MGE detailed information
MGE type: Conjugative plasmid MGE length: 146760 bp
Accession: NZ_CP064219 Location: 1..146760 Organism: Klebsiella pneumoniae strain JX-CR-hvKP-8 Replicon: plasmid pJX8-2
Accession: NZ_CP064219 Location: 1..146760 Organism: Klebsiella pneumoniae strain JX-CR-hvKP-8 Replicon: plasmid pJX8-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IS494_RS27850 () | 429..1415 | + | 987 | WP_045325075.1 | hypothetical protein | - |
| IS494_RS27855 () | 1408..1902 | + | 495 | WP_032440571.1 | molybdopterin-dependent oxidoreductase | - |
| IS494_RS27860 () | 1899..3593 | + | 1695 | WP_032440570.1 | hybrid sensor histidine kinase/response regulator | - |
| IS494_RS27865 () | 3874..5802 | - | 1929 | WP_032440569.1 | Protein TraI | Relaxase |
| IS494_RS27870 () | 5805..6116 | - | 312 | WP_016162079.1 | hypothetical protein | - |
| IS494_RS27875 () | 6406..6825 | + | 420 | WP_058674280.1 | hypothetical protein | - |
| IS494_RS27880 () | 7117..7437 | - | 321 | WP_032440568.1 | hypothetical protein | - |
| IS494_RS27885 () | 7491..7724 | - | 234 | WP_032440567.1 | hypothetical protein | - |
| IS494_RS27890 () | 7881..8165 | - | 285 | WP_032440566.1 | hypothetical protein | - |
| IS494_RS27895 () | 8209..8649 | - | 441 | WP_032440565.1 | antirestriction protein | - |
| IS494_RS27900 () | 8849..9154 | - | 306 | WP_023285840.1 | hypothetical protein | - |
| IS494_RS27905 () | 9216..9626 | - | 411 | WP_004187342.1 | DUF1380 family protein | - |
| IS494_RS27910 () | 9711..9947 | - | 237 | WP_086556679.1 | hypothetical protein | - |
| IS494_RS27915 () | 10246..10476 | - | 231 | WP_040213052.1 | hypothetical protein | - |
| IS494_RS27920 () | 10574..10912 | - | 339 | WP_004187354.1 | hypothetical protein | - |
| IS494_RS27925 () | 11102..11962 | - | 861 | WP_032440562.1 | DUF4942 domain-containing protein | - |
| IS494_RS27930 () | 12035..12214 | - | 180 | WP_023285836.1 | hypothetical protein | - |
| IS494_RS27935 () | 12857..13123 | - | 267 | WP_023285835.1 | helix-turn-helix domain-containing protein | - |
| IS494_RS27940 () | 13168..13617 | - | 450 | WP_032440561.1 | Mov34/MPN/PAD-1 family protein | - |
| IS494_RS27945 () | 13735..14232 | - | 498 | WP_032440560.1 | hypothetical protein | - |
| IS494_RS27950 () | 14225..14470 | - | 246 | WP_040212973.1 | hypothetical protein | - |
| IS494_RS27955 () | 14912..15355 | - | 444 | WP_032440559.1 | plasmid partitioning/stability family protein | - |
| IS494_RS27960 () | 15358..16332 | - | 975 | WP_032440558.1 | plasmid segregation protein ParM | - |
| IS494_RS27965 () | 16573..17250 | - | 678 | WP_086556681.1 | tyrosine-type recombinase/integrase | - |
| IS494_RS27970 () | 17380..17865 | - | 486 | WP_032440556.1 | hypothetical protein | - |
| IS494_RS27975 () | 17950..18198 | - | 249 | WP_032440555.1 | helix-turn-helix domain-containing protein | - |
| IS494_RS27980 () | 18983..20041 | + | 1059 | WP_032440554.1 | hypothetical protein | - |
| IS494_RS27985 () | 20034..20243 | + | 210 | WP_032440553.1 | hypothetical protein | - |
| IS494_RS27990 () | 20315..20599 | + | 285 | WP_015344981.1 | hypothetical protein | - |
| IS494_RS27995 () | 20739..21380 | - | 642 | WP_032440552.1 | hypothetical protein | - |
| IS494_RS28000 () | 21616..21945 | + | 330 | WP_000493286.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| IS494_RS28005 () | 21926..22207 | + | 282 | WP_000780222.1 | helix-turn-helix transcriptional regulator | - |
| IS494_RS28010 () | 22354..22929 | - | 576 | WP_077256884.1 | DUF4113 domain-containing protein | - |
| IS494_RS28015 () | 22980..23570 | + | 591 | WP_012477564.1 | plasmid pRiA4b ORF-3 family protein | - |
| IS494_RS28020 () | 23707..24279 | + | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| IS494_RS28025 () | 24316..25707 | + | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| IS494_RS28030 () | 25740..26168 | + | 429 | Protein_37 | recombinase family protein | - |
| IS494_RS28035 () | 26487..27143 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| IS494_RS28040 () | 27538..28691 | + | 1154 | Protein_39 | IS3 family transposase ISAs17 | Transposase |
| IS494_RS28045 () | 28740..29597 | - | 858 | WP_012477595.1 | Beta-lactamase TEM | ARG |
| IS494_RS28050 () | 29662..30765 | - | 1104 | WP_040212993.1 | peptidoglycan synthetase FtsI | - |
| IS494_RS28055 () | 30772..33738 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| IS494_RS28060 () | 33742..34302 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| IS494_RS28065 () | 34694..35311 | + | 618 | Protein_44 | replication protein | - |
| IS494_RS28070 () | 35845..36123 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| IS494_RS28075 () | 36234..36659 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| IS494_RS28080 () | 36787..36942 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| IS494_RS28085 () | 36988..37284 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| IS494_RS28090 () | 37388..38269 | + | 882 | Protein_49 | IS1182 family transposase ISKpn6 | Transposase |
| IS494_RS28095 () | 38519..39400 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| IS494_RS28100 () | 39676..40656 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| IS494_RS28105 () | 40779..41240 | - | 462 | Protein_52 | Tn3 family transposase TnpR_Tn3 | Transposase |
| IS494_RS28110 () | 41292..41996 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS494_RS28115 () | 42060..42335 | - | 276 | Protein_54 | PAS domain-containing protein | - |
| IS494_RS28120 () | 42410..43114 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS494_RS28125 () | 43664..44041 | + | 378 | Protein_56 | hypothetical protein | - |
| IS494_RS28130 () | 44279..44437 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 44481..44705 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 44481..44705 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 44481..44705 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 44481..44705 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| IS494_RS28135 () | 44717..45436 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| IS494_RS28140 () | 45433..45867 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| IS494_RS28145 () | 45936..47959 | - | 2024 | Protein_60 | ParB/RepB/Spo0J family partition protein | - |
| IS494_RS28150 () | 48020..48253 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| IS494_RS28155 () | 48311..48838 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| IS494_RS28160 () | 49693..50256 | - | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| IS494_RS28165 () | 50303..51664 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| IS494_RS28170 () | 51716..51946 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| IS494_RS28175 () | 53346..55013 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| IS494_RS28180 () | 55327..55518 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| IS494_RS28185 () | 55515..55937 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| IS494_RS28190 () | 55984..56409 | - | 426 | WP_089079046.1 | antirestriction protein | - |
| IS494_RS28195 () | 56823..57593 | - | 771 | WP_001006225.1 | hypothetical protein | - |
| IS494_RS28200 () | 57638..58072 | - | 435 | WP_021547622.1 | DUF1380 family protein | - |
| IS494_RS28205 () | 58084..58305 | - | 222 | WP_001104887.1 | hypothetical protein | - |
| IS494_RS28210 () | 58306..58989 | - | 684 | WP_000086160.1 | DNA methylase | - |
| IS494_RS28215 () | 59065..59370 | - | 306 | WP_032155763.1 | hypothetical protein | - |
| IS494_RS28220 () | 59374..60276 | - | 903 | WP_001302618.1 | DUF1281 domain-containing protein | - |
| IS494_RS28225 () | 60694..60942 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| IS494_RS28230 () | 60939..61376 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| IS494_RS28235 () | 61376..62647 | + | 1272 | WP_000457496.1 | Y-family DNA polymerase | - |
| IS494_RS28240 () | 62652..63044 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| IS494_RS28245 () | 63049..64020 | - | 972 | WP_001103697.1 | hypothetical protein | - |
| IS494_RS28250 () | 64249..64893 | + | 645 | WP_000633913.1 | AAA family ATPase | - |
| IS494_RS28255 () | 64887..65162 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| IS494_RS28260 () | 65354..65780 | - | 427 | Protein_83 | tyrosine-type recombinase/integrase | - |
| IS494_RS28265 () | 65960..66550 | + | 591 | Protein_84 | colicin-B | - |
| IS494_RS28270 () | 66566..67263 | - | 698 | Protein_85 | IS1 family transposase IS1G | Transposase |
| IS494_RS28275 () | 67319..67513 | - | 195 | Protein_86 | colicin M immunity protein | - |
| IS494_RS28280 () | 67685..68494 | - | 810 | WP_000016963.1 | site-specific integrase | - |
| IS494_RS28285 () | 68495..68800 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| IS494_RS28290 () | 68802..69020 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| IS494_RS28295 () | 69579..70505 | + | 927 | WP_001290414.1 | hypothetical protein | - |
| IS494_RS28300 () | 70555..70809 | + | 255 | WP_000678528.1 | hypothetical protein | - |
| IS494_RS28305 () | 71307..71651 | + | 345 | WP_000792769.1 | hypothetical protein | - |
| IS494_RS28310 () | 71825..72826 | - | 1002 | WP_000785695.1 | DUF4238 domain-containing protein | - |
| IS494_RS28315 () | 72975..73214 | - | 240 | Protein_94 | hypothetical protein | - |
| IS494_RS28320 () | 73171..73401 | + | 231 | WP_001261282.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| IS494_RS28325 () | 73398..73814 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| IS494_RS28330 () | 73888..75450 | + | 1563 | WP_004206609.1 | AAA family ATPase | - |
| IS494_RS28335 () | 75435..76457 | + | 1023 | WP_000361404.1 | helicase UvrD | - |
| IS494_RS28340 () | 76713..77410 | + | 698 | Protein_99 | IS1 family transposase ISKpn14 | Transposase |
| IS494_RS28345 () | 77439..77711 | + | 273 | Protein_100 | transposase | - |
| IS494_RS28350 () | 77991..78995 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| IS494_RS28355 () | 79074..79508 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| IS494_RS28360 () | 79580..79930 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| IS494_RS28365 () | 79944..80219 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| IS494_RS28370 () | 80255..80677 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| IS494_RS28375 () | 80729..82423 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| IS494_RS28380 () | 82441..82803 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| IS494_RS28385 () | 82800..83036 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| IS494_RS28390 () | 83072..83740 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| IS494_RS28395 () | 83815..84987 | + | 1173 | Protein_110 | transposase | - |
| IS494_RS28400 () | 85052..85756 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS494_RS28405 () | 85810..86133 | - | 324 | Protein_112 | class II aldolase/adducin family protein | - |
| IS494_RS28410 () | 86126..87378 | - | 1253 | Protein_113 | four-carbon acid sugar kinase family protein | - |
| IS494_RS28415 () | 87390..88292 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| IS494_RS28420 () | 88554..89315 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| IS494_RS28425 () | 89336..90196 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| IS494_RS28430 () | 90333..90401 | + | 69 | Protein_117 | IS6 family transposase | - |
| IS494_RS28435 () | 90437..92188 | - | 1752 | Protein_118 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| IS494_RS28440 () | 92177..92584 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| IS494_RS28445 () | 92722..93606 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| IS494_RS28450 () | 93638..94837 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| IS494_RS28455 () | 94943..95593 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| IS494_RS28460 () | 95771..96475 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS494_RS28465 () | 96619..97260 | - | 642 | WP_001011939.1 | Chloramphenicol acetyltransferase 2 | ARG |
| IS494_RS28470 () | 97410..97910 | - | 501 | WP_001239317.1 | hypothetical protein | - |
| IS494_RS28475 () | 97990..98694 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS494_RS28480 () | 98728..99252 | - | 525 | WP_094818827.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| IS494_RS28485 () | 99645..100658 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| IS494_RS28490 () | 100814..101287 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| IS494_RS28495 () | 101534..102238 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS494_RS28500 () | 102290..104056 | + | 1767 | Protein_131 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| IS494_RS28505 () | 104135..105139 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| IS494_RS28510 () | 105321..105497 | - | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| IS494_RS28515 () | 105827..106642 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| IS494_RS28520 () | 106729..106971 | + | 243 | Protein_135 | phosphoglucosamine mutase | - |
| IS494_RS28525 () | 106925..107176 | - | 252 | WP_071881958.1 | hypothetical protein | - |
| IS494_RS28530 () | 107207..108700 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| IS494_RS28535 () | 108911..109135 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| IS494_RS28540 () | 109132..109869 | - | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| IS494_RS28545 () | 110355..110495 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| IS494_RS28550 () | 110501..111205 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IS494_RS28555 () | 111230..112786 | + | 1557 | WP_053897648.1 | Aerotaxis receptor | VF |
| IS494_RS28560 () | 112934..113713 | - | 780 | WP_108970993.1 | Y-family DNA polymerase | - |
| IS494_RS28565 () | 113713..114138 | - | 426 | WP_045325066.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| IS494_RS28570 () | 114216..115703 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| IS494_RS28575 () | 116118..116732 | - | 615 | WP_032440595.1 | DUF2913 family protein | - |
| IS494_RS28580 () | 117639..118238 | - | 600 | WP_157843645.1 | RepA protein | - |
| IS494_RS28585 () | 118840..119091 | - | 252 | WP_113394424.1 | hypothetical protein | - |
| IS494_RS28590 () | 119103..119636 | - | 534 | WP_032440594.1 | Phospholipase D | VF |
| IS494_RS28595 () | 119682..121874 | - | 2193 | WP_032440593.1 | hypothetical protein | VF |
| IS494_RS28600 () | 121876..122967 | - | 1092 | WP_050597336.1 | thioredoxin fold domain-containing protein | - |
| IS494_RS28605 () | 122978..124396 | - | 1419 | WP_063666705.1 | hypothetical protein | - |
| IS494_RS28610 () | 124498..125121 | - | 624 | WP_032440592.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| IS494_RS28615 () | 125187..127331 | - | 2145 | WP_032440591.1 | DotA/TraY family protein | - |
| IS494_RS28620 () | 127373..127954 | - | 582 | WP_050597335.1 | conjugal transfer protein TraX | - |
| IS494_RS28625 () | 127951..129147 | - | 1197 | WP_032440590.1 | conjugal transfer protein TraW | - |
| IS494_RS28630 () | 129157..132204 | - | 3048 | WP_032440589.1 | conjugal transfer protein | - |
| IS494_RS28635 () | 132214..132777 | - | 564 | WP_045325070.1 | hypothetical protein | - |
| IS494_RS28640 () | 132821..133222 | - | 402 | WP_032440588.1 | hypothetical protein | - |
| IS494_RS28645 () | 133278..133811 | - | 534 | WP_032440587.1 | conjugal transfer protein TraQ | - |
| IS494_RS28650 () | 133821..134540 | - | 720 | WP_050597333.1 | conjugal transfer protein TraP | - |
| IS494_RS28655 () | 134547..135887 | - | 1341 | WP_032440586.1 | conjugal transfer protein TraO | - |
| IS494_RS28660 () | 135891..136994 | - | 1104 | WP_077264204.1 | hypothetical protein | VF |
| IS494_RS28665 () | 137005..137709 | - | 705 | WP_045325071.1 | DotI/IcmL/TraM family protein | - |
| IS494_RS28670 () | 137745..138098 | - | 354 | WP_032440584.1 | hypothetical protein | - |
| IS494_RS28675 () | 138132..141545 | - | 3414 | WP_052145516.1 | hypothetical protein | - |
| IS494_RS28680 () | 141563..141829 | - | 267 | WP_032440577.1 | hypothetical protein | VF |
| IS494_RS28685 () | 141826..143013 | - | 1188 | WP_077255878.1 | putative protein YggR | VF |
| IS494_RS28690 () | 142991..143809 | - | 819 | WP_032440576.1 | hypothetical protein | VF |
| IS494_RS28695 () | 143806..144234 | - | 429 | WP_087638882.1 | DotD/TraH family lipoprotein | - |
| IS494_RS28700 () | 144296..144775 | - | 480 | WP_032440574.1 | hypothetical protein | VF |
| IS494_RS28705 () | 145507..145734 | - | 228 | WP_032440573.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|