MGE detailed information
MGE type: Conjugative plasmid MGE length: 99826 bp
Accession: NZ_CP074124 Location: 1..99826 Organism: Escherichia coli strain EC16 Replicon: plasmid pEC16-CTX-55
Accession: NZ_CP074124 Location: 1..99826 Organism: Escherichia coli strain EC16 Replicon: plasmid pEC16-CTX-55
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KGQ53_RS25020 (1) | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| KGQ53_RS25025 (1797) | 1797..1955 | + | 159 | WP_047667301.1 | membrane protein | - |
| KGQ53_RS25030 (2119) | 2119..3318 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| KGQ53_RS25035 (3328) | 3328..3516 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| KGQ53_RS25040 (3746) | 3746..3850 | + | 105 | WP_032409716.1 | hypothetical protein | - |
| KGQ53_RS25045 (3979) | 3979..4236 | + | 258 | WP_000764642.1 | hypothetical protein | - |
| KGQ53_RS25050 (4294) | 4294..5070 | - | 777 | WP_000015958.1 | site-specific integrase | - |
| KGQ53_RS25055 (5067) | 5067..5810 | - | 744 | WP_000129823.1 | hypothetical protein | - |
| KGQ53_RS25060 (5861) | 5861..6211 | - | 351 | WP_000493378.1 | hypothetical protein | - |
| KGQ53_RS25065 (6763) | 6763..7851 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| KGQ53_RS25070 (7853) | 7853..10078 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| KGQ53_RS25075 (10216) | 10216..10596 | + | 381 | WP_029364370.1 | transposase | - |
| KGQ53_RS25080 (10593) | 10593..10940 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| KGQ53_RS25085 (10990) | 10990..12528 | + | 1539 | WP_072643824.1 | IS66 family transposase ISEc8 | Transposase |
| KGQ53_RS25090 (12578) | 12578..13477 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| KGQ53_RS25095 (13467) | 13467..13757 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| KGQ53_RS25100 (14053) | 14053..14283 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KGQ53_RS25105 (14280) | 14280..14696 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KGQ53_RS25110 (14858) | 14858..16996 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| KGQ53_RS25115 (17350) | 17350..17607 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| KGQ53_RS25120 (17607) | 17607..18197 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| KGQ53_RS25125 (18460) | 18460..20016 | + | 1557 | WP_000818556.1 | AAA family ATPase | - |
| KGQ53_RS25130 (20208) | 20208..20825 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| KGQ53_RS25135 (21118) | 21118..22155 | - | 1038 | WP_044502555.1 | permease | - |
| KGQ53_RS25140 (22260) | 22260..22583 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KGQ53_RS25145 (22782) | 22782..23486 | + | 705 | WP_102204227.1 | IS6 family transposase IS15DI | Transposase |
| KGQ53_RS25150 (23492) | 23492..24220 | + | 729 | WP_152921961.1 | replication initiation protein | - |
| KGQ53_RS25160 (26369) | 26369..26914 | + | 546 | WP_001493763.1 | plasmid pRiA4b ORF-3 family protein | - |
| KGQ53_RS25165 (27051) | 27051..27623 | + | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| KGQ53_RS25170 (27660) | 27660..29051 | + | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| KGQ53_RS25175 (29331) | 29331..29987 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| KGQ53_RS25180 (30382) | 30382..31397 | + | 1016 | Protein_31 | IS3 family transposase ISEc36 | Transposase |
| KGQ53_RS25185 (31440) | 31440..32738 | - | 1299 | Protein_32 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KGQ53_RS25190 (32806) | 32806..33509 | + | 704 | Protein_33 | IS6 family transposase IS26 | Transposase |
| KGQ53_RS25195 (33703) | 33703..34089 | + | 387 | WP_063102497.1 | bleomycin binding protein | - |
| KGQ53_RS25200 (34410) | 34410..34802 | - | 393 | WP_104690414.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| KGQ53_RS25205 (35137) | 35137..35841 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| KGQ53_RS25210 (35896) | 35896..36096 | + | 201 | Protein_37 | DDE-type integrase/transposase/recombinase | - |
| KGQ53_RS25215 (36151) | 36151..36576 | + | 426 | Protein_38 | TetR/AcrR family transcriptional regulator | - |
| KGQ53_RS25220 (36596) | 36596..37384 | + | 789 | WP_014839978.1 | winged helix-turn-helix domain-containing protein | - |
| KGQ53_RS25225 (37384) | 37384..37902 | + | 519 | WP_014839979.1 | FidL-like protein | - |
| KGQ53_RS25230 (37907) | 37907..38323 | - | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| KGQ53_RS25235 (38709) | 38709..39413 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KGQ53_RS25240 (39463) | 39463..40206 | + | 744 | Protein_43 | Beta-lactamase TEM | ARG |
| KGQ53_RS25245 (40465) | 40465..40941 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| KGQ53_RS25250 (40988) | 40988..41863 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| KGQ53_RS25255 (42285) | 42285..42989 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| KGQ53_RS25260 (43055) | 43055..43120 | + | 66 | Protein_47 | IS1 family transposase | - |
| KGQ53_RS25265 (44569) | 44569..44803 | + | 235 | Protein_48 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KGQ53_RS25270 (44931) | 44931..45134 | + | 204 | Protein_49 | hypothetical protein | - |
| KGQ53_RS25275 (45335) | 45335..45685 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| KGQ53_RS25280 (45688) | 45688..46650 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| KGQ53_RS25285 (46797) | 46797..47090 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| KGQ53_RS25290 (47167) | 47167..47850 | + | 684 | WP_000085883.1 | DNA methylase | - |
| KGQ53_RS25295 (47851) | 47851..48072 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| KGQ53_RS25300 (48086) | 48086..48520 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| KGQ53_RS25305 (48571) | 48571..49347 | + | 777 | WP_212639664.1 | hypothetical protein | - |
| KGQ53_RS25310 (49765) | 49765..50190 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| KGQ53_RS25315 (50237) | 50237..50659 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| KGQ53_RS25320 (50656) | 50656..50847 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| KGQ53_RS25325 (51885) | 51885..52115 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| KGQ53_RS25330 (52167) | 52167..53528 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| KGQ53_RS25335 (53575) | 53575..54138 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| KGQ53_RS26025 (54224) | 54224..54673 | - | 450 | Protein_63 | hypothetical protein | - |
| KGQ53_RS25340 (54975) | 54975..55502 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| KGQ53_RS25345 (55560) | 55560..55793 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| KGQ53_RS25350 (55854) | 55854..57856 | + | 2003 | Protein_66 | ParB/RepB/Spo0J family partition protein | - |
| KGQ53_RS25355 (57925) | 57925..58359 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| KGQ53_RS25360 (58356) | 58356..59118 | + | 763 | Protein_68 | plasmid SOS inhibition protein A | - |
| KGQ53_RS25365 (59096) | 59096..59275 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - (59087) | 59087..59311 | + | 225 | NuclAT_0 | - | - |
| - (59087) | 59087..59311 | + | 225 | NuclAT_0 | - | - |
| - (59087) | 59087..59311 | + | 225 | NuclAT_0 | - | - |
| - (59087) | 59087..59311 | + | 225 | NuclAT_0 | - | - |
| KGQ53_RS26030 (59297) | 59297..59446 | + | 150 | Protein_70 | plasmid maintenance protein Mok | - |
| KGQ53_RS25370 (59388) | 59388..59513 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KGQ53_RS25375 (59832) | 59832..60128 | - | 297 | Protein_72 | hypothetical protein | - |
| KGQ53_RS25380 (60428) | 60428..60724 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| KGQ53_RS25385 (60835) | 60835..61656 | + | 822 | WP_212639660.1 | DUF932 domain-containing protein | - |
| KGQ53_RS25390 (61953) | 61953..62600 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| KGQ53_RS25395 (62877) | 62877..63260 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KGQ53_RS25400 (63451) | 63451..64137 | + | 687 | WP_212639661.1 | PAS domain-containing protein | - |
| KGQ53_RS25405 (64230) | 64230..64457 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| KGQ53_RS25410 (64491) | 64491..64856 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| KGQ53_RS25415 (64871) | 64871..65182 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KGQ53_RS25420 (65204) | 65204..65770 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| KGQ53_RS25425 (65757) | 65757..66485 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| KGQ53_RS25430 (66485) | 66485..67912 | + | 1428 | WP_000146635.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KGQ53_RS25435 (67902) | 67902..68492 | + | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KGQ53_RS25440 (68479) | 68479..68676 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| KGQ53_RS25445 (68688) | 68688..68939 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| KGQ53_RS25450 (68936) | 68936..69451 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KGQ53_RS25455 (69586) | 69586..69807 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| KGQ53_RS25460 (69967) | 69967..72594 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| KGQ53_RS25465 (72591) | 72591..72977 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| KGQ53_RS25470 (72974) | 72974..73606 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| KGQ53_RS25475 (73603) | 73603..74595 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| KGQ53_RS25480 (74622) | 74622..74930 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| KGQ53_RS25485 (74993) | 74993..75514 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| KGQ53_RS25490 (75541) | 75541..76179 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KGQ53_RS25495 (76176) | 76176..76547 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| KGQ53_RS25500 (76573) | 76573..76995 | + | 423 | Protein_97 | HNH endonuclease | - |
| KGQ53_RS25505 (76992) | 76992..78842 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KGQ53_RS25510 (78869) | 78869..79126 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| KGQ53_RS25515 (79119) | 79119..79862 | + | 744 | WP_015059017.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KGQ53_RS25520 (80023) | 80023..80259 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KGQ53_RS25525 (80246) | 80246..80791 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KGQ53_RS25530 (80781) | 80781..81095 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| KGQ53_RS25535 (81049) | 81049..81441 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| KGQ53_RS25540 (81428) | 81428..82801 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| KGQ53_RS25545 (82798) | 82798..85614 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KGQ53_RS25550 (85647) | 85647..86168 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| KGQ53_RS25555 (86193) | 86193..86924 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| KGQ53_RS25560 (87127) | 87127..87864 | + | 738 | WP_212639662.1 | hypothetical protein | - |
| KGQ53_RS25565 (87915) | 87915..90167 | + | 2253 | WP_061093448.1 | type IV conjugative transfer system coupling protein TraD | - |
| KGQ53_RS25570 (90167) | 90167..95437 | + | 5271 | WP_061093447.1 | Multifunctional conjugation protein TraI | Relaxase |
| KGQ53_RS25575 (95457) | 95457..96203 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| KGQ53_RS25580 (96258) | 96258..96818 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| KGQ53_RS25585 (96950) | 96950..97150 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| KGQ53_RS25590 (97536) | 97536..98135 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| KGQ53_RS25595 (98197) | 98197..98529 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (98730) | 98730..98789 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (98730) | 98730..98789 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (98730) | 98730..98789 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (98730) | 98730..98789 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| KGQ53_RS25600 (98834) | 98834..98983 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| KGQ53_RS25605 (99267) | 99267..99515 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|