NZ_CP0591261..146488

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 146488 bp
Accession: NZ_CP059126        Location: 1..146488         Organism: Escherichia coli strain EC45       Replicon: plasmid pEc45_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0X93_RS23915 (1) 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
H0X93_RS23920 (1263) 1263..2003 - 741 WP_001066953.1 tyrosine-type recombinase/integrase -
H0X93_RS23925 (2124) 2124..2312 - 189 WP_001309252.1 hypothetical protein -
H0X93_RS23930 (2679) 2679..3848 + 1170 WP_001072358.1 hypothetical protein -
H0X93_RS23935 (4074) 4074..4249 - 176 Protein_4 IS3 family transposase -
H0X93_RS23940 (4695) 4695..4967 - 273 WP_001322642.1 adhesin biosynthesis transcription regulatory family protein -
H0X93_RS23945 (5504) 5504..5928 - 425 Protein_6 transposase -
H0X93_RS23950 (6210) 6210..8180 + 1971 WP_001496335.1 TonB-dependent hemoglobin/transferrin/lactoferrin family receptor -
H0X93_RS23955 (8187) 8187..8978 + 792 WP_000977394.1 DUF4198 domain-containing protein -
H0X93_RS23960 (9041) 9041..9649 - 609 Protein_9 IS66 family transposase -
H0X93_RS23965 (9717) 9717..10499 - 783 WP_001317493.1 IS21-like element IS100kyp family helper ATPase IstB -
H0X93_RS23970 (10580) 10580..11284 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
H0X93_RS23975 (11428) 11428..11982 + 555 WP_063840321.1 fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5 -
H0X93_RS23980 (12113) 12113..12943 + 831 WP_001334766.1 oxacillin-hydrolyzing class D beta-lactamase OXA-1 -
H0X93_RS23985 (13081) 13081..13521 + 441 Protein_14 CatB-related O-acetyltransferase -
H0X93_RS23990 (13575) 13575..14279 - 705 WP_001067855.1 IS6-like element IS26 family transposase -
H0X93_RS23995 (14345) 14345..14632 + 288 Protein_16 transposase -
H0X93_RS24000 (14888) 14888..15763 + 876 WP_000239590.1 extended-spectrum class A beta-lactamase CTX-M-15 -
H0X93_RS24005 (15810) 15810..16103 - 294 WP_116961751.1 WbuC family cupin fold metalloprotein -
H0X93_RS24010 (16168) 16168..18387 + 2220 Protein_19 Tn3-like element Tn3 family transposase -
H0X93_RS24015 (18464) 18464..19168 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
H0X93_RS24020 (19222) 19222..20270 - 1049 Protein_21 IS3 family transposase -
H0X93_RS24025 (20362) 20362..20904 - 543 WP_002063889.1 AAA family ATPase -
H0X93_RS24030 (20917) 20917..21777 - 861 WP_000557452.1 aminoglycoside N-acetyltransferase AAC(3)-IIe -
H0X93_RS24035 (21884) 21884..22588 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
H0X93_RS24040 (22641) 22641..22949 + 309 Protein_25 IS1 family transposase -
H0X93_RS24045 (22964) 22964..24127 + 1164 Protein_26 IS4-like element ISVsa5 family transposase -
H0X93_RS24050 (24137) 24137..24553 - 417 WP_000275180.1 AraC family transcriptional regulator -
H0X93_RS24055 (24641) 24641..25234 + 594 WP_000428546.1 tetracyline resistance-associated transcriptional repressor TetC -
H0X93_RS24060 (25347) 25347..26552 - 1206 WP_001089068.1 tetracycline efflux MFS transporter Tet(B) -
H0X93_RS24065 (26634) 26634..27257 + 624 WP_000088605.1 tetracycline resistance transcriptional repressor TetR(B) -
H0X93_RS24070 (27235) 27235..27921 - 687 WP_001284954.1 winged helix-turn-helix domain-containing protein -
H0X93_RS24075 (27929) 27929..28315 - 387 WP_000460651.1 hypothetical protein -
H0X93_RS24080 (28308) 28308..28571 - 264 WP_049802299.1 antibiotic biosynthesis monooxygenase -
H0X93_RS24090 (29544) 29544..30203 + 660 WP_000412211.1 type A-1 chloramphenicol O-acetyltransferase -
H0X93_RS24095 (30404) 30404..30781 - 378 WP_000656305.1 GNAT family N-acetyltransferase -
H0X93_RS24100 (30848) 30848..33814 - 2967 WP_001138064.1 Tn3-like element TnAs3 family transposase -
H0X93_RS24105 (33817) 33817..34431 - 615 WP_257623536.1 recombinase family protein -
H0X93_RS24110 (34422) 34422..35126 + 705 WP_001067855.1 IS6-like element IS26 family transposase -
H0X93_RS24115 (35218) 35218..35982 + 765 WP_001389365.1 IS6-like element IS6100 family transposase -
H0X93_RS24120 (36475) 36475..37059 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
H0X93_RS24125 (37059) 37059..38297 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
H0X93_RS24130 (38294) 38294..39199 - 906 WP_000219391.1 Mph(A) family macrolide 2'-phosphotransferase -
H0X93_RS24135 (39321) 39321..40025 - 705 WP_001067855.1 IS6-like element IS26 family transposase -
H0X93_RS24140 (40080) 40080..41501 + 1422 Protein_45 Tn3-like element Tn5403 family transposase -
H0X93_RS24145 (41638) 41638..42039 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
H0X93_RS24150 (41972) 41972..42229 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
H0X93_RS24155 (42322) 42322..42975 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
H0X93_RS24160 (43914) 43914..44771 - 858 WP_032152935.1 incFII family plasmid replication initiator RepA -
H0X93_RS24165 (44764) 44764..44838 - 75 WP_001365705.1 RepA leader peptide Tap -
H0X93_RS24170 (45073) 45073..45330 - 258 WP_000083821.1 replication regulatory protein RepA -
H0X93_RS24175 (45735) 45735..46757 + 1023 WP_000156883.1 IS110 family transposase -
H0X93_RS24180 (47229) 47229..47582 + 354 WP_000005489.1 hypothetical protein -
H0X93_RS24185 (47995) 47995..48573 - 579 WP_032152936.1 DUF2726 domain-containing protein -
H0X93_RS24190 (48606) 48606..49303 + 698 WP_223230354.1 IS1-like element IS1A family transposase -
H0X93_RS24195 (49418) 49418..49774 + 357 WP_000229735.1 transposase -
H0X93_RS24200 (49771) 49771..50121 + 351 WP_000624725.1 IS66 family insertion sequence element accessory protein TnpB -
H0X93_RS24205 (50152) 50152..50373 + 222 WP_000080227.1 hypothetical protein -
H0X93_RS24210 (50325) 50325..50666 + 342 Protein_59 transposase -
H0X93_RS24215 (50730) 50730..51209 - 480 WP_001496175.1 ArgR family transcriptional regulator -
H0X93_RS24220 (51290) 51290..52693 - 1404 WP_000514417.1 YfcC family protein -
H0X93_RS24225 (52741) 52741..53745 - 1005 WP_000154545.1 ornithine carbamoyltransferase -
H0X93_RS24230 (53830) 53830..54741 - 912 WP_000440183.1 carbamate kinase -
H0X93_RS24235 (54752) 54752..55972 - 1221 WP_000410951.1 arginine deiminase -
H0X93_RS24240 (56679) 56679..57293 + 615 Protein_65 VENN motif pre-toxin domain-containing protein -
H0X93_RS24245 (57293) 57293..57739 - 447 Protein_66 plasmid replication initiator RepA -
H0X93_RS24250 (57732) 57732..57806 - 75 WP_032336874.1 RepA leader peptide Tap -
H0X93_RS24255 (58042) 58042..58299 - 258 WP_000083833.1 replication regulatory protein RepA -
H0X93_RS24260 (58583) 58583..58732 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (58776) 58776..58837 + 62 NuclAT_2 - Antitoxin Detail
- (58776) 58776..58837 + 62 NuclAT_2 - Antitoxin Detail
- (58776) 58776..58837 + 62 NuclAT_2 - Antitoxin Detail
- (58776) 58776..58837 + 62 NuclAT_2 - Antitoxin Detail
H0X93_RS24265 (58976) 58976..59158 - 183 WP_000968309.1 hypothetical protein -
H0X93_RS24270 (59259) 59259..59875 + 617 Protein_71 IS1-like element IS1A family transposase -
H0X93_RS24275 (59913) 59913..61484 - 1572 WP_023149734.1 IS66-like element ISCro1 family transposase -
H0X93_RS24280 (61504) 61504..61851 - 348 WP_000624622.1 IS66 family insertion sequence element accessory protein TnpB -
H0X93_RS24285 (61851) 61851..62528 - 678 WP_001339397.1 IS66-like element accessory protein TnpA -
H0X93_RS24290 (62583) 62583..62672 + 90 Protein_75 IS1 family transposase -
H0X93_RS24295 (62973) 62973..63185 - 213 WP_005012601.1 hypothetical protein -
H0X93_RS24300 (63319) 63319..63879 - 561 WP_000139363.1 fertility inhibition protein FinO -
H0X93_RS24305 (63934) 63934..64680 - 747 WP_023149624.1 conjugal transfer pilus acetylase TraX -
H0X93_RS24310 (64700) 64700..65956 - 1257 Protein_79 conjugative transfer relaxase/helicase TraI -
H0X93_RS24315 (66044) 66044..66790 - 747 WP_053906593.1 IS21-like element ISEc12 family helper ATPase IstB -
H0X93_RS24320 (66805) 66805..68346 - 1542 WP_001298859.1 IS21-like element ISEc12 family transposase -
H0X93_RS24325 (68540) 68540..72409 - 3870 Protein_82 conjugative transfer relaxase/helicase TraI -
H0X93_RS24330 (72409) 72409..74598 - 2190 WP_040110343.1 type IV conjugative transfer system coupling protein TraD -
H0X93_RS24335 (74850) 74850..75560 - 711 WP_045227890.1 conjugal transfer complement resistance protein TraT -
H0X93_RS24340 (75595) 75595..76104 - 510 WP_000628100.1 conjugal transfer entry exclusion protein TraS -
H0X93_RS24345 (76101) 76101..78926 - 2826 WP_001553826.1 conjugal transfer mating-pair stabilization protein TraG -
H0X93_RS24350 (78923) 78923..80296 - 1374 WP_021518370.1 conjugal transfer pilus assembly protein TraH -
H0X93_RS24355 (80283) 80283..80675 - 393 WP_000164675.1 F-type conjugal transfer protein TrbF -
H0X93_RS24360 (80629) 80629..80943 - 315 WP_023149603.1 P-type conjugative transfer protein TrbJ -
H0X93_RS24365 (80933) 80933..81487 - 555 WP_001553830.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
H0X93_RS24370 (81474) 81474..81758 - 285 WP_000624105.1 type-F conjugative transfer system pilin chaperone TraQ -
H0X93_RS24375 (81839) 81839..82174 + 336 WP_000415571.1 hypothetical protein -
H0X93_RS24380 (82155) 82155..82496 - 342 WP_000556794.1 conjugal transfer protein TrbA -
H0X93_RS24385 (82510) 82510..83253 - 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
H0X93_RS24390 (83246) 83246..83503 - 258 WP_000864312.1 conjugal transfer protein TrbE -
H0X93_RS24395 (83530) 83530..85338 - 1809 WP_000821840.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
H0X93_RS24400 (85335) 85335..85973 - 639 WP_021518374.1 type-F conjugative transfer system pilin assembly protein TrbC -
H0X93_RS24405 (85982) 85982..86974 - 993 WP_000830180.1 conjugal transfer pilus assembly protein TraU -
H0X93_RS24410 (86971) 86971..87603 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
H0X93_RS24415 (87600) 87600..87986 - 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
H0X93_RS24420 (87983) 87983..90610 - 2628 WP_001064245.1 type IV secretion system protein TraC -
H0X93_RS24425 (90770) 90770..90991 - 222 WP_001278689.1 conjugal transfer protein TraR -
H0X93_RS24430 (91126) 91126..91641 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
H0X93_RS24435 (91638) 91638..91889 - 252 WP_001038342.1 conjugal transfer protein TrbG -
H0X93_RS24440 (91901) 91901..92098 - 198 WP_001324648.1 conjugal transfer protein TrbD -
H0X93_RS24445 (92085) 92085..92675 - 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
H0X93_RS24450 (92665) 92665..94092 - 1428 WP_000146685.1 F-type conjugal transfer pilus assembly protein TraB -
H0X93_RS24455 (94092) 94092..94820 - 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
H0X93_RS24460 (94807) 94807..95373 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
H0X93_RS24465 (95395) 95395..95706 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
H0X93_RS24470 (95721) 95721..96086 - 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
H0X93_RS24475 (96119) 96119..96520 - 402 WP_001369361.1 conjugal transfer relaxosome DNA-bindin protein TraY -
H0X93_RS24480 (96613) 96613..97302 - 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
H0X93_RS24485 (97489) 97489..97872 - 384 WP_001151524.1 conjugal transfer relaxosome DNA-binding protein TraM -
H0X93_RS24490 (98193) 98193..98795 + 603 WP_013362798.1 transglycosylase SLT domain-containing protein -
H0X93_RS24495 (99092) 99092..99913 - 822 WP_001234426.1 DUF932 domain-containing protein -
H0X93_RS24500 (100031) 100031..100318 - 288 WP_000107535.1 hypothetical protein -
H0X93_RS25195 (100343) 100343..100549 - 207 WP_000547968.1 hypothetical protein -
H0X93_RS25200 (100619) 100619..100791 + 173 Protein_119 hypothetical protein -
H0X93_RS25205 (100789) 100789..101019 - 231 WP_071886920.1 hypothetical protein -
H0X93_RS24505 (101239) 101239..101364 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
H0X93_RS25210 (101306) 101306..101455 - 150 Protein_122 plasmid maintenance protein Mok -
- (101441) 101441..101472 - 32 NuclAT_1 - Antitoxin Detail
- (101441) 101441..101472 - 32 NuclAT_1 - Antitoxin Detail
- (101441) 101441..101472 - 32 NuclAT_1 - Antitoxin Detail
- (101441) 101441..101472 - 32 NuclAT_1 - Antitoxin Detail
- (102914) 102914..103111 - 198 NuclAT_0 - -
- (102914) 102914..103111 - 198 NuclAT_0 - -
- (102914) 102914..103111 - 198 NuclAT_0 - -
- (102914) 102914..103111 - 198 NuclAT_0 - -
H0X93_RS24515 (102923) 102923..103111 + 189 WP_001299721.1 hypothetical protein -
H0X93_RS24520 (103080) 103080..103842 - 763 Protein_125 plasmid SOS inhibition protein A -
H0X93_RS24525 (103839) 103839..104273 - 435 WP_000845937.1 conjugation system SOS inhibitor PsiB -
H0X93_RS24530 (104328) 104328..104525 - 198 Protein_127 hypothetical protein -
H0X93_RS24535 (104553) 104553..104786 - 234 WP_000005990.1 DUF905 family protein -
H0X93_RS24540 (104854) 104854..105351 - 498 WP_042039995.1 single-stranded DNA-binding protein -
H0X93_RS24545 (105501) 105501..107402 - 1902 WP_000936285.1 group II intron reverse transcriptase/maturase -
H0X93_RS24550 (108080) 108080..108286 - 207 WP_000275856.1 hypothetical protein -
H0X93_RS25215 (108526) 108526..108777 - 252 WP_071579736.1 hypothetical protein -
H0X93_RS24555 (108696) 108696..108902 - 207 WP_001774176.1 hypothetical protein -
H0X93_RS24560 (108928) 108928..109493 - 566 Protein_134 class I SAM-dependent methyltransferase -
H0X93_RS24565 (109541) 109541..110902 - 1362 WP_000199439.1 DUF3560 domain-containing protein -
H0X93_RS24570 (110954) 110954..111184 - 231 WP_000218642.1 hypothetical protein -
H0X93_RS24575 (111696) 111696..111944 + 249 WP_071781657.1 hypothetical protein -
H0X93_RS24580 (112216) 112216..112407 - 192 WP_001027495.1 hypothetical protein -
H0X93_RS24585 (112404) 112404..112826 - 423 WP_000271685.1 DUF1380 family protein -
H0X93_RS24590 (112873) 112873..113298 - 426 WP_001546490.1 antirestriction protein -
H0X93_RS24595 (113712) 113712..114482 - 771 WP_001006251.1 hypothetical protein -
H0X93_RS24600 (114527) 114527..115045 - 519 WP_223349485.1 DUF1380 family protein -
H0X93_RS24605 (114975) 114975..115196 - 222 WP_001104873.1 hypothetical protein -
H0X93_RS24610 (115197) 115197..115880 - 684 WP_032181561.1 DNA methylase -
H0X93_RS24615 (115957) 115957..116268 - 312 WP_012615291.1 hypothetical protein -
H0X93_RS24620 (116265) 116265..117167 - 903 WP_064766247.1 DUF1281 domain-containing protein -
H0X93_RS24625 (117905) 117905..118876 - 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
H0X93_RS24630 (118876) 118876..120042 - 1167 WP_000772446.1 plasmid-partitioning protein SopA -
H0X93_RS24635 (120630) 120630..121385 - 756 WP_000852146.1 replication initiation protein RepE -
H0X93_RS24640 (122107) 122107..122913 - 807 WP_000016970.1 site-specific integrase -
H0X93_RS24645 (122914) 122914..123219 - 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
H0X93_RS24650 (123221) 123221..123439 - 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
H0X93_RS24655 (123999) 123999..124229 + 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
H0X93_RS24660 (124226) 124226..124642 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
H0X93_RS24665 (124717) 124717..126282 + 1566 WP_001128474.1 AAA family ATPase -
H0X93_RS24670 (126267) 126267..127289 + 1023 WP_000361402.1 helicase UvrD -
H0X93_RS24675 (127543) 127543..128229 - 687 Protein_157 IS1 family transposase -
H0X93_RS24680 (128755) 128755..130956 - 2202 WP_000973519.1 ferric aerobactin receptor IutA -
H0X93_RS24685 (130982) 130982..132315 - 1334 Protein_159 NADPH-dependent L-lysine N(6)-monooxygenase IucD -
H0X93_RS24690 (132312) 132312..134054 - 1743 WP_001015721.1 NIS family aerobactin synthetase IucC -
H0X93_RS24695 (134054) 134054..135001 - 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase IucB -
H0X93_RS24700 (135002) 135002..136726 - 1725 WP_000602863.1 NIS family aerobactin synthetase IucA -
H0X93_RS24705 (136862) 136862..138055 + 1194 WP_000095526.1 MFS transporter -
H0X93_RS24710 (138435) 138435..138815 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
H0X93_RS24715 (139156) 139156..139569 - 414 Protein_165 phosphopyruvate hydratase -
H0X93_RS24720 (139567) 139567..139824 + 258 Protein_166 transposase -
H0X93_RS24725 (140058) 140058..140915 - 858 WP_000968139.1 iron/manganese ABC transporter permease subunit SitD -
H0X93_RS24730 (140912) 140912..141769 - 858 WP_001101723.1 iron/manganese ABC transporter permease subunit SitC -
H0X93_RS24735 (141766) 141766..142593 - 828 WP_000983710.1 iron/manganese ABC transporter ATP-binding protein SitB -
H0X93_RS24740 (142593) 142593..143507 - 915 WP_000949005.1 iron/manganese ABC transporter substrate-binding protein SitA -
H0X93_RS24745 (143863) 143863..144560 + 698 WP_103215986.1 IS1-like element IS1A family transposase -
H0X93_RS24750 (144740) 144740..145253 - 514 Protein_172 DUF4113 domain-containing protein -
H0X93_RS24755 (145314) 145314..145418 - 105 Protein_173 AAA family ATPase -
H0X93_RS24760 (145420) 145420..145743 - 324 Protein_174 helix-turn-helix domain-containing protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance