MGE detailed information
MGE type: Conjugative plasmid MGE length: 133575 bp
Accession: NZ_CP064225 Location: 1..133575 Organism: Klebsiella pneumoniae strain JX-CR-hvKP-7 Replicon: plasmid pJX7-2
Accession: NZ_CP064225 Location: 1..133575 Organism: Klebsiella pneumoniae strain JX-CR-hvKP-7 Replicon: plasmid pJX7-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IS505_RS28005 () | 183..626 | - | 444 | WP_032440559.1 | plasmid partitioning/stability family protein | - |
| IS505_RS28010 () | 629..1603 | - | 975 | WP_032440558.1 | plasmid segregation protein ParM | - |
| IS505_RS28015 () | 1844..2521 | - | 678 | WP_086556681.1 | tyrosine-type recombinase/integrase | - |
| IS505_RS28020 () | 2651..3136 | - | 486 | WP_032440556.1 | hypothetical protein | - |
| IS505_RS28025 () | 3221..3469 | - | 249 | WP_032440555.1 | helix-turn-helix domain-containing protein | - |
| IS505_RS28030 () | 4254..5312 | + | 1059 | WP_032440554.1 | hypothetical protein | - |
| IS505_RS28035 () | 5305..5514 | + | 210 | WP_032440553.1 | hypothetical protein | - |
| IS505_RS28040 () | 5586..5870 | + | 285 | WP_015344981.1 | hypothetical protein | - |
| IS505_RS28045 () | 6010..6651 | - | 642 | WP_032440552.1 | hypothetical protein | - |
| IS505_RS28050 () | 6887..7216 | + | 330 | WP_000493286.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| IS505_RS28055 () | 7197..7478 | + | 282 | WP_000780222.1 | helix-turn-helix transcriptional regulator | - |
| IS505_RS28060 () | 7625..8199 | - | 575 | Protein_11 | DUF4113 domain-containing protein | - |
| IS505_RS28065 () | 8250..8840 | + | 591 | WP_012477564.1 | plasmid pRiA4b ORF-3 family protein | - |
| IS505_RS28070 () | 8977..9549 | + | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| IS505_RS28075 () | 9586..10977 | + | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| IS505_RS28080 () | 11010..11438 | + | 429 | Protein_15 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| IS505_RS28085 () | 11757..12413 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| IS505_RS28090 () | 12808..13961 | + | 1154 | Protein_17 | IS3 family transposase ISAs17 | Transposase |
| IS505_RS28095 () | 14010..14867 | - | 858 | WP_012477595.1 | Beta-lactamase TEM | ARG |
| IS505_RS28100 () | 14932..16035 | - | 1104 | WP_040212993.1 | peptidoglycan synthetase FtsI | - |
| IS505_RS28105 () | 16042..19008 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| IS505_RS28110 () | 19012..19572 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| IS505_RS28115 () | 19964..20581 | + | 618 | Protein_22 | replication protein | - |
| IS505_RS28120 () | 21115..21393 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| IS505_RS28125 () | 21504..21929 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| IS505_RS28130 () | 22057..22212 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| IS505_RS28135 () | 22258..22554 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| IS505_RS28140 () | 22658..23539 | + | 882 | Protein_27 | IS1182 family transposase ISKpn6 | Transposase |
| IS505_RS28145 () | 23789..24670 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| IS505_RS28150 () | 24946..25926 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| IS505_RS28155 () | 26049..26510 | - | 462 | Protein_30 | Tn3 family transposase TnpR_Tn3 | Transposase |
| IS505_RS28160 () | 26562..27266 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS505_RS28165 () | 27331..28503 | - | 1173 | Protein_32 | transposase | - |
| IS505_RS28170 () | 28578..29246 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| IS505_RS28175 () | 29282..29518 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| IS505_RS28180 () | 29515..29877 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| IS505_RS28185 () | 29895..31589 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| IS505_RS28190 () | 31641..32063 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| IS505_RS28195 () | 32099..32374 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| IS505_RS28200 () | 32388..32738 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| IS505_RS28205 () | 32810..33244 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| IS505_RS28210 () | 33323..34327 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| IS505_RS28215 () | 34607..34879 | - | 273 | Protein_42 | IS5 family transposase ISPan1 | Transposase |
| IS505_RS28220 () | 34908..35605 | - | 698 | Protein_43 | IS1 family transposase ISKpn14 | Transposase |
| IS505_RS28225 () | 35861..36883 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
| IS505_RS28230 () | 36868..38430 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
| IS505_RS28235 () | 38504..38920 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| IS505_RS28240 () | 38917..39147 | - | 231 | WP_001261282.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| IS505_RS28245 () | 39104..39343 | + | 240 | Protein_48 | hypothetical protein | - |
| IS505_RS28250 () | 39492..40493 | + | 1002 | WP_000785695.1 | DUF4238 domain-containing protein | - |
| IS505_RS28255 () | 40667..41011 | - | 345 | WP_000792769.1 | hypothetical protein | - |
| IS505_RS28260 () | 41509..41763 | - | 255 | WP_000678528.1 | hypothetical protein | - |
| IS505_RS28265 () | 41813..42739 | - | 927 | WP_001290414.1 | hypothetical protein | - |
| IS505_RS28270 () | 43298..43516 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| IS505_RS28275 () | 43518..43823 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| IS505_RS28280 () | 43824..44633 | + | 810 | WP_000016963.1 | site-specific integrase | - |
| IS505_RS28285 () | 44805..44999 | + | 195 | Protein_56 | colicin M immunity protein | - |
| IS505_RS28290 () | 45055..45752 | + | 698 | Protein_57 | IS1 family transposase IS1G | Transposase |
| IS505_RS28295 () | 45768..46358 | - | 591 | Protein_58 | colicin-B | - |
| IS505_RS28300 () | 46538..46964 | + | 427 | Protein_59 | tyrosine-type recombinase/integrase | - |
| IS505_RS28305 () | 47156..47431 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| IS505_RS28310 () | 47425..48069 | - | 645 | WP_000633913.1 | AAA family ATPase | - |
| IS505_RS28315 () | 48298..49269 | + | 972 | WP_001103697.1 | hypothetical protein | - |
| IS505_RS28320 () | 49274..49666 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| IS505_RS28325 () | 49671..50942 | - | 1272 | WP_000457496.1 | Y-family DNA polymerase | - |
| IS505_RS28330 () | 50942..51379 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| IS505_RS28335 () | 51376..51624 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| IS505_RS28340 () | 52042..52944 | + | 903 | WP_001302618.1 | DUF1281 domain-containing protein | - |
| IS505_RS28345 () | 52948..53253 | + | 306 | WP_032155763.1 | hypothetical protein | - |
| IS505_RS28350 () | 53329..54012 | + | 684 | WP_000086160.1 | DNA methylase | - |
| IS505_RS28355 () | 54013..54234 | + | 222 | WP_001104887.1 | hypothetical protein | - |
| IS505_RS28360 () | 54246..54680 | + | 435 | WP_021547622.1 | DUF1380 family protein | - |
| IS505_RS28365 () | 54725..55495 | + | 771 | WP_001006225.1 | hypothetical protein | - |
| IS505_RS28370 () | 55909..56334 | + | 426 | WP_089079046.1 | antirestriction protein | - |
| IS505_RS28375 () | 56381..56803 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| IS505_RS28380 () | 56800..56991 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| IS505_RS28385 () | 57305..58972 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| IS505_RS28390 () | 60372..60602 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| IS505_RS28395 () | 60654..62015 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| IS505_RS28400 () | 62062..62625 | + | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| IS505_RS28405 () | 63474..64001 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| IS505_RS28410 () | 64059..64292 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| IS505_RS28415 () | 64353..66376 | + | 2024 | Protein_82 | ParB/RepB/Spo0J family partition protein | - |
| IS505_RS28420 () | 66445..66879 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| IS505_RS28425 () | 66876..67595 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 67607..67831 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 67607..67831 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 67607..67831 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 67607..67831 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 67764..67829 | - | 66 | - | - | Antitoxin Detail |
| IS505_RS28430 () | 67875..68033 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| IS505_RS28435 () | 68271..68648 | - | 378 | Protein_86 | hypothetical protein | - |
| IS505_RS28440 () | 69198..69902 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS505_RS28445 () | 69977..70252 | + | 276 | Protein_88 | PAS domain-containing protein | - |
| IS505_RS28450 () | 70316..71020 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS505_RS28455 () | 71054..71578 | - | 525 | WP_094818827.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| IS505_RS28460 () | 71971..72984 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| IS505_RS28465 () | 73140..73613 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| IS505_RS28470 () | 73860..74564 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS505_RS28475 () | 74616..76382 | + | 1767 | Protein_94 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| IS505_RS28480 () | 76461..77465 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| IS505_RS28485 () | 77647..77823 | - | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| IS505_RS28490 () | 78153..78968 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| IS505_RS28495 () | 79055..79297 | + | 243 | Protein_98 | phosphoglucosamine mutase | - |
| IS505_RS28500 () | 79251..79502 | - | 252 | WP_071881958.1 | hypothetical protein | - |
| IS505_RS28505 () | 79533..81026 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| IS505_RS28510 () | 81237..81461 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| IS505_RS28515 () | 81458..82195 | - | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| IS505_RS28520 () | 82661..83365 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS505_RS28525 () | 83430..84872 | + | 1443 | Protein_104 | Methyl-accepting chemotaxis protein McpQ | VF |
| IS505_RS28530 () | 85020..85799 | - | 780 | WP_108970993.1 | Y-family DNA polymerase | - |
| IS505_RS28535 () | 85799..86224 | - | 426 | WP_045325066.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| IS505_RS28540 () | 86302..87789 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| IS505_RS28545 () | 88204..88818 | - | 615 | WP_032440595.1 | DUF2913 family protein | - |
| IS505_RS28550 () | 89725..90324 | - | 600 | WP_157843645.1 | RepA protein | - |
| IS505_RS28555 () | 90926..91177 | - | 252 | WP_113394424.1 | hypothetical protein | - |
| IS505_RS28560 () | 91189..91722 | - | 534 | WP_032440594.1 | Phospholipase D | VF |
| IS505_RS28565 () | 91768..93960 | - | 2193 | WP_032440593.1 | hypothetical protein | VF |
| IS505_RS28570 () | 93962..95053 | - | 1092 | WP_050597336.1 | thioredoxin fold domain-containing protein | - |
| IS505_RS28575 () | 95064..96482 | - | 1419 | WP_063666705.1 | hypothetical protein | - |
| IS505_RS28580 () | 96584..97207 | - | 624 | WP_032440592.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| IS505_RS28585 () | 97273..99417 | - | 2145 | WP_032440591.1 | DotA/TraY family protein | - |
| IS505_RS28590 () | 99459..100040 | - | 582 | WP_050597335.1 | conjugal transfer protein TraX | - |
| IS505_RS28595 () | 100037..101233 | - | 1197 | WP_032440590.1 | conjugal transfer protein TraW | - |
| IS505_RS28600 () | 101243..104290 | - | 3048 | WP_032440589.1 | conjugal transfer protein | - |
| IS505_RS28605 () | 104300..104863 | - | 564 | WP_045325070.1 | hypothetical protein | - |
| IS505_RS28610 () | 104907..105308 | - | 402 | WP_032440588.1 | hypothetical protein | - |
| IS505_RS28615 () | 105364..105897 | - | 534 | WP_032440587.1 | conjugal transfer protein TraQ | - |
| IS505_RS28620 () | 105907..106626 | - | 720 | WP_050597333.1 | conjugal transfer protein TraP | - |
| IS505_RS28625 () | 106633..107973 | - | 1341 | WP_032440586.1 | conjugal transfer protein TraO | - |
| IS505_RS28630 () | 107977..109080 | - | 1104 | WP_077264204.1 | hypothetical protein | VF |
| IS505_RS28635 () | 109091..109795 | - | 705 | WP_045325071.1 | DotI/IcmL/TraM family protein | - |
| IS505_RS28640 () | 109831..110184 | - | 354 | WP_032440584.1 | hypothetical protein | - |
| IS505_RS28645 () | 110218..113631 | - | 3414 | WP_052145516.1 | hypothetical protein | - |
| IS505_RS28650 () | 113649..113915 | - | 267 | WP_032440577.1 | hypothetical protein | VF |
| IS505_RS28655 () | 113912..115099 | - | 1188 | WP_077255878.1 | putative protein YggR | VF |
| IS505_RS28660 () | 115077..115895 | - | 819 | WP_032440576.1 | hypothetical protein | VF |
| IS505_RS28665 () | 115892..116320 | - | 429 | WP_087638882.1 | DotD/TraH family lipoprotein | - |
| IS505_RS28670 () | 116382..116861 | - | 480 | WP_032440574.1 | hypothetical protein | VF |
| IS505_RS28675 () | 117593..117820 | - | 228 | WP_032440573.1 | hypothetical protein | - |
| IS505_RS28680 () | 118430..119272 | + | 843 | WP_032440572.1 | response regulator | - |
| IS505_RS28685 () | 119275..120261 | + | 987 | WP_045325075.1 | hypothetical protein | - |
| IS505_RS28690 () | 120254..120748 | + | 495 | WP_032440571.1 | molybdopterin-dependent oxidoreductase | - |
| IS505_RS28695 () | 120745..122439 | + | 1695 | WP_032440570.1 | hybrid sensor histidine kinase/response regulator | - |
| IS505_RS28700 () | 122720..124648 | - | 1929 | WP_032440569.1 | Protein TraI | Relaxase |
| IS505_RS28705 () | 124651..124962 | - | 312 | WP_016162079.1 | hypothetical protein | - |
| IS505_RS28710 () | 125252..125671 | + | 420 | WP_058674280.1 | hypothetical protein | - |
| IS505_RS28715 () | 125963..126283 | - | 321 | WP_032440568.1 | hypothetical protein | - |
| IS505_RS28720 () | 126337..126570 | - | 234 | WP_032440567.1 | hypothetical protein | - |
| IS505_RS28725 () | 126727..127011 | - | 285 | WP_032440566.1 | hypothetical protein | - |
| IS505_RS28730 () | 127055..127495 | - | 441 | WP_032440565.1 | antirestriction protein | - |
| IS505_RS28735 () | 127695..128000 | - | 306 | WP_023285840.1 | hypothetical protein | - |
| IS505_RS28740 () | 128062..128472 | - | 411 | WP_004187342.1 | DUF1380 family protein | - |
| IS505_RS28745 () | 128557..128793 | - | 237 | WP_086556679.1 | hypothetical protein | - |
| IS505_RS28750 () | 129092..129322 | - | 231 | WP_040213052.1 | hypothetical protein | - |
| IS505_RS28755 () | 129420..129758 | - | 339 | WP_004187354.1 | hypothetical protein | - |
| IS505_RS28760 () | 129948..130808 | - | 861 | WP_032440562.1 | DUF4942 domain-containing protein | - |
| IS505_RS28765 () | 130881..131060 | - | 180 | WP_023285836.1 | hypothetical protein | - |
| IS505_RS28770 () | 131703..131969 | - | 267 | WP_023285835.1 | helix-turn-helix domain-containing protein | - |
| IS505_RS28775 () | 132014..132463 | - | 450 | WP_032440561.1 | Mov34/MPN/PAD-1 family protein | - |
| IS505_RS28780 () | 132581..133078 | - | 498 | WP_032440560.1 | hypothetical protein | - |
| IS505_RS28785 () | 133071..133316 | - | 246 | WP_040212973.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|