MGE detailed information

MGE type: Conjugative plasmid        MGE length: 99826 bp
Accession: NZ_CP074124        Location: 1..99826         Organism: Escherichia coli strain EC16       Replicon: plasmid pEC16-CTX-55


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KGQ53_RS25020 () 1..858 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
KGQ53_RS25025 () 1797..1955 + 159 WP_047667301.1 membrane protein -
KGQ53_RS25030 () 2119..3318 - 1200 WP_000948429.1 IS91 family transposase ISSbo1 Transposase
KGQ53_RS25035 () 3328..3516 - 189 WP_000957857.1 hypothetical protein -
KGQ53_RS25040 () 3746..3850 + 105 WP_032409716.1 hypothetical protein -
KGQ53_RS25045 () 3979..4236 + 258 WP_000764642.1 hypothetical protein -
KGQ53_RS25050 () 4294..5070 - 777 WP_000015958.1 site-specific integrase -
KGQ53_RS25055 () 5067..5810 - 744 WP_000129823.1 hypothetical protein -
KGQ53_RS25060 () 5861..6211 - 351 WP_000493378.1 hypothetical protein -
KGQ53_RS25065 () 6763..7851 + 1089 WP_000952217.1 transcriptional repressor PifC -
KGQ53_RS25070 () 7853..10078 + 2226 WP_000698737.1 P-loop NTPase fold protein -
KGQ53_RS25075 () 10216..10596 + 381 WP_029364370.1 transposase -
KGQ53_RS25080 () 10593..10940 + 348 WP_000612591.1 IS66 family transposase ISEc8 Transposase
KGQ53_RS25085 () 10990..12528 + 1539 WP_072643824.1 IS66 family transposase ISEc8 Transposase
KGQ53_RS25090 () 12578..13477 - 900 WP_000963206.1 nucleotide-binding protein -
KGQ53_RS25095 () 13467..13757 - 291 WP_000111771.1 hypothetical protein -
KGQ53_RS25100 () 14053..14283 + 231 WP_001261287.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
KGQ53_RS25105 () 14280..14696 + 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
KGQ53_RS25110 () 14858..16996 - 2139 WP_000350638.1 AAA family ATPase -
KGQ53_RS25115 () 17350..17607 + 258 WP_000343085.1 hypothetical protein -
KGQ53_RS25120 () 17607..18197 + 591 WP_000194575.1 hypothetical protein -
KGQ53_RS25125 () 18460..20016 + 1557 WP_000818556.1 AAA family ATPase -
KGQ53_RS25130 () 20208..20825 + 618 WP_000521603.1 ProQ/FINO family protein -
KGQ53_RS25135 () 21118..22155 - 1038 WP_044502555.1 permease -
KGQ53_RS25140 () 22260..22583 + 324 WP_001175594.1 metalloregulator ArsR/SmtB family transcription factor -
KGQ53_RS25145 () 22782..23486 + 705 WP_102204227.1 IS6 family transposase IS15DI Transposase
KGQ53_RS25150 () 23492..24220 + 729 WP_152921961.1 replication initiation protein -
KGQ53_RS25160 () 26369..26914 + 546 WP_001493763.1 plasmid pRiA4b ORF-3 family protein -
KGQ53_RS25165 () 27051..27623 + 573 WP_001493762.1 Tn3 family transposase TnpR_ISPa40 Transposase
KGQ53_RS25170 () 27660..29051 + 1392 WP_001493761.1 ISKra4 family transposase ISKpn19 Transposase
KGQ53_RS25175 () 29331..29987 - 657 WP_001516695.1 Pentapeptide repeat protein ARG
KGQ53_RS25180 () 30382..31397 + 1016 Protein_31 IS3 family transposase ISEc36 Transposase
KGQ53_RS25185 () 31440..32738 - 1299 Protein_32 Tn3 family transposase TnpA_Tn3 Transposase
KGQ53_RS25190 () 32806..33509 + 704 Protein_33 IS6 family transposase IS26 Transposase
KGQ53_RS25195 () 33703..34089 + 387 WP_063102497.1 bleomycin binding protein -
KGQ53_RS25200 () 34410..34802 - 393 WP_104690414.1 pyridoxamine 5'-phosphate oxidase family protein -
KGQ53_RS25205 () 35137..35841 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
KGQ53_RS25210 () 35896..36096 + 201 Protein_37 DDE-type integrase/transposase/recombinase -
KGQ53_RS25215 () 36151..36576 + 426 Protein_38 TetR/AcrR family transcriptional regulator -
KGQ53_RS25220 () 36596..37384 + 789 WP_014839978.1 winged helix-turn-helix domain-containing protein -
KGQ53_RS25225 () 37384..37902 + 519 WP_014839979.1 FidL-like protein -
KGQ53_RS25230 () 37907..38323 - 417 WP_014839980.1 Glutathione transferase FosA ARG
KGQ53_RS25235 () 38709..39413 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
KGQ53_RS25240 () 39463..40206 + 744 Protein_43 Beta-lactamase TEM ARG
KGQ53_RS25245 () 40465..40941 + 477 WP_013023839.1 WbuC family cupin fold metalloprotein -
KGQ53_RS25250 () 40988..41863 - 876 WP_015387340.1 Beta-lactamase CTX-M-1 ARG
KGQ53_RS25255 () 42285..42989 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
KGQ53_RS25260 () 43055..43120 + 66 Protein_47 IS1 family transposase -
KGQ53_RS25265 () 44569..44803 + 235 Protein_48 type II toxin-antitoxin system RelE/ParE family toxin -
KGQ53_RS25270 () 44931..45134 + 204 Protein_49 hypothetical protein -
KGQ53_RS25275 () 45335..45685 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
KGQ53_RS25280 () 45688..46650 - 963 WP_000959884.1 plasmid segregation protein ParM -
KGQ53_RS25285 () 46797..47090 + 294 WP_032146011.1 hypothetical protein -
KGQ53_RS25290 () 47167..47850 + 684 WP_000085883.1 DNA methylase -
KGQ53_RS25295 () 47851..48072 + 222 WP_001104881.1 hypothetical protein -
KGQ53_RS25300 () 48086..48520 + 435 WP_000274503.1 DUF1380 family protein -
KGQ53_RS25305 () 48571..49347 + 777 WP_212639664.1 hypothetical protein -
KGQ53_RS25310 () 49765..50190 + 426 WP_001198928.1 antirestriction protein -
KGQ53_RS25315 () 50237..50659 + 423 WP_000271762.1 DUF1380 family protein -
KGQ53_RS25320 () 50656..50847 + 192 WP_001027493.1 hypothetical protein -
KGQ53_RS25325 () 51885..52115 + 231 WP_000218642.1 hypothetical protein -
KGQ53_RS25330 () 52167..53528 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
KGQ53_RS25335 () 53575..54138 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
KGQ53_RS26025 () 54224..54673 - 450 Protein_63 hypothetical protein -
KGQ53_RS25340 () 54975..55502 + 528 WP_000290834.1 single-stranded DNA-binding protein -
KGQ53_RS25345 () 55560..55793 + 234 WP_000006003.1 DUF905 family protein -
KGQ53_RS25350 () 55854..57856 + 2003 Protein_66 ParB/RepB/Spo0J family partition protein -
KGQ53_RS25355 () 57925..58359 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
KGQ53_RS25360 () 58356..59118 + 763 Protein_68 plasmid SOS inhibition protein A -
- () 59087..59311 + 225 NuclAT_0 - -
- () 59087..59311 + 225 NuclAT_0 - -
- () 59087..59311 + 225 NuclAT_0 - -
- () 59087..59311 + 225 NuclAT_0 - -
KGQ53_RS25365 () 59096..59275 - 180 WP_001309233.1 hypothetical protein -
- 59244..59309 - 66 - - -
KGQ53_RS26030 () 59297..59446 + 150 Protein_70 plasmid maintenance protein Mok -
KGQ53_RS25370 () 59388..59513 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
KGQ53_RS25375 () 59832..60128 - 297 Protein_72 hypothetical protein -
KGQ53_RS25380 () 60428..60724 + 297 WP_001272251.1 hypothetical protein -
KGQ53_RS25385 () 60835..61656 + 822 WP_212639660.1 DUF932 domain-containing protein -
KGQ53_RS25390 () 61953..62600 - 648 WP_015059008.1 hypothetical protein VF
KGQ53_RS25395 () 62877..63260 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
KGQ53_RS25400 () 63451..64137 + 687 WP_212639661.1 PAS domain-containing protein -
KGQ53_RS25405 () 64230..64457 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
KGQ53_RS25410 () 64491..64856 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
KGQ53_RS25415 () 64871..65182 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
KGQ53_RS25420 () 65204..65770 + 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
KGQ53_RS25425 () 65757..66485 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
KGQ53_RS25430 () 66485..67912 + 1428 WP_000146635.1 F-type conjugal transfer pilus assembly protein TraB -
KGQ53_RS25435 () 67902..68492 + 591 WP_001376242.1 conjugal transfer pilus-stabilizing protein TraP -
KGQ53_RS25440 () 68479..68676 + 198 WP_001324648.1 conjugal transfer protein TrbD -
KGQ53_RS25445 () 68688..68939 + 252 WP_001038342.1 conjugal transfer protein TrbG -
KGQ53_RS25450 () 68936..69451 + 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
KGQ53_RS25455 () 69586..69807 + 222 WP_001278689.1 conjugal transfer protein TraR -
KGQ53_RS25460 () 69967..72594 + 2628 WP_015059012.1 type IV secretion system protein TraC -
KGQ53_RS25465 () 72591..72977 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
KGQ53_RS25470 () 72974..73606 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
KGQ53_RS25475 () 73603..74595 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
KGQ53_RS25480 () 74622..74930 + 309 WP_000412447.1 hypothetical protein -
KGQ53_RS25485 () 74993..75514 + 522 WP_015059014.1 hypothetical protein -
KGQ53_RS25490 () 75541..76179 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
KGQ53_RS25495 () 76176..76547 + 372 WP_000056336.1 hypothetical protein -
KGQ53_RS25500 () 76573..76995 + 423 Protein_97 HNH endonuclease -
KGQ53_RS25505 () 76992..78842 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
KGQ53_RS25510 () 78869..79126 + 258 WP_053913405.1 conjugal transfer protein TrbE -
KGQ53_RS25515 () 79119..79862 + 744 WP_015059017.1 type-F conjugative transfer system pilin assembly protein TraF -
KGQ53_RS25520 () 80023..80259 + 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
KGQ53_RS25525 () 80246..80791 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
KGQ53_RS25530 () 80781..81095 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
KGQ53_RS25535 () 81049..81441 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
KGQ53_RS25540 () 81428..82801 + 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
KGQ53_RS25545 () 82798..85614 + 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
KGQ53_RS25550 () 85647..86168 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
KGQ53_RS25555 () 86193..86924 + 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
KGQ53_RS25560 () 87127..87864 + 738 WP_212639662.1 hypothetical protein -
KGQ53_RS25565 () 87915..90167 + 2253 WP_061093448.1 type IV conjugative transfer system coupling protein TraD -
KGQ53_RS25570 () 90167..95437 + 5271 WP_061093447.1 Multifunctional conjugation protein TraI Relaxase
KGQ53_RS25575 () 95457..96203 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
KGQ53_RS25580 () 96258..96818 + 561 WP_000139328.1 fertility inhibition protein FinO -
KGQ53_RS25585 () 96950..97150 + 201 WP_015059022.1 hypothetical protein -
KGQ53_RS25590 () 97536..98135 + 600 WP_032083981.1 PIN domain-containing protein -
KGQ53_RS25595 () 98197..98529 + 333 WP_152916585.1 hypothetical protein -
- () 98730..98789 - 60 NuclAT_1 - -
- () 98730..98789 - 60 NuclAT_1 - -
- () 98730..98789 - 60 NuclAT_1 - -
- () 98730..98789 - 60 NuclAT_1 - -
KGQ53_RS25600 () 98834..98983 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
KGQ53_RS25605 () 99267..99515 + 249 WP_000083837.1 replication regulatory protein RepA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance