MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 116496 bp
Accession: NZ_CP074703 Location: 1..116496 Organism: Escherichia coli strain 702/18 Replicon: plasmid p702_18_2
Accession: NZ_CP074703 Location: 1..116496 Organism: Escherichia coli strain 702/18 Replicon: plasmid p702_18_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KH969_RS25345 (KH969_25355) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| KH969_RS25350 (KH969_25360) | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| KH969_RS25355 (KH969_25365) | 2124..2306 | - | 183 | WP_042344623.1 | hypothetical protein | - |
| KH969_RS27370 | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KH969_RS25360 (KH969_25370) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| KH969_RS25365 (KH969_25375) | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| KH969_RS25370 (KH969_25380) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| KH969_RS25375 (KH969_25385) | 4904..5107 | - | 204 | Protein_7 | hypothetical protein | - |
| KH969_RS25380 (KH969_25390) | 5213..5488 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| KH969_RS25385 (KH969_25395) | 5488..5772 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| KH969_RS25390 (KH969_25400) | 6377..7129 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| KH969_RS25395 (KH969_25405) | 7175..8140 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| KH969_RS25400 (KH969_25410) | 8173..8553 | - | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| KH969_RS25405 (KH969_25415) | 8578..9468 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| KH969_RS25410 (KH969_25420) | 9869..10309 | + | 441 | Protein_14 | zinc-binding dehydrogenase | - |
| KH969_RS25415 (KH969_25425) | 10440..11318 | + | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| KH969_RS25420 (KH969_25430) | 11308..12195 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| KH969_RS25425 (KH969_25435) | 12206..13030 | + | 825 | WP_217477956.1 | phosphodiesterase | - |
| KH969_RS25430 (KH969_25440) | 13036..14109 | + | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| KH969_RS25435 (KH969_25445) | 14102..15412 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| KH969_RS25440 (KH969_25450) | 15471..15779 | - | 309 | Protein_20 | IS4 family transposase ISEc13 | Transposase |
| KH969_RS25445 (KH969_25455) | 15856..16029 | - | 174 | WP_000338295.1 | Tn3 family transposase ISPsy39 | Transposase |
| KH969_RS25450 (KH969_25460) | 16111..17307 | - | 1197 | Protein_22 | IS3 family transposase | - |
| KH969_RS25455 (KH969_25465) | 17332..18036 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KH969_RS25460 (KH969_25470) | 18094..18624 | - | 531 | Protein_24 | histidine-type phosphatase | - |
| KH969_RS25465 (KH969_25475) | 18746..19231 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| KH969_RS25470 (KH969_25480) | 19256..19741 | - | 486 | WP_001267177.1 | TlpA disulfide reductase family protein | - |
| KH969_RS25475 (KH969_25485) | 19728..20423 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| KH969_RS25480 (KH969_25490) | 20428..21558 | - | 1131 | WP_000729220.1 | ABC transporter permease | - |
| KH969_RS25485 (KH969_25495) | 21548..22831 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| KH969_RS25490 (KH969_25500) | 22834..24213 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| KH969_RS25495 (KH969_25505) | 24317..24844 | - | 528 | WP_000178050.1 | iron transporter | - |
| KH969_RS25500 (KH969_25510) | 24885..26771 | - | 1887 | WP_000118029.1 | FTR1 family protein | - |
| KH969_RS25505 (KH969_25515) | 27118..27879 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| KH969_RS25510 (KH969_25520) | 28116..28622 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| KH969_RS25515 (KH969_25525) | 28612..28782 | - | 171 | Protein_35 | DsbA family protein | - |
| KH969_RS25520 (KH969_25530) | 28920..29033 | - | 114 | Protein_36 | IS6 family transposase IS15DI | Transposase |
| KH969_RS25525 (KH969_25535) | 29233..29930 | + | 698 | WP_151884388.1 | IS1 family transposase IS1X2 | Transposase |
| KH969_RS25530 (KH969_25540) | 30190..30783 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| KH969_RS25535 (KH969_25545) | 30896..32101 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| KH969_RS25540 (KH969_25550) | 32183..32806 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| KH969_RS25545 (KH969_25555) | 32784..33470 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| KH969_RS25550 (KH969_25560) | 33478..33864 | - | 387 | WP_000460651.1 | hypothetical protein | - |
| KH969_RS25555 (KH969_25565) | 33857..34120 | - | 264 | WP_049802299.1 | antibiotic biosynthesis monooxygenase | - |
| KH969_RS25565 (KH969_25575) | 34904..35377 | - | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| KH969_RS25570 (KH969_25580) | 35535..36548 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| KH969_RS25575 (KH969_25585) | 36751..37101 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| KH969_RS25580 (KH969_25590) | 37227..37505 | + | 279 | Protein_48 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| KH969_RS25585 (KH969_25595) | 37555..38259 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KH969_RS25590 (KH969_25600) | 38325..38486 | + | 162 | Protein_50 | LysR family transcriptional regulator | - |
| KH969_RS25595 (KH969_25605) | 38604..40097 | + | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| KH969_RS27375 | 40128..41012 | + | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| KH969_RS25605 (KH969_25615) | 41229..42443 | + | 1215 | WP_023300759.1 | Bicyclomycin resistance protein | ARG |
| KH969_RS27380 | 42471..42632 | + | 162 | Protein_54 | LysR family transcriptional regulator | - |
| KH969_RS25610 (KH969_25620) | 42667..43371 | - | 705 | WP_001067856.1 | IS6 family transposase IS15DII | Transposase |
| KH969_RS25615 (KH969_25625) | 43497..43808 | - | 312 | WP_000198428.1 | IS3 family transposase ISKpn11 | Transposase |
| KH969_RS25620 (KH969_25630) | 43894..44154 | - | 261 | Protein_57 | hypothetical protein | - |
| KH969_RS25625 (KH969_25635) | 44167..45027 | - | 861 | WP_000557452.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| KH969_RS25630 (KH969_25640) | 45169..46029 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| KH969_RS25635 (KH969_25645) | 46212..46466 | - | 255 | Protein_60 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KH969_RS25640 (KH969_25650) | 46530..47234 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KH969_RS25645 (KH969_25655) | 47287..47514 | + | 228 | Protein_62 | helix-turn-helix domain-containing protein | - |
| KH969_RS25650 (KH969_25660) | 47697..48557 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| KH969_RS25655 (KH969_25665) | 48704..48985 | + | 282 | Protein_64 | transposase zinc-binding domain-containing protein | - |
| KH969_RS25660 (KH969_25670) | 49155..49859 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KH969_RS25665 (KH969_25675) | 49920..50756 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| KH969_RS25670 (KH969_25680) | 50756..51559 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| KH969_RS25675 (KH969_25685) | 51620..52435 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| KH969_RS25680 (KH969_25690) | 52743..53594 | - | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| KH969_RS25685 (KH969_25695) | 53581..54300 | - | 720 | Protein_70 | helicase RepA family protein | - |
| KH969_RS25690 (KH969_25700) | 54350..55054 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KH969_RS25695 (KH969_25705) | 55205..56020 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| KH969_RS25700 (KH969_25710) | 56210..56914 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KH969_RS25705 (KH969_25715) | 56979..58229 | - | 1251 | Protein_74 | transposase | - |
| KH969_RS27385 | 58304..58387 | - | 84 | Protein_75 | hypothetical protein | - |
| KH969_RS25710 (KH969_25720) | 58502..58660 | + | 159 | Protein_76 | chromate resistance protein | - |
| KH969_RS25715 (KH969_25725) | 59288..60659 | - | 1372 | Protein_77 | IS1182 family transposase ISCfr1 | Transposase |
| KH969_RS25720 (KH969_25730) | 60774..61910 | - | 1137 | WP_000080860.1 | DUF3883 domain-containing protein | - |
| KH969_RS25725 (KH969_25735) | 61961..62188 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| KH969_RS25730 (KH969_25740) | 62212..62403 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| KH969_RS25735 (KH969_25745) | 62884..63426 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| KH969_RS25740 (KH969_25750) | 63439..64299 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| KH969_RS25745 (KH969_25755) | 64442..65347 | + | 906 | Protein_83 | IS4 family transposase IS10R | Transposase |
| KH969_RS25750 (KH969_25760) | 65396..66100 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KH969_RS25755 (KH969_25765) | 66137..66871 | - | 735 | WP_023146395.1 | DUF262 domain-containing protein | - |
| KH969_RS25760 (KH969_25770) | 67156..67557 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KH969_RS25765 (KH969_25775) | 67490..67747 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KH969_RS25770 (KH969_25780) | 67840..68493 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| KH969_RS25775 (KH969_25785) | 69707..69919 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| KH969_RS25780 (KH969_25790) | 70050..70412 | - | 363 | Protein_90 | fertility inhibition protein FinO | - |
| KH969_RS25785 (KH969_25795) | 70408..73659 | - | 3252 | Protein_91 | Multifunctional conjugation protein TraI | Relaxase |
| KH969_RS25790 (KH969_25800) | 73659..75395 | - | 1737 | WP_169063395.1 | type IV conjugative transfer system coupling protein TraD | - |
| KH969_RS25795 (KH969_25805) | 75379..77043 | - | 1665 | Protein_93 | conjugal transfer mating pair stabilization protein TraG | - |
| KH969_RS25805 (KH969_25815) | 77123..77575 | - | 453 | Protein_94 | DNA methyltransferase | - |
| KH969_RS25810 (KH969_25820) | 77652..77963 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| KH969_RS25815 (KH969_25825) | 77960..78862 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| KH969_RS25820 (KH969_25830) | 79729..80700 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| KH969_RS25825 (KH969_25835) | 80700..81866 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| KH969_RS25830 (KH969_25840) | 82454..83209 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| KH969_RS25835 (KH969_25845) | 83983..84789 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| KH969_RS25840 (KH969_25850) | 84790..85095 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| KH969_RS25845 (KH969_25855) | 85097..85315 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| KH969_RS25850 (KH969_25860) | 85906..86394 | + | 489 | WP_011254646.1 | hypothetical protein | - |
| KH969_RS25855 (KH969_25865) | 86428..87561 | - | 1134 | WP_001542067.1 | DUF3800 domain-containing protein | - |
| KH969_RS25860 (KH969_25870) | 87728..88501 | - | 774 | WP_000905949.1 | hypothetical protein | - |
| KH969_RS25865 (KH969_25875) | 88514..89014 | - | 501 | WP_000528931.1 | HEPN family nuclease | - |
| KH969_RS25870 (KH969_25880) | 89279..89509 | + | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KH969_RS25875 (KH969_25885) | 89506..89922 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KH969_RS25880 (KH969_25890) | 89967..93761 | - | 3795 | WP_001144732.1 | hypothetical protein | - |
| KH969_RS25885 (KH969_25895) | 94142..94372 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KH969_RS25890 (KH969_25900) | 94369..94785 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KH969_RS25895 (KH969_25905) | 94860..96425 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| KH969_RS25900 (KH969_25910) | 96410..97432 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| KH969_RS25910 (KH969_25920) | 98739..99653 | + | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| KH969_RS25915 (KH969_25925) | 99653..100480 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| KH969_RS25920 (KH969_25930) | 100477..101334 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| KH969_RS25925 (KH969_25935) | 101331..102188 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| KH969_RS25930 (KH969_25940) | 102422..102679 | - | 258 | Protein_119 | transposase | - |
| KH969_RS25935 (KH969_25945) | 102677..103090 | + | 414 | Protein_120 | phosphopyruvate hydratase | - |
| KH969_RS25940 (KH969_25950) | 103431..103811 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| KH969_RS25945 (KH969_25955) | 104191..105384 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| KH969_RS25950 (KH969_25960) | 105520..107244 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| KH969_RS25955 (KH969_25965) | 107245..108192 | + | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| KH969_RS25960 (KH969_25970) | 108192..109934 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| KH969_RS25965 (KH969_25975) | 109931..111264 | + | 1334 | Protein_126 | L-lysine N6-monooxygenase | VF |
| KH969_RS25970 (KH969_25980) | 111290..113491 | + | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| KH969_RS25975 (KH969_25985) | 113871..114568 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| KH969_RS25980 (KH969_25990) | 114748..115261 | - | 514 | Protein_129 | DUF4113 domain-containing protein | - |
| KH969_RS25985 (KH969_25995) | 115322..115426 | - | 105 | Protein_130 | AAA family ATPase | - |
| KH969_RS25990 (KH969_26000) | 115428..115751 | - | 324 | Protein_131 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|