MGE detailed information
MGE type: Conjugative plasmid MGE length: 133041 bp
Accession: NZ_CP075641 Location: 1..133041 Organism: Escherichia coli strain S19-141 Replicon: plasmid pS19_141-a
Accession: NZ_CP075641 Location: 1..133041 Organism: Escherichia coli strain S19-141 Replicon: plasmid pS19_141-a
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JFX59_RS24450 (1) | 1..978 | + | 978 | WP_001369978.1 | RepB family plasmid replication initiator protein | - |
| JFX59_RS24455 (1217) | 1217..1499 | - | 283 | Protein_1 | ISL3 family transposase ISEc53 | Transposase |
| JFX59_RS24460 (1656) | 1656..1886 | - | 231 | WP_032279745.1 | hypothetical protein | - |
| JFX59_RS24465 (2016) | 2016..2339 | - | 324 | WP_238869670.1 | Transcriptional repressor MprA | VF |
| JFX59_RS25915 (2388) | 2388..2564 | - | 177 | Protein_4 | Transcriptional repressor MprA | VF |
| JFX59_RS24470 (2631) | 2631..4070 | - | 1440 | WP_001213534.1 | Hemolysin secretion protein D, chromosomal | VF |
| JFX59_RS24475 (4074) | 4074..6194 | - | 2121 | WP_072094473.1 | Alpha-hemolysin translocation ATP-binding protein HlyB | VF |
| JFX59_RS24480 (6244) | 6244..9240 | - | 2997 | WP_011310119.1 | Hemolysin, chromosomal | VF |
| JFX59_RS24485 (9242) | 9242..9757 | - | 516 | WP_001365635.1 | RTX-I toxin-activating lysine-acyltransferase ApxIC | VF |
| JFX59_RS24490 (10185) | 10185..10988 | - | 804 | WP_000899428.1 | Outer membrane protein A | VF |
| JFX59_RS24495 (11013) | 11013..15320 | - | 4308 | WP_215771216.1 | Autotransporter adhesin SadA | VF |
| JFX59_RS24500 (15535) | 15535..15819 | - | 285 | WP_000439678.1 | Major pilu subunit operon regulatory protein PapB | VF |
| JFX59_RS24505 (16427) | 16427..16974 | + | 548 | Protein_12 | transposase | - |
| JFX59_RS24510 (17304) | 17304..17738 | + | 435 | Protein_13 | IS110 family transposase ISEc21 | Transposase |
| JFX59_RS24515 (17825) | 17825..19362 | + | 1538 | Protein_14 | IS3 family transposase | - |
| JFX59_RS24520 (19467) | 19467..20096 | + | 630 | Protein_15 | transposase | - |
| JFX59_RS24525 (20116) | 20116..20464 | + | 349 | Protein_16 | integrase core domain-containing protein | - |
| JFX59_RS24530 (20829) | 20829..22385 | + | 1557 | WP_000554412.1 | L-lactate permease | - |
| JFX59_RS24535 (22436) | 22436..23155 | + | 720 | WP_001102093.1 | (Fe-S)-binding protein | - |
| JFX59_RS24540 (23166) | 23166..24581 | + | 1416 | WP_000054160.1 | LutB/LldF family L-lactate oxidation iron-sulfur protein | - |
| JFX59_RS24545 (24586) | 24586..25284 | + | 699 | WP_000431492.1 | lactate utilization protein C | - |
| JFX59_RS24550 (25325) | 25325..25561 | - | 237 | WP_001369996.1 | hypothetical protein | - |
| JFX59_RS24555 (25632) | 25632..26045 | - | 414 | Protein_22 | IS3 family transposase ISKpn8 | Transposase |
| JFX59_RS24560 (26548) | 26548..26739 | - | 192 | WP_000264906.1 | hypothetical protein | - |
| JFX59_RS24565 (26749) | 26749..27114 | - | 366 | Protein_24 | hypothetical protein | - |
| JFX59_RS24570 (27606) | 27606..31508 | - | 3903 | WP_215771217.1 | Serine protease EspP | VF |
| JFX59_RS24580 (33224) | 33224..33727 | - | 504 | Protein_27 | thermonuclease family protein | - |
| JFX59_RS24585 (33886) | 33886..34563 | + | 678 | WP_024213798.1 | hypothetical protein | - |
| JFX59_RS24590 (35053) | 35053..35373 | - | 321 | WP_000220092.1 | hypothetical protein | - |
| JFX59_RS24595 (35431) | 35431..36593 | - | 1163 | Protein_30 | IS3-like element IS3 family transposase | - |
| JFX59_RS24600 (36660) | 36660..36749 | - | 90 | Protein_31 | transposase | - |
| JFX59_RS24605 (37004) | 37004..38275 | + | 1272 | WP_044527432.1 | Adhesin YadA | VF |
| JFX59_RS24610 (38526) | 38526..39589 | + | 1064 | Protein_33 | IS3 family transposase | - |
| JFX59_RS24615 (39897) | 39897..41984 | + | 2088 | WP_001223214.1 | bifunctional siderophore receptor/adhesin Iha | - |
| JFX59_RS24620 (42245) | 42245..42667 | - | 423 | WP_096936667.1 | Exc2 family lipoprotein | - |
| JFX59_RS24625 (43002) | 43002..43169 | - | 168 | Protein_36 | IS110 family transposase | - |
| JFX59_RS24630 (43246) | 43246..43434 | + | 189 | Protein_37 | IS66 family transposase IS682 | Transposase |
| JFX59_RS25920 (43438) | 43438..43647 | - | 210 | Protein_38 | hypothetical protein | - |
| JFX59_RS24635 (43718) | 43718..44143 | - | 426 | WP_001373081.1 | subtilase AB5 cytotoxin subunit B | - |
| JFX59_RS24640 (44160) | 44160..45203 | - | 1044 | WP_000912970.1 | subtilase AB5 cytotoxin subunit A | - |
| JFX59_RS24645 (45257) | 45257..46221 | - | 965 | Protein_41 | transposase | - |
| JFX59_RS24650 (46252) | 46252..46600 | - | 349 | Protein_42 | IS66 family transposase IS682 | Transposase |
| JFX59_RS24655 (46597) | 46597..47022 | - | 426 | WP_000435654.1 | IS66 family transposase IS682 | Transposase |
| JFX59_RS24660 (47327) | 47327..47512 | - | 186 | WP_071531845.1 | CPCC family cysteine-rich protein | - |
| JFX59_RS24665 (47512) | 47512..48735 | - | 1224 | Protein_45 | VENN motif pre-toxin domain-containing protein | - |
| JFX59_RS24670 (49066) | 49066..49239 | + | 174 | Protein_46 | Tn3 family transposase | - |
| JFX59_RS24675 (49436) | 49436..50429 | + | 994 | Protein_47 | IS110 family transposase IS5075 | Transposase |
| JFX59_RS24680 (50858) | 50858..51118 | - | 261 | WP_000038919.1 | hypothetical protein | - |
| JFX59_RS24685 (51111) | 51111..60551 | - | 9441 | WP_060612756.1 | tRNA nuclease CdiA | VF |
| JFX59_RS24690 (60564) | 60564..62330 | - | 1767 | WP_047082308.1 | Hemolysin transporter protein ShlB | VF |
| JFX59_RS24695 (62945) | 62945..63184 | - | 240 | WP_000859017.1 | winged helix-turn-helix transcriptional regulator | - |
| JFX59_RS24705 (64160) | 64160..65017 | - | 858 | WP_000130991.1 | incFII family plasmid replication initiator RepA | - |
| JFX59_RS24710 (65010) | 65010..65084 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| JFX59_RS24715 (65319) | 65319..65576 | - | 258 | WP_000084404.1 | replication regulatory protein RepA | - |
| JFX59_RS24720 (65860) | 65860..66009 | - | 150 | WP_001336447.1 | Hok/Gef family protein | Toxin Detail |
| - (66057) | 66057..66113 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - (66057) | 66057..66113 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - (66057) | 66057..66113 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| - (66057) | 66057..66113 | + | 57 | NuclAT_1 | - | Antitoxin Detail |
| JFX59_RS26095 (66288) | 66288..66422 | - | 135 | WP_001058542.1 | hypothetical protein | - |
| JFX59_RS24730 (66773) | 66773..67234 | - | 462 | WP_000760084.1 | thermonuclease family protein | - |
| JFX59_RS24735 (67977) | 67977..68180 | - | 204 | WP_038811942.1 | hypothetical protein | - |
| JFX59_RS24740 (68330) | 68330..68887 | - | 558 | WP_024213676.1 | fertility inhibition protein FinO | - |
| JFX59_RS24745 (68923) | 68923..69291 | - | 369 | WP_000722534.1 | NirD/YgiW/YdeI family stress tolerance protein | - |
| JFX59_RS24750 (69374) | 69374..70120 | - | 747 | WP_024213675.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| JFX59_RS24755 (70140) | 70140..75410 | - | 5271 | WP_024213674.1 | Multifunctional conjugation protein TraI | Relaxase |
| JFX59_RS24760 (75410) | 75410..77617 | - | 2208 | WP_123129820.1 | type IV conjugative transfer system coupling protein TraD | - |
| JFX59_RS24765 (77899) | 77899..78510 | - | 612 | WP_244469997.1 | hypothetical protein | - |
| JFX59_RS24770 (78582) | 78582..79313 | - | 732 | WP_033800894.1 | conjugal transfer complement resistance protein TraT | - |
| JFX59_RS24775 (79345) | 79345..79848 | - | 504 | WP_077637628.1 | surface exclusion protein | - |
| JFX59_RS24780 (79864) | 79864..82686 | - | 2823 | WP_024213669.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| JFX59_RS24785 (82683) | 82683..84056 | - | 1374 | WP_024213668.1 | conjugal transfer pilus assembly protein TraH | - |
| JFX59_RS24790 (84043) | 84043..84435 | - | 393 | WP_024213667.1 | F-type conjugal transfer protein TrbF | - |
| JFX59_RS24795 (84416) | 84416..84763 | - | 348 | WP_071531747.1 | P-type conjugative transfer protein TrbJ | - |
| JFX59_RS24800 (84693) | 84693..85238 | - | 546 | WP_001477377.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| JFX59_RS24805 (85225) | 85225..85512 | - | 288 | WP_000335419.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| JFX59_RS24810 (85578) | 85578..85979 | - | 402 | WP_024213666.1 | hypothetical protein | - |
| JFX59_RS24815 (86110) | 86110..86475 | - | 366 | WP_024213665.1 | hypothetical protein | - |
| JFX59_RS24820 (86489) | 86489..87232 | - | 744 | WP_024213664.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| JFX59_RS24825 (87225) | 87225..87482 | - | 258 | WP_024213663.1 | conjugal transfer protein TrbE | - |
| JFX59_RS24830 (87496) | 87496..89400 | - | 1905 | WP_024213662.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| JFX59_RS24835 (89635) | 89635..90015 | - | 381 | WP_024213661.1 | hypothetical protein | - |
| JFX59_RS24840 (90012) | 90012..90650 | - | 639 | WP_024213660.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| JFX59_RS24845 (90934) | 90934..91212 | - | 279 | WP_021573907.1 | hypothetical protein | - |
| JFX59_RS24850 (91239) | 91239..92231 | - | 993 | WP_000817328.1 | conjugal transfer pilus assembly protein TraU | - |
| JFX59_RS24855 (92228) | 92228..92860 | - | 633 | WP_000877291.1 | type-F conjugative transfer system protein TraW | - |
| JFX59_RS24860 (92857) | 92857..93243 | - | 387 | WP_024213659.1 | type-F conjugative transfer system protein TrbI | - |
| JFX59_RS24865 (93240) | 93240..95870 | - | 2631 | WP_024213658.1 | type IV secretion system protein TraC | - |
| JFX59_RS24870 (95995) | 95995..96342 | - | 348 | WP_000836684.1 | hypothetical protein | - |
| JFX59_RS25925 (96370) | 96370..96588 | - | 219 | WP_062855972.1 | hypothetical protein | - |
| JFX59_RS24875 (96668) | 96668..97087 | - | 420 | WP_202831963.1 | hypothetical protein | - |
| JFX59_RS24880 (97152) | 97152..97547 | - | 396 | WP_000549593.1 | hypothetical protein | - |
| JFX59_RS24885 (97540) | 97540..97761 | - | 222 | WP_001278977.1 | conjugal transfer protein TraR | - |
| JFX59_RS24890 (97896) | 97896..98411 | - | 516 | WP_198779935.1 | type IV conjugative transfer system lipoprotein TraV | - |
| JFX59_RS24895 (98408) | 98408..98659 | - | 252 | WP_001038336.1 | conjugal transfer protein TrbG | - |
| JFX59_RS24900 (98652) | 98652..98972 | - | 321 | WP_024214338.1 | conjugal transfer protein TrbD | - |
| JFX59_RS24905 (98959) | 98959..99546 | - | 588 | WP_024213653.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| JFX59_RS24910 (99536) | 99536..100966 | - | 1431 | WP_000146622.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| JFX59_RS24915 (100966) | 100966..101694 | - | 729 | WP_001365587.1 | type-F conjugative transfer system secretin TraK | - |
| JFX59_RS24920 (101681) | 101681..102247 | - | 567 | WP_000399759.1 | type IV conjugative transfer system protein TraE | - |
| JFX59_RS24925 (102269) | 102269..102580 | - | 312 | WP_000012108.1 | type IV conjugative transfer system protein TraL | - |
| JFX59_RS24930 (102595) | 102595..102948 | - | 354 | WP_001098216.1 | type IV conjugative transfer system pilin TraA | - |
| JFX59_RS24935 (102983) | 102983..103210 | - | 228 | WP_000589554.1 | conjugal transfer relaxosome protein TraY | - |
| JFX59_RS24940 (103329) | 103329..103976 | - | 648 | WP_024213652.1 | transcriptional regulator TraJ family protein | - |
| JFX59_RS24945 (104170) | 104170..104553 | - | 384 | WP_001585112.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| JFX59_RS24950 (104886) | 104886..105476 | + | 591 | WP_279600944.1 | hypothetical protein | VF |
| JFX59_RS24955 (105772) | 105772..106593 | - | 822 | WP_024213651.1 | DUF932 domain-containing protein | - |
| JFX59_RS24960 (106712) | 106712..106999 | - | 288 | WP_000107542.1 | hypothetical protein | - |
| JFX59_RS24965 (107155) | 107155..107457 | - | 303 | WP_024213649.1 | hypothetical protein | - |
| JFX59_RS24970 (107760) | 107760..108057 | + | 298 | Protein_106 | hypothetical protein | - |
| JFX59_RS24975 (108358) | 108358..108480 | - | 123 | WP_223200913.1 | Hok/Gef family protein | Toxin Detail |
| JFX59_RS25930 (108425) | 108425..108577 | - | 153 | Protein_108 | DUF5431 family protein | - |
| - (108584) | 108584..108778 | - | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (108584) | 108584..108778 | - | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (108584) | 108584..108778 | - | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (108584) | 108584..108778 | - | 195 | NuclAT_0 | - | Antitoxin Detail |
| JFX59_RS24980 (108727) | 108727..109041 | - | 315 | Protein_109 | theronine dehydrogenase | - |
| JFX59_RS24985 (109038) | 109038..109757 | - | 720 | WP_001276237.1 | plasmid SOS inhibition protein A | - |
| JFX59_RS24990 (109754) | 109754..110188 | - | 435 | WP_024213646.1 | conjugation system SOS inhibitor PsiB | - |
| JFX59_RS24995 (110243) | 110243..112201 | - | 1959 | WP_024213645.1 | ParB/RepB/Spo0J family partition protein | - |
| JFX59_RS25000 (112267) | 112267..112500 | - | 234 | WP_021564200.1 | DUF905 family protein | - |
| JFX59_RS25005 (112558) | 112558..113091 | - | 534 | WP_024213643.1 | single-stranded DNA-binding protein | - |
| JFX59_RS25935 (113393) | 113393..113816 | + | 424 | Protein_115 | hypothetical protein | - |
| JFX59_RS25015 (113905) | 113905..114468 | - | 564 | WP_001385677.1 | class I SAM-dependent methyltransferase | - |
| JFX59_RS25020 (114514) | 114514..115875 | - | 1362 | WP_024213835.1 | DUF3560 domain-containing protein | - |
| JFX59_RS25025 (115927) | 115927..116157 | - | 231 | WP_000218649.1 | hypothetical protein | - |
| JFX59_RS25030 (116672) | 116672..117140 | + | 469 | Protein_119 | hypothetical protein | - |
| JFX59_RS25035 (117119) | 117119..117310 | - | 192 | WP_001027514.1 | hypothetical protein | - |
| JFX59_RS25040 (117310) | 117310..117729 | - | 420 | WP_000271736.1 | DUF1380 family protein | - |
| JFX59_RS25045 (117776) | 117776..118201 | - | 426 | WP_001198915.1 | antirestriction protein | - |
| JFX59_RS25050 (118617) | 118617..119387 | - | 771 | WP_024213723.1 | hypothetical protein | - |
| JFX59_RS25055 (119432) | 119432..119950 | - | 519 | WP_224065154.1 | DUF1380 family protein | - |
| JFX59_RS25060 (119880) | 119880..120101 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| JFX59_RS25065 (120102) | 120102..120785 | - | 684 | WP_024213724.1 | DNA methylase | - |
| JFX59_RS25070 (120862) | 120862..121167 | - | 306 | WP_038812301.1 | hypothetical protein | - |
| JFX59_RS25075 (121171) | 121171..122073 | - | 903 | WP_077629773.1 | DUF1281 domain-containing protein | - |
| JFX59_RS25080 (122492) | 122492..122740 | + | 249 | WP_000618108.1 | DinI-like family protein | - |
| JFX59_RS25085 (122737) | 122737..123174 | + | 438 | WP_000109074.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| JFX59_RS25090 (123174) | 123174..124444 | + | 1271 | Protein_131 | translesion error-prone DNA polymerase V subunit UmuC | - |
| JFX59_RS25095 (124449) | 124449..124841 | - | 393 | WP_000340836.1 | plasmid partitioning/stability family protein | - |
| JFX59_RS25100 (124846) | 124846..125817 | - | 972 | WP_001103695.1 | plasmid segregation protein ParM | - |
| JFX59_RS25105 (126046) | 126046..126690 | + | 645 | WP_000633912.1 | division plane positioning ATPase MipZ | - |
| JFX59_RS25110 (126684) | 126684..126959 | + | 276 | WP_000239527.1 | hypothetical protein | - |
| JFX59_RS25115 (127097) | 127097..127906 | - | 810 | WP_000016958.1 | site-specific integrase | - |
| JFX59_RS25120 (127907) | 127907..128212 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| JFX59_RS25125 (128214) | 128214..128432 | - | 219 | WP_198779936.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| JFX59_RS25130 (129028) | 129028..129288 | + | 261 | WP_000343084.1 | hypothetical protein | - |
| JFX59_RS25135 (129285) | 129285..129875 | + | 591 | WP_000194564.1 | hypothetical protein | - |
| JFX59_RS25140 (129893) | 129893..130240 | - | 348 | WP_000142428.1 | DUF6404 family protein | - |
| JFX59_RS25145 (130494) | 130494..130703 | + | 210 | WP_225303885.1 | colicin E1 immunity protein | - |
| JFX59_RS25150 (130710) | 130710..131030 | - | 321 | WP_001365556.1 | colicin-like pore-forming protein | - |
| JFX59_RS25155 (131140) | 131140..131871 | - | 732 | WP_000850413.1 | conjugal transfer complement resistance protein TraT | - |
| JFX59_RS25160 (132148) | 132148..132300 | - | 153 | Protein_145 | IS481 family transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|