MGE detailed information
MGE type: Conjugative plasmid MGE length: 132056 bp
Accession: NZ_CP055001 Location: 1..132056 Organism: Shigella flexneri strain STIN_80 Replicon: plasmid unnamed1
Accession: NZ_CP055001 Location: 1..132056 Organism: Shigella flexneri strain STIN_80 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ55_RS23515 (1) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| HUZ55_RS23520 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| HUZ55_RS23525 (2124) | 2124..2319 | - | 196 | Protein_2 | serine/threonine protein kinase | - |
| HUZ55_RS23530 (2406) | 2406..2816 | - | 411 | Protein_3 | IS3 family transposase ISEhe3 | Transposase |
| HUZ55_RS23535 (2879) | 2879..3583 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ55_RS23540 (3637) | 3637..4104 | + | 468 | Protein_5 | conjugal transfer protein | - |
| HUZ55_RS23545 (4349) | 4349..4465 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| HUZ55_RS23550 (4481) | 4481..6400 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| HUZ55_RS23555 (6519) | 6519..6686 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| HUZ55_RS23560 (6947) | 6947..7579 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| HUZ55_RS23565 (7826) | 7826..8158 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| HUZ55_RS23570 (8281) | 8281..9119 | - | 839 | Protein_11 | Streptomycin 3''-adenylyltransferase | ARG |
| HUZ55_RS23575 (9212) | 9212..10471 | - | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| HUZ55_RS23580 (10686) | 10686..11524 | - | 839 | Protein_13 | Streptomycin 3''-adenylyltransferase | ARG |
| HUZ55_RS23585 (11530) | 11530..11820 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HUZ55_RS23590 (11932) | 11932..12429 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| HUZ55_RS23595 (12574) | 12574..13587 | + | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| HUZ55_RS23600 (13790) | 13790..14140 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| HUZ55_RS23605 (14266) | 14266..14826 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HUZ55_RS23610 (14829) | 14829..17780 | + | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| HUZ55_RS23615 (17714) | 17714..18190 | + | 477 | WP_223171565.1 | hypothetical protein | - |
| HUZ55_RS23620 (18275) | 18275..18979 | - | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| HUZ55_RS23625 (19043) | 19043..19873 | + | 831 | Protein_22 | IS91 family transposase ISVsa3 | Transposase |
| HUZ55_RS23630 (19904) | 19904..20788 | + | 885 | WP_012728215.1 | DUF3363 domain-containing protein | - |
| HUZ55_RS23635 (21005) | 21005..22219 | + | 1215 | WP_058657119.1 | Bicyclomycin resistance protein | ARG |
| HUZ55_RS23640 (22247) | 22247..22552 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| HUZ55_RS23645 (22664) | 22664..24157 | + | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| HUZ55_RS23650 (24393) | 24393..24635 | - | 243 | Protein_27 | phosphoglucosamine mutase | - |
| HUZ55_RS23655 (24722) | 24722..25537 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| HUZ55_RS23660 (25627) | 25627..26717 | + | 1091 | WP_085940648.1 | IS4 family transposase ISAba1 | Transposase |
| HUZ55_RS23665 (26914) | 26914..27201 | - | 288 | WP_230071785.1 | hypothetical protein | - |
| HUZ55_RS23670 (27449) | 27449..28153 | - | 705 | Protein_31 | IS6 family transposase IS26 | Transposase |
| HUZ55_RS23675 (28219) | 28219..29733 | + | 1515 | Protein_32 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ55_RS23680 (29791) | 29791..30033 | + | 243 | WP_000844627.1 | transposase | - |
| HUZ55_RS23685 (30065) | 30065..30715 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HUZ55_RS23690 (30821) | 30821..32020 | + | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| HUZ55_RS23695 (32052) | 32052..32936 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| HUZ55_RS23700 (33074) | 33074..33508 | - | 435 | WP_223963367.1 | isochorismatase family cysteine hydrolase | - |
| HUZ55_RS23705 (33471) | 33471..35132 | + | 1662 | Protein_38 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ55_RS23710 (35234) | 35234..35491 | + | 258 | WP_231363335.1 | hypothetical protein | - |
| HUZ55_RS23715 (35600) | 35600..36304 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ55_RS23720 (36494) | 36494..37309 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HUZ55_RS23725 (37460) | 37460..38164 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ55_RS23730 (38216) | 38216..38467 | + | 252 | Protein_43 | hypothetical protein | - |
| HUZ55_RS23735 (38613) | 38613..39476 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| HUZ55_RS23740 (39514) | 39514..39759 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| HUZ55_RS23745 (40228) | 40228..41019 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| HUZ55_RS23750 (41277) | 41277..42137 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HUZ55_RS23755 (42320) | 42320..42877 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HUZ55_RS23760 (43169) | 43169..43873 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ55_RS23765 (44026) | 44026..44847 | - | 822 | WP_000939727.1 | hypothetical protein | ARG |
| HUZ55_RS23770 (44932) | 44932..45770 | - | 839 | Protein_51 | Streptomycin 3''-adenylyltransferase | ARG |
| HUZ55_RS23775 (45919) | 45919..46716 | + | 798 | Protein_52 | IS91 family transposase ISMno23 | Transposase |
| HUZ55_RS23780 (46769) | 46769..47473 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUZ55_RS23785 (48010) | 48010..48552 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| HUZ55_RS23790 (48565) | 48565..49425 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| HUZ55_RS23795 (49568) | 49568..50062 | + | 495 | Protein_56 | IS4 family transposase IS10R | Transposase |
| HUZ55_RS23800 (50116) | 50116..50820 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HUZ55_RS23805 (50888) | 50888..52186 | + | 1299 | Protein_58 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ55_RS23810 (52220) | 52220..52720 | + | 501 | Protein_59 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ55_RS23815 (52754) | 52754..52942 | + | 189 | Protein_60 | IS3 family transposase | - |
| HUZ55_RS23820 (53017) | 53017..53304 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HUZ55_RS23825 (53301) | 53301..53552 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| HUZ55_RS23830 (54518) | 54518..55375 | - | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| HUZ55_RS23835 (55368) | 55368..55442 | - | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| HUZ55_RS23840 (55674) | 55674..55931 | - | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| HUZ55_RS23845 (56199) | 56199..56348 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (56392) | 56392..56453 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| HUZ55_RS23850 (56795) | 56795..57007 | - | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| HUZ55_RS23855 (57142) | 57142..57702 | - | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| HUZ55_RS23860 (57757) | 57757..58500 | - | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| HUZ55_RS23865 (58520) | 58520..63790 | - | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| HUZ55_RS23870 (63790) | 63790..65979 | - | 2190 | WP_039002212.1 | type IV conjugative transfer system coupling protein TraD | - |
| HUZ55_RS23875 (66232) | 66232..66963 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| HUZ55_RS23880 (66995) | 66995..67498 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| HUZ55_RS23885 (67513) | 67513..70335 | - | 2823 | WP_239592431.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HUZ55_RS23890 (70332) | 70332..71705 | - | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| HUZ55_RS23895 (71705) | 71705..72067 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| HUZ55_RS23900 (71997) | 71997..72542 | - | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HUZ55_RS23905 (72529) | 72529..72765 | - | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HUZ55_RS23910 (72926) | 72926..73669 | - | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HUZ55_RS23915 (73662) | 73662..73922 | - | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| HUZ55_RS23920 (73949) | 73949..75757 | - | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HUZ55_RS23925 (75754) | 75754..76392 | - | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HUZ55_RS23930 (76401) | 76401..77393 | - | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| HUZ55_RS23935 (77390) | 77390..78022 | - | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| HUZ55_RS23940 (78019) | 78019..78405 | - | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| HUZ55_RS23945 (78402) | 78402..81029 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| HUZ55_RS23950 (81189) | 81189..81410 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| HUZ55_RS23955 (81545) | 81545..82060 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HUZ55_RS23960 (82057) | 82057..82377 | - | 321 | WP_063078087.1 | conjugal transfer protein TrbD | - |
| HUZ55_RS23965 (82364) | 82364..82951 | - | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| HUZ55_RS23970 (82941) | 82941..84368 | - | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| HUZ55_RS23975 (84368) | 84368..85096 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| HUZ55_RS23980 (85083) | 85083..85649 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| HUZ55_RS23985 (85671) | 85671..85982 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HUZ55_RS23990 (85987) | 85987..86349 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| HUZ55_RS23995 (86382) | 86382..86783 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| HUZ55_RS24000 (86876) | 86876..87565 | - | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| HUZ55_RS24005 (87752) | 87752..88135 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| HUZ55_RS24010 (88456) | 88456..89058 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| HUZ55_RS24015 (89355) | 89355..90176 | - | 822 | WP_072795862.1 | DUF932 domain-containing protein | - |
| HUZ55_RS24020 (90298) | 90298..90585 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| HUZ55_RS24025 (90610) | 90610..90816 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| HUZ55_RS24030 (90886) | 90886..91059 | + | 174 | Protein_103 | hypothetical protein | - |
| HUZ55_RS24035 (91057) | 91057..91287 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| HUZ55_RS24040 (91507) | 91507..91632 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUZ55_RS24045 (91574) | 91574..91723 | - | 150 | Protein_106 | plasmid maintenance protein Mok | - |
| - (91709) | 91709..91933 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (91709) | 91709..91933 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (91709) | 91709..91933 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (91709) | 91709..91933 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| HUZ55_RS24050 (91745) | 91745..91933 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| HUZ55_RS24055 (91945) | 91945..92664 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| HUZ55_RS24060 (92661) | 92661..93095 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| HUZ55_RS24065 (93150) | 93150..95108 | - | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| HUZ55_RS24070 (95173) | 95173..95406 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| HUZ55_RS24075 (95463) | 95463..96002 | - | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| HUZ55_RS24080 (96028) | 96028..96234 | - | 207 | WP_000275853.1 | hypothetical protein | - |
| HUZ55_RS24085 (96475) | 96475..96702 | - | 228 | WP_071961421.1 | hypothetical protein | - |
| HUZ55_RS24090 (96854) | 96854..97417 | - | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| HUZ55_RS24095 (97465) | 97465..98826 | - | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| HUZ55_RS24100 (98878) | 98878..99108 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| HUZ55_RS24105 (99774) | 99774..99929 | - | 156 | WP_001744062.1 | hypothetical protein | - |
| HUZ55_RS24110 (100143) | 100143..100334 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| HUZ55_RS24115 (100331) | 100331..100753 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| HUZ55_RS24120 (100800) | 100800..101225 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| HUZ55_RS24125 (101642) | 101642..102418 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| HUZ55_RS24130 (102469) | 102469..102987 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| HUZ55_RS24135 (102917) | 102917..103138 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| HUZ55_RS24140 (103139) | 103139..103822 | - | 684 | WP_000086185.1 | DNA methylase | - |
| HUZ55_RS24145 (103899) | 103899..104210 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| HUZ55_RS24150 (104207) | 104207..105109 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HUZ55_RS24155 (105527) | 105527..105775 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| HUZ55_RS24160 (105772) | 105772..106209 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HUZ55_RS24165 (106209) | 106209..107480 | + | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| HUZ55_RS24170 (107485) | 107485..107877 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| HUZ55_RS24175 (107882) | 107882..108853 | - | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| HUZ55_RS24180 (109075) | 109075..109719 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| HUZ55_RS24185 (109713) | 109713..109988 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| HUZ55_RS24190 (110140) | 110140..110916 | - | 777 | Protein_135 | site-specific integrase | - |
| HUZ55_RS24195 (110913) | 110913..111419 | - | 507 | WP_001505085.1 | hypothetical protein | - |
| HUZ55_RS24200 (111410) | 111410..112114 | + | 705 | WP_065304467.1 | IS6 family transposase IS26 | Transposase |
| HUZ55_RS24205 (112263) | 112263..113588 | - | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| HUZ55_RS24210 (113698) | 113698..114395 | + | 698 | WP_114161604.1 | IS1 family transposase IS1R | Transposase |
| HUZ55_RS24215 (114496) | 114496..114777 | - | 282 | WP_000639434.1 | hypothetical protein | - |
| HUZ55_RS24220 (114879) | 114879..115772 | - | 894 | Protein_141 | IS3 family transposase ISEhe3 | Transposase |
| HUZ55_RS24225 (115840) | 115840..116658 | + | 819 | Protein_142 | IS30 family transposase IS30D | Transposase |
| HUZ55_RS24235 (117993) | 117993..118142 | + | 150 | Protein_144 | IS30 family transposase IS30D | Transposase |
| HUZ55_RS24240 (118567) | 118567..118851 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| HUZ55_RS24245 (118871) | 118871..120004 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| HUZ55_RS24250 (120267) | 120267..121904 | - | 1638 | WP_223201785.1 | hypothetical protein | - |
| HUZ55_RS24255 (121955) | 121955..122785 | - | 831 | WP_223201786.1 | hypothetical protein | - |
| HUZ55_RS24260 (122837) | 122837..123385 | - | 549 | WP_039002808.1 | hypothetical protein | - |
| HUZ55_RS24265 (123691) | 123691..123921 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| HUZ55_RS24270 (123918) | 123918..124334 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HUZ55_RS24275 (124496) | 124496..126634 | - | 2139 | WP_039002805.1 | AAA family ATPase | - |
| HUZ55_RS24280 (127099) | 127099..128094 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| HUZ55_RS24285 (128137) | 128137..129030 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| HUZ55_RS24295 (130012) | 130012..130170 | + | 159 | WP_228955855.1 | abortive infection family protein | - |
| HUZ55_RS24300 (130329) | 130329..131301 | - | 973 | Protein_157 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|