MGE detailed information
MGE type: Conjugative plasmid MGE length: 111472 bp
Accession: NZ_CP060971 Location: 1..111472 Organism: Escherichia coli strain EC5 Replicon: plasmid pEC5-3
Accession: NZ_CP060971 Location: 1..111472 Organism: Escherichia coli strain EC5 Replicon: plasmid pEC5-3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H9193_RS24100 () | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| H9193_RS24105 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| H9193_RS24110 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H9193_RS24115 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H9193_RS24120 () | 3383..3798 | + | 416 | Protein_4 | IS1-like element IS1B family transposase | - |
| H9193_RS24125 () | 3834..4379 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| H9193_RS24130 () | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H9193_RS24135 () | 5214..5423 | + | 210 | Protein_7 | site-specific DNA-methyltransferase | - |
| H9193_RS24140 () | 5428..8064 | + | 2637 | WP_023281054.1 | DEAD/DEAH box helicase family protein | - |
| H9193_RS24145 () | 8107..8691 | - | 585 | WP_023281055.1 | mobilization protein MobX | - |
| H9193_RS24150 () | 8704..9507 | - | 804 | Protein_10 | Mobilization protein A | Relaxase |
| H9193_RS24155 () | 9496..9672 | + | 177 | Protein_11 | IS6 family transposase IS26 | Transposase |
| H9193_RS24160 () | 9729..10325 | + | 597 | WP_000583524.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| H9193_RS24165 () | 11936..12664 | - | 729 | WP_152921961.1 | replication initiation protein | - |
| H9193_RS24170 () | 12670..13374 | - | 705 | WP_102204227.1 | IS6 family transposase IS15DI | Transposase |
| H9193_RS24175 () | 13573..13896 | - | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| H9193_RS24180 () | 14001..15038 | + | 1038 | WP_044502555.1 | permease | - |
| H9193_RS24185 () | 15331..15948 | - | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| H9193_RS24190 () | 16140..17696 | - | 1557 | WP_000818556.1 | AAA family ATPase | - |
| H9193_RS24195 () | 17959..18549 | - | 591 | WP_000194575.1 | hypothetical protein | - |
| H9193_RS24200 () | 18549..18806 | - | 258 | WP_000343085.1 | hypothetical protein | - |
| H9193_RS24205 () | 19160..21298 | + | 2139 | WP_000350638.1 | AAA family ATPase | - |
| H9193_RS24210 () | 21460..21876 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H9193_RS24215 () | 21873..22103 | - | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| H9193_RS24220 () | 22399..22689 | + | 291 | WP_000111771.1 | hypothetical protein | - |
| H9193_RS24225 () | 22679..23578 | + | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| H9193_RS24230 () | 23628..25853 | - | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| H9193_RS24235 () | 25855..26943 | - | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| H9193_RS24240 () | 27154..27858 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H9193_RS24245 () | 27910..29676 | + | 1767 | Protein_29 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| H9193_RS24250 () | 29755..30759 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| H9193_RS24255 () | 31031..31117 | - | 87 | Protein_31 | Arm DNA-binding domain-containing protein | - |
| H9193_RS24260 () | 31447..32262 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| H9193_RS24265 () | 32323..33126 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| H9193_RS24270 () | 33126..33962 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| H9193_RS24275 () | 34268..34510 | + | 243 | WP_000844627.1 | transposase | - |
| H9193_RS24280 () | 34542..35192 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| H9193_RS24285 () | 35298..36497 | + | 1200 | WP_032153701.1 | Tetracycline resistance protein, class C | ARG |
| H9193_RS24290 () | 36464..36652 | - | 189 | Protein_38 | IS91 family transposase | - |
| H9193_RS24295 () | 36764..37069 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| H9193_RS24300 () | 37097..38311 | - | 1215 | WP_000214122.1 | Bicyclomycin resistance protein | ARG |
| H9193_RS24305 () | 38528..39412 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| H9193_RS24310 () | 39443..40936 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| H9193_RS24315 () | 41147..41371 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| H9193_RS24320 () | 41368..42105 | - | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| H9193_RS24325 () | 42591..42731 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| H9193_RS24330 () | 42737..43441 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H9193_RS24335 () | 43506..44186 | - | 681 | Protein_47 | IS91 family transposase ISAzo26 | Transposase |
| H9193_RS24340 () | 44458..45162 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H9193_RS24345 () | 45217..45642 | + | 426 | Protein_49 | TetR/AcrR family transcriptional regulator | - |
| H9193_RS24350 () | 45662..46450 | + | 789 | WP_014839978.1 | winged helix-turn-helix domain-containing protein | - |
| H9193_RS24355 () | 46450..46968 | + | 519 | WP_014839979.1 | FidL-like protein | - |
| H9193_RS24360 () | 46973..47389 | - | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| H9193_RS24365 () | 47775..48479 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H9193_RS24370 () | 48529..49272 | + | 744 | Protein_54 | Beta-lactamase TEM | ARG |
| H9193_RS24375 () | 49531..50007 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| H9193_RS24380 () | 50054..50929 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| H9193_RS24385 () | 51351..52055 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H9193_RS24390 () | 52121..52186 | + | 66 | Protein_58 | IS1 family transposase | - |
| H9193_RS24395 () | 53635..53869 | + | 235 | Protein_59 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| H9193_RS24400 () | 53997..54200 | + | 204 | Protein_60 | hypothetical protein | - |
| H9193_RS24405 () | 54401..54751 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| H9193_RS24410 () | 54754..55716 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| H9193_RS24415 () | 55863..56156 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| H9193_RS24420 () | 56233..56916 | + | 684 | WP_000085883.1 | DNA methylase | - |
| H9193_RS24425 () | 56917..57138 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| H9193_RS24430 () | 57152..57586 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| H9193_RS24435 () | 57637..58413 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| H9193_RS24440 () | 58831..59256 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| H9193_RS24445 () | 59303..59725 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| H9193_RS24450 () | 59722..59913 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| H9193_RS24455 () | 60127..60282 | + | 156 | WP_159420149.1 | hypothetical protein | - |
| H9193_RS24460 () | 60951..61181 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| H9193_RS24465 () | 61233..62594 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| H9193_RS24470 () | 62641..63204 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| H9193_RS24475 () | 63290..63757 | - | 468 | Protein_75 | hypothetical protein | - |
| H9193_RS24480 () | 64059..64586 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| H9193_RS24485 () | 64644..64877 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| H9193_RS24490 () | 64938..66961 | + | 2024 | Protein_78 | ParB/RepB/Spo0J family partition protein | - |
| H9193_RS24495 () | 67030..67464 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| H9193_RS24500 () | 67461..68223 | + | 763 | Protein_80 | plasmid SOS inhibition protein A | - |
| - () | 68192..68416 | + | 225 | NuclAT_0 | - | - |
| - () | 68192..68416 | + | 225 | NuclAT_0 | - | - |
| - () | 68192..68416 | + | 225 | NuclAT_0 | - | - |
| - () | 68192..68416 | + | 225 | NuclAT_0 | - | - |
| H9193_RS24505 () | 68201..68380 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - | 68349..68414 | - | 66 | - | - | Antitoxin Detail |
| H9193_RS24510 () | 68402..68551 | + | 150 | Protein_82 | plasmid maintenance protein Mok | - |
| H9193_RS24515 () | 68493..68618 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H9193_RS24520 () | 68937..69233 | - | 297 | Protein_84 | hypothetical protein | - |
| H9193_RS24525 () | 69533..69829 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| H9193_RS24530 () | 69940..70761 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| H9193_RS24535 () | 71058..71705 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| H9193_RS24540 () | 71982..72365 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| H9193_RS24545 () | 72556..73242 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| H9193_RS24550 () | 73336..73563 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| H9193_RS24555 () | 73597..73962 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| H9193_RS24560 () | 73977..74288 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H9193_RS24565 () | 74310..74876 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| H9193_RS24570 () | 74863..75591 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| H9193_RS24575 () | 75591..77018 | + | 1428 | WP_167731963.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| H9193_RS24580 () | 77008..77598 | + | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| H9193_RS24585 () | 77585..77803 | + | 219 | WP_042040319.1 | conjugal transfer protein TrbD | - |
| H9193_RS24590 () | 77790..79403 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| H9193_RS24595 () | 79434..79784 | - | 351 | WP_053892389.1 | IS66 family transposase ISEc23 | Transposase |
| H9193_RS24600 () | 79781..80206 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| H9193_RS24605 () | 80334..80585 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| H9193_RS24610 () | 80582..81097 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H9193_RS24615 () | 81232..81453 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| H9193_RS24620 () | 81613..84240 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| H9193_RS24625 () | 84237..84623 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| H9193_RS24630 () | 84620..85252 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| H9193_RS24635 () | 85249..86241 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| H9193_RS24640 () | 86268..86576 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| H9193_RS24645 () | 86639..87160 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| H9193_RS24650 () | 87187..87825 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H9193_RS24655 () | 87822..88193 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| H9193_RS24660 () | 88219..88641 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| H9193_RS24665 () | 88638..90488 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H9193_RS24670 () | 90515..90772 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| H9193_RS24675 () | 90765..91508 | + | 744 | WP_015059017.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H9193_RS24680 () | 91669..91905 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H9193_RS24685 () | 91892..92437 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H9193_RS24690 () | 92427..92741 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| H9193_RS24695 () | 92695..93087 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| H9193_RS24700 () | 93074..94447 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| H9193_RS24705 () | 94444..97260 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| H9193_RS24710 () | 97293..97814 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| H9193_RS24715 () | 97839..98570 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| H9193_RS24720 () | 98773..99510 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| H9193_RS24725 () | 99561..101813 | + | 2253 | WP_061093448.1 | type IV conjugative transfer system coupling protein TraD | - |
| H9193_RS24730 () | 101813..107083 | + | 5271 | WP_061093447.1 | Multifunctional conjugation protein TraI | Relaxase |
| H9193_RS24735 () | 107103..107849 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| H9193_RS24740 () | 107904..108464 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| H9193_RS24745 () | 108596..108796 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| H9193_RS24750 () | 109182..109781 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| H9193_RS24755 () | 109843..110175 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - () | 110376..110435 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 110376..110435 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 110376..110435 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 110376..110435 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| H9193_RS24760 () | 110480..110629 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| H9193_RS24765 () | 110913..111161 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|