoxin Detail
- (20593) 20593..20652 - 60 NuclAT_1 - Antitoxin Detail
- (20593) 20593..20652 - 60 NuclAT_1 - Antitoxin Detail
K6162_RS27840 (20697) 20697..20846 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
K6162_RS27845 (21130) 21130..21378 + 249 WP_000083837.1 replication regulatory protein RepA -
K6162_RS29410 (21493) 21493..21671 + 179 Protein_32 protein CopA/IncA -
K6162_RS27855 (21690) 21690..22547 + 858 WP_142295464.1 incFII family plasmid replication initiator RepA -
K6162_RS27860 (23486) 23486..24139 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
K6162_RS27865 (24232) 24232..24489 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
K6162_RS27870 (24422) 24422..24823 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
K6162_RS27875 (25072) 25072..25487 + 416 Protein_37 IS1 family transposase IS1R Transposase
K6162_RS27880 (25523) 25523..26068 - 546 Protein_38 Tn3 family transposase TnpA_Tn3 Transposase
K6162_RS27885 (26134) 26134..26838 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS27890 (26908) 26908..27099 + 192 Protein_40 IS1380 family transposase -
K6162_RS27895 (27349) 27349..28224 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
K6162_RS27900 (28259) 28259..29227 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
K6162_RS27905 (29284) 29284..30381 + 1098 Protein_43 TonB-dependent receptor -
K6162_RS27910 (30449) 30449..30925 - 477 Protein_44 PAS domain-containing protein -
K6162_RS27915 (30978) 30978..31682 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS27920 (32068) 32068..32484 + 417 WP_014839980.1 Glutathione transferase FosA ARG
K6162_RS27925 (32489) 32489..33007 - 519 WP_014839979.1 FidL-like protein -
K6162_RS27930 (33073) 33073..33777 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS27935 (34233) 34233..34823 - 591 Protein_49 IS91 family transposase ISSbo1 Transposase
K6162_RS27940 (34888) 34888..35592 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS27945 (35648) 35648..36106 + 459 Protein_51 Tn3 family transposase TnpR_Tn3 Transposase
K6162_RS27950 (36289) 36289..37149 + 861 WP_000027057.1 Beta-lactamase TEM ARG
K6162_RS27955 (37319) 37319..38074 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
K6162_RS27960 (38155) 38155..38469 - 315 Protein_54 hypothetical protein -
K6162_RS27965 (38524) 38524..39228 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
K6162_RS27975 (40808) 40808..41042 + 235 Protein_56 type II toxin-antitoxin system RelE/ParE family toxin -
K6162_RS27980 (41170) 41170..41451 + 282 WP_001333089.1 hypothetical protein -
K6162_RS27985 (41574) 41574..41924 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
K6162_RS27990 (41927) 41927..42889 - 963 WP_000959884.1 plasmid segregation protein ParM -
K6162_RS27995 (43036) 43036..43329 + 294 WP_032146011.1 hypothetical protein -
K6162_RS28000 (43406) 43406..44089 + 684 WP_000085883.1 DNA methylase -
K6162_RS28005 (44090) 44090..44311 + 222 WP_001104881.1 hypothetical protein -
K6162_RS28010 (44325) 44325..44759 + 435 WP_000274503.1 DUF1380 family protein -
K6162_RS28015 (44810) 44810..45586 + 777 WP_001383963.1 hypothetical protein -
K6162_RS28020 (46004) 46004..46429 + 426 WP_001198928.1 antirestriction protein -
K6162_RS28025 (46476) 46476..46898 + 423 WP_000271762.1 DUF1380 family protein -
K6162_RS28030 (46895) 46895..47086 + 192 WP_001027493.1 hypothetical protein -
K6162_RS28035 (47400) 47400..49067 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
K6162_RS29420 (49796) 49796..49950 - 155 Protein_69 hypothetical protein -
K6162_RS28040 (50467) 50467..50697 + 231 WP_000218642.1 hypothetical protein -
K6162_RS28045 (50749) 50749..52110 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
K6162_RS28050 (52157) 52157..52720 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
K6162_RS29425 (52806) 52806..53267 - 462 Protein_73 hypothetical protein -
K6162_RS28055 (53569) 53569..54096 + 528 WP_000290834.1 single-stranded DNA-binding protein -
K6162_RS28060 (54154) 54154..54387 + 234 WP_000006003.1 DUF905 family protein -
K6162_RS28065 (54448) 54448..56471 + 2024 Protein_76 ParB/RepB/Spo0J family partition protein -
K6162_RS28070 (56540) 56540..56974 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
K6162_RS28075 (56971) 56971..57690 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- (57702) 57702..57926 + 225 NuclAT_0 - -
- (57702) 57702..57926 + 225 NuclAT_0 - -
- (57702) 57702..57926 + 225 NuclAT_0 - -
- (57702) 57702..57926 + 225 NuclAT_0 - -
K6162_RS29430 (57912) 57912..58061 + 150 Protein_79 plasmid maintenance protein Mok -
K6162_RS28080 (58003) 58003..58128 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
K6162_RS28085 (58447) 58447..58743 - 297 Protein_81 hypothetical protein -
K6162_RS28090 (59043) 59043..59339 + 297 WP_001272251.1 hypothetical protein -
K6162_RS28095 (59450) 59450..60271 + 822 WP_001234445.1 DUF932 domain-containing protein -
K6162_RS28100 (60568) 60568..61215 - 648 WP_015059008.1 hypothetical protein VF
K6162_RS28105 (61492) 61492..61875 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
K6162_RS28110 (62066) 62066..62752 + 687 WP_015059009.1 PAS domain-containing protein -
K6162_RS28115 (62846) 62846..63073 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
K6162_RS28120 (63107) 63107..63472 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
K6162_RS28125 (63487) 63487..63798 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
K6162_RS28130 (63820) 63820..64386 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
K6162_RS28135 (64373) 64373..65101 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
K6162_RS28140 (65101) 65101..65304 + 204 Protein_92 IS6 family transposase IS15 Transposase
K6162_RS28145 (65370) 65370..66074 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS28150 (66128) 66128..66451 - 324 Protein_94 class II aldolase/adducin family protein -
K6162_RS28155 (66444) 66444..67696 - 1253 Protein_95 four-carbon acid sugar kinase family protein -
K6162_RS28160 (67708) 67708..68610 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
K6162_RS28165 (68872) 68872..69633 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
K6162_RS28170 (69654) 69654..70510 - 857 Protein_98 Beta-lactamase SHV-2 ARG
K6162_RS28175 (70647) 70647..70715 + 69 Protein_99 IS6 family transposase -
K6162_RS28180 (70751) 70751..72649 - 1899 Protein_100 Tn3 family transposase TnpA_TnAs1 Transposase
K6162_RS28185 (72715) 72715..73418 + 704 Protein_101 IS6 family transposase IS15DII Transposase
K6162_RS28190 (73470) 73470..73949 + 480 Protein_102 Tn3 family transposase TnpR_Tn3 Transposase
K6162_RS28195 (74055) 74055..75035 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
K6162_RS28200 (75311) 75311..76192 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
K6162_RS28205 (76442) 76442..77323 - 882 Protein_105 IS1182 family transposase ISKpn6 Transposase
K6162_RS28210 (77427) 77427..77723 - 297 WP_013213987.1 transcriptional regulator -
K6162_RS28215 (77769) 77769..77924 - 156 WP_013213988.1 hypothetical protein -
K6162_RS28220 (78052) 78052..78477 - 426 WP_013213989.1 antirestriction protein -
K6162_RS28225 (78588) 78588..78866 - 279 WP_013213990.1 hypothetical protein -
K6162_RS28230 (79400) 79400..80017 - 618 Protein_110 replication protein -
K6162_RS28235 (80409) 80409..80969 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
K6162_RS28240 (80973) 80973..82046 + 1074 Protein_112 Tn3 family transposase TnpA_TnAs1 Transposase
K6162_RS28245 (82099) 82099..82803 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6162_RS28250 (82868) 82868..84040 - 1173 Protein_114 transposase -
K6162_RS28255 (84115) 84115..84783 - 669 WP_001300294.1 putative signaling protein VF
K6162_RS28260 (84819) 84819..85055 - 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
K6162_RS28265 (85052) 85052..85414 - 363 WP_001277456.1 mercury resistance co-regulator MerD -
K6162_RS28270 (85432) 85432..87126 - 1695 WP_000105636.1 mercury(II) reductase -
K6162_RS28275 (87178) 87178..87600 - 423 WP_001340589.1 organomercurial transporter MerC -
K6162_RS28280 (87636) 87636..87911 - 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
K6162_RS28285 (87925) 87925..88275 - 351 WP_001294663.1 mercuric transport protein MerT -
K6162_RS28290 (88347) 88347..88781 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
K6162_RS28295 (88860) 88860..89863 + 1004 Protein_123 IS110 family transposase IS4321 Transposase
K6162_RS28300 (90143) 90143..90415 - 273 Protein_124 transposase -
K6162_RS28305 (90887) 90887..90888 - 2 WP_024269734.1 IS1 family transposase ISKpn14 Transposase
K6162_RS28310 (91396) 91396..92418 - 1023 WP_000361404.1 helicase UvrD -
K6162_RS28315 (92403) 92403..93965 - 1563 WP_004206609.1 AAA family ATPase -
K6162_RS28320 (94039) 94039..94455 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
K6162_RS28325 (94452) 94452..94682 - 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
K6162_RS28330 (94639) 94639..95100 + 462 WP_014343465.1 hypothetical protein -
K6162_RS28335 (95261) 95261..96205 + 945 WP_011977810.1 hypothetical protein -
K6162_RS28340 (96242) 96242..96634 + 393 WP_011977811.1 hypothetical protein -
K6162_RS28345 (96692) 96692..97213 + 522 WP_013214008.1 hypothetical protein -
K6162_RS28350 (97259) 97259..97462 + 204 WP_011977813.1 hypothetical protein -
K6162_RS28355 (97492) 97492..98496 + 1005 WP_011977814.1 hypothetical protein -
K6162_RS28360 (98680) 98680..99459 + 780 WP_013214009.1 site-specific integrase -
K6162_RS28365 (99505) 99505..99762 - 258 WP_013214010.1 hypothetical protein -
K6162_RS28370 (99891) 99891..100004 - 114 WP_014343462.1 hypothetical protein -
K6162_RS28375 (100540) 100540..101406 + 867 WP_004118283.1 replication initiation protein -
K6162_RS28380 (102516) 102516..103721 + 1206 WP_011977818.1 AAA family ATPase -
K6162_RS28385 (103721) 103721..104695 + 975 WP_011977819.1 ParB family protein -
K6162_RS28390 (104777) 104777..106048 - 1272 WP_013214011.1 Y-family DNA polymerase -
K6162_RS28395 (106048) 106048..106479 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
K6162_RS28400 (106886) 106886..108373 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
K6162_RS28405 (108622) 108622..109593 + 972 WP_004152353.1 plasmid segregation protein ParM -
K6162_RS28410 (109596) 109596..110267 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
K6162_RS28415 (110330) 110330..110560 + 231 WP_001568040.1 hypothetical protein -
K6162_RS29435 (110756) 110756..110925 + 170 Protein_148 hypothetical protein -
K6162_RS28420 (110997) 110997..111698 + 702 WP_151488309.1 DNA methylase -
K6162_RS28425 (111698) 111698..111919 + 222 WP_001568042.1 hypothetical protein -
K6162_RS28430 (111929) 111929..112348 + 420 WP_001568043.1 DUF1380 domain-containing protein -
K6162_RS28435 (112402) 112402..113169 + 768 WP_013214013.1 hypothetical protein -
K6162_RS28440 (113850) 113850..114278 + 429 WP_001568045.1 antirestriction protein -
K6162_RS28445 (114321) 114321..114827 + 507 WP_013214014.1 antirestriction protein ArdA -
K6162_RS28450 (114870) 114870..115061 + 192 WP_001568047.1 hypothetical protein -
K6162_RS28455 (115249) 115249..115503 + 255 WP_011977779.1 DNA polymerase III subunit theta -
K6162_RS28460 (115538) 115538..115858 + 321 WP_001568049.1 hypothetical protein -
K6162_RS28465 (116538) 116538..116765 + 228 WP_001568050.1 hypothetical protein -
K6162_RS28470 (116857) 116857..117087 + 231 WP_001568051.1 hypothetical protein -
K6162_RS28475 (117139) 117139..118494 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
K6162_RS28480 (118542) 118542..119105 + 564 WP_014343514.1 methyltransferase -
K6162_RS28485 (119938) 119938..120480 + 543 WP_014343512.1 single-stranded DNA-binding protein -
K6162_RS28490 (120529) 120529..120777 + 249 WP_001568055.1 DUF905 domain-containing protein -
K6162_RS28495 (120847) 120847..122904 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
K6162_RS28500 (122949) 122949..123380 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
K6162_RS28505 (123377) 123377..124105 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
K6162_RS28510 (124102) 124102..124428 + 327 WP_013023807.1 hypothetical protein -
K6162_RS28515 (124484) 124484..124858 + 375 WP_014343510.1 hypothetical protein -
K6162_RS29440 (125028) 125028..125177 + 150 Protein_169 DUF5431 family protein -
K6162_RS28520 (125128) 125128..125244 + 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
K6162_RS28525 (125937) 125937..126209 + 273 WP_040245921.1 hypothetical protein -
K6162_RS28530 (126206) 126206..126556 + 351 WP_040245917.1 hypothetical protein -
K6162_RS28535 (126571) 126571..126888 + 318 WP_014343505.1 hypothetical protein -
K6162_RS28540 (127729) 127729..128085 + 357 WP_014343501.1 hypothetical protein -
K6162_RS28545 (128146) 128146..128358 + 213 WP_014343500.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance