MGE detailed information
MGE type: Conjugative plasmid MGE length: 77995 bp
Accession: NZ_CP076283 Location: 1..77995 Organism: Escherichia coli strain 442/2 Replicon: plasmid p4422IncF
Accession: NZ_CP076283 Location: 1..77995 Organism: Escherichia coli strain 442/2 Replicon: plasmid p4422IncF
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A7A15_RS23560 (6) | 6..404 | + | 399 | WP_000911317.1 | type II toxin-antitoxin system VapC family toxin | - |
| A7A15_RS23565 (413) | 413..2566 | - | 2154 | WP_021534620.1 | type IV conjugative transfer system coupling protein TraD | - |
| A7A15_RS23570 (2819) | 2819..3529 | - | 711 | WP_042032882.1 | conjugal transfer complement resistance protein TraT | - |
| A7A15_RS23575 (3575) | 3575..4096 | - | 522 | WP_096843900.1 | conjugal transfer entry exclusion protein TraS | - |
| A7A15_RS23580 (4129) | 4129..6945 | - | 2817 | WP_001007052.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| A7A15_RS23585 (6942) | 6942..8315 | - | 1374 | WP_000944319.1 | conjugal transfer pilus assembly protein TraH | - |
| A7A15_RS23590 (8302) | 8302..8694 | - | 393 | WP_001208952.1 | F-type conjugal transfer protein TrbF | - |
| A7A15_RS23595 (8681) | 8681..9022 | - | 342 | WP_001406994.1 | P-type conjugative transfer protein TrbJ | - |
| A7A15_RS23600 (8952) | 8952..9497 | - | 546 | WP_000059833.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| A7A15_RS23605 (9484) | 9484..9768 | - | 285 | WP_000624103.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| A7A15_RS23610 (9849) | 9849..10124 | + | 276 | WP_001513501.1 | hypothetical protein | - |
| A7A15_RS23615 (10126) | 10126..10473 | - | 348 | WP_021534621.1 | conjugal transfer protein TrbA | - |
| A7A15_RS23620 (10489) | 10489..11232 | - | 744 | WP_001030388.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| A7A15_RS23625 (11225) | 11225..11482 | - | 258 | WP_000864346.1 | conjugal transfer protein TrbE | - |
| A7A15_RS23630 (11509) | 11509..13317 | - | 1809 | WP_000821074.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| A7A15_RS23635 (13314) | 13314..13952 | - | 639 | WP_001406992.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| A7A15_RS23640 (13961) | 13961..14953 | - | 993 | WP_000830186.1 | conjugal transfer pilus assembly protein TraU | - |
| A7A15_RS23645 (14950) | 14950..15582 | - | 633 | WP_001203716.1 | type-F conjugative transfer system protein TraW | - |
| A7A15_RS23650 (15579) | 15579..15965 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| A7A15_RS23655 (15962) | 15962..18589 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| A7A15_RS23660 (18749) | 18749..18970 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| A7A15_RS23665 (19105) | 19105..19620 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| A7A15_RS23670 (19617) | 19617..19868 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| A7A15_RS23675 (19880) | 19880..20077 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| A7A15_RS23680 (20064) | 20064..20654 | - | 591 | WP_000002791.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| A7A15_RS23685 (20644) | 20644..22071 | - | 1428 | WP_000146689.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| A7A15_RS23690 (22071) | 22071..22799 | - | 729 | WP_021534622.1 | type-F conjugative transfer system secretin TraK | - |
| A7A15_RS23695 (22786) | 22786..23352 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| A7A15_RS23700 (23374) | 23374..23685 | - | 312 | WP_000012110.1 | type IV conjugative transfer system protein TraL | - |
| A7A15_RS23705 (23700) | 23700..24065 | - | 366 | WP_000340267.1 | type IV conjugative transfer system pilin TraA | - |
| A7A15_RS23710 (24099) | 24099..24326 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| A7A15_RS23715 (24420) | 24420..25106 | - | 687 | WP_000332492.1 | PAS domain-containing protein | - |
| A7A15_RS23720 (25296) | 25296..25679 | - | 384 | WP_000124980.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| A7A15_RS23725 (26035) | 26035..26637 | + | 603 | WP_000243717.1 | hypothetical protein | VF |
| A7A15_RS23730 (26932) | 26932..27753 | - | 822 | WP_001234477.1 | DUF932 domain-containing protein | - |
| A7A15_RS23735 (27870) | 27870..28157 | - | 288 | WP_000107547.1 | hypothetical protein | - |
| A7A15_RS23740 (28457) | 28457..28763 | + | 307 | Protein_37 | hypothetical protein | - |
| A7A15_RS23745 (29056) | 29056..29175 | - | 120 | WP_229484968.1 | Hok/Gef family protein | Toxin Detail |
| A7A15_RS23750 (29123) | 29123..29275 | - | 153 | Protein_39 | FlmC family protein | - |
| - (29263) | 29263..29479 | - | 217 | NuclAT_0 | - | Antitoxin Detail |
| - (29263) | 29263..29479 | - | 217 | NuclAT_0 | - | Antitoxin Detail |
| - (29263) | 29263..29479 | - | 217 | NuclAT_0 | - | Antitoxin Detail |
| - (29263) | 29263..29479 | - | 217 | NuclAT_0 | - | Antitoxin Detail |
| A7A15_RS23755 (29448) | 29448..30210 | - | 763 | Protein_40 | plasmid SOS inhibition protein A | - |
| A7A15_RS23760 (30207) | 30207..30614 | - | 408 | WP_001261250.1 | conjugation system SOS inhibitor PsiB | - |
| A7A15_RS23765 (30775) | 30775..30954 | + | 180 | WP_000618107.1 | hypothetical protein | - |
| A7A15_RS23770 (31038) | 31038..31430 | - | 393 | WP_000272016.1 | plasmid partitioning/stability family protein | - |
| A7A15_RS23775 (31434) | 31434..32408 | - | 975 | WP_021534625.1 | plasmid segregation protein ParM | - |
| A7A15_RS23780 (32647) | 32647..33021 | - | 375 | WP_000752650.1 | hypothetical protein | - |
| A7A15_RS23785 (33021) | 33021..33653 | - | 633 | WP_000312330.1 | ParA family protein | - |
| A7A15_RS23790 (34501) | 34501..35256 | - | 756 | WP_000807693.1 | replication initiation protein RepE | - |
| A7A15_RS23795 (35813) | 35813..36463 | - | 651 | Protein_48 | site-specific integrase | - |
| A7A15_RS23800 (36512) | 36512..36875 | + | 364 | Protein_49 | zinc ribbon domain-containing protein | - |
| A7A15_RS23805 (36889) | 36889..36957 | - | 69 | WP_211180522.1 | protein YkiE | - |
| A7A15_RS23810 (37094) | 37094..37615 | + | 522 | WP_001283623.1 | putative RNA polymerase sigma factor FecI | VF |
| A7A15_RS23815 (37612) | 37612..38565 | + | 954 | WP_001068902.1 | ferric citrate uptake sigma factor regulator FecR | - |
| A7A15_RS23820 (38652) | 38652..40976 | + | 2325 | WP_021534628.1 | TonB-dependent Fe(3+) dicitrate receptor FecA | - |
| A7A15_RS23825 (41021) | 41021..41108 | + | 88 | Protein_54 | hypothetical protein | - |
| A7A15_RS23830 (41179) | 41179..41451 | + | 273 | WP_000019163.1 | hypothetical protein | - |
| A7A15_RS23835 (41432) | 41432..42082 | + | 651 | Protein_56 | IS91 family transposase ISSbo1 | Transposase |
| A7A15_RS23840 (42141) | 42141..42358 | - | 218 | Protein_57 | transposase | - |
| A7A15_RS23845 (42359) | 42359..42889 | - | 531 | WP_000348884.1 | GNAT family N-acetyltransferase | Toxin Detail |
| A7A15_RS23850 (42893) | 42893..43162 | - | 270 | WP_001275013.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| A7A15_RS23855 (44050) | 44050..45039 | + | 990 | WP_024201093.1 | RepB family plasmid replication initiator protein | - |
| A7A15_RS23860 (45322) | 45322..46062 | - | 741 | WP_021534629.1 | tyrosine-type recombinase/integrase | - |
| A7A15_RS23865 (46183) | 46183..46317 | - | 135 | Protein_62 | serine/threonine protein kinase | - |
| A7A15_RS23870 (46814) | 46814..48313 | - | 1500 | WP_001263872.1 | alpha/beta hydrolase | - |
| A7A15_RS23875 (48406) | 48406..49353 | - | 948 | WP_001407138.1 | Outer membrane protease OmpP | VF |
| A7A15_RS23880 (50606) | 50606..51826 | + | 1221 | WP_000040078.1 | autotransporter strand-loop-strand O-heptosyltransferase | - |
| A7A15_RS23885 (51819) | 51819..56627 | + | 4809 | WP_257122355.1 | putative autotransporter | VF |
| A7A15_RS23890 (56925) | 56925..57203 | + | 279 | WP_042054335.1 | hypothetical protein | - |
| A7A15_RS23895 (57378) | 57378..57654 | - | 277 | Protein_68 | transposase | - |
| A7A15_RS23900 (58060) | 58060..58896 | - | 837 | WP_021534617.1 | Right origin-binding protein | VF |
| A7A15_RS23905 (59211) | 59211..60242 | - | 1032 | Protein_70 | IS3 family transposase | - |
| A7A15_RS23910 (60643) | 60643..61657 | + | 1015 | Protein_71 | integrase core domain-containing protein | - |
| A7A15_RS23920 (62458) | 62458..63405 | + | 948 | WP_001253824.1 | DMT family transporter | - |
| A7A15_RS23925 (63746) | 63746..63901 | + | 156 | Protein_73 | IS110 family transposase | - |
| A7A15_RS23930 (64297) | 64297..64548 | - | 252 | WP_001315600.1 | HTH domain-containing protein | - |
| A7A15_RS23935 (65898) | 65898..66755 | - | 858 | WP_000131011.1 | incFII family plasmid replication initiator RepA | - |
| A7A15_RS23940 (66748) | 66748..66822 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| A7A15_RS23945 (66871) | 66871..66996 | + | 126 | WP_071590472.1 | replication protein RepA | - |
| A7A15_RS23950 (67069) | 67069..67317 | - | 249 | WP_000083838.1 | replication regulatory protein RepA | - |
| A7A15_RS23955 (67601) | 67601..67750 | - | 150 | WP_001300273.1 | Hok/Gef family protein | Toxin Detail |
| - (67794) | 67794..67855 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (67794) | 67794..67855 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (67794) | 67794..67855 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (67794) | 67794..67855 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| A7A15_RS23960 (68515) | 68515..68976 | - | 462 | WP_000760077.1 | thermonuclease family protein | - |
| A7A15_RS23965 (69719) | 69719..69922 | - | 204 | WP_001327131.1 | hypothetical protein | - |
| A7A15_RS23970 (70077) | 70077..70634 | - | 558 | WP_000139319.1 | fertility inhibition protein FinO | - |
| A7A15_RS23975 (70737) | 70737..71597 | - | 861 | WP_000704512.1 | putative protein YcjY | VF |
| A7A15_RS23980 (71656) | 71656..72402 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| A7A15_RS23985 (72422) | 72422..77692 | - | 5271 | WP_096843899.1 | Multifunctional conjugation protein TraI | Relaxase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|