MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 144818 bp
Accession: NZ_CP072977 Location: 1..144818 Organism: Escherichia coli strain EC2341 Replicon: plasmid pEC2341_2
Accession: NZ_CP072977 Location: 1..144818 Organism: Escherichia coli strain EC2341 Replicon: plasmid pEC2341_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KBW65_RS22935 (682) | 682..1782 | - | 1101 | Protein_1 | SDR family oxidoreductase | - |
| KBW65_RS22940 (2185) | 2185..3123 | - | 939 | Protein_2 | omptin family outer membrane protease | - |
| KBW65_RS22945 (3227) | 3227..3616 | + | 390 | WP_032145261.1 | hypothetical protein | - |
| KBW65_RS22950 (4420) | 4420..4599 | - | 180 | Protein_4 | integrase core domain-containing protein | - |
| KBW65_RS22955 (4738) | 4738..5937 | + | 1200 | Protein_5 | IS3 family transposase | - |
| KBW65_RS22960 (6085) | 6085..6410 | - | 326 | Protein_6 | integrase core domain-containing protein | - |
| KBW65_RS25075 (6456) | 6456..6796 | + | 341 | Protein_7 | IS3 family transposase | - |
| KBW65_RS22965 (7391) | 7391..8578 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| KBW65_RS22970 (8575) | 8575..10515 | + | 1941 | WP_000733250.1 | MacB family efflux pump subunit | - |
| KBW65_RS22975 (10519) | 10519..11889 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| KBW65_RS22980 (12363) | 12363..12557 | + | 195 | Protein_11 | IS200/IS605-like element IS200C family transposase | - |
| KBW65_RS22985 (12686) | 12686..13627 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| KBW65_RS22990 (13862) | 13862..15251 | - | 1390 | Protein_13 | ISNCY family transposase | - |
| KBW65_RS22995 (15561) | 15561..15710 | - | 150 | Protein_14 | IS3 family transposase | - |
| KBW65_RS23000 (15888) | 15888..17081 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| KBW65_RS23005 (18323) | 18323..19060 | - | 738 | Protein_16 | IS3 family transposase | - |
| KBW65_RS23010 (19113) | 19113..20275 | + | 1163 | WP_088846059.1 | IS3-like element IS3 family transposase | - |
| KBW65_RS23015 (20292) | 20292..20812 | - | 521 | Protein_18 | IS3-like element IS2 family transposase | - |
| KBW65_RS23020 (21437) | 21437..21730 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| KBW65_RS23025 (21788) | 21788..21987 | - | 200 | Protein_20 | lysis protein | - |
| KBW65_RS23030 (22541) | 22541..23565 | + | 1025 | Protein_21 | integrase core domain-containing protein | - |
| KBW65_RS23035 (24876) | 24876..25991 | + | 1116 | WP_001318220.1 | salmochelin biosynthesis C-glycosyltransferase IroB | - |
| KBW65_RS23040 (26131) | 26131..29790 | + | 3660 | WP_001389363.1 | salmochelin/enterobactin export ABC transporter IroC | - |
| KBW65_RS23045 (29894) | 29894..31123 | + | 1230 | WP_000933678.1 | catecholate siderophore esterase IroD | - |
| KBW65_RS23050 (31208) | 31208..32164 | + | 957 | WP_000271274.1 | catecholate siderophore esterase IroE | - |
| KBW65_RS23055 (32209) | 32209..34386 | - | 2178 | WP_001222186.1 | siderophore salmochelin receptor IroN | - |
| KBW65_RS23060 (35252) | 35252..36286 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| KBW65_RS25080 (36467) | 36467..36768 | + | 302 | Protein_28 | hypothetical protein | - |
| KBW65_RS23065 (36846) | 36846..37139 | - | 294 | WP_000269327.1 | DUF6404 family protein | - |
| KBW65_RS23070 (37307) | 37307..37432 | - | 126 | Protein_30 | type II toxin-antitoxin system toxin YacB | - |
| KBW65_RS23075 (37432) | 37432..37700 | - | 269 | Protein_31 | type II toxin-antitoxin system antitoxin YacA | - |
| KBW65_RS23080 (38311) | 38311..39585 | + | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| KBW65_RS23085 (39578) | 39578..41674 | + | 2097 | WP_000184924.1 | microcin H47 export transporter peptidase/ATP-binding subunit MchF | - |
| KBW65_RS23090 (41844) | 41844..42155 | - | 312 | WP_001259758.1 | colicin V | - |
| KBW65_RS23095 (42133) | 42133..42369 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| KBW65_RS25085 (42488) | 42488..42931 | + | 444 | WP_001323891.1 | dehydrogenase | - |
| KBW65_RS25090 (42903) | 42903..43307 | + | 405 | WP_001389361.1 | hypothetical protein | - |
| KBW65_RS23105 (43309) | 43309..43578 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| KBW65_RS23110 (43575) | 43575..44555 | + | 981 | WP_063099985.1 | NAD(P)-binding domain-containing protein | - |
| KBW65_RS23115 (44610) | 44610..45011 | + | 402 | WP_001309176.1 | transposase | - |
| KBW65_RS23120 (45008) | 45008..45355 | + | 348 | WP_000612591.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| KBW65_RS23125 (45405) | 45405..46265 | + | 861 | Protein_42 | IS66-like element ISEc8 family transposase | - |
| KBW65_RS23130 (46301) | 46301..47599 | - | 1299 | Protein_43 | Tn3-like element Tn3 family transposase | - |
| KBW65_RS23135 (47667) | 47667..48370 | + | 704 | Protein_44 | IS6-like element IS26 family transposase | - |
| KBW65_RS23140 (48564) | 48564..48950 | + | 387 | WP_063102497.1 | bleomycin binding protein | - |
| KBW65_RS23145 (49270) | 49270..49662 | - | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| KBW65_RS23150 (49997) | 49997..50701 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| KBW65_RS23155 (50899) | 50899..51759 | - | 861 | WP_000027057.1 | broad-spectrum class A beta-lactamase TEM-1 | - |
| KBW65_RS23160 (51942) | 51942..52121 | - | 180 | Protein_49 | helix-turn-helix domain-containing protein | - |
| KBW65_RS23165 (52187) | 52187..52891 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KBW65_RS23170 (52925) | 52925..53032 | - | 108 | WP_135267217.1 | EAL domain-containing protein | - |
| KBW65_RS23175 (53235) | 53235..54248 | - | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| KBW65_RS23180 (54406) | 54406..54879 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| KBW65_RS23185 (54953) | 54953..55657 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| KBW65_RS23190 (55759) | 55759..56238 | + | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| KBW65_RS23195 (56308) | 56308..59460 | - | 3153 | WP_000347934.1 | multidrug efflux RND transporter permease subunit OqxB | - |
| KBW65_RS23200 (59484) | 59484..60659 | - | 1176 | WP_002914189.1 | multidrug efflux RND transporter periplasmic adaptor subunit OqxA | - |
| KBW65_RS23205 (60979) | 60979..61683 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| KBW65_RS23210 (61737) | 61737..62264 | + | 528 | Protein_59 | IS4-like element ISVsa5 family transposase | - |
| KBW65_RS23215 (62274) | 62274..62690 | - | 417 | WP_000275180.1 | AraC family transcriptional regulator | - |
| KBW65_RS23220 (62778) | 62778..63371 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| KBW65_RS23225 (63484) | 63484..64689 | - | 1206 | WP_001089068.1 | tetracycline efflux MFS transporter Tet(B) | - |
| KBW65_RS23230 (64771) | 64771..65394 | + | 624 | WP_000088605.1 | tetracycline resistance transcriptional repressor TetR(B) | - |
| KBW65_RS23235 (65372) | 65372..66058 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| KBW65_RS23240 (66066) | 66066..66452 | - | 387 | WP_000460653.1 | hypothetical protein | - |
| KBW65_RS23245 (66445) | 66445..66765 | - | 321 | WP_000562367.1 | antibiotic biosynthesis monooxygenase | - |
| KBW65_RS23250 (67209) | 67209..68414 | + | 1206 | WP_000599533.1 | sodium/glutamate symporter | - |
| KBW65_RS23255 (68645) | 68645..68764 | + | 120 | Protein_68 | LysR family transcriptional regulator | - |
| KBW65_RS23260 (68780) | 68780..69988 | - | 1209 | WP_001352368.1 | IS4-like element ISVsa5 family transposase | - |
| KBW65_RS23265 (70149) | 70149..70808 | + | 660 | WP_000412211.1 | type A-1 chloramphenicol O-acetyltransferase | - |
| KBW65_RS23270 (71009) | 71009..71386 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| KBW65_RS23275 (71561) | 71561..72265 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KBW65_RS23280 (72320) | 72320..72745 | + | 426 | Protein_73 | TetR/AcrR family transcriptional regulator | - |
| KBW65_RS23285 (72765) | 72765..73554 | + | 790 | Protein_74 | winged helix-turn-helix domain-containing protein | - |
| KBW65_RS23290 (73554) | 73554..74072 | + | 519 | WP_014839979.1 | FidL-like protein | - |
| KBW65_RS23295 (74077) | 74077..74493 | - | 417 | WP_014839980.1 | fosfomycin resistance glutathione transferase FosA3 | - |
| KBW65_RS23300 (74879) | 74879..75583 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KBW65_RS23305 (75635) | 75635..76534 | - | 900 | Protein_78 | IS5-like element IS903B family transposase | - |
| KBW65_RS23310 (76569) | 76569..77444 | - | 876 | WP_013188475.1 | extended-spectrum class A beta-lactamase CTX-M-65 | - |
| KBW65_RS23315 (77694) | 77694..77885 | - | 192 | Protein_80 | IS1380 family transposase | - |
| KBW65_RS23320 (77949) | 77949..78575 | - | 627 | WP_000434930.1 | hypothetical protein | - |
| KBW65_RS23325 (78575) | 78575..81832 | - | 3258 | WP_210833289.1 | MobF family relaxase | - |
| KBW65_RS23330 (81857) | 81857..82561 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KBW65_RS23335 (82611) | 82611..83330 | + | 720 | Protein_84 | helicase RepA family protein | - |
| KBW65_RS23340 (83317) | 83317..84168 | + | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| KBW65_RS23345 (84475) | 84475..85290 | + | 816 | WP_001043265.1 | sulfonamide-resistant dihydropteroate synthase Sul2 | - |
| KBW65_RS23350 (85351) | 85351..86154 | + | 804 | WP_001082319.1 | aminoglycoside O-phosphotransferase APH(3'')-Ib | - |
| KBW65_RS23355 (86154) | 86154..86990 | + | 837 | WP_000480968.1 | aminoglycoside O-phosphotransferase APH(6)-Id | - |
| KBW65_RS23360 (87051) | 87051..87755 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KBW65_RS23365 (87906) | 87906..88721 | + | 816 | WP_000018329.1 | aminoglycoside O-phosphotransferase APH(3')-Ia | - |
| KBW65_RS23370 (88911) | 88911..89039 | - | 129 | Protein_91 | IS6 family transposase | - |
| KBW65_RS23380 (90002) | 90002..90403 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KBW65_RS23385 (90336) | 90336..90593 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KBW65_RS25095 (90686) | 90686..90970 | - | 285 | WP_223364261.1 | CPBP family intramembrane metalloprotease | - |
| KBW65_RS25100 (90936) | 90936..91328 | - | 393 | WP_000616804.1 | histidine phosphatase family protein | - |
| KBW65_RS23395 (92267) | 92267..93124 | - | 858 | WP_032152935.1 | incFII family plasmid replication initiator RepA | - |
| KBW65_RS23400 (93117) | 93117..93191 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| KBW65_RS23405 (93426) | 93426..93683 | - | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| KBW65_RS23410 (94088) | 94088..95110 | + | 1023 | WP_000156883.1 | IS110 family transposase | - |
| KBW65_RS23415 (95582) | 95582..95935 | + | 354 | WP_000005489.1 | hypothetical protein | - |
| KBW65_RS23420 (96348) | 96348..96926 | - | 579 | WP_032152936.1 | DUF2726 domain-containing protein | - |
| KBW65_RS23425 (96959) | 96959..97656 | + | 698 | WP_223230354.1 | IS1-like element IS1A family transposase | - |
| KBW65_RS23430 (97771) | 97771..98127 | + | 357 | WP_000229735.1 | transposase | - |
| KBW65_RS23435 (98124) | 98124..98474 | + | 351 | WP_000624725.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| KBW65_RS23440 (98505) | 98505..98726 | + | 222 | WP_000080227.1 | hypothetical protein | - |
| KBW65_RS23445 (98678) | 98678..99019 | + | 342 | Protein_107 | transposase | - |
| KBW65_RS23450 (99083) | 99083..99562 | - | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| KBW65_RS23455 (99643) | 99643..101046 | - | 1404 | WP_000514417.1 | YfcC family protein | - |
| KBW65_RS23460 (101094) | 101094..102098 | - | 1005 | WP_000154545.1 | ornithine carbamoyltransferase | - |
| KBW65_RS23465 (102183) | 102183..103094 | - | 912 | WP_000440183.1 | carbamate kinase | - |
| KBW65_RS23470 (103105) | 103105..104325 | - | 1221 | WP_000410951.1 | arginine deiminase | - |
| KBW65_RS23475 (105032) | 105032..105646 | + | 615 | Protein_113 | VENN motif pre-toxin domain-containing protein | - |
| KBW65_RS23480 (105646) | 105646..106092 | - | 447 | Protein_114 | plasmid replication initiator RepA | - |
| KBW65_RS23485 (106085) | 106085..106159 | - | 75 | WP_032336874.1 | RepA leader peptide Tap | - |
| KBW65_RS23490 (106395) | 106395..106652 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| KBW65_RS23495 (106936) | 106936..107085 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (107129) | 107129..107190 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (107129) | 107129..107190 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (107129) | 107129..107190 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (107129) | 107129..107190 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| KBW65_RS23500 (107329) | 107329..107511 | - | 183 | WP_000968309.1 | hypothetical protein | - |
| KBW65_RS23505 (107612) | 107612..108240 | + | 629 | Protein_119 | IS1-like element IS1A family transposase | - |
| KBW65_RS25105 (108307) | 108307..108654 | - | 348 | Protein_120 | antirestriction protein | - |
| KBW65_RS23515 (109068) | 109068..109838 | - | 771 | WP_001006251.1 | hypothetical protein | - |
| KBW65_RS23520 (109883) | 109883..110401 | - | 519 | WP_223349485.1 | DUF1380 family protein | - |
| KBW65_RS23525 (110331) | 110331..110552 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| KBW65_RS23530 (110553) | 110553..111236 | - | 684 | WP_032181561.1 | DNA methylase | - |
| KBW65_RS23535 (111313) | 111313..111624 | - | 312 | WP_012615291.1 | hypothetical protein | - |
| KBW65_RS23540 (111621) | 111621..112523 | - | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| KBW65_RS23545 (113261) | 113261..114232 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| KBW65_RS23550 (114232) | 114232..115398 | - | 1167 | WP_000772446.1 | plasmid-partitioning protein SopA | - |
| KBW65_RS23555 (115986) | 115986..116741 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| KBW65_RS23560 (117463) | 117463..118269 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| KBW65_RS23565 (118270) | 118270..118575 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| KBW65_RS23570 (118577) | 118577..118795 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| KBW65_RS23575 (119355) | 119355..119585 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KBW65_RS23580 (119582) | 119582..119998 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KBW65_RS23585 (120073) | 120073..121638 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| KBW65_RS23590 (121623) | 121623..122645 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| KBW65_RS23595 (122899) | 122899..123585 | - | 687 | Protein_137 | IS1 family transposase | - |
| KBW65_RS23600 (124111) | 124111..126312 | - | 2202 | WP_000973519.1 | ferric aerobactin receptor IutA | - |
| KBW65_RS23605 (126338) | 126338..127671 | - | 1334 | Protein_139 | NADPH-dependent L-lysine N(6)-monooxygenase IucD | - |
| KBW65_RS23610 (127668) | 127668..129410 | - | 1743 | WP_001015721.1 | NIS family aerobactin synthetase IucC | - |
| KBW65_RS23615 (129410) | 129410..130357 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase IucB | - |
| KBW65_RS23620 (130358) | 130358..132082 | - | 1725 | WP_000602863.1 | NIS family aerobactin synthetase IucA | - |
| KBW65_RS23625 (132218) | 132218..133411 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| KBW65_RS23630 (133791) | 133791..134171 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| KBW65_RS23635 (134512) | 134512..134925 | - | 414 | Protein_145 | phosphopyruvate hydratase | - |
| KBW65_RS23640 (134923) | 134923..135180 | + | 258 | Protein_146 | Tn3 family transposase | - |
| KBW65_RS23645 (135414) | 135414..136271 | - | 858 | WP_000968139.1 | iron/manganese ABC transporter permease subunit SitD | - |
| KBW65_RS23650 (136268) | 136268..137125 | - | 858 | WP_001101723.1 | iron/manganese ABC transporter permease subunit SitC | - |
| KBW65_RS23655 (137122) | 137122..137949 | - | 828 | WP_000983710.1 | iron/manganese ABC transporter ATP-binding protein SitB | - |
| KBW65_RS23660 (137949) | 137949..138863 | - | 915 | WP_000949005.1 | iron/manganese ABC transporter substrate-binding protein SitA | - |
| KBW65_RS23665 (139219) | 139219..139916 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| KBW65_RS23670 (140096) | 140096..140609 | - | 514 | Protein_152 | DUF4113 domain-containing protein | - |
| KBW65_RS23675 (140670) | 140670..140774 | - | 105 | Protein_153 | AAA family ATPase | - |
| KBW65_RS23680 (140776) | 140776..141099 | - | 324 | Protein_154 | helix-turn-helix domain-containing protein | - |
| KBW65_RS23685 (141845) | 141845..142822 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| KBW65_RS23690 (143107) | 143107..143847 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| KBW65_RS23695 (143968) | 143968..144156 | - | 189 | WP_073056885.1 | serine/threonine protein kinase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|