MGE detailed information
MGE type: Mobilizable plasmid MGE length: 136429 bp
Accession: NZ_CP069974 Location: 1..136429 Organism: Escherichia coli strain FDAARGOS_1280 Replicon: plasmid unnamed4
Accession: NZ_CP069974 Location: 1..136429 Organism: Escherichia coli strain FDAARGOS_1280 Replicon: plasmid unnamed4
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6K10_RS25735 (422) | 422..1693 | - | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| I6K10_RS25740 (1690) | 1690..3246 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| I6K10_RS25745 (3429) | 3429..3650 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| I6K10_RS25750 (3650) | 3650..4030 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| I6K10_RS25755 (4035) | 4035..4214 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| I6K10_RS25760 (4242) | 4242..4520 | + | 279 | Protein_6 | pdcB | - |
| I6K10_RS25765 (4525) | 4525..4938 | + | 414 | Protein_7 | IS3 family transposase ISLad1 | Transposase |
| I6K10_RS25770 (5734) | 5734..6711 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| I6K10_RS25775 (6996) | 6996..7736 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| I6K10_RS25780 (7857) | 7857..8039 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| I6K10_RS27160 (8106) | 8106..8395 | - | 290 | Protein_11 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| I6K10_RS25785 (8382) | 8382..8650 | - | 269 | Protein_12 | type II toxin-antitoxin system ParD family antitoxin | - |
| I6K10_RS25790 (9182) | 9182..10351 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| I6K10_RS25795 (10384) | 10384..10512 | + | 129 | Protein_14 | IS481 family transposase | - |
| I6K10_RS25800 (10547) | 10547..10735 | - | 189 | Protein_15 | hypothetical protein | - |
| I6K10_RS25805 (10783) | 10783..11480 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| I6K10_RS25810 (11492) | 11492..11599 | + | 108 | Protein_17 | transcriptional regulator | - |
| I6K10_RS25815 (11577) | 11577..12200 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| I6K10_RS25820 (12282) | 12282..13487 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| I6K10_RS25825 (13600) | 13600..14193 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| I6K10_RS25830 (14281) | 14281..14697 | + | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| I6K10_RS25835 (14707) | 14707..15228 | - | 522 | Protein_22 | IS4 family transposase IS10R | Transposase |
| I6K10_RS25840 (15235) | 15235..15423 | - | 189 | Protein_23 | IS1 family transposase | - |
| I6K10_RS25845 (15488) | 15488..16192 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| I6K10_RS25850 (16238) | 16238..16885 | - | 648 | Protein_25 | IS91 family transposase ISAzo26 | Transposase |
| I6K10_RS25855 (17043) | 17043..17516 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| I6K10_RS25860 (17647) | 17647..18435 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| I6K10_RS25865 (18641) | 18641..18988 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| I6K10_RS25870 (18982) | 18982..19821 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| I6K10_RS25875 (19949) | 19949..20152 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| I6K10_RS25880 (20308) | 20308..20673 | + | 366 | Protein_31 | chromate transporter | - |
| I6K10_RS25885 (20727) | 20727..21431 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| I6K10_RS25890 (21607) | 21607..21888 | - | 282 | Protein_33 | transposase zinc-binding domain-containing protein | - |
| I6K10_RS25895 (22035) | 22035..22895 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| I6K10_RS25900 (23078) | 23078..23416 | - | 339 | Protein_35 | Tn3 family transposase TnpR_Tn3 | Transposase |
| I6K10_RS25905 (23480) | 23480..24184 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| I6K10_RS27165 (24239) | 24239..24310 | + | 72 | Protein_37 | hypothetical protein | - |
| I6K10_RS25910 (24566) | 24566..25441 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| I6K10_RS25915 (25488) | 25488..25820 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| I6K10_RS25920 (25846) | 25846..28629 | + | 2784 | Protein_40 | Tn3 family transposase TnpA_Tn3 | Transposase |
| I6K10_RS25925 (28672) | 28672..29687 | - | 1016 | Protein_41 | IS3 family transposase ISEc36 | Transposase |
| I6K10_RS25930 (30082) | 30082..30738 | + | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| I6K10_RS25935 (31057) | 31057..31485 | - | 429 | Protein_43 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| I6K10_RS25940 (31518) | 31518..32909 | - | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| I6K10_RS25945 (32946) | 32946..33518 | - | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| I6K10_RS25950 (33655) | 33655..34200 | - | 546 | WP_001493763.1 | plasmid pRiA4b ORF-3 family protein | - |
| I6K10_RS25955 (34335) | 34335..34496 | - | 162 | Protein_47 | type II toxin-antitoxin system mRNA interferase RelE | - |
| I6K10_RS25960 (34496) | 34496..34735 | - | 240 | WP_000534857.1 | type II toxin-antitoxin system antitoxin RelB | - |
| I6K10_RS27170 (34760) | 34760..34887 | + | 128 | Protein_49 | hypothetical protein | - |
| I6K10_RS25965 (34967) | 34967..35929 | + | 963 | WP_014639476.1 | hypothetical protein | - |
| I6K10_RS25970 (35945) | 35945..36946 | + | 1002 | WP_000354966.1 | hypothetical protein | - |
| I6K10_RS25975 (37285) | 37285..37989 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6K10_RS25980 (38312) | 38312..39796 | - | 1485 | WP_032152108.1 | IS91 family transposase ISVsa3 | Transposase |
| I6K10_RS25985 (40071) | 40071..40412 | - | 342 | WP_023909256.1 | 60 kDa chaperonin 2 | VF |
| I6K10_RS25990 (40373) | 40373..40822 | - | 450 | WP_013362817.1 | hypothetical protein | - |
| I6K10_RS26000 (41452) | 41452..42189 | - | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| I6K10_RS26005 (42315) | 42315..42410 | - | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| I6K10_RS26010 (42545) | 42545..43249 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6K10_RS26015 (43371) | 43371..44276 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| I6K10_RS26020 (44273) | 44273..45511 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| I6K10_RS26025 (45511) | 45511..46095 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| I6K10_RS26030 (46588) | 46588..47352 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| I6K10_RS26035 (47470) | 47470..47535 | - | 66 | Protein_63 | EAL domain-containing protein | - |
| I6K10_RS26040 (47579) | 47579..47884 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| I6K10_RS26045 (47895) | 47895..49100 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| I6K10_RS26050 (49256) | 49256..49459 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| I6K10_RS26055 (49587) | 49587..50426 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| I6K10_RS26060 (50420) | 50420..50767 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| I6K10_RS26065 (50973) | 50973..51761 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| I6K10_RS26070 (51892) | 51892..52365 | - | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| I6K10_RS26075 (52523) | 52523..53152 | + | 630 | Protein_71 | IS91 family transposase ISAzo26 | Transposase |
| I6K10_RS26080 (53217) | 53217..53921 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6K10_RS26085 (53987) | 53987..54532 | + | 546 | Protein_73 | Tn3 family transposase TnpA_Tn3 | Transposase |
| I6K10_RS26090 (54568) | 54568..54983 | - | 416 | Protein_74 | IS1-like element IS1B family transposase | - |
| I6K10_RS26095 (55232) | 55232..55633 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| I6K10_RS26100 (55566) | 55566..55823 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| I6K10_RS26105 (55916) | 55916..56569 | - | 654 | WP_052929223.1 | type II CAAX endopeptidase family protein | - |
| I6K10_RS26110 (56667) | 56667..56807 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| I6K10_RS26115 (57509) | 57509..58366 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| I6K10_RS26120 (58359) | 58359..58433 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| I6K10_RS26130 (58795) | 58795..60336 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| I6K10_RS26135 (60351) | 60351..61097 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| I6K10_RS26140 (61257) | 61257..61511 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| I6K10_RS26145 (61808) | 61808..61942 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (61987) | 61987..62047 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (61987) | 61987..62047 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (61987) | 61987..62047 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (61987) | 61987..62047 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| I6K10_RS26150 (62014) | 62014..62300 | - | 287 | Protein_85 | DUF2726 domain-containing protein | - |
| I6K10_RS26155 (62813) | 62813..63025 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| I6K10_RS26160 (63156) | 63156..63716 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| I6K10_RS26165 (63771) | 63771..64517 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| I6K10_RS26170 (64537) | 64537..66993 | - | 2457 | Protein_89 | Multifunctional conjugation protein TraI | Relaxase |
| I6K10_RS26175 (67054) | 67054..67758 | + | 705 | WP_001067858.1 | Multifunctional conjugation protein TraI | Relaxase |
| I6K10_RS26180 (67813) | 67813..68658 | - | 846 | Protein_91 | IS4 family transposase IS10R | Transposase |
| I6K10_RS26185 (68768) | 68768..69730 | - | 963 | Protein_92 | IS4 family transposase IS10R | Transposase |
| I6K10_RS26190 (69873) | 69873..70733 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| I6K10_RS26195 (70746) | 70746..71288 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| I6K10_RS26200 (71770) | 71770..71961 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| I6K10_RS26205 (71985) | 71985..72212 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| I6K10_RS26210 (72263) | 72263..73390 | + | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| I6K10_RS26215 (73427) | 73427..74131 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| I6K10_RS26220 (74186) | 74186..76912 | - | 2727 | Protein_99 | Multifunctional conjugation protein TraI | Relaxase |
| I6K10_RS26225 (76902) | 76902..77075 | - | 174 | Protein_100 | type IV secretion system DNA-binding domain-containing protein | - |
| I6K10_RS26230 (77074) | 77074..77238 | - | 165 | Protein_101 | TraU family protein | - |
| I6K10_RS26235 (77235) | 77235..77579 | - | 345 | Protein_102 | conjugal transfer protein TraW | - |
| I6K10_RS26240 (77575) | 77575..79896 | - | 2322 | Protein_103 | type IV secretion system protein TraC | - |
| I6K10_RS26245 (80056) | 80056..80277 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| I6K10_RS26250 (80412) | 80412..80927 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| I6K10_RS26255 (80927) | 80927..81238 | - | 312 | WP_001057272.1 | conjugal transfer protein TrbD | - |
| I6K10_RS26260 (81225) | 81225..81791 | - | 567 | WP_000896601.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| I6K10_RS26265 (81781) | 81781..83232 | - | 1452 | WP_000146687.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| I6K10_RS26270 (83232) | 83232..83960 | - | 729 | WP_001230808.1 | type-F conjugative transfer system secretin TraK | - |
| I6K10_RS26275 (83947) | 83947..84513 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| I6K10_RS26280 (84535) | 84535..84846 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| I6K10_RS26285 (84851) | 84851..85213 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| I6K10_RS26290 (85247) | 85247..85474 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| I6K10_RS26295 (85562) | 85562..86239 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| I6K10_RS26300 (86373) | 86373..86756 | - | 384 | WP_001151566.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| I6K10_RS26305 (87099) | 87099..87689 | + | 591 | WP_001376243.1 | hypothetical protein | VF |
| I6K10_RS26310 (87986) | 87986..88807 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| I6K10_RS26315 (88926) | 88926..89213 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| I6K10_RS26320 (89238) | 89238..89444 | - | 207 | WP_024190427.1 | hypothetical protein | - |
| I6K10_RS27175 (89514) | 89514..89687 | + | 174 | Protein_120 | hypothetical protein | - |
| I6K10_RS26325 (90416) | 90416..92083 | + | 1668 | WP_052991863.1 | group II intron reverse transcriptase/maturase | - |
| I6K10_RS26330 (92478) | 92478..92603 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| I6K10_RS27180 (92545) | 92545..92694 | - | 150 | Protein_123 | plasmid maintenance protein Mok | - |
| - (92680) | 92680..92718 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (92680) | 92680..92718 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (92680) | 92680..92718 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (92680) | 92680..92718 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (94158) | 94158..94260 | - | 103 | NuclAT_0 | - | - |
| - (94158) | 94158..94260 | - | 103 | NuclAT_0 | - | - |
| - (94158) | 94158..94260 | - | 103 | NuclAT_0 | - | - |
| - (94158) | 94158..94260 | - | 103 | NuclAT_0 | - | - |
| I6K10_RS26340 (94229) | 94229..94991 | - | 763 | Protein_125 | plasmid SOS inhibition protein A | - |
| I6K10_RS26345 (94988) | 94988..95422 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| I6K10_RS26350 (95477) | 95477..97435 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| I6K10_RS26355 (97501) | 97501..97734 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| I6K10_RS26360 (97797) | 97797..98294 | - | 498 | WP_042045560.1 | single-stranded DNA-binding protein | - |
| I6K10_RS26365 (98444) | 98444..100345 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| I6K10_RS27185 (101023) | 101023..101229 | - | 207 | WP_000547975.1 | hypothetical protein | - |
| I6K10_RS27190 (101299) | 101299..101472 | + | 174 | Protein_132 | hypothetical protein | - |
| I6K10_RS26370 (102201) | 102201..103868 | + | 1668 | WP_052991863.1 | group II intron reverse transcriptase/maturase | - |
| I6K10_RS27195 (103981) | 103981..104136 | + | 156 | Protein_134 | hypothetical protein | - |
| I6K10_RS26380 (104221) | 104221..104784 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| I6K10_RS26385 (104832) | 104832..106193 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| I6K10_RS26390 (106245) | 106245..106475 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| I6K10_RS27200 (106989) | 106989..107143 | + | 155 | Protein_138 | hypothetical protein | - |
| I6K10_RS26395 (107872) | 107872..109539 | + | 1668 | WP_204638473.1 | group II intron reverse transcriptase/maturase | - |
| I6K10_RS26400 (109853) | 109853..110044 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| I6K10_RS26405 (110041) | 110041..110463 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| I6K10_RS26410 (110510) | 110510..110935 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| I6K10_RS26415 (111352) | 111352..112128 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| I6K10_RS26420 (112179) | 112179..112697 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| I6K10_RS26425 (112627) | 112627..112848 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| I6K10_RS26430 (112849) | 112849..113532 | - | 684 | WP_000086185.1 | DNA methylase | - |
| I6K10_RS26435 (113609) | 113609..113920 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| I6K10_RS26440 (113917) | 113917..114819 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| I6K10_RS26445 (115686) | 115686..116657 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| I6K10_RS26450 (116657) | 116657..117823 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| I6K10_RS26455 (118411) | 118411..119166 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| I6K10_RS26460 (119940) | 119940..120746 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| I6K10_RS26465 (120747) | 120747..121052 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| I6K10_RS26470 (121054) | 121054..121272 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| I6K10_RS26475 (121906) | 121906..122103 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| I6K10_RS26480 (122100) | 122100..122384 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| I6K10_RS26485 (122404) | 122404..123537 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| I6K10_RS26490 (123800) | 123800..126919 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| I6K10_RS26495 (127226) | 127226..127456 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| I6K10_RS26500 (127453) | 127453..127869 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| I6K10_RS26505 (128031) | 128031..130169 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| I6K10_RS26510 (130634) | 130634..131629 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| I6K10_RS26515 (131633) | 131633..132565 | + | 933 | WP_000991832.1 | S-4TM family putative pore-forming effector | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|