MGE detailed information
MGE type: Mobilizable plasmid MGE length: 128480 bp
Accession: NZ_CP082015 Location: 1..128480 Organism: Klebsiella pneumoniae strain KP18-238 Replicon: plasmid pKP18-238-KPC2
Accession: NZ_CP082015 Location: 1..128480 Organism: Klebsiella pneumoniae strain KP18-238 Replicon: plasmid pKP18-238-KPC2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
K6162_RS27700 (194) | 194..514 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
K6162_RS27705 (504) | 504..782 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
K6162_RS29400 (786) | 786..890 | + | 105 | Protein_3 | transcriptional regulator | - |
K6162_RS27710 (1064) | 1064..1768 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS27715 (2097) | 2097..3047 | + | 951 | WP_015493085.1 | Recombination-promoting nuclease RpnA | VF |
K6162_RS27720 (3044) | 3044..3655 | - | 612 | WP_015493086.1 | DUF2913 family protein | - |
K6162_RS27725 (3652) | 3652..4047 | - | 396 | WP_015493087.1 | hypothetical protein | - |
K6162_RS27730 (4100) | 4100..4492 | - | 393 | Protein_8 | 3'-5' exonuclease | - |
K6162_RS27735 (4561) | 4561..5541 | + | 981 | WP_000019445.1 | IS5 family transposase ISKpn26 | Transposase |
K6162_RS27740 (5523) | 5523..6065 | + | 543 | WP_077273850.1 | restriction endonuclease | - |
K6162_RS27745 (6193) | 6193..6750 | + | 558 | WP_042934582.1 | hypothetical protein | - |
K6162_RS27750 (7219) | 7219..7923 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS27755 (8056) | 8056..8697 | - | 642 | WP_001011939.1 | Chloramphenicol acetyltransferase 2 | ARG |
K6162_RS27760 (8847) | 8847..9347 | - | 501 | WP_001239317.1 | hypothetical protein | - |
K6162_RS27765 (9427) | 9427..10131 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS27770 (10137) | 10137..10277 | + | 141 | WP_001044210.1 | hypothetical protein | - |
K6162_RS27775 (10763) | 10763..11500 | + | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
K6162_RS27780 (11497) | 11497..11721 | + | 225 | WP_000743213.1 | hypothetical protein | - |
K6162_RS29405 (11843) | 11843..11929 | + | 87 | Protein_19 | Arm DNA-binding domain-containing protein | - |
K6162_RS27790 (12201) | 12201..13205 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
K6162_RS27795 (13284) | 13284..16250 | - | 2967 | WP_042863651.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
K6162_RS27800 (16253) | 16253..16318 | - | 66 | Protein_22 | helix-turn-helix domain-containing protein | - |
K6162_RS27805 (16371) | 16371..17075 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS27810 (17100) | 17100..17300 | + | 201 | WP_072354025.1 | hypothetical protein | - |
K6162_RS27815 (17320) | 17320..18066 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
K6162_RS27820 (18121) | 18121..18681 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
K6162_RS27825 (18813) | 18813..19013 | + | 201 | WP_015059022.1 | hypothetical protein | - |
K6162_RS27830 (19399) | 19399..19998 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
K6162_RS27835 (20060) | 20060..20392 | + | 333 | WP_152916585.1 | hypothetical protein | - |
- (20593) | 20593..20652 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
- (20593) | 20593..20652 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
- (20593) | 20593..20652 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
- (20593) | 20593..20652 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
K6162_RS27840 (20697) | 20697..20846 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
K6162_RS27845 (21130) | 21130..21378 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
K6162_RS29410 (21493) | 21493..21671 | + | 179 | Protein_32 | protein CopA/IncA | - |
K6162_RS27855 (21690) | 21690..22547 | + | 858 | WP_142295464.1 | incFII family plasmid replication initiator RepA | - |
K6162_RS27860 (23486) | 23486..24139 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
K6162_RS27865 (24232) | 24232..24489 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
K6162_RS27870 (24422) | 24422..24823 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
K6162_RS27875 (25072) | 25072..25487 | + | 416 | Protein_37 | IS1 family transposase IS1R | Transposase |
K6162_RS27880 (25523) | 25523..26068 | - | 546 | Protein_38 | Tn3 family transposase TnpA_Tn3 | Transposase |
K6162_RS27885 (26134) | 26134..26838 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS27890 (26908) | 26908..27099 | + | 192 | Protein_40 | IS1380 family transposase | - |
K6162_RS27895 (27349) | 27349..28224 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
K6162_RS27900 (28259) | 28259..29227 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
K6162_RS27905 (29284) | 29284..30381 | + | 1098 | Protein_43 | TonB-dependent receptor | - |
K6162_RS27910 (30449) | 30449..30925 | - | 477 | Protein_44 | PAS domain-containing protein | - |
K6162_RS27915 (30978) | 30978..31682 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS27920 (32068) | 32068..32484 | + | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
K6162_RS27925 (32489) | 32489..33007 | - | 519 | WP_014839979.1 | FidL-like protein | - |
K6162_RS27930 (33073) | 33073..33777 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS27935 (34233) | 34233..34823 | - | 591 | Protein_49 | IS91 family transposase ISSbo1 | Transposase |
K6162_RS27940 (34888) | 34888..35592 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS27945 (35648) | 35648..36106 | + | 459 | Protein_51 | Tn3 family transposase TnpR_Tn3 | Transposase |
K6162_RS27950 (36289) | 36289..37149 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
K6162_RS27955 (37319) | 37319..38074 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
K6162_RS27960 (38155) | 38155..38469 | - | 315 | Protein_54 | hypothetical protein | - |
K6162_RS27965 (38524) | 38524..39228 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
K6162_RS27975 (40808) | 40808..41042 | + | 235 | Protein_56 | type II toxin-antitoxin system RelE/ParE family toxin | - |
K6162_RS27980 (41170) | 41170..41451 | + | 282 | WP_001333089.1 | hypothetical protein | - |
K6162_RS27985 (41574) | 41574..41924 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
K6162_RS27990 (41927) | 41927..42889 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
K6162_RS27995 (43036) | 43036..43329 | + | 294 | WP_032146011.1 | hypothetical protein | - |
K6162_RS28000 (43406) | 43406..44089 | + | 684 | WP_000085883.1 | DNA methylase | - |
K6162_RS28005 (44090) | 44090..44311 | + | 222 | WP_001104881.1 | hypothetical protein | - |
K6162_RS28010 (44325) | 44325..44759 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
K6162_RS28015 (44810) | 44810..45586 | + | 777 | WP_001383963.1 | hypothetical protein | - |
K6162_RS28020 (46004) | 46004..46429 | + | 426 | WP_001198928.1 | antirestriction protein | - |
K6162_RS28025 (46476) | 46476..46898 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
K6162_RS28030 (46895) | 46895..47086 | + | 192 | WP_001027493.1 | hypothetical protein | - |
K6162_RS28035 (47400) | 47400..49067 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
K6162_RS29420 (49796) | 49796..49950 | - | 155 | Protein_69 | hypothetical protein | - |
K6162_RS28040 (50467) | 50467..50697 | + | 231 | WP_000218642.1 | hypothetical protein | - |
K6162_RS28045 (50749) | 50749..52110 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
K6162_RS28050 (52157) | 52157..52720 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
K6162_RS29425 (52806) | 52806..53267 | - | 462 | Protein_73 | hypothetical protein | - |
K6162_RS28055 (53569) | 53569..54096 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
K6162_RS28060 (54154) | 54154..54387 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
K6162_RS28065 (54448) | 54448..56471 | + | 2024 | Protein_76 | ParB/RepB/Spo0J family partition protein | - |
K6162_RS28070 (56540) | 56540..56974 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
K6162_RS28075 (56971) | 56971..57690 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
- (57702) | 57702..57926 | + | 225 | NuclAT_0 | - | - |
- (57702) | 57702..57926 | + | 225 | NuclAT_0 | - | - |
- (57702) | 57702..57926 | + | 225 | NuclAT_0 | - | - |
- (57702) | 57702..57926 | + | 225 | NuclAT_0 | - | - |
K6162_RS29430 (57912) | 57912..58061 | + | 150 | Protein_79 | plasmid maintenance protein Mok | - |
K6162_RS28080 (58003) | 58003..58128 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
K6162_RS28085 (58447) | 58447..58743 | - | 297 | Protein_81 | hypothetical protein | - |
K6162_RS28090 (59043) | 59043..59339 | + | 297 | WP_001272251.1 | hypothetical protein | - |
K6162_RS28095 (59450) | 59450..60271 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
K6162_RS28100 (60568) | 60568..61215 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
K6162_RS28105 (61492) | 61492..61875 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
K6162_RS28110 (62066) | 62066..62752 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
K6162_RS28115 (62846) | 62846..63073 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
K6162_RS28120 (63107) | 63107..63472 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
K6162_RS28125 (63487) | 63487..63798 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
K6162_RS28130 (63820) | 63820..64386 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
K6162_RS28135 (64373) | 64373..65101 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
K6162_RS28140 (65101) | 65101..65304 | + | 204 | Protein_92 | IS6 family transposase IS15 | Transposase |
K6162_RS28145 (65370) | 65370..66074 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS28150 (66128) | 66128..66451 | - | 324 | Protein_94 | class II aldolase/adducin family protein | - |
K6162_RS28155 (66444) | 66444..67696 | - | 1253 | Protein_95 | four-carbon acid sugar kinase family protein | - |
K6162_RS28160 (67708) | 67708..68610 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
K6162_RS28165 (68872) | 68872..69633 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
K6162_RS28170 (69654) | 69654..70510 | - | 857 | Protein_98 | Beta-lactamase SHV-2 | ARG |
K6162_RS28175 (70647) | 70647..70715 | + | 69 | Protein_99 | IS6 family transposase | - |
K6162_RS28180 (70751) | 70751..72649 | - | 1899 | Protein_100 | Tn3 family transposase TnpA_TnAs1 | Transposase |
K6162_RS28185 (72715) | 72715..73418 | + | 704 | Protein_101 | IS6 family transposase IS15DII | Transposase |
K6162_RS28190 (73470) | 73470..73949 | + | 480 | Protein_102 | Tn3 family transposase TnpR_Tn3 | Transposase |
K6162_RS28195 (74055) | 74055..75035 | + | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
K6162_RS28200 (75311) | 75311..76192 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
K6162_RS28205 (76442) | 76442..77323 | - | 882 | Protein_105 | IS1182 family transposase ISKpn6 | Transposase |
K6162_RS28210 (77427) | 77427..77723 | - | 297 | WP_013213987.1 | transcriptional regulator | - |
K6162_RS28215 (77769) | 77769..77924 | - | 156 | WP_013213988.1 | hypothetical protein | - |
K6162_RS28220 (78052) | 78052..78477 | - | 426 | WP_013213989.1 | antirestriction protein | - |
K6162_RS28225 (78588) | 78588..78866 | - | 279 | WP_013213990.1 | hypothetical protein | - |
K6162_RS28230 (79400) | 79400..80017 | - | 618 | Protein_110 | replication protein | - |
K6162_RS28235 (80409) | 80409..80969 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
K6162_RS28240 (80973) | 80973..82046 | + | 1074 | Protein_112 | Tn3 family transposase TnpA_TnAs1 | Transposase |
K6162_RS28245 (82099) | 82099..82803 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
K6162_RS28250 (82868) | 82868..84040 | - | 1173 | Protein_114 | transposase | - |
K6162_RS28255 (84115) | 84115..84783 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
K6162_RS28260 (84819) | 84819..85055 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
K6162_RS28265 (85052) | 85052..85414 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
K6162_RS28270 (85432) | 85432..87126 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
K6162_RS28275 (87178) | 87178..87600 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
K6162_RS28280 (87636) | 87636..87911 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
K6162_RS28285 (87925) | 87925..88275 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
K6162_RS28290 (88347) | 88347..88781 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
K6162_RS28295 (88860) | 88860..89863 | + | 1004 | Protein_123 | IS110 family transposase IS4321 | Transposase |
K6162_RS28300 (90143) | 90143..90415 | - | 273 | Protein_124 | transposase | - |
K6162_RS28305 (90887) | 90887..90888 | - | 2 | WP_024269734.1 | IS1 family transposase ISKpn14 | Transposase |
K6162_RS28310 (91396) | 91396..92418 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
K6162_RS28315 (92403) | 92403..93965 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
K6162_RS28320 (94039) | 94039..94455 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
K6162_RS28325 (94452) | 94452..94682 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
K6162_RS28330 (94639) | 94639..95100 | + | 462 | WP_014343465.1 | hypothetical protein | - |
K6162_RS28335 (95261) | 95261..96205 | + | 945 | WP_011977810.1 | hypothetical protein | - |
K6162_RS28340 (96242) | 96242..96634 | + | 393 | WP_011977811.1 | hypothetical protein | - |
K6162_RS28345 (96692) | 96692..97213 | + | 522 | WP_013214008.1 | hypothetical protein | - |
K6162_RS28350 (97259) | 97259..97462 | + | 204 | WP_011977813.1 | hypothetical protein | - |
K6162_RS28355 (97492) | 97492..98496 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
K6162_RS28360 (98680) | 98680..99459 | + | 780 | WP_013214009.1 | site-specific integrase | - |
K6162_RS28365 (99505) | 99505..99762 | - | 258 | WP_013214010.1 | hypothetical protein | - |
K6162_RS28370 (99891) | 99891..100004 | - | 114 | WP_014343462.1 | hypothetical protein | - |
K6162_RS28375 (100540) | 100540..101406 | + | 867 | WP_004118283.1 | replication initiation protein | - |
K6162_RS28380 (102516) | 102516..103721 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
K6162_RS28385 (103721) | 103721..104695 | + | 975 | WP_011977819.1 | ParB family protein | - |
K6162_RS28390 (104777) | 104777..106048 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
K6162_RS28395 (106048) | 106048..106479 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
K6162_RS28400 (106886) | 106886..108373 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
K6162_RS28405 (108622) | 108622..109593 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
K6162_RS28410 (109596) | 109596..110267 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
K6162_RS28415 (110330) | 110330..110560 | + | 231 | WP_001568040.1 | hypothetical protein | - |
K6162_RS29435 (110756) | 110756..110925 | + | 170 | Protein_148 | hypothetical protein | - |
K6162_RS28420 (110997) | 110997..111698 | + | 702 | WP_151488309.1 | DNA methylase | - |
K6162_RS28425 (111698) | 111698..111919 | + | 222 | WP_001568042.1 | hypothetical protein | - |
K6162_RS28430 (111929) | 111929..112348 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
K6162_RS28435 (112402) | 112402..113169 | + | 768 | WP_013214013.1 | hypothetical protein | - |
K6162_RS28440 (113850) | 113850..114278 | + | 429 | WP_001568045.1 | antirestriction protein | - |
K6162_RS28445 (114321) | 114321..114827 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
K6162_RS28450 (114870) | 114870..115061 | + | 192 | WP_001568047.1 | hypothetical protein | - |
K6162_RS28455 (115249) | 115249..115503 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
K6162_RS28460 (115538) | 115538..115858 | + | 321 | WP_001568049.1 | hypothetical protein | - |
K6162_RS28465 (116538) | 116538..116765 | + | 228 | WP_001568050.1 | hypothetical protein | - |
K6162_RS28470 (116857) | 116857..117087 | + | 231 | WP_001568051.1 | hypothetical protein | - |
K6162_RS28475 (117139) | 117139..118494 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
K6162_RS28480 (118542) | 118542..119105 | + | 564 | WP_014343514.1 | methyltransferase | - |
K6162_RS28485 (119938) | 119938..120480 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
K6162_RS28490 (120529) | 120529..120777 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
K6162_RS28495 (120847) | 120847..122904 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
K6162_RS28500 (122949) | 122949..123380 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
K6162_RS28505 (123377) | 123377..124105 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
K6162_RS28510 (124102) | 124102..124428 | + | 327 | WP_013023807.1 | hypothetical protein | - |
K6162_RS28515 (124484) | 124484..124858 | + | 375 | WP_014343510.1 | hypothetical protein | - |
K6162_RS29440 (125028) | 125028..125177 | + | 150 | Protein_169 | DUF5431 family protein | - |
K6162_RS28520 (125128) | 125128..125244 | + | 117 | WP_055313929.1 | type I toxin-antitoxin system Hok family toxin | - |
K6162_RS28525 (125937) | 125937..126209 | + | 273 | WP_040245921.1 | hypothetical protein | - |
K6162_RS28530 (126206) | 126206..126556 | + | 351 | WP_040245917.1 | hypothetical protein | - |
K6162_RS28535 (126571) | 126571..126888 | + | 318 | WP_014343505.1 | hypothetical protein | - |
K6162_RS28540 (127729) | 127729..128085 | + | 357 | WP_014343501.1 | hypothetical protein | - |
K6162_RS28545 (128146) | 128146..128358 | + | 213 | WP_014343500.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
---|