MGE detailed information

MGE type: Mobilizable plasmid        MGE length: 165027 bp
Accession: NZ_CP064237        Location: 1..165027         Organism: Klebsiella pneumoniae strain JX-CR-hvKP-4       Replicon: plasmid pJX4-2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS499_RS28160 () 88..324 - 237 Protein_1 DUF3330 domain-containing protein -
IS499_RS28165 () 527..1540 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
IS499_RS28170 () 1720..2274 + 555 WP_032488579.1 aminoglycoside N-acetyltransferase AAC(6')-Ib3 -
IS499_RS28175 () 2541..3800 + 1260 Protein_4 Inner membrane transport protein YdhC ARG
IS499_RS28180 () 3992..4339 + 348 WP_000679427.1 quaternary ammonium compound efflux SMR transporter QacE delta 1 -
IS499_RS28185 () 4333..4542 + 210 Protein_6 dihydropteroate synthase -
IS499_RS28190 () 4731..5777 - 1047 Protein_7 Methyl-accepting chemotaxis protein McpQ VF
IS499_RS28195 () 5963..6925 + 963 Protein_8 IS1380 family transposase ISEcp1 Transposase
IS499_RS28200 () 6981..7949 - 969 WP_013362812.1 IS5 family transposase IS903B Transposase
IS499_RS28205 () 7984..8859 - 876 WP_001617865.1 Beta-lactamase CTX-M-97 ARG
IS499_RS28210 () 9109..9417 - 309 Protein_11 IS1380 family transposase -
IS499_RS28215 () 9451..10419 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
IS499_RS28220 () 10474..11436 - 963 Protein_13 IS1380 family transposase ISEcp1 Transposase
IS499_RS28225 () 11622..12668 + 1047 Protein_14 Methyl-accepting chemotaxis protein McpQ VF
IS499_RS28230 () 12857..13066 - 210 Protein_15 dihydropteroate synthase -
IS499_RS28235 () 13060..13407 - 348 WP_000679427.1 quaternary ammonium compound efflux SMR transporter QacE delta 1 -
IS499_RS28240 () 13599..14858 - 1260 Protein_17 Inner membrane transport protein YdhC ARG
IS499_RS28245 () 15125..15679 - 555 WP_032488579.1 aminoglycoside N-acetyltransferase AAC(6')-Ib3 -
IS499_RS28250 () 15859..16872 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
IS499_RS28255 () 17075..17311 + 237 Protein_20 DUF3330 domain-containing protein -
IS499_RS28260 () 17375..18079 + 705 WP_001067845.1 IS6 family transposase IS26 Transposase
IS499_RS28265 () 18269..19273 + 1005 WP_021546935.1 IS110 family transposase IS4321R Transposase
IS499_RS28270 () 19917..20201 + 285 WP_001178089.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
IS499_RS28275 () 20201..20476 + 276 WP_000421257.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
IS499_RS28280 () 20526..21223 - 698 Protein_25 IS1 family transposase IS1R Transposase
IS499_RS28285 () 21297..21656 + 360 WP_085452786.1 colicin -
IS499_RS28290 () 21678..22013 - 336 WP_001080730.1 colicin 1A immunity protein -
IS499_RS28295 () 22142..22489 + 348 WP_000142451.1 hypothetical protein -
IS499_RS28300 () 22576..23280 - 705 WP_001067845.1 IS6 family transposase IS26 Transposase
IS499_RS28305 () 23344..23829 + 486 Protein_30 Tn3 family transposase TnpR_Tn3 Transposase
IS499_RS28310 () 23906..25297 + 1392 WP_000085084.1 SIR2 family protein -
IS499_RS28315 () 25294..27366 + 2073 WP_001084041.1 DUF87 domain-containing protein -
IS499_RS28320 () 27556..27795 - 240 WP_000371884.1 hypothetical protein -
IS499_RS28325 () 27963..28640 + 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
IS499_RS28330 () 28640..28987 + 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
IS499_RS28335 () 29007..30578 + 1572 WP_029392005.1 IS66 family transposase ISCro1 Transposase
IS499_RS28340 () 30777..31268 + 492 WP_000528930.1 hypothetical protein -
IS499_RS28345 () 31280..32038 + 759 WP_000494510.1 hypothetical protein -
IS499_RS28350 () 32260..33852 + 1593 WP_001350003.1 hypothetical protein -
IS499_RS28355 () 33887..35011 + 1125 WP_000386705.1 DUF4238 domain-containing protein -
IS499_RS28360 () 35011..35301 + 291 WP_000648897.1 hypothetical protein -
IS499_RS28365 () 35874..36875 + 1002 WP_000785695.1 DUF4238 domain-containing protein -
IS499_RS28370 () 37049..37393 - 345 WP_000792769.1 hypothetical protein -
IS499_RS28375 () 37891..38145 - 255 WP_000678528.1 hypothetical protein -
IS499_RS28380 () 38195..39121 - 927 WP_001290414.1 hypothetical protein -
IS499_RS28385 () 39680..39898 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
IS499_RS28390 () 39900..40205 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
IS499_RS28395 () 40206..40640 + 435 Protein_48 tyrosine-type recombinase/integrase -
IS499_RS28400 () 40705..41409 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS499_RS28405 () 41461..42198 - 738 Protein_50 conjugal transfer protein TraB -
IS499_RS28410 () 42198..42902 - 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
IS499_RS28415 () 42913..43479 - 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
IS499_RS28420 () 43501..43812 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
IS499_RS28425 () 43827..44192 - 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
IS499_RS28430 () 44226..44453 - 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
IS499_RS28435 () 44547..45233 - 687 WP_015059009.1 PAS domain-containing protein -
IS499_RS28440 () 45424..45807 - 384 WP_000124981.1 relaxosome protein TraM -
IS499_RS28445 () 46084..46731 + 648 WP_015059008.1 hypothetical protein VF
IS499_RS28450 () 47028..47849 - 822 WP_001234445.1 DUF945 domain-containing protein -
IS499_RS28455 () 47960..48256 - 297 WP_001272251.1 hypothetical protein -
IS499_RS28460 () 48556..48933 + 378 Protein_61 hypothetical protein -
IS499_RS28465 () 49171..49329 - 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 49373..49597 - 225 NuclAT_0 - -
- () 49373..49597 - 225 NuclAT_0 - -
- () 49373..49597 - 225 NuclAT_0 - -
- () 49373..49597 - 225 NuclAT_0 - -
IS499_RS28470 () 49609..50328 - 720 WP_001276217.1 plasmid SOS inhibition protein A -
IS499_RS28475 () 50325..50759 - 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
IS499_RS28480 () 50828..52851 - 2024 Protein_65 ParB/RepB/Spo0J family partition protein -
IS499_RS28485 () 52912..53145 - 234 WP_000006003.1 DUF905 family protein -
IS499_RS28490 () 53203..53730 - 528 WP_000290834.1 single-stranded DNA-binding protein -
IS499_RS28495 () 54573..55136 - 564 WP_001298559.1 class I SAM-dependent methyltransferase -
IS499_RS28500 () 55183..56544 - 1362 WP_000170695.1 DUF3560 domain-containing protein -
IS499_RS28505 () 56596..56826 - 231 WP_000218642.1 hypothetical protein -
IS499_RS28510 () 58226..59893 + 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
IS499_RS28515 () 60207..60398 - 192 WP_001027495.1 hypothetical protein -
IS499_RS28520 () 60395..60817 - 423 WP_000271762.1 DUF1380 family protein -
IS499_RS28525 () 60864..61289 - 426 WP_089079046.1 antirestriction protein -
IS499_RS28530 () 61703..62473 - 771 WP_001006225.1 hypothetical protein -
IS499_RS28535 () 62518..62952 - 435 WP_021547622.1 DUF1380 family protein -
IS499_RS28540 () 62964..63185 - 222 WP_001104887.1 hypothetical protein -
IS499_RS28545 () 63186..63869 - 684 WP_000086160.1 DNA methylase -
IS499_RS28550 () 63945..64250 - 306 WP_032155763.1 hypothetical protein -
IS499_RS28555 () 64254..65156 - 903 WP_001302618.1 DUF1281 domain-containing protein -
IS499_RS28560 () 65574..65822 + 249 WP_000618110.1 DinI-like family protein -
IS499_RS28565 () 65819..66256 + 438 WP_000109071.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
IS499_RS28570 () 66256..67527 + 1272 WP_000457496.1 Y-family DNA polymerase -
IS499_RS28575 () 67532..67924 - 393 WP_000340829.1 plasmid partitioning/stability family protein -
IS499_RS28580 () 67929..68900 - 972 WP_001103697.1 hypothetical protein -
IS499_RS28585 () 69129..69773 + 645 WP_000633913.1 AAA family ATPase -
IS499_RS28590 () 69767..70042 + 276 WP_000239529.1 hypothetical protein -
IS499_RS28595 () 70234..70660 - 427 Protein_88 tyrosine-type recombinase/integrase -
IS499_RS28600 () 70840..71430 + 591 Protein_89 colicin-B -
IS499_RS28605 () 71446..72143 - 698 Protein_90 IS1 family transposase IS1G Transposase
IS499_RS28610 () 72199..72393 - 195 Protein_91 colicin M immunity protein -
IS499_RS28615 () 72565..72939 - 375 Protein_92 IS91 family transposase ISSod25 Transposase
IS499_RS28620 () 72999..73703 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS499_RS28625 () 73778..74053 + 276 Protein_94 PAS domain-containing protein -
IS499_RS28630 () 74117..74821 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS499_RS28635 () 74875..75198 - 324 Protein_96 class II aldolase/adducin family protein -
IS499_RS28640 () 75191..76443 - 1253 Protein_97 four-carbon acid sugar kinase family protein -
IS499_RS28645 () 76455..77357 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
IS499_RS28650 () 77618..78379 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
IS499_RS28655 () 78400..79260 - 861 WP_002904004.1 Beta-lactamase SHV-2 ARG
IS499_RS28660 () 79397..79465 + 69 Protein_101 IS6 family transposase -
IS499_RS28665 () 79501..82467 - 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
IS499_RS28670 () 82471..83031 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
IS499_RS28675 () 83423..84040 + 618 Protein_104 replication protein -
IS499_RS28680 () 84574..84852 + 279 WP_013213990.1 hypothetical protein -
IS499_RS28685 () 84963..85388 + 426 WP_013213989.1 antirestriction protein -
IS499_RS28690 () 85516..85671 + 156 WP_013213988.1 hypothetical protein -
IS499_RS28695 () 85717..86013 + 297 WP_013213987.1 transcriptional regulator -
IS499_RS28700 () 86117..86998 + 882 Protein_109 IS1182 family transposase ISKpn6 Transposase
IS499_RS28705 () 87248..88129 - 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
IS499_RS28710 () 88405..89385 - 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
IS499_RS28715 () 89508..89969 - 462 Protein_112 Tn3 family transposase TnpR_Tn3 Transposase
IS499_RS28720 () 90021..90725 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS499_RS28725 () 90762..90951 - 190 Protein_114 Tn3 family transposase -
IS499_RS28730 () 91281..92141 - 861 WP_000027057.1 Beta-lactamase TEM ARG
IS499_RS28735 () 92324..92881 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
IS499_RS28740 () 93045..95498 + 2454 Protein_117 Tn3 family transposase TnpA_Tn3 Transposase
IS499_RS28745 () 95563..96267 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS499_RS28750 () 96333..96878 + 546 Protein_119 Tn3 family transposase TnpA_Tn3 Transposase
IS499_RS28755 () 96914..97329 - 416 Protein_120 IS1 family transposase -
IS499_RS28760 () 97578..97979 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
IS499_RS28765 () 97912..98169 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
IS499_RS28770 () 98262..98915 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
IS499_RS28775 () 99854..100711 - 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
IS499_RS28780 () 100704..100778 - 75 WP_001375168.1 RepA leader peptide Tap -
IS499_RS28785 () 101023..101271 - 249 WP_000083837.1 replication regulatory protein RepA -
IS499_RS28790 () 101555..101704 - 150 WP_001312851.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 101749..101808 + 60 NuclAT_1 - -
- () 101749..101808 + 60 NuclAT_1 - -
- () 101749..101808 + 60 NuclAT_1 - -
- () 101749..101808 + 60 NuclAT_1 - -
IS499_RS28795 () 102009..102239 - 231 WP_001736714.1 hypothetical protein -
IS499_RS28800 () 102403..103002 - 600 WP_032083981.1 hypothetical protein -
IS499_RS28805 () 103388..103588 - 201 WP_015059022.1 hypothetical protein -
IS499_RS28810 () 103720..104280 - 561 WP_000139328.1 fertility inhibition protein FinO -
IS499_RS28815 () 104335..105081 - 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
IS499_RS28820 () 105101..105262 - 162 Protein_133 DNA helicase -
IS499_RS28825 () 105326..106030 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
IS499_RS28830 () 106082..106426 + 345 Protein_135 IS6 family transposase IS26 Transposase
IS499_RS28835 () 106481..106846 - 366 Protein_136 type IV conjugative transfer system protein TraE -
IS499_RS28840 () 106866..107171 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
IS499_RS28845 () 107185..107553 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
IS499_RS28850 () 107615..107821 - 207 WP_171773970.1 TraY domain-containing protein -
IS499_RS28855 () 107936..108673 - 738 WP_154244330.1 conjugal transfer protein TrbJ -
IS499_RS28860 () 108873..109289 - 417 WP_014343494.1 relaxosome protein TraM -
IS499_RS28865 () 109680..110165 + 486 WP_014343495.1 hypothetical protein VF
IS499_RS28870 () 110198..110527 - 330 WP_013214015.1 hypothetical protein -
IS499_RS28875 () 110560..111381 - 822 WP_004152492.1 DUF945 domain-containing protein -
IS499_RS28880 () 112318..112596 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
IS499_RS28885 () 112586..112906 - 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
IS499_RS28890 () 112987..113211 - 225 WP_014343499.1 hypothetical protein -
IS499_RS28895 () 113222..113434 - 213 WP_014343500.1 hypothetical protein -
IS499_RS28900 () 113495..113851 - 357 WP_014343501.1 hypothetical protein -
IS499_RS28905 () 114692..115009 - 318 WP_014343505.1 hypothetical protein -
IS499_RS28910 () 115024..115374 - 351 WP_040245917.1 hypothetical protein -
IS499_RS28915 () 115371..115643 - 273 WP_040245921.1 hypothetical protein -
IS499_RS28920 () 116336..116494 - 159 WP_014343509.1 type I toxin-antitoxin system Hok family toxin -
IS499_RS28925 () 116722..117096 - 375 WP_014343510.1 hypothetical protein -
IS499_RS28930 () 117152..117478 - 327 WP_013023807.1 hypothetical protein -
IS499_RS28935 () 117475..118203 - 729 WP_001568058.1 plasmid SOS inhibition protein A -
IS499_RS28940 () 118200..118631 - 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
IS499_RS28945 () 118676..120733 - 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
IS499_RS28950 () 120803..121051 - 249 WP_001568055.1 DUF905 domain-containing protein -
IS499_RS28955 () 121100..121642 - 543 WP_014343512.1 single-stranded DNA-binding protein -
IS499_RS28960 () 122475..123038 - 564 WP_014343514.1 methyltransferase -
IS499_RS28965 () 123086..124441 - 1356 WP_014343515.1 DUF3560 domain-containing protein -
IS499_RS28970 () 124493..124723 - 231 WP_001568051.1 hypothetical protein -
IS499_RS28975 () 124815..125042 - 228 WP_001568050.1 hypothetical protein -
IS499_RS28980 () 125722..126042 - 321 WP_001568049.1 hypothetical protein -
IS499_RS28985 () 126077..126331 - 255 WP_011977779.1 DNA polymerase III subunit theta -
IS499_RS28990 () 126519..126710 - 192 WP_001568047.1 hypothetical protein -
IS499_RS28995 () 126753..127259 - 507 WP_013214014.1 antirestriction protein ArdA -
IS499_RS29000 () 127302..127730 - 429 WP_001568045.1 antirestriction protein -
IS499_RS29005 () 128411..129178 - 768 WP_013214013.1 hypothetical protein -
IS499_RS29010 () 129232..129651 - 420 WP_001568043.1 DUF1380 domain-containing protein -
IS499_RS29015 () 129661..129882 - 222 WP_001568042.1 hypothetical protein -
IS499_RS29020 () 129882..130583 - 702 WP_001568041.1 DNA methylase -
IS499_RS29025 () 131020..131250 - 231 WP_001568040.1 hypothetical protein -
IS499_RS29030 () 131313..131984 - 672 WP_013214012.1 plasmid partitioning/stability family protein -
IS499_RS29035 () 131987..132958 - 972 WP_004152353.1 mediator of plasmid stability -
IS499_RS29040 () 133207..134694 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
IS499_RS29045 () 135102..135533 + 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
IS499_RS29050 () 135533..136804 + 1272 WP_013214011.1 Y-family DNA polymerase -
IS499_RS29055 () 136886..137860 - 975 WP_011977819.1 ParB/RepB/Spo0J family partition protein -
IS499_RS29060 () 137860..139065 - 1206 WP_011977818.1 AAA family ATPase -
IS499_RS29065 () 140175..141041 - 867 WP_004118283.1 replication initiation protein -
IS499_RS29070 () 141577..141690 + 114 WP_014343462.1 hypothetical protein -
IS499_RS29075 () 141819..142076 + 258 WP_013214010.1 hypothetical protein -
IS499_RS29080 () 142122..142901 - 780 WP_013214009.1 site-specific integrase -
IS499_RS29085 () 143085..144089 - 1005 WP_011977814.1 hypothetical protein -
IS499_RS29090 () 144119..144322 - 204 WP_011977813.1 hypothetical protein -
IS499_RS29095 () 144368..144889 - 522 WP_013214008.1 hypothetical protein -
IS499_RS29100 () 144947..145339 - 393 WP_011977811.1 hypothetical protein -
IS499_RS29105 () 145376..146320 - 945 WP_011977810.1 hypothetical protein -
IS499_RS29110 () 146481..146726 - 246 Protein_191 hypothetical protein -
IS499_RS29115 () 147127..147417 - 291 WP_000648897.1 hypothetical protein -
IS499_RS29120 () 147417..148541 - 1125 WP_000386705.1 DUF4238 domain-containing protein -
IS499_RS29125 () 148576..150168 - 1593 WP_001350003.1 hypothetical protein -
IS499_RS29130 () 150390..151148 - 759 WP_000494510.1 hypothetical protein -
IS499_RS29135 () 151160..151651 - 492 WP_000528930.1 hypothetical protein -
IS499_RS29140 () 151850..153421 - 1572 WP_029392005.1 IS66 family transposase ISCro1 Transposase
IS499_RS29145 () 153441..153788 - 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
IS499_RS29150 () 153788..154465 - 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
IS499_RS29155 () 154633..154872 + 240 WP_000371884.1 hypothetical protein -
IS499_RS29160 () 155062..157134 - 2073 WP_001084041.1 DUF87 domain-containing protein -
IS499_RS29165 () 157131..158522 - 1392 WP_000085084.1 SIR2 family protein -
IS499_RS29170 () 158599..159084 - 486 Protein_203 Tn3 family transposase TnpR_Tn3 Transposase
IS499_RS29175 () 159148..159852 + 705 WP_001067845.1 IS6 family transposase IS26 Transposase
IS499_RS29180 () 159939..160286 - 348 WP_000142451.1 hypothetical protein -
IS499_RS29185 () 160415..160750 + 336 WP_001080730.1 colicin 1A immunity protein -
IS499_RS29190 () 160772..161131 - 360 WP_085452786.1 colicin -
IS499_RS29195 () 161205..161902 + 698 Protein_208 IS1 family transposase IS1R Transposase
IS499_RS29200 () 161952..162227 - 276 WP_000421257.1 type II toxin-antitoxin system RelE/ParE family toxin -
IS499_RS29205 () 162227..162511 - 285 WP_001178089.1 ribbon-helix-helix domain-containing protein -
IS499_RS29210 () 163153..164157 - 1005 WP_021546935.1 IS110 family transposase IS4321R Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance