NZ_CP0642531..167834

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 167834 bp
Accession: NZ_CP064253        Location: 1..167834         Organism: Klebsiella pneumoniae strain JX-CR-hvKP-1       Replicon: plasmid pJX1-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS496_RS27005 () 1074..2048 - 975 WP_011977819.1 ParB/RepB/Spo0J family partition protein -
IS496_RS27010 () 2048..3253 - 1206 WP_011977818.1 AAA family ATPase -
IS496_RS27015 () 4363..5229 - 867 WP_004118283.1 replication initiation protein -
IS496_RS27020 () 5765..5878 + 114 WP_014343462.1 hypothetical protein -
IS496_RS27025 () 6007..6264 + 258 WP_013214010.1 hypothetical protein -
IS496_RS27030 () 6310..7089 - 780 WP_013214009.1 site-specific integrase -
IS496_RS27035 () 7273..8277 - 1005 WP_011977814.1 hypothetical protein -
IS496_RS27040 () 8307..8510 - 204 WP_011977813.1 hypothetical protein -
IS496_RS27045 () 8556..9077 - 522 WP_013214008.1 hypothetical protein -
IS496_RS27050 () 9135..9527 - 393 WP_011977811.1 hypothetical protein -
IS496_RS27055 () 9564..10508 - 945 WP_011977810.1 hypothetical protein -
IS496_RS27060 () 10669..11130 - 462 WP_014343465.1 hypothetical protein -
IS496_RS27065 () 11087..11317 + 231 WP_001261282.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
IS496_RS27070 () 11314..11730 + 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
IS496_RS27075 () 11804..13366 + 1563 WP_004206609.1 AAA family ATPase -
IS496_RS27080 () 13351..14373 + 1023 WP_000361404.1 helicase UvrD -
IS496_RS27085 () 14629..15326 + 698 Protein_17 IS1 family transposase ISKpn14 Transposase
IS496_RS27090 () 15355..15627 + 273 Protein_18 IS5 family transposase ISPan1 Transposase
IS496_RS27095 () 15907..16911 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
IS496_RS27100 () 16990..17424 - 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
IS496_RS27105 () 17496..17846 + 351 WP_001294663.1 mercuric transport protein MerT -
IS496_RS27110 () 17860..18135 + 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
IS496_RS27115 () 18171..18593 + 423 WP_001340589.1 organomercurial transporter MerC -
IS496_RS27120 () 18645..20339 + 1695 WP_000105636.1 mercury(II) reductase -
IS496_RS27125 () 20357..20719 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
IS496_RS27130 () 20716..20952 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
IS496_RS27135 () 20988..21656 + 669 WP_001300294.1 putative signaling protein VF
IS496_RS27140 () 21731..22903 + 1173 Protein_28 transposase -
IS496_RS27145 () 22968..23672 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27150 () 23724..24185 + 462 Protein_30 Tn3 family transposase TnpR_Tn3 Transposase
IS496_RS27155 () 24308..25288 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
IS496_RS27160 () 25564..26445 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
IS496_RS27165 () 26695..27576 - 882 Protein_33 IS1182 family transposase ISKpn6 Transposase
IS496_RS27170 () 27714..28418 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27175 () 28452..33587 - 5136 WP_071177725.1 Multifunctional conjugation protein TraI Relaxase
IS496_RS27180 () 33587..35812 - 2226 WP_000009363.1 type IV conjugative transfer system coupling protein TraD -
IS496_RS27185 () 35863..36600 - 738 WP_015059020.1 hypothetical protein -
IS496_RS27190 () 36803..37534 - 732 WP_021559024.1 complement resistance protein TraT -
IS496_RS27195 () 37559..38080 - 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
IS496_RS27200 () 38113..40929 - 2817 WP_015059018.1 conjugal transfer mating pair stabilization protein TraG -
IS496_RS27205 () 40926..42299 - 1374 WP_000944325.1 conjugal transfer protein TraH -
IS496_RS27210 () 42286..42678 - 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
IS496_RS27215 () 42632..43006 - 375 WP_071776752.1 P-type conjugative transfer protein TrbJ -
IS496_RS27220 () 42936..43481 - 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
IS496_RS27225 () 43468..43749 - 282 WP_000549793.1 type-F conjugative transfer system pilin chaperone TraQ -
IS496_RS27230 () 43865..44614 - 750 WP_072354014.1 type-F conjugative transfer system pilin assembly protein TraF -
IS496_RS27235 () 44601..44858 - 258 WP_053913405.1 conjugal transfer protein TrbE -
IS496_RS27240 () 44885..46735 - 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
IS496_RS27245 () 46732..47154 - 423 WP_001229309.1 HNH endonuclease -
IS496_RS27250 () 47180..47551 - 372 WP_000056336.1 hypothetical protein -
IS496_RS27255 () 47548..48186 - 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
IS496_RS27260 () 48213..48734 - 522 WP_015059014.1 hypothetical protein -
IS496_RS27265 () 48797..49105 - 309 WP_000412447.1 hypothetical protein -
IS496_RS27270 () 49132..50124 - 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
IS496_RS27275 () 50121..50753 - 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
IS496_RS27280 () 50750..51136 - 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
IS496_RS27285 () 51133..53760 - 2628 WP_015059012.1 type IV secretion system protein TraC -
IS496_RS27290 () 53920..54141 - 222 WP_001278692.1 conjugal transfer protein TraR -
IS496_RS27295 () 54276..54791 - 516 WP_062955122.1 type IV conjugative transfer system lipoprotein TraV -
IS496_RS27300 () 54788..55039 - 252 WP_001038341.1 conjugal transfer protein TrbG -
IS496_RS27305 () 55051..55281 - 231 WP_001352845.1 conjugal transfer protein TrbD -
IS496_RS27310 () 55235..55825 - 591 WP_000002778.1 conjugal transfer protein TraP -
IS496_RS27315 () 55815..57242 - 1428 WP_032297072.1 conjugal transfer protein TraB -
IS496_RS27320 () 57242..57946 - 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
IS496_RS27325 () 57957..58523 - 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
IS496_RS27330 () 58545..58856 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
IS496_RS27335 () 58871..59236 - 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
IS496_RS27340 () 59270..59497 - 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
IS496_RS27345 () 59591..60277 - 687 WP_015059009.1 PAS domain-containing protein -
IS496_RS27350 () 60468..60851 - 384 WP_000124981.1 relaxosome protein TraM -
IS496_RS27355 () 61128..61775 + 648 WP_015059008.1 hypothetical protein VF
IS496_RS27360 () 62072..62893 - 822 WP_001234445.1 DUF945 domain-containing protein -
IS496_RS27365 () 63004..63300 - 297 WP_001272251.1 hypothetical protein -
IS496_RS27370 () 63600..63977 + 378 Protein_74 hypothetical protein -
IS496_RS27375 () 64215..64373 - 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 64417..64641 - 225 NuclAT_0 - Antitoxin Detail
- () 64417..64641 - 225 NuclAT_0 - Antitoxin Detail
- () 64417..64641 - 225 NuclAT_0 - Antitoxin Detail
- () 64417..64641 - 225 NuclAT_0 - Antitoxin Detail
IS496_RS27380 () 64653..65372 - 720 WP_001276217.1 plasmid SOS inhibition protein A -
IS496_RS27385 () 65369..65803 - 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
IS496_RS27390 () 65872..67895 - 2024 Protein_78 ParB/RepB/Spo0J family partition protein -
IS496_RS27395 () 67956..68189 - 234 WP_000006003.1 DUF905 family protein -
IS496_RS27400 () 68247..68774 - 528 WP_000290834.1 single-stranded DNA-binding protein -
IS496_RS27405 () 69611..70174 - 564 WP_015059007.1 class I SAM-dependent methyltransferase -
IS496_RS27410 () 70221..71582 - 1362 WP_000170695.1 DUF3560 domain-containing protein -
IS496_RS27415 () 71634..71864 - 231 WP_000218642.1 hypothetical protein -
IS496_RS27420 () 73264..74931 + 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
IS496_RS27425 () 75245..75436 - 192 WP_001027493.1 hypothetical protein -
IS496_RS27430 () 75433..75855 - 423 WP_000271762.1 DUF1380 family protein -
IS496_RS27435 () 75902..76327 - 426 WP_001198928.1 antirestriction protein -
IS496_RS27440 () 76745..77521 - 777 WP_001383963.1 hypothetical protein -
IS496_RS27445 () 77572..78006 - 435 WP_000274503.1 DUF1380 family protein -
IS496_RS27450 () 78020..78241 - 222 WP_001104881.1 hypothetical protein -
IS496_RS27455 () 78242..78925 - 684 WP_000085883.1 DNA methylase -
IS496_RS27460 () 79002..79295 - 294 WP_032146011.1 hypothetical protein -
IS496_RS27465 () 79442..80404 + 963 WP_000959884.1 plasmid segregation protein ParM -
IS496_RS27470 () 80407..80757 + 351 WP_000361389.1 plasmid partitioning/stability family protein -
IS496_RS27475 () 80880..81161 - 282 WP_001333089.1 hypothetical protein -
IS496_RS27480 () 81289..81523 - 235 Protein_96 type II toxin-antitoxin system RelE/ParE family toxin -
IS496_RS27485 () 82972..83112 - 141 WP_071557810.1 hypothetical protein -
IS496_RS27490 () 83103..83807 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
IS496_RS27495 () 83895..84176 + 282 WP_015059004.1 sodium/hydrogen exchanger -
IS496_RS27500 () 84257..85012 - 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
IS496_RS27505 () 85182..86042 - 861 WP_000027057.1 Beta-lactamase TEM ARG
IS496_RS27510 () 86225..86761 - 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
IS496_RS27515 () 86853..87041 + 189 WP_000957857.1 hypothetical protein -
IS496_RS27520 () 87051..87668 + 618 Protein_104 IS91 family transposase ISSbo1 Transposase
IS496_RS27525 () 87719..88423 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27530 () 88809..89225 + 417 WP_014839980.1 Glutathione transferase FosA ARG
IS496_RS27535 () 89230..89748 - 519 WP_014839979.1 hypothetical protein -
IS496_RS27540 () 89814..90518 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27545 () 90974..91564 - 591 Protein_109 IS91 family transposase ISSbo1 Transposase
IS496_RS27550 () 91629..92333 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27555 () 92413..92862 + 450 Protein_111 PAS domain-containing protein -
IS496_RS27560 () 92930..94027 - 1098 Protein_112 TonB-dependent receptor -
IS496_RS27565 () 94084..95052 - 969 WP_013362812.1 IS5 family transposase IS903B Transposase
IS496_RS27570 () 95087..95962 - 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
IS496_RS27575 () 96212..96403 - 192 Protein_115 transposase -
IS496_RS27580 () 96473..97177 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27585 () 97243..97788 + 546 Protein_117 Tn3 family transposase TnpA_Tn3 Transposase
IS496_RS27590 () 97824..98239 - 416 Protein_118 IS1 family transposase -
IS496_RS27595 () 98488..98889 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
IS496_RS27600 () 98822..99079 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
IS496_RS27605 () 99172..99825 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
IS496_RS27610 () 100764..101621 - 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
IS496_RS27615 () 101614..101688 - 75 WP_001375168.1 RepA leader peptide Tap -
IS496_RS27620 () 101933..102181 - 249 WP_000083837.1 replication regulatory protein RepA -
IS496_RS27625 () 102465..102614 - 150 WP_001312851.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 102659..102718 + 60 NuclAT_1 - Antitoxin Detail
- () 102659..102718 + 60 NuclAT_1 - Antitoxin Detail
- () 102659..102718 + 60 NuclAT_1 - Antitoxin Detail
- () 102659..102718 + 60 NuclAT_1 - Antitoxin Detail
IS496_RS27630 () 102919..103149 - 231 WP_001736714.1 hypothetical protein -
IS496_RS27635 () 103313..103912 - 600 WP_032083981.1 hypothetical protein -
IS496_RS27640 () 104298..104498 - 201 WP_015059022.1 hypothetical protein -
IS496_RS27645 () 104630..105190 - 561 WP_000139328.1 fertility inhibition protein FinO -
IS496_RS27650 () 105245..105991 - 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
IS496_RS27655 () 106056..106760 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27660 () 106813..106878 + 66 Protein_132 helix-turn-helix domain-containing protein -
IS496_RS27665 () 106881..109847 + 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
IS496_RS27670 () 109926..110930 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
IS496_RS27675 () 111112..111288 - 177 WP_000954592.1 Arm DNA-binding domain-containing protein -
IS496_RS27680 () 111410..111634 - 225 WP_000743213.1 hypothetical protein -
IS496_RS27685 () 111631..112368 - 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
IS496_RS27690 () 112854..112994 - 141 WP_001044210.1 hypothetical protein -
IS496_RS27695 () 113000..113704 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27700 () 113784..114284 + 501 WP_001239317.1 hypothetical protein -
IS496_RS27705 () 114434..115075 + 642 WP_001011939.1 Chloramphenicol acetyltransferase 2 ARG
IS496_RS27710 () 115208..115912 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27715 () 116381..116938 - 558 WP_042934582.1 hypothetical protein -
IS496_RS27720 () 117066..117443 - 378 Protein_144 restriction endonuclease -
IS496_RS27725 () 117590..118570 - 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
IS496_RS27730 () 118639..119031 + 393 Protein_146 3'-5' exonuclease -
IS496_RS27735 () 119084..119479 + 396 WP_015493087.1 hypothetical protein -
IS496_RS27740 () 119476..120087 + 612 WP_015493086.1 DUF2913 family protein -
IS496_RS27745 () 120084..121034 - 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
IS496_RS27750 () 121181..121381 - 201 WP_040219232.1 hypothetical protein -
IS496_RS27755 () 121435..122067 - 633 WP_022652286.1 Tn3 family transposase TnpR_TnEc1 Transposase
IS496_RS27760 () 122430..123635 + 1206 WP_015493083.1 Plasmid partition protein A VF
IS496_RS27765 () 123632..124603 + 972 WP_016479949.1 ParB/RepB/Spo0J family partition protein -
IS496_RS27770 () 124739..126010 - 1272 WP_015493081.1 Y-family DNA polymerase -
IS496_RS27775 () 126010..126432 - 423 WP_015493080.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
IS496_RS27780 () 126612..127283 - 672 WP_015493079.1 SOS response-associated peptidase family protein -
IS496_RS27785 () 127642..128319 + 678 WP_002211749.1 DNA methylase -
IS496_RS27790 () 128319..128540 + 222 WP_015493077.1 hypothetical protein -
IS496_RS27795 () 128551..128970 + 420 WP_015493076.1 DUF1380 domain-containing protein -
IS496_RS27800 () 129024..129803 + 780 WP_015493075.1 hypothetical protein -
IS496_RS27805 () 130208..130714 + 507 WP_015493074.1 antirestriction protein ArdA -
IS496_RS27810 () 130757..130948 + 192 WP_015493073.1 hypothetical protein -
IS496_RS27815 () 131141..131395 + 255 WP_015493072.1 DNA polymerase III subunit theta -
IS496_RS27820 () 131430..131747 + 318 Protein_164 hypothetical protein -
IS496_RS27825 () 132373..132603 + 231 WP_015493071.1 DUF905 domain-containing protein -
IS496_RS27830 () 132674..134683 + 2010 Protein_166 ParB/RepB/Spo0J family partition protein -
IS496_RS27835 () 134726..135157 + 432 WP_008324186.1 conjugation system SOS inhibitor PsiB -
IS496_RS27840 () 135154..135882 + 729 WP_008324185.1 plasmid SOS inhibition protein A -
IS496_RS27845 () 135879..136202 + 324 WP_008324183.1 hypothetical protein -
IS496_RS27850 () 136264..136623 + 360 WP_015493069.1 hypothetical protein -
IS496_RS27855 () 137249..137623 + 375 WP_008324180.1 hypothetical protein -
IS496_RS27860 () 137749..138453 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS496_RS27865 () 138508..138873 - 366 Protein_173 type IV conjugative transfer system protein TraE -
IS496_RS27870 () 138893..139198 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
IS496_RS27875 () 139212..139580 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
IS496_RS27880 () 139642..139848 - 207 WP_171773970.1 TraY domain-containing protein -
IS496_RS27885 () 139963..140700 - 738 WP_013214018.1 conjugal transfer protein TrbJ -
IS496_RS27890 () 140900..141316 - 417 WP_014343494.1 relaxosome protein TraM -
IS496_RS27895 () 141707..142192 + 486 WP_014343495.1 hypothetical protein VF
IS496_RS27900 () 142225..142554 - 330 WP_013214015.1 hypothetical protein -
IS496_RS27905 () 142587..143408 - 822 WP_004152492.1 DUF945 domain-containing protein -
IS496_RS27910 () 144345..144623 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
IS496_RS27915 () 144613..144933 - 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
IS496_RS27920 () 145014..145238 - 225 WP_014343499.1 hypothetical protein -
IS496_RS27925 () 145249..145461 - 213 WP_014343500.1 hypothetical protein -
IS496_RS27930 () 145522..145878 - 357 WP_014343501.1 hypothetical protein -
IS496_RS27935 () 146719..147036 - 318 WP_014343505.1 hypothetical protein -
IS496_RS27940 () 147051..147401 - 351 WP_040245917.1 hypothetical protein -
IS496_RS27945 () 147398..147670 - 273 WP_040245921.1 hypothetical protein -
IS496_RS27950 () 148363..148521 - 159 WP_014343509.1 type I toxin-antitoxin system Hok family toxin -
IS496_RS27955 () 148749..149123 - 375 WP_014343510.1 hypothetical protein -
IS496_RS27960 () 149179..149505 - 327 WP_013023807.1 hypothetical protein -
IS496_RS27965 () 149502..150230 - 729 WP_001568058.1 plasmid SOS inhibition protein A -
IS496_RS27970 () 150227..150658 - 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
IS496_RS27975 () 150703..152760 - 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
IS496_RS27980 () 152830..153078 - 249 WP_001568055.1 DUF905 domain-containing protein -
IS496_RS27985 () 153127..153669 - 543 WP_014343512.1 single-stranded DNA-binding protein -
IS496_RS27990 () 154499..155062 - 564 WP_014343514.1 methyltransferase -
IS496_RS27995 () 155110..156465 - 1356 WP_014343515.1 DUF3560 domain-containing protein -
IS496_RS28000 () 156517..156747 - 231 WP_001568051.1 hypothetical protein -
IS496_RS28005 () 156839..157066 - 228 WP_001568050.1 hypothetical protein -
IS496_RS28010 () 157746..158066 - 321 WP_001568049.1 hypothetical protein -
IS496_RS28015 () 158101..158355 - 255 WP_011977779.1 DNA polymerase III subunit theta -
IS496_RS28020 () 158543..158734 - 192 WP_001568047.1 hypothetical protein -
IS496_RS28025 () 158777..159283 - 507 WP_013214014.1 antirestriction protein ArdA -
IS496_RS28030 () 159326..159754 - 429 WP_001568045.1 antirestriction protein -
IS496_RS28035 () 160435..161202 - 768 WP_013214013.1 hypothetical protein -
IS496_RS28040 () 161256..161675 - 420 WP_001568043.1 DUF1380 domain-containing protein -
IS496_RS28045 () 161685..161906 - 222 WP_001568042.1 hypothetical protein -
IS496_RS28050 () 161906..162607 - 702 WP_001568041.1 DNA methylase -
IS496_RS28055 () 163044..163274 - 231 WP_001568040.1 hypothetical protein -
IS496_RS28060 () 163337..164008 - 672 WP_013214012.1 plasmid partitioning/stability family protein -
IS496_RS28065 () 164011..164982 - 972 WP_004152353.1 mediator of plasmid stability -
IS496_RS28070 () 165231..166718 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
IS496_RS28075 () 167126..167557 + 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance