MGE detailed information
MGE type: Conjugative plasmid MGE length: 156326 bp
Accession: NZ_CP080127 Location: 1..156326 Organism: Escherichia coli strain PK8568 Replicon: plasmid pPK8568-156kb
Accession: NZ_CP080127 Location: 1..156326 Organism: Escherichia coli strain PK8568 Replicon: plasmid pPK8568-156kb
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZY03_RS22625 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| KZY03_RS22630 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| KZY03_RS22635 (2124) | 2124..2312 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| KZY03_RS22640 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| KZY03_RS22645 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| KZY03_RS22650 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| KZY03_RS22655 (7449) | 7449..7628 | - | 180 | Protein_6 | integrase core domain-containing protein | - |
| KZY03_RS22660 (7767) | 7767..8057 | + | 291 | Protein_7 | IS3 family transposase IS1203 | Transposase |
| KZY03_RS22665 (8240) | 8240..8986 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| KZY03_RS22670 (9001) | 9001..10542 | - | 1542 | WP_001518966.1 | IS21 family transposase ISEc12 | Transposase |
| KZY03_RS22675 (10723) | 10723..11408 | + | 686 | WP_232379266.1 | IS1 family transposase IS1G | Transposase |
| KZY03_RS22680 (11402) | 11402..11683 | - | 282 | WP_072834405.1 | hypothetical protein | - |
| KZY03_RS22685 (11824) | 11824..13650 | - | 1827 | WP_001339650.1 | AAA family ATPase | - |
| KZY03_RS22690 (13653) | 13653..14138 | - | 486 | WP_001015823.1 | hypothetical protein | - |
| KZY03_RS22695 (14128) | 14128..15228 | - | 1101 | WP_072714138.1 | hypothetical protein | - |
| KZY03_RS22700 (15758) | 15758..15907 | - | 150 | Protein_15 | IS3 family transposase IS2 | Transposase |
| KZY03_RS22705 (16085) | 16085..17278 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| KZY03_RS22715 (20356) | 20356..20649 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| KZY03_RS22720 (20707) | 20707..20906 | - | 200 | Protein_19 | lysis protein | - |
| KZY03_RS22725 (21460) | 21460..22487 | + | 1028 | Protein_20 | integrase core domain-containing protein | - |
| KZY03_RS22730 (23798) | 23798..24913 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| KZY03_RS22735 (25053) | 25053..28712 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| KZY03_RS22740 (28816) | 28816..30045 | + | 1230 | WP_001552738.1 | Enterochelin esterase | VF |
| KZY03_RS22745 (30130) | 30130..31086 | + | 957 | WP_000271276.1 | Ferri-bacillibactin esterase BesA | VF |
| KZY03_RS22750 (31131) | 31131..33308 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| KZY03_RS22760 (34392) | 34392..34466 | - | 75 | Protein_27 | colicin | - |
| KZY03_RS22765 (34444) | 34444..34680 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| KZY03_RS22770 (35222) | 35222..35425 | - | 204 | Protein_29 | hypothetical protein | - |
| KZY03_RS22775 (35598) | 35598..35765 | + | 168 | Protein_30 | colicin-B | - |
| KZY03_RS22780 (35783) | 35783..36310 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| KZY03_RS22785 (36554) | 36554..37369 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| KZY03_RS22790 (37419) | 37419..37772 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| KZY03_RS22795 (37950) | 37950..38741 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| KZY03_RS22800 (38738) | 38738..39427 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| KZY03_RS22805 (39471) | 39471..39821 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| KZY03_RS22810 (40397) | 40397..40627 | + | 231 | WP_001261276.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KZY03_RS22815 (40624) | 40624..41040 | + | 417 | WP_000754566.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KZY03_RS22820 (41244) | 41244..42100 | + | 857 | Protein_39 | IS3 family transposase ISEc15 | Transposase |
| KZY03_RS22825 (42382) | 42382..43458 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| KZY03_RS22830 (43475) | 43475..43753 | + | 279 | Protein_41 | IS3 family transposase | - |
| KZY03_RS22835 (43861) | 43861..45936 | - | 2076 | WP_061350058.1 | protease Lon-related BREX system protein BrxL | - |
| KZY03_RS22840 (45953) | 45953..48625 | - | 2673 | WP_061350059.1 | BREX-1 system phosphatase PglZ type A | - |
| KZY03_RS22845 (48625) | 48625..52293 | - | 3669 | WP_061350060.1 | BREX-1 system adenine-specific DNA-methyltransferase PglX | - |
| KZY03_RS22850 (52309) | 52309..54072 | - | 1764 | WP_061350061.1 | DUF262 domain-containing protein | - |
| KZY03_RS22855 (54089) | 54089..57766 | - | 3678 | WP_054528932.1 | BREX system P-loop protein BrxC | - |
| KZY03_RS22860 (57785) | 57785..58369 | - | 585 | WP_010129448.1 | DUF1788 domain-containing protein | - |
| KZY03_RS22865 (58366) | 58366..58965 | - | 600 | WP_001698871.1 | DUF1819 family protein | - |
| KZY03_RS22870 (58975) | 58975..59901 | - | 927 | WP_006788197.1 | WYL domain-containing protein | - |
| KZY03_RS25365 (60160) | 60160..60291 | - | 132 | WP_265326151.1 | hypothetical protein | - |
| KZY03_RS22875 (60230) | 60230..60918 | + | 689 | WP_232379267.1 | IS1 family transposase IS1X3 | Transposase |
| KZY03_RS22880 (61126) | 61126..61437 | - | 312 | Protein_52 | formamidase | - |
| KZY03_RS22885 (61470) | 61470..62438 | + | 969 | WP_001348255.1 | IS5 family transposase IS903 | Transposase |
| KZY03_RS22890 (62807) | 62807..63940 | - | 1134 | WP_011117364.1 | permease | - |
| KZY03_RS22895 (64045) | 64045..64368 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KZY03_RS22900 (64469) | 64469..65179 | + | 711 | WP_113852413.1 | arsenical resistance protein ArsH | - |
| KZY03_RS22905 (65188) | 65188..65733 | + | 546 | WP_219805133.1 | sigma-70 family RNA polymerase sigma factor | - |
| KZY03_RS22910 (65809) | 65809..66171 | + | 363 | WP_011117366.1 | arsenic metallochaperone ArsD family protein | - |
| KZY03_RS22915 (66192) | 66192..67949 | + | 1758 | WP_100752807.1 | Arsenical pump-driving ATPase | VF |
| KZY03_RS22920 (67981) | 67981..68406 | - | 426 | WP_011117598.1 | glutaredoxin-dependent arsenate reductase | - |
| KZY03_RS22925 (68419) | 68419..69708 | - | 1290 | WP_100752805.1 | arsenite efflux transporter membrane subunit ArsB | - |
| KZY03_RS22930 (69757) | 69757..71508 | - | 1752 | WP_096969194.1 | arsenite efflux transporter ATPase subunit ArsA | - |
| KZY03_RS22935 (71526) | 71526..71888 | - | 363 | WP_100752803.1 | arsenite efflux transporter metallochaperone ArsD | - |
| KZY03_RS22940 (71936) | 71936..72289 | - | 354 | WP_100752801.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| KZY03_RS25110 (72381) | 72381..72658 | - | 278 | Protein_65 | hypothetical protein | - |
| KZY03_RS22950 (73573) | 73573..74430 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| KZY03_RS25115 (74423) | 74423..74470 | - | 48 | WP_077822033.1 | hypothetical protein | - |
| KZY03_RS25120 (74461) | 74461..74697 | + | 237 | WP_223368648.1 | replication protein RepA | - |
| KZY03_RS22960 (74723) | 74723..74983 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| KZY03_RS22965 (75222) | 75222..75795 | - | 574 | Protein_70 | DUF2726 domain-containing protein | - |
| KZY03_RS22970 (75833) | 75833..76042 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| KZY03_RS22975 (76088) | 76088..76549 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| KZY03_RS22980 (76792) | 76792..77004 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| KZY03_RS22985 (77142) | 77142..77702 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| KZY03_RS22990 (77757) | 77757..78503 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| KZY03_RS22995 (78523) | 78523..83793 | - | 5271 | WP_011117356.1 | Multifunctional conjugation protein TraI | Relaxase |
| KZY03_RS23000 (83875) | 83875..84102 | + | 228 | WP_000450532.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| KZY03_RS23005 (84102) | 84102..84500 | + | 399 | WP_000911324.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KZY03_RS23010 (84509) | 84509..86662 | - | 2154 | WP_000009350.1 | type IV conjugative transfer system coupling protein TraD | - |
| KZY03_RS23015 (86915) | 86915..87646 | - | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| KZY03_RS23020 (87671) | 87671..88192 | - | 522 | WP_000632670.1 | conjugal transfer entry exclusion protein TraS | - |
| KZY03_RS23025 (88225) | 88225..91041 | - | 2817 | WP_001007054.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KZY03_RS23030 (91038) | 91038..92411 | - | 1374 | WP_021553026.1 | conjugal transfer pilus assembly protein TraH | - |
| KZY03_RS23035 (92398) | 92398..92792 | - | 395 | Protein_84 | F-type conjugal transfer protein TrbF | - |
| KZY03_RS23040 (92779) | 92779..93120 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| KZY03_RS23045 (93050) | 93050..93595 | - | 546 | WP_000059850.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KZY03_RS23050 (93582) | 93582..93866 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KZY03_RS23055 (93947) | 93947..94261 | + | 315 | WP_000415567.1 | hypothetical protein | - |
| KZY03_RS23060 (94263) | 94263..94610 | - | 348 | WP_001287913.1 | conjugal transfer protein TrbA | - |
| KZY03_RS23065 (94626) | 94626..95369 | - | 744 | WP_001030367.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KZY03_RS23070 (95362) | 95362..95619 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| KZY03_RS23075 (95646) | 95646..97454 | - | 1809 | WP_000821847.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KZY03_RS23080 (97451) | 97451..98089 | - | 639 | WP_011117354.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KZY03_RS23085 (98098) | 98098..99090 | - | 993 | WP_000830187.1 | conjugal transfer pilus assembly protein TraU | - |
| KZY03_RS23090 (99087) | 99087..99719 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| KZY03_RS23095 (99716) | 99716..100102 | - | 387 | WP_000097319.1 | type-F conjugative transfer system protein TrbI | - |
| KZY03_RS23100 (100099) | 100099..102726 | - | 2628 | WP_001064247.1 | type IV secretion system protein TraC | - |
| KZY03_RS23105 (102886) | 102886..103107 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| KZY03_RS23110 (103242) | 103242..103757 | - | 516 | WP_000809841.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KZY03_RS23115 (103754) | 103754..104005 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| KZY03_RS23120 (104017) | 104017..104214 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| KZY03_RS23125 (104201) | 104201..104791 | - | 591 | WP_000002792.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KZY03_RS23130 (104781) | 104781..106208 | - | 1428 | WP_011117353.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KZY03_RS23135 (106208) | 106208..106936 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| KZY03_RS23140 (106923) | 106923..107489 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| KZY03_RS23145 (107511) | 107511..107822 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KZY03_RS23150 (107837) | 107837..108202 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| KZY03_RS23155 (108235) | 108235..108636 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| KZY03_RS23160 (108729) | 108729..109418 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| KZY03_RS23165 (109605) | 109605..109988 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KZY03_RS23170 (110309) | 110309..110911 | + | 603 | WP_000243709.1 | hypothetical protein | VF |
| KZY03_RS23175 (111208) | 111208..112029 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| KZY03_RS23180 (112151) | 112151..112438 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| KZY03_RS23185 (112463) | 112463..112669 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| KZY03_RS25125 (112739) | 112739..112912 | + | 174 | Protein_115 | hypothetical protein | - |
| KZY03_RS23190 (113173) | 113173..114753 | - | 1581 | Protein_116 | PAS domain-containing methyl-accepting chemotaxis protein | - |
| KZY03_RS23195 (115018) | 115018..115269 | + | 252 | Protein_117 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| KZY03_RS23200 (115334) | 115334..116038 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KZY03_RS23205 (116092) | 116092..116442 | + | 351 | Protein_119 | DUF3363 domain-containing protein | - |
| KZY03_RS23210 (116659) | 116659..117873 | + | 1215 | WP_000214121.1 | Bicyclomycin resistance protein | ARG |
| KZY03_RS23215 (117901) | 117901..118206 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| KZY03_RS23220 (118318) | 118318..118506 | + | 189 | Protein_122 | IS91 family transposase | - |
| KZY03_RS23225 (118473) | 118473..119672 | - | 1200 | WP_000804063.1 | Tetracycline resistance protein, class C | ARG |
| KZY03_RS23230 (119778) | 119778..120428 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| KZY03_RS23235 (120493) | 120493..123498 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KZY03_RS23240 (123660) | 123660..124217 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KZY03_RS23245 (124400) | 124400..125260 | + | 861 | WP_015058868.1 | Beta-lactamase TEM | ARG |
| KZY03_RS23250 (125408) | 125408..125755 | - | 348 | Protein_128 | IS6 family transposase IS15DII | Transposase |
| KZY03_RS23255 (126002) | 126002..126475 | - | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| KZY03_RS23260 (126631) | 126631..127743 | + | 1113 | WP_024166810.1 | IS91 family transposase ISAzo26 | Transposase |
| KZY03_RS23265 (127689) | 127689..128393 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KZY03_RS23270 (128458) | 128458..128802 | + | 345 | Protein_132 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| KZY03_RS23275 (128806) | 128806..131772 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| KZY03_RS25130 (131749) | 131749..131967 | - | 219 | WP_071780187.1 | hypothetical protein | - |
| KZY03_RS23280 (132187) | 132187..132312 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KZY03_RS25135 (132254) | 132254..132403 | - | 150 | Protein_136 | plasmid maintenance protein Mok | - |
| - (132389) | 132389..132613 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (132389) | 132389..132613 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (132389) | 132389..132613 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (132389) | 132389..132613 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| KZY03_RS23285 (132425) | 132425..132613 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| KZY03_RS23290 (132582) | 132582..133344 | - | 763 | Protein_138 | plasmid SOS inhibition protein A | - |
| KZY03_RS23295 (133341) | 133341..133775 | - | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| KZY03_RS23300 (133830) | 133830..135788 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| KZY03_RS23305 (135847) | 135847..136080 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| KZY03_RS23310 (136136) | 136136..136663 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| KZY03_RS25140 (136982) | 136982..137235 | + | 254 | Protein_143 | hypothetical protein | - |
| KZY03_RS23320 (137459) | 137459..137641 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| KZY03_RS23325 (137641) | 137641..138102 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| KZY03_RS23330 (138102) | 138102..138527 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| KZY03_RS23335 (138929) | 138929..139693 | + | 765 | Protein_147 | IS110 family transposase ISEc32 | Transposase |
| KZY03_RS23345 (140455) | 140455..140790 | - | 336 | WP_000343070.1 | hypothetical protein | - |
| KZY03_RS23350 (140859) | 140859..141206 | - | 348 | WP_001350917.1 | hypothetical protein | - |
| KZY03_RS25145 (141203) | 141203..141372 | - | 170 | Protein_151 | hypothetical protein | - |
| KZY03_RS23355 (142138) | 142138..143109 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| KZY03_RS23360 (143109) | 143109..144275 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| KZY03_RS23370 (145428) | 145428..146930 | - | 1503 | WP_000715078.1 | hypothetical protein | - |
| KZY03_RS23375 (147566) | 147566..147991 | - | 426 | WP_012300440.1 | hypothetical protein | - |
| KZY03_RS23380 (148133) | 148133..148612 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| KZY03_RS23385 (149052) | 149052..149303 | + | 252 | WP_013362826.1 | hypothetical protein | - |
| KZY03_RS23390 (149276) | 149276..149407 | - | 132 | Protein_159 | phosphopyruvate hydratase | - |
| KZY03_RS23395 (149405) | 149405..149662 | + | 258 | Protein_160 | Tn3 family transposase | - |
| KZY03_RS23400 (149896) | 149896..150753 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| KZY03_RS23405 (150750) | 150750..151607 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| KZY03_RS23410 (151604) | 151604..152431 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| KZY03_RS23415 (152431) | 152431..153345 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| KZY03_RS23420 (153701) | 153701..154398 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| KZY03_RS23425 (154578) | 154578..155091 | - | 514 | Protein_166 | DUF4113 domain-containing protein | - |
| KZY03_RS23430 (155152) | 155152..155256 | - | 105 | Protein_167 | AAA family ATPase | - |
| KZY03_RS23435 (155258) | 155258..155581 | - | 324 | Protein_168 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|