MGE detailed information

MGE type: Conjugative plasmid        MGE length: 146908 bp
Accession: NZ_CP069678        Location: 1..146908         Organism: Escherichia coli O126:H45 strain MIN10       Replicon: plasmid pMUB-MIN10-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JSU12_RS24900 (1) 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
JSU12_RS24905 (1263) 1263..2003 - 741 WP_001066954.1 tyrosine-type recombinase/integrase -
JSU12_RS24910 (2124) 2124..2312 - 189 WP_001324033.1 hypothetical protein -
JSU12_RS24915 (2686) 2686..3588 - 903 WP_001312822.1 hypothetical protein VF
JSU12_RS24920 (3657) 3657..4766 - 1110 WP_000771475.1 SDR family oxidoreductase -
JSU12_RS24925 (5199) 5199..6152 - 954 WP_000280980.1 Protease 7 VF
JSU12_RS24930 (7449) 7449..7628 - 180 Protein_6 integrase core domain-containing protein -
JSU12_RS24935 (7767) 7767..8966 + 1200 Protein_7 IS3 family transposase IS629 Transposase
JSU12_RS24940 (9114) 9114..9439 - 326 Protein_8 IS3 family transposase ISLad1 Transposase
JSU12_RS26815 (9485) 9485..9825 + 341 Protein_9 IS3 family transposase -
JSU12_RS24945 (10420) 10420..11607 + 1188 WP_000928804.1 efflux RND transporter periplasmic adaptor subunit -
JSU12_RS24950 (11604) 11604..13544 + 1941 WP_000733250.1 Macrolide export ATP-binding/permease protein MacB VF
JSU12_RS24955 (13548) 13548..14918 + 1371 WP_001312828.1 efflux transporter outer membrane subunit -
JSU12_RS24960 (15392) 15392..15586 + 195 Protein_13 IS200/IS605-like element IS200C family transposase -
JSU12_RS24965 (15715) 15715..16656 - 942 WP_000974762.1 hypothetical protein -
JSU12_RS24970 (16891) 16891..18280 - 1390 Protein_15 ISNCY family transposase ISKpn21 Transposase
JSU12_RS24975 (18590) 18590..18739 - 150 Protein_16 IS3 family transposase IS2 Transposase
JSU12_RS24980 (18917) 18917..20110 - 1194 WP_000450494.1 GTP-binding protein -
JSU12_RS24985 (21352) 21352..22089 - 738 Protein_18 IS3 family transposase IS2 Transposase
JSU12_RS24990 (22142) 22142..23304 + 1163 WP_088846059.1 IS3 family transposase ISEc17 Transposase
JSU12_RS24995 (23321) 23321..23841 - 521 Protein_20 IS3 family transposase IS2 Transposase
JSU12_RS25000 (24380) 24380..25588 - 1209 WP_001352368.1 IS4 family transposase IS10R Transposase
JSU12_RS25005 (25804) 25804..26097 + 294 WP_000738422.1 increased serum survival lipoprotein Iss -
JSU12_RS25010 (26155) 26155..26354 - 200 Protein_23 lysis protein -
JSU12_RS25015 (26908) 26908..27932 + 1025 Protein_24 integrase core domain-containing protein -
JSU12_RS25020 (29243) 29243..30358 + 1116 WP_001318220.1 Elloramycin glycosyltransferase ElmGT VF
JSU12_RS25025 (30498) 30498..34157 + 3660 WP_175101087.1 Multidrug efflux ATP-binding/permease protein VF
JSU12_RS25030 (34261) 34261..35490 + 1230 WP_000933678.1 Enterochelin esterase VF
JSU12_RS25035 (35575) 35575..36531 + 957 WP_000271274.1 Ferri-bacillibactin esterase BesA VF
JSU12_RS25040 (36576) 36576..38753 - 2178 WP_001222186.1 Ferric enterobactin receptor VF
JSU12_RS25045 (39619) 39619..40653 - 1035 WP_001190234.1 3-deoxy-7-phosphoheptulonate synthase -
JSU12_RS26820 (40834) 40834..41135 + 302 Protein_31 hypothetical protein -
JSU12_RS25050 (41213) 41213..41521 - 309 WP_000377483.1 DUF6404 family protein -
JSU12_RS25055 (41674) 41674..41799 - 126 Protein_33 type II toxin-antitoxin system toxin YacB -
JSU12_RS25060 (41799) 41799..42067 - 269 Protein_34 type II toxin-antitoxin system antitoxin YacA -
JSU12_RS25065 (42678) 42678..43952 + 1275 WP_000489609.1 HlyD family secretion protein -
JSU12_RS25070 (43945) 43945..46041 + 2097 WP_000184924.1 microcin H47 export transporter peptidase/ATP-binding subunit MchF -
JSU12_RS25075 (46274) 46274..47482 + 1209 WP_001352368.1 IS4 family transposase IS10R Transposase
JSU12_RS25080 (47549) 47549..47860 - 312 WP_001259758.1 colicin V -
JSU12_RS25085 (47838) 47838..48074 - 237 WP_001323890.1 colicin V immunity protein -
JSU12_RS26825 (48193) 48193..48636 + 444 WP_001323891.1 dehydrogenase -
JSU12_RS26830 (48608) 48608..49012 + 405 WP_001389361.1 hypothetical protein -
JSU12_RS25095 (49014) 49014..49283 + 270 WP_000379710.1 SemiSWEET transporter -
JSU12_RS25100 (49280) 49280..50260 + 981 WP_001017346.1 NAD(P)-binding domain-containing protein -
JSU12_RS25105 (50336) 50336..50716 + 381 WP_001171523.1 IS66 family transposase ISEc8 Transposase
JSU12_RS25110 (50713) 50713..51060 + 348 WP_000612591.1 IS66 family transposase ISEc8 Transposase
JSU12_RS25115 (51110) 51110..51970 + 861 Protein_46 IS66 family transposase ISEc8 Transposase
JSU12_RS25120 (52006) 52006..55011 - 3006 WP_001143760.1 Tn3 family transposase TnpA_Tn3 Transposase
JSU12_RS25125 (55175) 55175..55732 + 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
JSU12_RS25130 (55915) 55915..56775 + 861 WP_000027057.1 Beta-lactamase TEM ARG
JSU12_RS25135 (56936) 56936..57433 + 498 Protein_50 mercuric reductase -
JSU12_RS25140 (57451) 57451..57813 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
JSU12_RS25145 (57810) 57810..58046 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
JSU12_RS25150 (58082) 58082..58750 + 669 WP_001300294.1 putative signaling protein VF
JSU12_RS25155 (58825) 58825..60075 + 1251 Protein_54 transposase -
JSU12_RS25160 (60140) 60140..60844 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JSU12_RS25165 (60899) 60899..61156 + 258 Protein_56 hypothetical protein -
JSU12_RS25170 (61302) 61302..62165 + 864 WP_000612791.1 SDR family oxidoreductase -
JSU12_RS25175 (62203) 62203..62448 + 246 WP_001354008.1 GrpB family protein -
JSU12_RS25180 (62917) 62917..63708 + 792 WP_000034420.1 Dihydropteroate synthase ARG
JSU12_RS25185 (63711) 63711..63986 - 276 WP_109023896.1 hypothetical protein -
JSU12_RS25190 (64009) 64009..64641 + 633 WP_020802982.1 IS256 family transposase IS406 Transposase
JSU12_RS25195 (64888) 64888..65220 - 333 WP_000800531.1 quaternary ammonium compound efflux SMR transporter QacL -
JSU12_RS25200 (65343) 65343..66181 - 839 Protein_63 Streptomycin 3''-adenylyltransferase ARG
JSU12_RS25205 (66274) 66274..66747 - 474 WP_000777555.1 Dihydrofolate reductase type 1 ARG
JSU12_RS25210 (66903) 66903..67916 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
JSU12_RS25215 (68119) 68119..68469 + 351 WP_000454193.1 DUF3330 domain-containing protein -
JSU12_RS25220 (68645) 68645..69205 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
JSU12_RS25225 (69209) 69209..72175 + 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
JSU12_RS25230 (72233) 72233..72475 + 243 WP_208207902.1 relaxase -
JSU12_RS25235 (72507) 72507..73157 - 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
JSU12_RS25240 (73263) 73263..74462 + 1200 WP_001493765.1 Tetracycline resistance protein, class C ARG
JSU12_RS25245 (74494) 74494..75378 - 885 WP_000058717.1 EamA family transporter -
JSU12_RS25250 (75516) 75516..75908 - 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
JSU12_RS25255 (75912) 75912..76247 + 336 Protein_74 Tn3 family transposase -
JSU12_RS25260 (76301) 76301..77005 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JSU12_RS25265 (77051) 77051..77203 + 153 Protein_76 IS4 family transposase -
JSU12_RS25270 (77363) 77363..77764 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
JSU12_RS25275 (77697) 77697..77954 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
JSU12_RS25280 (78047) 78047..78700 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
JSU12_RS25285 (78798) 78798..78938 - 141 WP_001333237.1 hypothetical protein -
JSU12_RS25290 (79639) 79639..80496 - 858 WP_000774297.1 incFII family plasmid replication initiator RepA -
JSU12_RS25295 (80489) 80489..80971 - 483 WP_001273588.1 hypothetical protein -
JSU12_RS26835 (80964) 80964..81011 - 48 WP_229471593.1 hypothetical protein -
JSU12_RS26840 (81002) 81002..81253 + 252 WP_223195197.1 replication protein RepA -
JSU12_RS25305 (81270) 81270..81527 - 258 WP_000083845.1 replication regulatory protein RepA -
JSU12_RS25310 (81811) 81811..81960 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (82004) 82004..82065 + 62 NuclAT_1 - Antitoxin Detail
- (82004) 82004..82065 + 62 NuclAT_1 - Antitoxin Detail
- (82004) 82004..82065 + 62 NuclAT_1 - Antitoxin Detail
- (82004) 82004..82065 + 62 NuclAT_1 - Antitoxin Detail
JSU12_RS25315 (82321) 82321..82395 - 75 Protein_87 endonuclease -
JSU12_RS25320 (82641) 82641..82853 - 213 WP_001299730.1 ANR family transcriptional regulator -
JSU12_RS25325 (82989) 82989..83549 - 561 WP_000139315.1 fertility inhibition protein FinO -
JSU12_RS25330 (83652) 83652..84512 - 861 WP_000704514.1 putative protein YcjY VF
JSU12_RS25335 (84571) 84571..85317 - 747 WP_000205749.1 conjugal transfer pilus acetylase TraX -
JSU12_RS25340 (85337) 85337..90607 - 5271 WP_000986962.1 Multifunctional conjugation protein TraI Relaxase
JSU12_RS25345 (90689) 90689..90916 + 228 WP_000450520.1 toxin-antitoxin system antitoxin VapB -
JSU12_RS25350 (90916) 90916..91314 + 399 WP_000911313.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
JSU12_RS25355 (91323) 91323..93476 - 2154 WP_000009324.1 type IV conjugative transfer system coupling protein TraD -
JSU12_RS25360 (93729) 93729..94460 - 732 WP_023565183.1 conjugal transfer complement resistance protein TraT -
JSU12_RS25365 (94492) 94492..94989 - 498 WP_000605857.1 entry exclusion protein -
JSU12_RS25370 (95005) 95005..97827 - 2823 WP_001007018.1 conjugal transfer mating-pair stabilization protein TraG -
JSU12_RS25375 (97824) 97824..99197 - 1374 WP_001517790.1 conjugal transfer pilus assembly protein TraH -
JSU12_RS25380 (99197) 99197..99577 - 381 WP_001389370.1 F-type conjugal transfer protein TrbF -
JSU12_RS25385 (99564) 99564..99905 - 342 WP_001443031.1 P-type conjugative transfer protein TrbJ -
JSU12_RS25390 (99835) 99835..100380 - 546 WP_000059851.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
JSU12_RS25395 (100367) 100367..100651 - 285 WP_000624109.1 type-F conjugative transfer system pilin chaperone TraQ -
JSU12_RS25400 (100732) 100732..101046 + 315 WP_001324103.1 hypothetical protein -
JSU12_RS25405 (101048) 101048..101395 - 348 WP_001287893.1 conjugal transfer protein TrbA -
JSU12_RS25410 (101411) 101411..102154 - 744 WP_175101081.1 type-F conjugative transfer system pilin assembly protein TraF -
JSU12_RS25415 (102147) 102147..102404 - 258 WP_000864318.1 conjugal transfer protein TrbE -
JSU12_RS25420 (102431) 102431..104239 - 1809 WP_175101080.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
JSU12_RS25425 (104236) 104236..104874 - 639 WP_021518374.1 type-F conjugative transfer system pilin assembly protein TrbC -
JSU12_RS25430 (104883) 104883..105875 - 993 WP_000830183.1 conjugal transfer pilus assembly protein TraU -
JSU12_RS25435 (105872) 105872..106504 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
JSU12_RS25440 (106501) 106501..106887 - 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
JSU12_RS25445 (106884) 106884..109511 - 2628 WP_001064245.1 type IV secretion system protein TraC -
JSU12_RS25450 (109671) 109671..109892 - 222 WP_001278689.1 conjugal transfer protein TraR -
JSU12_RS25455 (110027) 110027..110542 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
JSU12_RS25460 (110539) 110539..110790 - 252 WP_001038342.1 conjugal transfer protein TrbG -
JSU12_RS25465 (110802) 110802..110999 - 198 WP_001324648.1 conjugal transfer protein TrbD -
JSU12_RS25470 (110986) 110986..111576 - 591 WP_001376242.1 conjugal transfer pilus-stabilizing protein TraP -
JSU12_RS25475 (111566) 111566..112993 - 1428 WP_208207901.1 F-type conjugal transfer pilus assembly protein TraB -
JSU12_RS25480 (112993) 112993..113721 - 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
JSU12_RS25485 (113708) 113708..114274 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
JSU12_RS25490 (114296) 114296..114607 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
JSU12_RS25495 (114622) 114622..114987 - 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
JSU12_RS25500 (115020) 115020..115202 - 183 WP_001299736.1 TraY domain-containing protein -
JSU12_RS25505 (115232) 115232..116440 - 1209 WP_001352368.1 IS4 family transposase IS10R Transposase
JSU12_RS25510 (116544) 116544..116717 - 174 WP_230133086.1 TraY domain-containing protein -
JSU12_RS25515 (116852) 116852..117541 - 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
JSU12_RS25520 (117728) 117728..118111 - 384 WP_001151524.1 conjugal transfer relaxosome DNA-binding protein TraM -
JSU12_RS25525 (118443) 118443..119033 + 591 WP_001376243.1 hypothetical protein VF
JSU12_RS25530 (119330) 119330..120151 - 822 WP_001234426.1 DUF932 domain-containing protein -
JSU12_RS25535 (120269) 120269..120556 - 288 WP_000107535.1 hypothetical protein -
JSU12_RS26845 (120581) 120581..120787 - 207 WP_000547968.1 hypothetical protein -
JSU12_RS26850 (120857) 120857..121029 + 173 Protein_133 hypothetical protein -
JSU12_RS26855 (121027) 121027..121257 - 231 WP_071586998.1 hypothetical protein -
JSU12_RS25540 (121477) 121477..121602 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
JSU12_RS26860 (121544) 121544..121693 - 150 Protein_136 plasmid maintenance protein Mok -
- (121679) 121679..121903 - 225 NuclAT_0 - Antitoxin Detail
- (121679) 121679..121903 - 225 NuclAT_0 - Antitoxin Detail
- (121679) 121679..121903 - 225 NuclAT_0 - Antitoxin Detail
- (121679) 121679..121903 - 225 NuclAT_0 - Antitoxin Detail
JSU12_RS25545 (121715) 121715..121903 + 189 WP_001299721.1 hypothetical protein -
JSU12_RS25550 (121872) 121872..122634 - 763 Protein_138 plasmid SOS inhibition protein A -
JSU12_RS25555 (122631) 122631..123065 - 435 WP_000845936.1 conjugation system SOS inhibitor PsiB -
JSU12_RS25560 (123120) 123120..123317 - 198 Protein_140 hypothetical protein -
JSU12_RS25565 (123345) 123345..123578 - 234 WP_000005987.1 DUF905 family protein -
JSU12_RS25570 (123646) 123646..124185 - 540 WP_000290840.1 single-stranded DNA-binding protein -
JSU12_RS25575 (124211) 124211..124417 - 207 WP_000275856.1 hypothetical protein -
JSU12_RS26865 (124487) 124487..124567 + 81 Protein_144 hypothetical protein -
JSU12_RS26870 (124750) 124750..124919 - 170 Protein_145 hypothetical protein -
JSU12_RS25580 (125556) 125556..126527 - 972 WP_000817028.1 ParB/RepB/Spo0J family plasmid partition protein -
JSU12_RS25585 (126527) 126527..127693 - 1167 WP_001238646.1 Sporulation initiation inhibitor protein Soj VF
JSU12_RS25595 (129175) 129175..131376 - 2202 WP_000973520.1 Ferric aerobactin receptor VF
JSU12_RS25600 (131402) 131402..132735 - 1334 Protein_150 L-lysine N6-monooxygenase VF
JSU12_RS25605 (132732) 132732..134474 - 1743 WP_001015721.1 Aerobactin synthase VF
JSU12_RS25610 (134474) 134474..135421 - 948 WP_000011910.1 N(6)-hydroxylysine O-acetyltransferase VF
JSU12_RS25615 (135422) 135422..137146 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
JSU12_RS25620 (137282) 137282..138475 + 1194 WP_000095526.1 MFS transporter -
JSU12_RS25625 (138855) 138855..139235 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
JSU12_RS25630 (139576) 139576..139989 - 414 Protein_156 phosphopyruvate hydratase -
JSU12_RS25635 (139987) 139987..140244 + 258 Protein_157 Tn3 family transposase -
JSU12_RS25640 (140478) 140478..141335 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
JSU12_RS25645 (141332) 141332..142189 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
JSU12_RS25650 (142186) 142186..143013 - 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
JSU12_RS25655 (143013) 143013..143927 - 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
JSU12_RS25660 (144283) 144283..144980 + 698 WP_223155668.1 IS1 family transposase IS1S Transposase
JSU12_RS25665 (145160) 145160..145673 - 514 Protein_163 DUF4113 domain-containing protein -
JSU12_RS25670 (145734) 145734..145838 - 105 Protein_164 AAA family ATPase -
JSU12_RS25675 (145840) 145840..146163 - 324 Protein_165 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance