MGE detailed information
MGE type: Conjugative plasmid MGE length: 134098 bp
Accession: NZ_CP073362 Location: 1..134098 Organism: Escherichia coli strain EC11 Replicon: plasmid plas2
Accession: NZ_CP073362 Location: 1..134098 Organism: Escherichia coli strain EC11 Replicon: plasmid plas2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KDN44_RS24405 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| KDN44_RS24410 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| KDN44_RS24415 (2124) | 2124..2312 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| KDN44_RS24420 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| KDN44_RS24425 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| KDN44_RS24430 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| KDN44_RS24435 (7449) | 7449..7628 | - | 180 | Protein_6 | integrase core domain-containing protein | - |
| KDN44_RS24440 (7767) | 7767..8966 | + | 1200 | Protein_7 | IS3 family transposase IS629 | Transposase |
| KDN44_RS24445 (9114) | 9114..9439 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| KDN44_RS25775 (9485) | 9485..9825 | + | 341 | Protein_9 | IS3 family transposase | - |
| KDN44_RS24450 (10420) | 10420..11607 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| KDN44_RS24455 (11604) | 11604..13544 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| KDN44_RS24460 (13548) | 13548..14918 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| KDN44_RS24465 (15392) | 15392..15586 | + | 195 | Protein_13 | IS200-IS605 family transposase IS200C | Transposase |
| KDN44_RS24470 (15715) | 15715..16656 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| KDN44_RS24475 (16891) | 16891..18280 | - | 1390 | Protein_15 | ISNCY family transposase ISKpn21 | Transposase |
| KDN44_RS24480 (18590) | 18590..18739 | - | 150 | Protein_16 | IS3 family transposase IS2 | Transposase |
| KDN44_RS24485 (18917) | 18917..20110 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| KDN44_RS24490 (21352) | 21352..22089 | - | 738 | Protein_18 | IS3 family transposase IS2 | Transposase |
| KDN44_RS24495 (22142) | 22142..23304 | + | 1163 | WP_085947598.1 | IS3 family transposase ISEc17 | Transposase |
| KDN44_RS24500 (23321) | 23321..23841 | - | 521 | Protein_20 | IS3 family transposase IS2 | Transposase |
| KDN44_RS24505 (24466) | 24466..24759 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| KDN44_RS24510 (24817) | 24817..25016 | - | 200 | Protein_22 | lysis protein | - |
| KDN44_RS24515 (25570) | 25570..26594 | + | 1025 | Protein_23 | integrase core domain-containing protein | - |
| KDN44_RS24520 (27905) | 27905..29020 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| KDN44_RS24525 (29160) | 29160..32819 | + | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| KDN44_RS24530 (32923) | 32923..34152 | + | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| KDN44_RS24535 (34237) | 34237..35193 | + | 957 | WP_000271274.1 | Ferri-bacillibactin esterase BesA | VF |
| KDN44_RS24540 (35238) | 35238..37415 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| KDN44_RS24545 (38281) | 38281..39315 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| KDN44_RS25780 (39496) | 39496..39797 | + | 302 | Protein_30 | hypothetical protein | - |
| KDN44_RS24550 (39875) | 39875..40183 | - | 309 | WP_000377483.1 | DUF6404 family protein | - |
| KDN44_RS24555 (40336) | 40336..40461 | - | 126 | Protein_32 | type II toxin-antitoxin system toxin YacB | - |
| KDN44_RS24560 (40461) | 40461..40729 | - | 269 | Protein_33 | type II toxin-antitoxin system antitoxin YacA | - |
| KDN44_RS24565 (41340) | 41340..42614 | + | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| KDN44_RS24570 (42607) | 42607..44703 | + | 2097 | WP_000184924.1 | microcin H47 export transporter peptidase/ATP-binding subunit MchF | - |
| KDN44_RS24575 (44873) | 44873..45184 | - | 312 | WP_001259758.1 | colicin V | - |
| KDN44_RS24580 (45162) | 45162..45398 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| KDN44_RS25785 (45517) | 45517..45960 | + | 444 | WP_001323891.1 | dehydrogenase | - |
| KDN44_RS25790 (45932) | 45932..46336 | + | 405 | WP_001389361.1 | hypothetical protein | - |
| KDN44_RS24590 (46338) | 46338..46607 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| KDN44_RS24595 (46604) | 46604..47506 | + | 903 | WP_072017750.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| KDN44_RS24600 (47660) | 47660..48040 | + | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| KDN44_RS24605 (48037) | 48037..48384 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| KDN44_RS24610 (48434) | 48434..49294 | + | 861 | Protein_44 | IS66 family transposase ISEc8 | Transposase |
| KDN44_RS24615 (49330) | 49330..50181 | - | 852 | Protein_45 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KDN44_RS24620 (50235) | 50235..50939 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KDN44_RS24625 (51090) | 51090..51905 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| KDN44_RS24630 (52095) | 52095..52799 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KDN44_RS24635 (52864) | 52864..54114 | - | 1251 | Protein_49 | transposase | - |
| KDN44_RS24640 (54189) | 54189..54857 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| KDN44_RS24645 (54893) | 54893..55129 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| KDN44_RS24650 (55126) | 55126..55488 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| KDN44_RS24655 (55506) | 55506..57200 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| KDN44_RS24660 (57252) | 57252..57674 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| KDN44_RS24665 (57710) | 57710..57985 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| KDN44_RS24670 (57999) | 57999..58349 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| KDN44_RS24675 (58421) | 58421..58855 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| KDN44_RS24685 (59908) | 59908..60309 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KDN44_RS24690 (60242) | 60242..60499 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KDN44_RS24695 (60592) | 60592..61245 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| KDN44_RS24700 (62184) | 62184..63041 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| KDN44_RS24705 (63034) | 63034..63516 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| KDN44_RS25795 (63509) | 63509..63556 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| KDN44_RS25800 (63547) | 63547..63798 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| KDN44_RS24715 (63815) | 63815..64072 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| KDN44_RS24720 (64356) | 64356..64505 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (64549) | 64549..64610 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64549) | 64549..64610 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64549) | 64549..64610 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (64549) | 64549..64610 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| KDN44_RS24725 (64866) | 64866..64940 | - | 75 | Protein_68 | endonuclease | - |
| KDN44_RS24730 (65186) | 65186..65398 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| KDN44_RS24735 (65534) | 65534..66094 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| KDN44_RS24740 (66197) | 66197..67057 | - | 861 | WP_000704514.1 | putative protein YcjY | VF |
| KDN44_RS24745 (67116) | 67116..67862 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| KDN44_RS24750 (67882) | 67882..68571 | - | 690 | Protein_73 | Multifunctional conjugation protein TraI | Relaxase |
| KDN44_RS24755 (68635) | 68635..69339 | + | 705 | WP_001067855.1 | Multifunctional conjugation protein TraI | Relaxase |
| KDN44_RS24760 (69391) | 69391..69681 | - | 291 | Protein_75 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| KDN44_RS24765 (69807) | 69807..70157 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| KDN44_RS24770 (70360) | 70360..71373 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| KDN44_RS24775 (71531) | 71531..72004 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| KDN44_RS24780 (72135) | 72135..72923 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| KDN44_RS24785 (73004) | 73004..73708 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KDN44_RS25805 (74250) | 74250..74419 | + | 170 | Protein_81 | hypothetical protein | - |
| KDN44_RS25810 (74602) | 74602..74682 | - | 81 | Protein_82 | hypothetical protein | - |
| KDN44_RS24790 (74752) | 74752..74958 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| KDN44_RS24795 (74984) | 74984..75523 | + | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| KDN44_RS24800 (75591) | 75591..75824 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| KDN44_RS24805 (75852) | 75852..76049 | + | 198 | Protein_86 | hypothetical protein | - |
| KDN44_RS24810 (76104) | 76104..76538 | + | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| KDN44_RS24815 (76535) | 76535..77297 | + | 763 | Protein_88 | plasmid SOS inhibition protein A | - |
| KDN44_RS24820 (77266) | 77266..77454 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (77266) | 77266..77490 | + | 225 | NuclAT_0 | - | - |
| - (77266) | 77266..77490 | + | 225 | NuclAT_0 | - | - |
| - (77266) | 77266..77490 | + | 225 | NuclAT_0 | - | - |
| - (77266) | 77266..77490 | + | 225 | NuclAT_0 | - | - |
| KDN44_RS25815 (77476) | 77476..77625 | + | 150 | Protein_90 | plasmid maintenance protein Mok | - |
| KDN44_RS24825 (77567) | 77567..77692 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KDN44_RS25820 (77912) | 77912..78142 | + | 231 | WP_071586998.1 | hypothetical protein | - |
| KDN44_RS25825 (78140) | 78140..78312 | - | 173 | Protein_93 | hypothetical protein | - |
| KDN44_RS25830 (78382) | 78382..78588 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| KDN44_RS24830 (78613) | 78613..78900 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| KDN44_RS24835 (79018) | 79018..79839 | + | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| KDN44_RS24840 (80136) | 80136..80726 | - | 591 | WP_001376243.1 | hypothetical protein | VF |
| KDN44_RS24845 (81059) | 81059..81442 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KDN44_RS24850 (81629) | 81629..82318 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| KDN44_RS24855 (82411) | 82411..82812 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| KDN44_RS24860 (82845) | 82845..83210 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| KDN44_RS24865 (83225) | 83225..83536 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KDN44_RS24870 (83558) | 83558..84124 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| KDN44_RS24875 (84111) | 84111..84839 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| KDN44_RS24880 (84839) | 84839..86266 | + | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KDN44_RS24885 (86256) | 86256..86846 | + | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KDN44_RS24890 (86833) | 86833..87030 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| KDN44_RS24895 (87042) | 87042..87293 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| KDN44_RS24900 (87290) | 87290..87805 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KDN44_RS24905 (87940) | 87940..88161 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| KDN44_RS24910 (88321) | 88321..90948 | + | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| KDN44_RS24915 (90945) | 90945..91331 | + | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| KDN44_RS24920 (91328) | 91328..91960 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| KDN44_RS24925 (91957) | 91957..92949 | + | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| KDN44_RS24930 (92958) | 92958..93596 | + | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KDN44_RS24935 (93593) | 93593..95401 | + | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KDN44_RS24940 (95428) | 95428..95685 | + | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| KDN44_RS24945 (95678) | 95678..96421 | + | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KDN44_RS24950 (96437) | 96437..96784 | + | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| KDN44_RS24955 (96786) | 96786..97100 | - | 315 | WP_001324103.1 | hypothetical protein | - |
| KDN44_RS24960 (97181) | 97181..97465 | + | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KDN44_RS24965 (97452) | 97452..97997 | + | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KDN44_RS24970 (97927) | 97927..98268 | + | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| KDN44_RS24975 (98255) | 98255..98635 | + | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| KDN44_RS24980 (98635) | 98635..100008 | + | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| KDN44_RS24985 (100005) | 100005..102827 | + | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KDN44_RS24990 (102843) | 102843..103340 | + | 498 | WP_000605857.1 | entry exclusion protein | - |
| KDN44_RS24995 (103372) | 103372..104103 | + | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| KDN44_RS25000 (104356) | 104356..106509 | + | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| KDN44_RS25005 (106518) | 106518..106916 | - | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KDN44_RS25010 (106916) | 106916..107143 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| KDN44_RS25015 (107225) | 107225..111817 | + | 4593 | Protein_132 | Multifunctional conjugation protein TraI | Relaxase |
| KDN44_RS25020 (111866) | 111866..112570 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KDN44_RS25025 (112746) | 112746..113717 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| KDN44_RS25030 (113717) | 113717..114883 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| KDN44_RS25040 (116365) | 116365..118566 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| KDN44_RS25045 (118592) | 118592..119925 | - | 1334 | Protein_138 | L-lysine N6-monooxygenase | VF |
| KDN44_RS25050 (119922) | 119922..121664 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| KDN44_RS25055 (121664) | 121664..122611 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| KDN44_RS25060 (122612) | 122612..124336 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| KDN44_RS25065 (124472) | 124472..125665 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| KDN44_RS25070 (126045) | 126045..126425 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| KDN44_RS25075 (126766) | 126766..127179 | - | 414 | Protein_144 | phosphopyruvate hydratase | - |
| KDN44_RS25080 (127177) | 127177..127434 | + | 258 | Protein_145 | Tn3 family transposase | - |
| KDN44_RS25085 (127668) | 127668..128525 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| KDN44_RS25090 (128522) | 128522..129379 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| KDN44_RS25095 (129376) | 129376..130203 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| KDN44_RS25100 (130203) | 130203..131117 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| KDN44_RS25105 (131473) | 131473..132170 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| KDN44_RS25110 (132350) | 132350..132863 | - | 514 | Protein_151 | DUF4113 domain-containing protein | - |
| KDN44_RS25115 (132924) | 132924..133028 | - | 105 | Protein_152 | AAA family ATPase | - |
| KDN44_RS25120 (133030) | 133030..133353 | - | 324 | Protein_153 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|