MGE detailed information
MGE type: Conjugative plasmid MGE length: 117749 bp
Accession: NZ_CP080174 Location: 1..117749 Organism: Escherichia coli strain PK8566 Replicon: plasmid pPK8566-117kb
Accession: NZ_CP080174 Location: 1..117749 Organism: Escherichia coli strain PK8566 Replicon: plasmid pPK8566-117kb
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZY09_RS24450 (46) | 46..1077 | + | 1032 | WP_000907875.1 | plasmid replication initiator RepA | - |
| KZY09_RS24455 (1985) | 1985..2254 | + | 270 | WP_000079928.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| KZY09_RS24460 (2254) | 2254..2532 | + | 279 | WP_001384452.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| KZY09_RS24465 (2617) | 2617..2964 | + | 348 | WP_219795695.1 | DUF6404 family protein | - |
| KZY09_RS24470 (2982) | 2982..3572 | - | 591 | WP_000194550.1 | hypothetical protein | - |
| KZY09_RS24475 (3572) | 3572..3826 | - | 255 | WP_000343103.1 | hypothetical protein | - |
| KZY09_RS24480 (4178) | 4178..5179 | + | 1002 | WP_000774874.1 | DUF4238 domain-containing protein | - |
| KZY09_RS24485 (5355) | 5355..5699 | - | 345 | WP_000793307.1 | hypothetical protein | - |
| KZY09_RS24490 (6285) | 6285..6989 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KZY09_RS24495 (7042) | 7042..7362 | - | 321 | Protein_9 | NAD(P)H-dependent oxidoreductase | - |
| KZY09_RS24500 (7523) | 7523..7846 | - | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KZY09_RS24505 (7951) | 7951..9030 | + | 1080 | WP_001089727.1 | permease | - |
| KZY09_RS24510 (9323) | 9323..9940 | - | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| KZY09_RS24515 (10132) | 10132..11688 | - | 1557 | WP_000818556.1 | AAA family ATPase | - |
| KZY09_RS24520 (11951) | 11951..12541 | - | 591 | WP_000194575.1 | hypothetical protein | - |
| KZY09_RS24525 (12541) | 12541..12798 | - | 258 | WP_000343085.1 | hypothetical protein | - |
| KZY09_RS24530 (13152) | 13152..15290 | + | 2139 | WP_000350638.1 | AAA family ATPase | - |
| KZY09_RS24535 (15452) | 15452..15868 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KZY09_RS24540 (15865) | 15865..16095 | - | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KZY09_RS24545 (16280) | 16280..16722 | - | 443 | Protein_19 | IS3 family transposase ISEc25 | Transposase |
| KZY09_RS26065 (16782) | 16782..17023 | + | 242 | Protein_20 | hypothetical protein | - |
| KZY09_RS24550 (17306) | 17306..18190 | - | 885 | WP_000942222.1 | helix-turn-helix domain-containing protein | - |
| KZY09_RS24555 (18631) | 18631..19305 | + | 675 | WP_232379284.1 | Multiple antibiotic resistance protein MarA | VF |
| KZY09_RS24560 (19350) | 19350..20099 | - | 750 | WP_106141716.1 | EAL domain-containing protein | - |
| KZY09_RS26070 (20436) | 20436..21665 | - | 1230 | WP_232379285.1 | hypothetical protein | - |
| KZY09_RS24570 (21685) | 21685..24297 | - | 2613 | WP_219795697.1 | Outer membrane usher protein FimD | VF |
| KZY09_RS24575 (24301) | 24301..25092 | - | 792 | WP_232379286.1 | molecular chaperone | - |
| KZY09_RS24580 (25037) | 25037..25738 | - | 702 | WP_089551190.1 | molecular chaperone | - |
| KZY09_RS24585 (25741) | 25741..26304 | - | 564 | WP_160515577.1 | fimbrial protein | - |
| KZY09_RS24590 (26336) | 26336..26893 | - | 558 | WP_160515576.1 | type 1 fimbrial protein | - |
| KZY09_RS24595 (26901) | 26901..27611 | - | 711 | WP_160515575.1 | Chaperone protein FocC | VF |
| KZY09_RS24600 (27678) | 27678..28217 | - | 540 | WP_228395587.1 | type 1 fimbrial protein | - |
| KZY09_RS24605 (28655) | 28655..29698 | + | 1044 | WP_000279209.1 | anaerobic sulfite reductase subunit AsrA | - |
| KZY09_RS24610 (29702) | 29702..30520 | + | 819 | WP_012565200.1 | anaerobic sulfite reductase subunit AsrB | - |
| KZY09_RS24615 (30531) | 30531..31544 | + | 1014 | WP_126633356.1 | sulfite reductase subunit C | - |
| KZY09_RS24620 (31738) | 31738..31914 | - | 177 | Protein_35 | transposase domain-containing protein | - |
| KZY09_RS24625 (31982) | 31982..32320 | - | 339 | WP_228395588.1 | group II intron maturase-specific domain-containing protein | - |
| KZY09_RS24630 (32415) | 32415..32665 | - | 251 | Protein_37 | Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase | VF |
| KZY09_RS26270 (32788) | 32788..33000 | - | 213 | WP_053285704.1 | FaeA/PapI family transcriptional regulator | - |
| KZY09_RS24640 (33306) | 33306..34523 | + | 1218 | Protein_39 | IS3 family transposase IS2 | Transposase |
| KZY09_RS24645 (34956) | 34956..35879 | - | 924 | WP_232379287.1 | hypothetical protein | - |
| KZY09_RS24650 (36411) | 36411..36679 | + | 269 | Protein_41 | type II toxin-antitoxin system ParD family antitoxin | - |
| KZY09_RS26080 (36666) | 36666..36956 | + | 291 | Protein_42 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KZY09_RS24660 (37482) | 37482..37895 | + | 414 | WP_000465043.1 | hypothetical protein | - |
| KZY09_RS24665 (37897) | 37897..38676 | + | 780 | WP_001164198.1 | site-specific integrase | - |
| KZY09_RS24670 (38855) | 38855..39499 | + | 645 | WP_001144036.1 | ParA family protein | - |
| KZY09_RS24675 (39586) | 39586..39894 | + | 309 | WP_000030199.1 | hypothetical protein | - |
| KZY09_RS24680 (40308) | 40308..41288 | + | 981 | WP_000688514.1 | plasmid segregation protein ParM | - |
| KZY09_RS24685 (41281) | 41281..41697 | + | 417 | WP_001278818.1 | plasmid partitioning/stability family protein | - |
| KZY09_RS24690 (41699) | 41699..42973 | - | 1275 | WP_000457492.1 | Y-family DNA polymerase | - |
| KZY09_RS24695 (42973) | 42973..43410 | - | 438 | Protein_50 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| KZY09_RS24700 (43407) | 43407..43655 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| KZY09_RS24705 (44073) | 44073..44975 | + | 903 | WP_077790361.1 | DUF1281 domain-containing protein | - |
| KZY09_RS24710 (44972) | 44972..45283 | + | 312 | WP_077064875.1 | hypothetical protein | - |
| KZY09_RS24715 (45359) | 45359..46042 | + | 684 | WP_000086148.1 | DNA methylase | - |
| KZY09_RS24720 (46043) | 46043..46264 | + | 222 | WP_001104879.1 | hypothetical protein | - |
| KZY09_RS24725 (46278) | 46278..46712 | + | 435 | WP_054170940.1 | DUF1380 family protein | - |
| KZY09_RS24730 (46758) | 46758..47534 | + | 777 | WP_219795699.1 | hypothetical protein | - |
| KZY09_RS24735 (47952) | 47952..48377 | + | 426 | WP_032072584.1 | antirestriction protein | - |
| KZY09_RS24740 (48424) | 48424..48846 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| KZY09_RS24745 (48843) | 48843..49034 | + | 192 | WP_001027500.1 | hypothetical protein | - |
| KZY09_RS24750 (49170) | 49170..49418 | + | 249 | WP_001354012.1 | hypothetical protein | - |
| KZY09_RS24755 (49802) | 49802..50329 | + | 528 | WP_021522654.1 | single-stranded DNA-binding protein | - |
| KZY09_RS24760 (50387) | 50387..50620 | + | 234 | WP_000006012.1 | DUF905 family protein | - |
| KZY09_RS24765 (50679) | 50679..52637 | + | 1959 | WP_219795701.1 | ParB/RepB/Spo0J family partition protein | - |
| KZY09_RS24770 (52692) | 52692..53126 | + | 435 | WP_000845897.1 | conjugation system SOS inhibitor PsiB | - |
| KZY09_RS24775 (53123) | 53123..53842 | + | 720 | WP_001276260.1 | plasmid SOS inhibition protein A | - |
| KZY09_RS24780 (53972) | 53972..55147 | + | 1176 | WP_000942657.1 | IS200-IS605 family transposase ISEc46 | Transposase |
| KZY09_RS24785 (55594) | 55594..56094 | + | 501 | WP_000117611.1 | antirestriction protein ArdA | - |
| KZY09_RS24790 (56823) | 56823..57257 | + | 435 | WP_000218863.1 | hypothetical protein | - |
| KZY09_RS24795 (57351) | 57351..57617 | + | 267 | WP_001247862.1 | hypothetical protein | - |
| KZY09_RS24800 (57682) | 57682..58584 | + | 903 | WP_000038404.1 | Recombination-promoting nuclease RpnA | VF |
| KZY09_RS24805 (58584) | 58584..58877 | + | 294 | WP_077250487.1 | hypothetical protein | VF |
| KZY09_RS24810 (58908) | 58908..59159 | - | 252 | WP_000148286.1 | helix-turn-helix transcriptional regulator | - |
| KZY09_RS24815 (59740) | 59740..60588 | + | 849 | WP_001077027.1 | DUF4942 domain-containing protein | - |
| KZY09_RS24820 (60674) | 60674..61009 | - | 336 | WP_000157086.1 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| KZY09_RS24825 (61243) | 61243..61575 | + | 333 | WP_001283947.1 | IncI1-type relaxosome accessory protein NikA | - |
| KZY09_RS24830 (61586) | 61586..64285 | + | 2700 | WP_001474686.1 | Protein TraI | Relaxase |
| KZY09_RS24835 (64322) | 64322..66613 | - | 2292 | WP_001289271.1 | F-type conjugative transfer protein TrbC | - |
| KZY09_RS24840 (66606) | 66606..67676 | - | 1071 | WP_000151575.1 | IncI1-type conjugal transfer protein TrbB | - |
| KZY09_RS24845 (67695) | 67695..68903 | - | 1209 | WP_000121273.1 | IncI1-type conjugal transfer protein TrbA | - |
| - (69083) | 69083..69145 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (69083) | 69083..69145 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (69083) | 69083..69145 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (69083) | 69083..69145 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| KZY09_RS24850 (69195) | 69195..69347 | + | 153 | WP_001303307.1 | Hok/Gef family protein | Toxin Detail |
| KZY09_RS24855 (69419) | 69419..69670 | - | 252 | WP_001291965.1 | hypothetical protein | - |
| - (70057) | 70057..70108 | - | 52 | NuclAT_1 | - | - |
| - (70057) | 70057..70108 | - | 52 | NuclAT_1 | - | - |
| - (70057) | 70057..70108 | - | 52 | NuclAT_1 | - | - |
| - (70057) | 70057..70108 | - | 52 | NuclAT_1 | - | - |
| KZY09_RS24860 (70824) | 70824..72052 | + | 1229 | WP_088895425.1 | IS3 family transposase IS2 | Transposase |
| KZY09_RS24865 (72498) | 72498..72707 | + | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
| KZY09_RS24870 (72779) | 72779..73441 | - | 663 | WP_000644794.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| KZY09_RS24875 (73512) | 73512..75680 | - | 2169 | WP_061583910.1 | DotA/TraY family protein | - |
| KZY09_RS24880 (75777) | 75777..76361 | - | 585 | WP_001037998.1 | conjugal transfer protein TraX | - |
| KZY09_RS24885 (76390) | 76390..77592 | - | 1203 | WP_001189158.1 | IncI1-type conjugal transfer protein TraW | - |
| KZY09_RS24890 (77559) | 77559..78173 | - | 615 | WP_000337394.1 | IncI1-type conjugal transfer protein TraV | - |
| KZY09_RS24895 (78173) | 78173..81217 | - | 3045 | WP_001024752.1 | IncI1-type conjugal transfer protein TraU | - |
| KZY09_RS24900 (81307) | 81307..82107 | - | 801 | WP_001164788.1 | IncI1-type conjugal transfer protein TraT | - |
| KZY09_RS24905 (82091) | 82091..82279 | - | 189 | WP_001277255.1 | putative conjugal transfer protein TraS | - |
| KZY09_RS24910 (82343) | 82343..82747 | - | 405 | WP_000086960.1 | IncI1-type conjugal transfer protein TraR | - |
| KZY09_RS24915 (82798) | 82798..83325 | - | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| KZY09_RS24920 (83325) | 83325..84029 | - | 705 | WP_000801920.1 | IncI1-type conjugal transfer protein TraP | - |
| KZY09_RS24925 (84029) | 84029..85318 | - | 1290 | WP_001271997.1 | conjugal transfer protein TraO | - |
| KZY09_RS24930 (85321) | 85321..86304 | - | 984 | WP_001191878.1 | hypothetical protein | VF |
| KZY09_RS24935 (86315) | 86315..86929 | - | 615 | WP_000813801.1 | DotI/IcmL family type IV secretion protein | - |
| KZY09_RS24940 (87004) | 87004..87351 | - | 348 | WP_001055900.1 | conjugal transfer protein | - |
| KZY09_RS24945 (87369) | 87369..91136 | - | 3768 | WP_001141535.1 | DUF5710 domain-containing protein | - |
| KZY09_RS24950 (91226) | 91226..91777 | - | 552 | WP_000014584.1 | Phospholipase D | VF |
| KZY09_RS24955 (91792) | 91792..92082 | - | 291 | WP_001299214.1 | hypothetical protein | - |
| KZY09_RS24960 (92079) | 92079..93227 | - | 1149 | WP_001024972.1 | putative protein YggR | VF |
| KZY09_RS24965 (93224) | 93224..94042 | - | 819 | WP_000646097.1 | hypothetical protein | VF |
| KZY09_RS24970 (94039) | 94039..94497 | - | 459 | WP_001079808.1 | hypothetical protein | VF |
| KZY09_RS24975 (94892) | 94892..95476 | - | 585 | WP_000977522.1 | histidine phosphatase family protein | - |
| KZY09_RS24980 (95536) | 95536..96738 | - | 1203 | WP_000976351.1 | conjugal transfer protein TraF | - |
| KZY09_RS24985 (96823) | 96823..97080 | - | 258 | Protein_108 | conjugal transfer protein TraE | - |
| KZY09_RS24990 (97135) | 97135..98103 | - | 969 | WP_000654811.1 | IS5 family transposase IS903B | Transposase |
| KZY09_RS24995 (98134) | 98134..98712 | - | 579 | Protein_110 | conjugal transfer protein TraE | - |
| KZY09_RS25000 (98863) | 98863..100017 | - | 1155 | WP_001139958.1 | site-specific integrase | - |
| KZY09_RS25005 (101303) | 101303..102727 | - | 1425 | WP_001389385.1 | hypothetical protein | VF |
| KZY09_RS25010 (102727) | 102727..103383 | - | 657 | WP_001193554.1 | hypothetical protein | VF |
| KZY09_RS25015 (103368) | 103368..103928 | - | 561 | WP_000014116.1 | hypothetical protein | VF |
| KZY09_RS25020 (103938) | 103938..104552 | - | 615 | WP_000959785.1 | hypothetical protein | VF |
| KZY09_RS25025 (104570) | 104570..105667 | - | 1098 | WP_001208805.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| KZY09_RS25030 (105680) | 105680..107233 | - | 1554 | WP_000362202.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| KZY09_RS25035 (107244) | 107244..107696 | - | 453 | WP_001247334.1 | hypothetical protein | VF |
| KZY09_RS25040 (107683) | 107683..108978 | - | 1296 | WP_000752774.1 | type 4b pilus protein PilO2 | - |
| KZY09_RS25045 (108971) | 108971..110653 | - | 1683 | WP_000748143.1 | Outer membrane lipoprotein BfpB | VF |
| KZY09_RS25050 (110667) | 110667..111104 | - | 438 | WP_000539807.1 | hypothetical protein | VF |
| KZY09_RS25055 (111104) | 111104..112171 | - | 1068 | WP_219795693.1 | hypothetical protein | VF |
| KZY09_RS25060 (112845) | 112845..113297 | - | 453 | WP_000008893.1 | hypothetical protein | - |
| KZY09_RS25065 (113340) | 113340..113594 | - | 255 | WP_001136192.1 | PilI type IV pilus biogenesis protein | - |
| KZY09_RS25070 (113862) | 113862..114428 | - | 567 | WP_000776428.1 | protein TraD | - |
| KZY09_RS25075 (114442) | 114442..115125 | - | 684 | WP_000213857.1 | conjugal transfer protein TraC | - |
| KZY09_RS25080 (115379) | 115379..115912 | - | 534 | WP_001303319.1 | transcription termination/antitermination NusG family protein | - |
| KZY09_RS25085 (116354) | 116354..116641 | - | 288 | WP_000074849.1 | conjugal transfer protein TraA | - |
| KZY09_RS25090 (116559) | 116559..116789 | - | 231 | WP_228772074.1 | ash family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|