MGE detailed information
MGE type: Conjugative plasmid MGE length: 130221 bp
Accession: NZ_CP067344 Location: 1..130221 Organism: Escherichia coli strain ECJXMCRH7 Replicon: plasmid pTBH7P2
Accession: NZ_CP067344 Location: 1..130221 Organism: Escherichia coli strain ECJXMCRH7 Replicon: plasmid pTBH7P2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JJB06_RS24160 (1) | 1..858 | + | 858 | WP_168728579.1 | incFII family plasmid replication initiator RepA | - |
| JJB06_RS24165 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JJB06_RS24170 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JJB06_RS24175 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JJB06_RS24180 (3383) | 3383..4080 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| JJB06_RS24185 (4187) | 4187..4621 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| JJB06_RS24190 (4693) | 4693..5043 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| JJB06_RS24195 (5057) | 5057..5332 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| JJB06_RS24200 (5368) | 5368..5790 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| JJB06_RS24205 (5842) | 5842..7536 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| JJB06_RS24210 (7554) | 7554..7916 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| JJB06_RS24215 (7913) | 7913..8149 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| JJB06_RS24220 (8185) | 8185..8853 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| JJB06_RS24225 (8928) | 8928..10178 | + | 1251 | Protein_14 | transposase | - |
| JJB06_RS24230 (10243) | 10243..10947 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| JJB06_RS24235 (11137) | 11137..11952 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| JJB06_RS24240 (12103) | 12103..12807 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| JJB06_RS24245 (12879) | 12879..13616 | + | 738 | WP_001366550.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| JJB06_RS24250 (13613) | 13613..13837 | + | 225 | WP_000743213.1 | hypothetical protein | - |
| JJB06_RS24255 (14048) | 14048..15541 | + | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| JJB06_RS25120 (15572) | 15572..16456 | + | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| JJB06_RS24265 (16673) | 16673..17887 | + | 1215 | WP_000214121.1 | Bicyclomycin resistance protein | ARG |
| JJB06_RS24270 (17915) | 17915..18220 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| JJB06_RS24275 (18332) | 18332..18520 | + | 189 | Protein_24 | IS91 family transposase | - |
| JJB06_RS24280 (18487) | 18487..19389 | - | 903 | Protein_25 | TCR/Tet family MFS transporter | - |
| JJB06_RS24285 (19536) | 19536..20396 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| JJB06_RS24290 (20579) | 20579..20971 | - | 393 | Protein_27 | Tn3 family transposase TnpR_Tn3 | Transposase |
| JJB06_RS24295 (21035) | 21035..21739 | + | 705 | WP_001067858.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| JJB06_RS24300 (21868) | 21868..22632 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| JJB06_RS24305 (23125) | 23125..23709 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| JJB06_RS24310 (23709) | 23709..24947 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| JJB06_RS24315 (24944) | 24944..25858 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| JJB06_RS24320 (25980) | 25980..26684 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| JJB06_RS24325 (26748) | 26748..27017 | - | 270 | Protein_34 | recombinase family protein | - |
| JJB06_RS24330 (27143) | 27143..27493 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| JJB06_RS24335 (27696) | 27696..28709 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| JJB06_RS24340 (28854) | 28854..29351 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| JJB06_RS24345 (29463) | 29463..29753 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| JJB06_RS24350 (29759) | 29759..30597 | + | 839 | Protein_39 | Streptomycin 3''-adenylyltransferase | ARG |
| JJB06_RS24355 (30714) | 30714..31061 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| JJB06_RS24360 (31055) | 31055..31387 | + | 333 | Protein_41 | IS6 family transposase IS15 | Transposase |
| JJB06_RS24365 (31444) | 31444..32148 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| JJB06_RS24370 (32483) | 32483..32875 | + | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| JJB06_RS24375 (33195) | 33195..33581 | - | 387 | WP_063102497.1 | bleomycin binding protein | - |
| JJB06_RS24380 (33775) | 33775..34478 | - | 704 | Protein_45 | IS6 family transposase IS26 | Transposase |
| JJB06_RS24385 (34546) | 34546..35844 | + | 1299 | Protein_46 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JJB06_RS24390 (35878) | 35878..36594 | + | 717 | Protein_47 | Tn3 family transposase | - |
| JJB06_RS24400 (36704) | 36704..36982 | + | 279 | WP_097309154.1 | type II toxin-antitoxin system toxin YacB | - |
| JJB06_RS24405 (37028) | 37028..37876 | + | 849 | WP_023154360.1 | 3'-5' exonuclease | - |
| JJB06_RS24410 (37993) | 37993..38475 | + | 483 | WP_001311056.1 | hypothetical protein | - |
| JJB06_RS24415 (38777) | 38777..39124 | + | 348 | WP_000142450.1 | DUF6404 family protein | - |
| JJB06_RS24420 (39142) | 39142..39327 | - | 186 | Protein_52 | hypothetical protein | - |
| JJB06_RS24425 (39553) | 39553..43368 | + | 3816 | WP_225894552.1 | hypothetical protein | - |
| JJB06_RS24430 (43900) | 43900..44250 | + | 351 | WP_000493379.1 | hypothetical protein | - |
| JJB06_RS24435 (44294) | 44294..44983 | + | 690 | WP_000796228.1 | hypothetical protein | - |
| JJB06_RS24440 (44980) | 44980..45771 | + | 792 | WP_000016493.1 | site-specific integrase | - |
| JJB06_RS24445 (45949) | 45949..46302 | + | 354 | WP_000864812.1 | colicin M immunity protein | - |
| JJB06_RS24450 (46352) | 46352..47167 | - | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| JJB06_RS24455 (47411) | 47411..47938 | + | 528 | WP_000203272.1 | colicin B immunity protein | - |
| JJB06_RS24460 (47956) | 47956..48123 | - | 168 | Protein_60 | colicin-B | - |
| JJB06_RS24465 (48296) | 48296..48499 | + | 204 | Protein_61 | hypothetical protein | - |
| JJB06_RS24470 (49041) | 49041..49277 | + | 237 | WP_014640552.1 | colicin V immunity protein | - |
| JJB06_RS24475 (49255) | 49255..49452 | + | 198 | Protein_63 | colicin V | - |
| JJB06_RS24485 (50401) | 50401..52578 | + | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| JJB06_RS24490 (52623) | 52623..53579 | - | 957 | WP_064055648.1 | Ferri-bacillibactin esterase BesA | VF |
| JJB06_RS24495 (53664) | 53664..54893 | - | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| JJB06_RS24500 (54997) | 54997..58656 | - | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| JJB06_RS24505 (58796) | 58796..59911 | - | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| JJB06_RS24510 (61222) | 61222..62251 | - | 1030 | Protein_70 | integrase core domain-containing protein | - |
| JJB06_RS24515 (62805) | 62805..63004 | + | 200 | Protein_71 | lysis protein | - |
| JJB06_RS24520 (63062) | 63062..63355 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| JJB06_RS24525 (63982) | 63982..65218 | + | 1237 | Protein_73 | IS3 family transposase IS2 | Transposase |
| JJB06_RS24530 (66441) | 66441..67634 | + | 1194 | WP_000450494.1 | GTP-binding protein | - |
| JJB06_RS24535 (67812) | 67812..67961 | + | 150 | Protein_75 | IS3 family transposase IS2 | Transposase |
| JJB06_RS24540 (68271) | 68271..69660 | + | 1390 | Protein_76 | ISNCY family transposase ISKpn21 | Transposase |
| JJB06_RS24550 (70492) | 70492..70760 | + | 269 | Protein_78 | IS3 family transposase ISLad1 | Transposase |
| JJB06_RS24555 (70908) | 70908..71387 | - | 480 | Protein_79 | IS3 family transposase IS629 | Transposase |
| JJB06_RS24560 (71471) | 71471..72979 | - | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| JJB06_RS24565 (73652) | 73652..74391 | - | 740 | Protein_81 | IS3 family transposase IS629 | Transposase |
| JJB06_RS24570 (74530) | 74530..74709 | + | 180 | Protein_82 | transposase | - |
| JJB06_RS24575 (76006) | 76006..76959 | + | 954 | WP_000280980.1 | Protease 7 | VF |
| JJB06_RS24580 (77392) | 77392..78501 | + | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| JJB06_RS24585 (78570) | 78570..79472 | + | 903 | WP_001312822.1 | hypothetical protein | VF |
| JJB06_RS24590 (79846) | 79846..80034 | + | 189 | WP_065203495.1 | serine/threonine protein kinase | - |
| JJB06_RS24595 (80155) | 80155..80895 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| JJB06_RS24600 (81180) | 81180..82157 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| JJB06_RS24605 (82903) | 82903..83226 | + | 324 | Protein_89 | IS21 family transposase IS21 | Transposase |
| JJB06_RS24610 (83228) | 83228..83332 | + | 105 | Protein_90 | AAA family ATPase | - |
| JJB06_RS24615 (83393) | 83393..83906 | + | 514 | Protein_91 | DUF4113 domain-containing protein | - |
| JJB06_RS24625 (85139) | 85139..86053 | + | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| JJB06_RS24630 (86053) | 86053..86880 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| JJB06_RS24635 (86877) | 86877..87734 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| JJB06_RS24640 (87731) | 87731..88588 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| JJB06_RS24645 (88822) | 88822..89079 | - | 258 | Protein_97 | transposase | - |
| JJB06_RS24650 (89077) | 89077..89490 | + | 414 | Protein_98 | phosphopyruvate hydratase | - |
| JJB06_RS24655 (89831) | 89831..90211 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| JJB06_RS24660 (90591) | 90591..91784 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| JJB06_RS24665 (91920) | 91920..93644 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| JJB06_RS24670 (93645) | 93645..94592 | + | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| JJB06_RS24675 (94592) | 94592..96334 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| JJB06_RS24680 (96331) | 96331..97664 | + | 1334 | Protein_104 | L-lysine N6-monooxygenase | VF |
| JJB06_RS24685 (97690) | 97690..99891 | + | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| JJB06_RS24690 (100376) | 100376..101098 | + | 723 | Protein_106 | IS1 family transposase IS1S | Transposase |
| JJB06_RS24695 (101376) | 101376..102542 | + | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| JJB06_RS24700 (102542) | 102542..103513 | + | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JJB06_RS25125 (104150) | 104150..104319 | + | 170 | Protein_109 | hypothetical protein | - |
| JJB06_RS25130 (104502) | 104502..104582 | - | 81 | Protein_110 | hypothetical protein | - |
| JJB06_RS24705 (104652) | 104652..104858 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| JJB06_RS24710 (104884) | 104884..105423 | + | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| JJB06_RS24715 (105491) | 105491..105724 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| JJB06_RS24720 (105752) | 105752..105949 | + | 198 | Protein_114 | hypothetical protein | - |
| JJB06_RS24725 (106004) | 106004..106438 | + | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| JJB06_RS24730 (106435) | 106435..107197 | + | 763 | Protein_116 | plasmid SOS inhibition protein A | - |
| JJB06_RS24735 (107166) | 107166..107354 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (107166) | 107166..107390 | + | 225 | NuclAT_0 | - | - |
| - (107166) | 107166..107390 | + | 225 | NuclAT_0 | - | - |
| - (107166) | 107166..107390 | + | 225 | NuclAT_0 | - | - |
| - (107166) | 107166..107390 | + | 225 | NuclAT_0 | - | - |
| JJB06_RS25135 (107376) | 107376..107525 | + | 150 | Protein_118 | plasmid maintenance protein Mok | - |
| JJB06_RS24740 (107476) | 107476..107592 | + | 117 | WP_001323520.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| JJB06_RS24745 (107812) | 107812..108042 | + | 231 | WP_071586998.1 | hypothetical protein | - |
| JJB06_RS25140 (108040) | 108040..108212 | - | 173 | Protein_121 | hypothetical protein | - |
| JJB06_RS25145 (108282) | 108282..108488 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| JJB06_RS24750 (108513) | 108513..108799 | + | 287 | Protein_123 | hypothetical protein | - |
| JJB06_RS24755 (108917) | 108917..109738 | + | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| JJB06_RS24760 (110035) | 110035..110637 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| JJB06_RS24765 (110958) | 110958..111341 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| JJB06_RS24770 (111528) | 111528..112217 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| JJB06_RS24775 (112310) | 112310..112711 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| JJB06_RS24780 (112744) | 112744..113109 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| JJB06_RS24785 (113124) | 113124..113435 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| JJB06_RS24790 (113457) | 113457..114023 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| JJB06_RS24795 (114010) | 114010..114738 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| JJB06_RS24800 (114738) | 114738..116165 | + | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| JJB06_RS24805 (116155) | 116155..116745 | + | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| JJB06_RS24810 (116732) | 116732..116929 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| JJB06_RS24815 (116941) | 116941..117192 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| JJB06_RS24820 (117189) | 117189..117704 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| JJB06_RS24825 (117839) | 117839..118060 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| JJB06_RS24830 (118349) | 118349..119395 | + | 1047 | Protein_139 | type IV secretion system DNA-binding domain-containing protein | - |
| JJB06_RS24835 (119404) | 119404..119802 | - | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JJB06_RS24840 (119802) | 119802..120029 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| JJB06_RS24845 (120111) | 120111..125381 | + | 5271 | WP_000986963.1 | Multifunctional conjugation protein TraI | Relaxase |
| JJB06_RS24850 (125401) | 125401..126147 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| JJB06_RS24855 (126206) | 126206..127066 | + | 861 | WP_000704513.1 | putative protein YcjY | VF |
| JJB06_RS24860 (127169) | 127169..127729 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| JJB06_RS24865 (127865) | 127865..128077 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| JJB06_RS24870 (128323) | 128323..128397 | + | 75 | Protein_147 | endonuclease | - |
| - (128653) | 128653..128714 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (128653) | 128653..128714 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (128653) | 128653..128714 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (128653) | 128653..128714 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| JJB06_RS24875 (128758) | 128758..128907 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| JJB06_RS24880 (129191) | 129191..129448 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| JJB06_RS25150 (129465) | 129465..129716 | - | 252 | WP_223195197.1 | replication protein RepA | - |
| JJB06_RS25155 (129707) | 129707..129754 | + | 48 | WP_229471593.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|