NZ_CP0672511..133432

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 133432 bp
Accession: NZ_CP067251        Location: 1..133432         Organism: Escherichia coli strain ESBL_DR28       Replicon: plasmid pESBL_DR28a


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJB16_RS22865 (1) 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
JJB16_RS22870 (1263) 1263..2003 - 741 WP_001066953.1 tyrosine-type recombinase/integrase -
JJB16_RS22875 (2183) 2183..2887 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
JJB16_RS22880 (2977) 2977..3042 - 66 Protein_3 EAL domain-containing protein -
JJB16_RS22885 (3086) 3086..3391 - 306 WP_000130000.1 hypothetical protein Relaxase
JJB16_RS22890 (3402) 3402..4607 - 1206 WP_000184001.1 chromate efflux transporter -
JJB16_RS22895 (4763) 4763..4966 - 204 WP_000376616.1 hypothetical protein -
JJB16_RS22900 (5094) 5094..5933 - 840 WP_000259031.1 Dihydropteroate synthase ARG
JJB16_RS22905 (5927) 5927..6274 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
JJB16_RS22910 (6480) 6480..7268 - 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
JJB16_RS22915 (7399) 7399..7872 - 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
JJB16_RS22920 (8030) 8030..9043 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
JJB16_RS22925 (9246) 9246..9596 + 351 WP_000454193.1 DUF3330 domain-containing protein -
JJB16_RS22930 (9773) 9773..10477 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
JJB16_RS22935 (10543) 10543..11226 + 684 Protein_14 IS6 family transposase IS6100 Transposase
JJB16_RS22940 (11719) 11719..12303 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
JJB16_RS22945 (12303) 12303..13541 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
JJB16_RS22950 (13538) 13538..14443 - 906 WP_000219391.1 hypothetical protein ARG
JJB16_RS22955 (14565) 14565..15269 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JJB16_RS22960 (15404) 15404..15499 + 96 WP_013362819.1 23S rRNA methyltransferase attenuation leader peptide -
JJB16_RS22965 (15625) 15625..16362 + 738 WP_013362818.1 rRNA adenine N-6-methyltransferase ARG
JJB16_RS22975 (16992) 16992..17441 + 450 WP_013362817.1 hypothetical protein -
JJB16_RS22980 (17402) 17402..17743 + 342 WP_023909256.1 60 kDa chaperonin 2 VF
JJB16_RS22985 (18018) 18018..19502 + 1485 WP_032152108.1 IS91 family transposase ISVsa3 Transposase
JJB16_RS22990 (19805) 19805..20509 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
JJB16_RS22995 (20546) 20546..21673 - 1128 WP_014837927.1 DUF3883 domain-containing protein -
JJB16_RS23000 (21724) 21724..21951 - 228 WP_000248278.1 hypothetical protein -
JJB16_RS23005 (21975) 21975..22166 + 192 WP_000951934.1 hypothetical protein -
JJB16_RS23010 (22648) 22648..23190 - 543 WP_000587837.1 AAA family ATPase -
JJB16_RS23015 (23203) 23203..24063 - 861 WP_000557454.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
JJB16_RS23020 (24206) 24206..24412 + 207 Protein_30 IS4 family transposase -
JJB16_RS23025 (24476) 24476..25180 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
JJB16_RS23030 (25235) 25235..25612 - 378 Protein_32 Tn3 family transposase TnpR_Tn3 Transposase
JJB16_RS23035 (25848) 25848..26552 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JJB16_RS23040 (26618) 26618..27136 + 519 WP_014839979.1 FidL-like protein -
JJB16_RS23045 (27141) 27141..27557 - 417 WP_014839980.1 Glutathione transferase FosA ARG
JJB16_RS23050 (27943) 27943..28647 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JJB16_RS23055 (28700) 28700..29176 + 477 Protein_37 PAS domain-containing protein -
JJB16_RS23060 (29244) 29244..30341 - 1098 Protein_38 TonB-dependent receptor -
JJB16_RS23065 (30398) 30398..31366 - 969 WP_000654812.1 IS5 family transposase IS903B Transposase
JJB16_RS23070 (31401) 31401..32276 - 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
JJB16_RS23075 (32526) 32526..32717 - 192 Protein_41 IS1380 family transposase -
JJB16_RS23080 (32787) 32787..33491 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JJB16_RS23085 (33557) 33557..34102 + 546 Protein_43 Tn3 family transposase TnpA_Tn3 Transposase
JJB16_RS23090 (34138) 34138..34553 - 416 Protein_44 IS1-like element IS1B family transposase -
JJB16_RS23095 (34802) 34802..35203 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
JJB16_RS23100 (35136) 35136..35393 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
JJB16_RS23105 (35486) 35486..36139 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
JJB16_RS23110 (37078) 37078..37935 - 858 WP_032152935.1 incFII family plasmid replication initiator RepA -
JJB16_RS23115 (37928) 37928..38002 - 75 WP_001365705.1 RepA leader peptide Tap -
JJB16_RS23120 (38237) 38237..38494 - 258 WP_000083821.1 replication regulatory protein RepA -
JJB16_RS23125 (38899) 38899..39921 + 1023 WP_000156883.1 IS110 family transposase ISSm1 Transposase
JJB16_RS23130 (40393) 40393..40746 + 354 WP_000005489.1 hypothetical protein -
JJB16_RS23135 (41159) 41159..41737 - 579 WP_032152936.1 DUF2726 domain-containing protein -
JJB16_RS23140 (41770) 41770..42467 + 698 WP_223230354.1 IS1 family transposase IS1G Transposase
JJB16_RS23145 (42582) 42582..42938 + 357 WP_000229735.1 transposase -
JJB16_RS23150 (42935) 42935..43285 + 351 WP_000624725.1 IS66 family transposase ISEc47 Transposase
JJB16_RS23155 (43316) 43316..43537 + 222 WP_000080227.1 hypothetical protein -
JJB16_RS23160 (43489) 43489..43830 + 342 Protein_58 transposase -
JJB16_RS23165 (43894) 43894..44373 - 480 WP_001496175.1 ArgR family transcriptional regulator -
JJB16_RS23170 (44454) 44454..45857 - 1404 WP_000514417.1 YfcC family protein -
JJB16_RS23175 (45905) 45905..46909 - 1005 WP_000154545.1 Ornithine carbamoyltransferase VF
JJB16_RS23180 (46994) 46994..47905 - 912 WP_000440183.1 carbamate kinase -
JJB16_RS23185 (47916) 47916..49136 - 1221 WP_000410951.1 arginine deiminase -
JJB16_RS23190 (49843) 49843..50457 + 615 Protein_64 VENN motif pre-toxin domain-containing protein -
JJB16_RS23195 (50457) 50457..50903 - 447 Protein_65 plasmid replication initiator RepA -
JJB16_RS23200 (50896) 50896..50970 - 75 WP_032336874.1 RepA leader peptide Tap -
JJB16_RS23205 (51206) 51206..51463 - 258 WP_000083833.1 replication regulatory protein RepA -
JJB16_RS23210 (51747) 51747..51896 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (51940) 51940..52001 + 62 NuclAT_2 - Antitoxin Detail
- (51940) 51940..52001 + 62 NuclAT_2 - Antitoxin Detail
- (51940) 51940..52001 + 62 NuclAT_2 - Antitoxin Detail
- (51940) 51940..52001 + 62 NuclAT_2 - Antitoxin Detail
JJB16_RS23215 (52140) 52140..52322 - 183 WP_000968309.1 hypothetical protein -
JJB16_RS23220 (52423) 52423..53039 + 617 Protein_70 IS1 family transposase IS1G Transposase
JJB16_RS23225 (53077) 53077..54648 - 1572 WP_023149734.1 IS66 family transposase ISCro1 Transposase
JJB16_RS23230 (54668) 54668..55015 - 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
JJB16_RS23235 (55015) 55015..55692 - 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
JJB16_RS23240 (55747) 55747..55836 + 90 Protein_74 IS1 family transposase -
JJB16_RS23245 (56137) 56137..56349 - 213 WP_005012601.1 hypothetical protein -
JJB16_RS23250 (56483) 56483..57043 - 561 WP_000139363.1 fertility inhibition protein FinO -
JJB16_RS23255 (57098) 57098..57844 - 747 WP_023149624.1 conjugal transfer pilus acetylase TraX -
JJB16_RS23260 (57864) 57864..62984 - 5121 WP_013362805.1 Multifunctional conjugation protein TraI Relaxase
JJB16_RS23265 (62984) 62984..65182 - 2199 WP_046464200.1 type IV conjugative transfer system coupling protein TraD -
JJB16_RS23270 (65434) 65434..66165 - 732 WP_000850424.1 conjugal transfer complement resistance protein TraT -
JJB16_RS23275 (66179) 66179..66688 - 510 WP_000628100.1 conjugal transfer entry exclusion protein TraS -
JJB16_RS23280 (66685) 66685..69510 - 2826 WP_001553826.1 conjugal transfer mating-pair stabilization protein TraG -
JJB16_RS23285 (69507) 69507..70880 - 1374 WP_021518370.1 conjugal transfer pilus assembly protein TraH -
JJB16_RS23290 (70867) 70867..71259 - 393 WP_000164675.1 F-type conjugal transfer protein TrbF -
JJB16_RS23295 (71213) 71213..71527 - 315 WP_023149603.1 P-type conjugative transfer protein TrbJ -
JJB16_RS23300 (71517) 71517..72071 - 555 WP_001553830.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
JJB16_RS23305 (72058) 72058..72342 - 285 WP_000624105.1 type-F conjugative transfer system pilin chaperone TraQ -
JJB16_RS23310 (72423) 72423..72758 + 336 WP_000415571.1 hypothetical protein -
JJB16_RS23315 (72739) 72739..73080 - 342 WP_000556794.1 conjugal transfer protein TrbA -
JJB16_RS23320 (73094) 73094..73837 - 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
JJB16_RS23325 (73830) 73830..74087 - 258 WP_000864312.1 conjugal transfer protein TrbE -
JJB16_RS23330 (74114) 74114..75922 - 1809 WP_000821840.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
JJB16_RS23335 (75919) 75919..76557 - 639 WP_021518374.1 type-F conjugative transfer system pilin assembly protein TrbC -
JJB16_RS23340 (76566) 76566..77558 - 993 WP_000830180.1 conjugal transfer pilus assembly protein TraU -
JJB16_RS23345 (77555) 77555..78187 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
JJB16_RS23350 (78184) 78184..78570 - 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
JJB16_RS23355 (78567) 78567..81194 - 2628 WP_001064245.1 type IV secretion system protein TraC -
JJB16_RS23360 (81354) 81354..81575 - 222 WP_001278689.1 conjugal transfer protein TraR -
JJB16_RS23365 (81710) 81710..82225 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
JJB16_RS23370 (82222) 82222..82473 - 252 WP_001038342.1 conjugal transfer protein TrbG -
JJB16_RS23375 (82485) 82485..82682 - 198 WP_001324648.1 conjugal transfer protein TrbD -
JJB16_RS23380 (82669) 82669..83259 - 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
JJB16_RS23385 (83249) 83249..84676 - 1428 WP_000146685.1 F-type conjugal transfer pilus assembly protein TraB -
JJB16_RS23390 (84676) 84676..85404 - 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
JJB16_RS23395 (85391) 85391..85957 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
JJB16_RS23400 (85979) 85979..86290 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
JJB16_RS23405 (86305) 86305..86670 - 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
JJB16_RS23410 (86703) 86703..87104 - 402 WP_001369361.1 conjugal transfer relaxosome DNA-bindin protein TraY -
JJB16_RS23415 (87197) 87197..87886 - 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
JJB16_RS23420 (88073) 88073..88456 - 384 WP_001151524.1 conjugal transfer relaxosome DNA-binding protein TraM -
JJB16_RS23425 (88789) 88789..89379 + 591 WP_285835018.1 hypothetical protein VF
JJB16_RS23430 (89676) 89676..90497 - 822 WP_001234426.1 DUF932 domain-containing protein -
JJB16_RS23435 (90615) 90615..90902 - 288 WP_000107535.1 hypothetical protein -
JJB16_RS24270 (90927) 90927..91133 - 207 WP_000547968.1 hypothetical protein -
JJB16_RS24275 (91203) 91203..91375 + 173 Protein_115 hypothetical protein -
JJB16_RS24280 (91373) 91373..91603 - 231 WP_071886920.1 hypothetical protein -
JJB16_RS23440 (91823) 91823..91948 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
JJB16_RS24285 (91890) 91890..92039 - 150 Protein_118 plasmid maintenance protein Mok -
- (92025) 92025..92056 - 32 NuclAT_1 - Antitoxin Detail
- (92025) 92025..92056 - 32 NuclAT_1 - Antitoxin Detail
- (92025) 92025..92056 - 32 NuclAT_1 - Antitoxin Detail
- (92025) 92025..92056 - 32 NuclAT_1 - Antitoxin Detail
- (93498) 93498..93695 - 198 NuclAT_0 - -
- (93498) 93498..93695 - 198 NuclAT_0 - -
- (93498) 93498..93695 - 198 NuclAT_0 - -
- (93498) 93498..93695 - 198 NuclAT_0 - -
JJB16_RS23450 (93507) 93507..93695 + 189 WP_001299721.1 hypothetical protein -
JJB16_RS23455 (93664) 93664..94426 - 763 Protein_121 plasmid SOS inhibition protein A -
JJB16_RS23460 (94423) 94423..94857 - 435 WP_000845937.1 conjugation system SOS inhibitor PsiB -
JJB16_RS23465 (94912) 94912..95109 - 198 Protein_123 hypothetical protein -
JJB16_RS23470 (95137) 95137..95370 - 234 WP_000005990.1 DUF905 family protein -
JJB16_RS23475 (95438) 95438..95977 - 540 WP_000290840.1 single-stranded DNA-binding protein -
JJB16_RS23480 (96003) 96003..96209 - 207 WP_000275856.1 hypothetical protein -
JJB16_RS24290 (96279) 96279..96451 + 173 Protein_127 hypothetical protein -
JJB16_RS23485 (97180) 97180..98847 + 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
JJB16_RS23490 (99160) 99160..99351 - 192 WP_001027495.1 hypothetical protein -
JJB16_RS23495 (99348) 99348..99770 - 423 WP_000271685.1 DUF1380 family protein -
JJB16_RS23500 (99817) 99817..100242 - 426 WP_001546490.1 antirestriction protein -
JJB16_RS23505 (100656) 100656..101426 - 771 WP_001006251.1 hypothetical protein -
JJB16_RS23510 (101471) 101471..101989 - 519 WP_223349485.1 DUF1380 family protein -
JJB16_RS23515 (101919) 101919..102140 - 222 WP_001104873.1 hypothetical protein -
JJB16_RS23520 (102141) 102141..102824 - 684 WP_032181561.1 DNA methylase -
JJB16_RS23525 (102901) 102901..103212 - 312 WP_012615291.1 hypothetical protein -
JJB16_RS23530 (103209) 103209..104111 - 903 WP_064766247.1 DUF1281 domain-containing protein -
JJB16_RS23535 (104849) 104849..105820 - 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
JJB16_RS23540 (105820) 105820..106986 - 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
JJB16_RS23545 (107574) 107574..108329 - 756 WP_000852146.1 replication initiation protein RepE -
JJB16_RS23550 (109051) 109051..109857 - 807 WP_000016970.1 site-specific integrase -
JJB16_RS23555 (109858) 109858..110163 - 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
JJB16_RS23560 (110165) 110165..110383 - 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
JJB16_RS23565 (110943) 110943..111173 + 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
JJB16_RS23570 (111170) 111170..111586 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
JJB16_RS23575 (111661) 111661..113226 + 1566 WP_001128474.1 AAA family ATPase -
JJB16_RS23580 (113211) 113211..114233 + 1023 WP_000361402.1 helicase UvrD -
JJB16_RS23585 (114487) 114487..115173 - 687 Protein_148 IS1 family transposase IS1S Transposase
JJB16_RS23590 (115699) 115699..117900 - 2202 WP_000973519.1 Ferric aerobactin receptor VF
JJB16_RS23595 (117926) 117926..119259 - 1334 Protein_150 L-lysine N6-monooxygenase VF
JJB16_RS23600 (119256) 119256..120998 - 1743 WP_001015721.1 Aerobactin synthase VF
JJB16_RS23605 (120998) 120998..121945 - 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase VF
JJB16_RS23610 (121946) 121946..123670 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
JJB16_RS23615 (123806) 123806..124999 + 1194 WP_000095526.1 MFS transporter -
JJB16_RS23620 (125379) 125379..125759 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
JJB16_RS23625 (126100) 126100..126513 - 414 Protein_156 phosphopyruvate hydratase -
JJB16_RS23630 (126511) 126511..126768 + 258 Protein_157 Tn3 family transposase -
JJB16_RS23635 (127002) 127002..127859 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
JJB16_RS23640 (127856) 127856..128713 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
JJB16_RS23645 (128710) 128710..129537 - 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
JJB16_RS23650 (129537) 129537..130451 - 915 WP_000949005.1 Putative metal ABC transporter substrate-binding protein Hpf VF
JJB16_RS23655 (130807) 130807..131504 + 698 WP_103215986.1 IS1 family transposase IS1S Transposase
JJB16_RS23660 (131684) 131684..132197 - 514 Protein_163 DUF4113 domain-containing protein -
JJB16_RS23665 (132258) 132258..132362 - 105 Protein_164 AAA family ATPase -
JJB16_RS23670 (132364) 132364..132687 - 324 Protein_165 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance