MGE detailed information
MGE type: Conjugative plasmid MGE length: 125110 bp
Accession: NZ_CP055168 Location: 1..125110 Organism: Shigella flexneri strain STEFF_24 Replicon: plasmid unnamed1
Accession: NZ_CP055168 Location: 1..125110 Organism: Shigella flexneri strain STEFF_24 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ50_RS23540 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| HUZ50_RS23545 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| HUZ50_RS23550 (2124) | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| HUZ50_RS23555 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| HUZ50_RS23560 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| HUZ50_RS23565 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| HUZ50_RS23570 (6637) | 6637..7334 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| HUZ50_RS23575 (7351) | 7351..7548 | - | 198 | Protein_7 | colicin V | - |
| HUZ50_RS23580 (7526) | 7526..7762 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| HUZ50_RS23585 (8226) | 8226..8507 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| HUZ50_RS23590 (8680) | 8680..8847 | + | 168 | Protein_10 | colicin-B | - |
| HUZ50_RS23595 (8865) | 8865..9392 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| HUZ50_RS23600 (9636) | 9636..10451 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| HUZ50_RS23605 (10501) | 10501..10854 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| HUZ50_RS23610 (11032) | 11032..11823 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| HUZ50_RS23615 (11820) | 11820..12509 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| HUZ50_RS23620 (12553) | 12553..12903 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| HUZ50_RS23625 (13448) | 13448..14536 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| HUZ50_RS23630 (14538) | 14538..16763 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| HUZ50_RS23635 (16813) | 16813..17712 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| HUZ50_RS23640 (17702) | 17702..17992 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| HUZ50_RS23645 (18288) | 18288..18518 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| HUZ50_RS23650 (18515) | 18515..18931 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HUZ50_RS23655 (19093) | 19093..21231 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| HUZ50_RS23660 (21585) | 21585..21842 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| HUZ50_RS23665 (21842) | 21842..22432 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| HUZ50_RS23670 (22695) | 22695..24155 | + | 1461 | WP_202745975.1 | AAA family ATPase | - |
| HUZ50_RS23675 (24443) | 24443..25060 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| HUZ50_RS23680 (25353) | 25353..26432 | - | 1080 | WP_001089727.1 | permease | - |
| HUZ50_RS23685 (26537) | 26537..26860 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| HUZ50_RS23690 (27021) | 27021..27341 | + | 321 | Protein_30 | NAD(P)H-dependent oxidoreductase | - |
| HUZ50_RS23695 (27394) | 27394..28098 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ50_RS23700 (28164) | 28164..29507 | + | 1344 | Protein_32 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ50_RS23705 (29558) | 29558..30262 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ50_RS23710 (30328) | 30328..30612 | + | 285 | Protein_34 | IS6 family transposase IS26 | Transposase |
| HUZ50_RS23715 (30802) | 30802..31617 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HUZ50_RS23720 (31768) | 31768..32472 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ50_RS23725 (32920) | 32920..33933 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HUZ50_RS23730 (34089) | 34089..34562 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| HUZ50_RS23735 (34632) | 34632..35336 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ50_RS23740 (35784) | 35784..36797 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HUZ50_RS23745 (36953) | 36953..37426 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| HUZ50_RS23750 (37496) | 37496..38200 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ50_RS23755 (38254) | 38254..38568 | + | 315 | Protein_43 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HUZ50_RS23760 (38571) | 38571..41537 | + | 2967 | WP_072794601.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| HUZ50_RS23765 (41616) | 41616..42620 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| HUZ50_RS23770 (42892) | 42892..42978 | - | 87 | Protein_46 | Arm DNA-binding domain-containing protein | - |
| HUZ50_RS23775 (43308) | 43308..44123 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| HUZ50_RS23780 (44184) | 44184..44987 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HUZ50_RS23785 (44987) | 44987..45823 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| HUZ50_RS23790 (46054) | 46054..46509 | - | 456 | Protein_50 | class A beta-lactamase | - |
| HUZ50_RS23795 (46573) | 46573..47277 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ50_RS23800 (47380) | 47380..47937 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HUZ50_RS23805 (48101) | 48101..48319 | + | 219 | WP_001143771.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ50_RS23810 (48501) | 48501..49763 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| HUZ50_RS23815 (50019) | 50019..50894 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| HUZ50_RS23820 (50941) | 50941..51234 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| HUZ50_RS23825 (51299) | 51299..53518 | + | 2220 | Protein_57 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ50_RS23830 (53595) | 53595..54299 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ50_RS23835 (54365) | 54365..54910 | + | 546 | Protein_59 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ50_RS23840 (54946) | 54946..55361 | - | 416 | Protein_60 | IS1-like element IS1B family transposase | - |
| HUZ50_RS23845 (55610) | 55610..56011 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HUZ50_RS23850 (55944) | 55944..56201 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HUZ50_RS23855 (56294) | 56294..56947 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HUZ50_RS23860 (57886) | 57886..58743 | - | 858 | WP_239612969.1 | incFII family plasmid replication initiator RepA | - |
| HUZ50_RS23865 (58736) | 58736..59218 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| HUZ50_RS23870 (59211) | 59211..59258 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| HUZ50_RS23875 (59249) | 59249..59500 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| HUZ50_RS23880 (59517) | 59517..59774 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| HUZ50_RS23885 (60058) | 60058..60207 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (60251) | 60251..60312 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (60251) | 60251..60312 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (60251) | 60251..60312 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (60251) | 60251..60312 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| HUZ50_RS23890 (60568) | 60568..60642 | - | 75 | Protein_70 | endonuclease | - |
| HUZ50_RS23895 (60888) | 60888..61100 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| HUZ50_RS23900 (61236) | 61236..61796 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| HUZ50_RS23905 (61899) | 61899..62759 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| HUZ50_RS23910 (62818) | 62818..63564 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| HUZ50_RS23915 (63584) | 63584..68854 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| HUZ50_RS23920 (68936) | 68936..69163 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| HUZ50_RS23925 (69163) | 69163..69561 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HUZ50_RS23930 (69570) | 69570..71723 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| HUZ50_RS23935 (71976) | 71976..72707 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| HUZ50_RS23940 (72739) | 72739..73236 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| HUZ50_RS23945 (73252) | 73252..76074 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HUZ50_RS23950 (76071) | 76071..77444 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| HUZ50_RS23955 (77444) | 77444..77824 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| HUZ50_RS23960 (77811) | 77811..78152 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| HUZ50_RS23965 (78082) | 78082..78627 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HUZ50_RS23970 (78614) | 78614..78898 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HUZ50_RS23975 (78979) | 78979..79293 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| HUZ50_RS23980 (79295) | 79295..79642 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| HUZ50_RS23985 (79658) | 79658..80401 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HUZ50_RS23990 (80394) | 80394..80651 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| HUZ50_RS23995 (80678) | 80678..82486 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HUZ50_RS24000 (82483) | 82483..83121 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HUZ50_RS24005 (83130) | 83130..84122 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| HUZ50_RS24010 (84119) | 84119..84751 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| HUZ50_RS24015 (84748) | 84748..85134 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| HUZ50_RS24020 (85131) | 85131..87758 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| HUZ50_RS24025 (87918) | 87918..88139 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| HUZ50_RS24030 (88274) | 88274..88789 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HUZ50_RS24035 (88786) | 88786..89037 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| HUZ50_RS24040 (89049) | 89049..89246 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| HUZ50_RS24045 (89233) | 89233..89823 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| HUZ50_RS24050 (89813) | 89813..91240 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| HUZ50_RS24055 (91240) | 91240..91968 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| HUZ50_RS24060 (91955) | 91955..92344 | - | 390 | Protein_104 | type IV conjugative transfer system protein TraE | - |
| HUZ50_RS24065 (92438) | 92438..93666 | + | 1229 | WP_089541817.1 | IS3 family transposase IS2 | Transposase |
| HUZ50_RS24070 (93678) | 93678..93857 | - | 180 | Protein_106 | TraE/TraK family type IV conjugative transfer system protein | - |
| HUZ50_RS24075 (93879) | 93879..94190 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HUZ50_RS24080 (94205) | 94205..94570 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| HUZ50_RS24085 (94603) | 94603..95004 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| HUZ50_RS24090 (95097) | 95097..95786 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| HUZ50_RS24095 (95973) | 95973..96356 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| HUZ50_RS24100 (96677) | 96677..97279 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| HUZ50_RS24105 (97576) | 97576..98397 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| HUZ50_RS24110 (98515) | 98515..98802 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| HUZ50_RS24115 (98827) | 98827..99033 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| HUZ50_RS24120 (99103) | 99103..99275 | + | 173 | Protein_116 | hypothetical protein | - |
| HUZ50_RS24125 (99273) | 99273..99503 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| HUZ50_RS24130 (99723) | 99723..99848 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUZ50_RS24135 (99790) | 99790..99939 | - | 150 | Protein_119 | plasmid maintenance protein Mok | - |
| - (99925) | 99925..100149 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (99925) | 99925..100149 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (99925) | 99925..100149 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (99925) | 99925..100149 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| HUZ50_RS24140 (99961) | 99961..100149 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| HUZ50_RS24145 (100118) | 100118..100880 | - | 763 | Protein_121 | plasmid SOS inhibition protein A | - |
| HUZ50_RS24150 (100877) | 100877..101311 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| HUZ50_RS24155 (101366) | 101366..101563 | - | 198 | Protein_123 | hypothetical protein | - |
| HUZ50_RS24160 (101591) | 101591..101824 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| HUZ50_RS24165 (101892) | 101892..102431 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| HUZ50_RS24170 (102457) | 102457..102663 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| HUZ50_RS24175 (102733) | 102733..102813 | + | 81 | Protein_127 | hypothetical protein | - |
| HUZ50_RS24180 (102996) | 102996..103165 | - | 170 | Protein_128 | hypothetical protein | - |
| HUZ50_RS24185 (103759) | 103759..104730 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HUZ50_RS24190 (104730) | 104730..105896 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| HUZ50_RS24195 (106196) | 106196..106892 | - | 697 | Protein_131 | IS1 family transposase | - |
| HUZ50_RS24200 (107377) | 107377..109572 | - | 2196 | WP_175267602.1 | Ferric aerobactin receptor | VF |
| HUZ50_RS24205 (109604) | 109604..110937 | - | 1334 | Protein_133 | L-lysine N6-monooxygenase | VF |
| HUZ50_RS24210 (110934) | 110934..112676 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| HUZ50_RS24215 (112676) | 112676..113623 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| HUZ50_RS24220 (113624) | 113624..115348 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| HUZ50_RS24225 (115484) | 115484..116677 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| HUZ50_RS24230 (117057) | 117057..117437 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| HUZ50_RS24235 (117778) | 117778..118191 | - | 414 | Protein_139 | phosphopyruvate hydratase | - |
| HUZ50_RS24240 (118189) | 118189..118446 | + | 258 | Protein_140 | Tn3 family transposase | - |
| HUZ50_RS24245 (118680) | 118680..119537 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| HUZ50_RS24250 (119534) | 119534..120391 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| HUZ50_RS24255 (120388) | 120388..121215 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| HUZ50_RS24260 (121215) | 121215..122129 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| HUZ50_RS24265 (122485) | 122485..123182 | + | 698 | WP_094096600.1 | IS1 family transposase IS1S | Transposase |
| HUZ50_RS24270 (123362) | 123362..123875 | - | 514 | Protein_146 | DUF4113 domain-containing protein | - |
| HUZ50_RS24275 (123936) | 123936..124040 | - | 105 | Protein_147 | AAA family ATPase | - |
| HUZ50_RS24280 (124042) | 124042..124365 | - | 324 | Protein_148 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|