MGE detailed information
MGE type: Conjugative plasmid MGE length: 138915 bp
Accession: NZ_CP059948 Location: 1..138915 Organism: Escherichia coli strain 268.2 Replicon: plasmid p1
Accession: NZ_CP059948 Location: 1..138915 Organism: Escherichia coli strain 268.2 Replicon: plasmid p1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H5C70_RS23370 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| H5C70_RS23375 () | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| H5C70_RS23380 () | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| H5C70_RS23385 () | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| H5C70_RS23390 () | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| H5C70_RS23395 () | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| H5C70_RS23400 () | 7425..7583 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| H5C70_RS23405 () | 7767..8980 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| H5C70_RS23410 () | 9128..9453 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| H5C70_RS23415 () | 10434..11621 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| H5C70_RS23420 () | 11618..13558 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| H5C70_RS23425 () | 13562..14932 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| H5C70_RS23430 () | 15406..15600 | + | 195 | Protein_12 | IS200-IS605 family transposase IS200C | Transposase |
| H5C70_RS23435 () | 15729..16670 | - | 942 | Protein_13 | hypothetical protein | - |
| H5C70_RS23440 () | 16905..18294 | - | 1390 | Protein_14 | ISNCY family transposase ISKpn21 | Transposase |
| H5C70_RS23445 () | 18604..18753 | - | 150 | Protein_15 | IS3 family transposase IS2 | Transposase |
| H5C70_RS23450 () | 18931..19419 | - | 489 | Protein_16 | cobalamin biosynthesis protein CobW | - |
| H5C70_RS23455 () | 19480..20184 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H5C70_RS23460 () | 20237..20740 | - | 504 | Protein_18 | IS4 family transposase IS10R | Transposase |
| H5C70_RS23465 () | 20883..21743 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| H5C70_RS23470 () | 21756..22037 | + | 282 | WP_094315732.1 | hypothetical protein | - |
| H5C70_RS23475 () | 22071..22775 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| H5C70_RS23480 () | 22830..23030 | + | 201 | Protein_22 | IS6 family transposase IS26 | Transposase |
| H5C70_RS23485 () | 23561..24217 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| H5C70_RS23490 () | 24612..25627 | + | 1016 | Protein_24 | IS3 family transposase ISEc36 | Transposase |
| H5C70_RS23495 () | 25670..28465 | - | 2796 | Protein_25 | Tn3 family transposase TnpA_Tn3 | Transposase |
| H5C70_RS23500 () | 28479..28811 | + | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| H5C70_RS23505 () | 28858..29733 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| H5C70_RS23510 () | 29989..31251 | - | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| H5C70_RS23515 () | 31433..31576 | - | 144 | WP_095742999.1 | DUF4158 domain-containing protein | - |
| H5C70_RS23520 () | 31655..32337 | - | 683 | Protein_30 | IS6 family transposase IS15DI | Transposase |
| H5C70_RS23525 () | 32397..33211 | + | 815 | Protein_31 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| H5C70_RS23530 () | 33267..33509 | + | 243 | WP_000844627.1 | transposase | - |
| H5C70_RS23535 () | 33541..34191 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| H5C70_RS23540 () | 34297..35496 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| H5C70_RS23545 () | 35528..36412 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| H5C70_RS23550 () | 36550..36957 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| H5C70_RS23555 () | 36946..38697 | + | 1752 | Protein_37 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| H5C70_RS23560 () | 38912..40684 | - | 1773 | WP_001262767.1 | DUF262 domain-containing protein | - |
| H5C70_RS23565 () | 40969..41370 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H5C70_RS23570 () | 41303..41560 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H5C70_RS23575 () | 41653..42306 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| H5C70_RS23580 () | 43245..44099 | - | 855 | Protein_42 | incFII family plasmid replication initiator RepA | - |
| H5C70_RS23585 () | 44092..44166 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| H5C70_RS23590 () | 44401..44658 | - | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| H5C70_RS23595 () | 45063..46085 | + | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| H5C70_RS23600 () | 46557..46910 | + | 354 | WP_000005489.1 | hypothetical protein | - |
| H5C70_RS23605 () | 47323..47901 | - | 579 | WP_032152936.1 | DUF2726 domain-containing protein | - |
| H5C70_RS23610 () | 47934..48628 | + | 695 | Protein_48 | IS1 family transposase | - |
| H5C70_RS23615 () | 48737..49099 | + | 363 | WP_059330006.1 | IS66 family insertion sequence hypothetical protein | - |
| H5C70_RS23620 () | 49096..49446 | + | 351 | WP_000624725.1 | IS66 family transposase ISEc47 | Transposase |
| H5C70_RS23625 () | 49477..49698 | + | 222 | WP_000080227.1 | IS66 family transposase ISEc43 | Transposase |
| H5C70_RS23630 () | 49650..49991 | + | 342 | Protein_52 | transposase | - |
| H5C70_RS23635 () | 50055..50534 | - | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| H5C70_RS23640 () | 50615..52018 | - | 1404 | WP_000514417.1 | YfcC family protein | - |
| H5C70_RS23645 () | 52066..53070 | - | 1005 | WP_000154545.1 | Ornithine carbamoyltransferase | VF |
| H5C70_RS23650 () | 53155..54066 | - | 912 | WP_000440183.1 | carbamate kinase | - |
| H5C70_RS23655 () | 54077..55297 | - | 1221 | WP_000410951.1 | arginine deiminase | - |
| H5C70_RS23660 () | 56190..56672 | + | 483 | Protein_58 | VENN motif pre-toxin domain-containing protein | - |
| H5C70_RS23665 () | 56618..57064 | - | 447 | Protein_59 | incFII family plasmid replication initiator RepA | - |
| H5C70_RS23670 () | 57057..57131 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| H5C70_RS23675 () | 57367..57624 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| H5C70_RS23680 () | 57908..58114 | - | 207 | WP_015387399.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 58101..58162 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 58101..58162 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 58101..58162 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 58101..58162 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| H5C70_RS23685 () | 58301..58483 | - | 183 | WP_000968309.1 | hypothetical protein | - |
| H5C70_RS23690 () | 58584..59200 | + | 617 | Protein_64 | IS1 family transposase IS1S | Transposase |
| H5C70_RS23695 () | 59238..60809 | - | 1572 | WP_023149734.1 | IS66 family transposase ISCro1 | Transposase |
| H5C70_RS23700 () | 60829..61176 | - | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| H5C70_RS23705 () | 61176..61853 | - | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| H5C70_RS23710 () | 61908..61997 | + | 90 | Protein_68 | IS1 family transposase | - |
| H5C70_RS23715 () | 62298..62510 | - | 213 | WP_005012601.1 | hypothetical protein | - |
| H5C70_RS23720 () | 62644..63204 | - | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| H5C70_RS23725 () | 63259..64005 | - | 747 | WP_023149624.1 | conjugal transfer pilus acetylase TraX | - |
| H5C70_RS23730 () | 64025..69145 | - | 5121 | WP_013362805.1 | Multifunctional conjugation protein TraI | Relaxase |
| H5C70_RS23735 () | 69145..71307 | - | 2163 | WP_044067743.1 | type IV conjugative transfer system coupling protein TraD | - |
| H5C70_RS23740 () | 71559..72290 | - | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| H5C70_RS23745 () | 72304..72813 | - | 510 | WP_000628100.1 | conjugal transfer entry exclusion protein TraS | - |
| H5C70_RS23750 () | 72810..75635 | - | 2826 | WP_001553826.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H5C70_RS23755 () | 75632..77005 | - | 1374 | WP_021518370.1 | conjugal transfer protein TraH | - |
| H5C70_RS23760 () | 76992..77384 | - | 393 | WP_000164675.1 | F-type conjugal transfer protein TrbF | - |
| H5C70_RS23765 () | 77338..77712 | - | 375 | WP_071788165.1 | P-type conjugative transfer protein TrbJ | - |
| H5C70_RS23770 () | 77642..78196 | - | 555 | WP_001553830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H5C70_RS23775 () | 78183..78467 | - | 285 | WP_000624105.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H5C70_RS23780 () | 78548..78883 | + | 336 | WP_000415571.1 | hypothetical protein | - |
| H5C70_RS23785 () | 78864..79205 | - | 342 | WP_000556794.1 | conjugal transfer protein TrbA | - |
| H5C70_RS23790 () | 79219..79962 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H5C70_RS23795 () | 79955..80212 | - | 258 | WP_000864312.1 | conjugal transfer protein TrbE | - |
| H5C70_RS23800 () | 80239..82047 | - | 1809 | WP_000821840.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H5C70_RS23805 () | 82044..82682 | - | 639 | WP_021518374.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H5C70_RS23810 () | 82691..83683 | - | 993 | WP_000830180.1 | conjugal transfer pilus assembly protein TraU | - |
| H5C70_RS23815 () | 83680..84312 | - | 633 | WP_182917306.1 | type-F conjugative transfer system protein TraW | - |
| H5C70_RS23820 () | 84309..84695 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| H5C70_RS23825 () | 84692..87319 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| H5C70_RS23830 () | 87479..87700 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| H5C70_RS23835 () | 87835..88350 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H5C70_RS23840 () | 88347..88598 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| H5C70_RS23845 () | 88610..88840 | - | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| H5C70_RS23850 () | 88794..89384 | - | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| H5C70_RS23855 () | 89374..90801 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| H5C70_RS23860 () | 90801..91505 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| H5C70_RS23865 () | 91516..92082 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| H5C70_RS23870 () | 92104..92415 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H5C70_RS23875 () | 92430..92795 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| H5C70_RS23880 () | 92828..93223 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| H5C70_RS23885 () | 93322..94011 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| H5C70_RS23890 () | 94198..94581 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| H5C70_RS23895 () | 94898..95500 | + | 603 | WP_013362798.1 | hypothetical protein | VF |
| H5C70_RS23900 () | 95797..96618 | - | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| H5C70_RS23905 () | 96736..97023 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| H5C70_RS23910 () | 97943..98101 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 98145..98369 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 98145..98369 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 98145..98369 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 98145..98369 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| H5C70_RS23915 () | 98181..98369 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| H5C70_RS23920 () | 98381..99100 | - | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| H5C70_RS23925 () | 99097..99531 | - | 435 | WP_000845937.1 | conjugation system SOS inhibitor PsiB | - |
| H5C70_RS23930 () | 99586..99783 | - | 198 | Protein_112 | hypothetical protein | - |
| H5C70_RS23935 () | 99811..100044 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| H5C70_RS23940 () | 100112..100651 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| H5C70_RS23945 () | 100677..100883 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| H5C70_RS23950 () | 101293..101511 | - | 219 | WP_001496291.1 | hypothetical protein | - |
| H5C70_RS23955 () | 101537..102102 | - | 566 | Protein_117 | class I SAM-dependent methyltransferase | - |
| H5C70_RS23960 () | 102150..103511 | - | 1362 | WP_094315706.1 | DUF3560 domain-containing protein | - |
| H5C70_RS23965 () | 103563..103793 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| H5C70_RS23970 () | 104305..104553 | + | 249 | WP_071781657.1 | hypothetical protein | - |
| H5C70_RS23975 () | 104825..105016 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| H5C70_RS23980 () | 105013..105435 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| H5C70_RS23985 () | 105482..105784 | - | 303 | WP_001666994.1 | antirestriction protein | - |
| H5C70_RS23990 () | 106321..107091 | - | 771 | WP_001006251.1 | hypothetical protein | - |
| H5C70_RS23995 () | 107136..107570 | - | 435 | WP_001546462.1 | DUF1380 family protein | - |
| H5C70_RS24000 () | 107584..107805 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| H5C70_RS24005 () | 107806..108489 | - | 684 | WP_040110341.1 | DNA methylase | - |
| H5C70_RS24010 () | 108566..108870 | - | 305 | Protein_128 | hypothetical protein | - |
| H5C70_RS24015 () | 108874..109776 | - | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| H5C70_RS24020 () | 110514..111485 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H5C70_RS24025 () | 111485..112651 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| H5C70_RS24030 () | 113239..113994 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| H5C70_RS24035 () | 114716..115522 | - | 807 | WP_000016970.1 | site-specific integrase | - |
| H5C70_RS24040 () | 115523..115828 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| H5C70_RS24045 () | 115830..116048 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| H5C70_RS24050 () | 116608..116838 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| H5C70_RS24055 () | 116835..117251 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H5C70_RS24060 () | 117326..118891 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| H5C70_RS24065 () | 118876..119898 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| H5C70_RS24070 () | 120152..120849 | - | 698 | Protein_140 | IS1 family transposase IS1R | Transposase |
| H5C70_RS24075 () | 121375..123576 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| H5C70_RS24080 () | 123658..124935 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| H5C70_RS24085 () | 124932..126674 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| H5C70_RS24090 () | 126674..127621 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| H5C70_RS24095 () | 127622..129346 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| H5C70_RS24100 () | 129482..130675 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| H5C70_RS24105 () | 131055..131435 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| H5C70_RS24110 () | 131776..132189 | - | 414 | Protein_148 | phosphopyruvate hydratase | - |
| H5C70_RS24115 () | 132187..132444 | + | 258 | Protein_149 | Tn3 family transposase | - |
| H5C70_RS24120 () | 132678..133535 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| H5C70_RS24125 () | 133532..134389 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| H5C70_RS24130 () | 134386..135213 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| H5C70_RS24135 () | 135213..136127 | - | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| H5C70_RS24140 () | 136483..137180 | + | 698 | Protein_154 | IS1 family transposase IS1R | Transposase |
| H5C70_RS24145 () | 137191..137683 | - | 493 | Protein_155 | DUF4113 domain-containing protein | - |
| H5C70_RS24150 () | 137744..137848 | - | 105 | Protein_156 | AAA family ATPase | - |
| H5C70_RS24155 () | 137850..138173 | - | 324 | Protein_157 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|