MGE detailed information
MGE type: Conjugative plasmid MGE length: 124795 bp
Accession: NZ_CP054980 Location: 1..124795 Organism: Shigella flexneri strain STIN_92 Replicon: plasmid unnamed3
Accession: NZ_CP054980 Location: 1..124795 Organism: Shigella flexneri strain STIN_92 Replicon: plasmid unnamed3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ60_RS25330 (1) | 1..858 | + | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| HUZ60_RS25335 (1824) | 1824..2075 | + | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| HUZ60_RS25340 (2072) | 2072..2359 | + | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HUZ60_RS25345 (2434) | 2434..2622 | - | 189 | Protein_3 | IS3 family transposase | - |
| HUZ60_RS25350 (2656) | 2656..3156 | - | 501 | Protein_4 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ60_RS25355 (3190) | 3190..6195 | - | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUZ60_RS25360 (6359) | 6359..6916 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HUZ60_RS25365 (7099) | 7099..7959 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HUZ60_RS25370 (8106) | 8106..9019 | - | 914 | Protein_8 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUZ60_RS25375 (9224) | 9224..9445 | - | 222 | Protein_9 | tyrosine-type recombinase/integrase | - |
| HUZ60_RS25380 (9511) | 9511..10215 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HUZ60_RS25385 (10268) | 10268..10447 | - | 180 | Protein_11 | EAL domain-containing protein | - |
| HUZ60_RS25390 (10650) | 10650..11663 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| HUZ60_RS25395 (11808) | 11808..12305 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| HUZ60_RS25400 (12417) | 12417..12707 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HUZ60_RS25405 (12713) | 12713..13551 | + | 839 | Protein_15 | Streptomycin 3''-adenylyltransferase | ARG |
| HUZ60_RS25410 (13766) | 13766..15025 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| HUZ60_RS25415 (15118) | 15118..15956 | + | 839 | Protein_17 | Streptomycin 3''-adenylyltransferase | ARG |
| HUZ60_RS25420 (16079) | 16079..16411 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| HUZ60_RS25425 (16658) | 16658..17290 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| HUZ60_RS25430 (17313) | 17313..17543 | + | 231 | WP_136655701.1 | hypothetical protein | - |
| HUZ60_RS25435 (17551) | 17551..17718 | - | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| HUZ60_RS25440 (17837) | 17837..19756 | - | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| HUZ60_RS25445 (19772) | 19772..19888 | - | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| HUZ60_RS25450 (20133) | 20133..20600 | - | 468 | Protein_24 | conjugal transfer protein | - |
| HUZ60_RS25455 (20654) | 20654..21358 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HUZ60_RS25460 (21426) | 21426..22370 | + | 945 | Protein_26 | IS110 family transposase IS5708 | Transposase |
| HUZ60_RS25465 (22778) | 22778..23131 | + | 354 | Protein_27 | RNA 3'-terminal phosphate cyclase | - |
| HUZ60_RS25470 (23174) | 23174..25879 | - | 2706 | WP_239636846.1 | HTH-type transcriptional regulator MalT | VF |
| HUZ60_RS25475 (26208) | 26208..26905 | + | 698 | WP_223419864.1 | IS1 family transposase IS1R | Transposase |
| HUZ60_RS25480 (26915) | 26915..27646 | + | 732 | WP_094336930.1 | Murein DD-endopeptidase MepM | VF |
| HUZ60_RS25485 (27680) | 27680..27877 | - | 198 | WP_000843496.1 | DUF2933 domain-containing protein | - |
| HUZ60_RS25490 (27918) | 27918..30395 | - | 2478 | WP_001398208.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HUZ60_RS25495 (30492) | 30492..30932 | - | 441 | WP_000758221.1 | DUF411 domain-containing protein | - |
| HUZ60_RS25500 (31019) | 31019..34165 | - | 3147 | WP_000574035.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HUZ60_RS25505 (34176) | 34176..35468 | - | 1293 | WP_080052003.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HUZ60_RS25510 (35582) | 35582..35935 | - | 354 | WP_001246155.1 | cation efflux system protein CusF | - |
| HUZ60_RS25515 (35963) | 35963..37348 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| HUZ60_RS25520 (37538) | 37538..38218 | + | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| HUZ60_RS25525 (38211) | 38211..39686 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| HUZ60_RS25530 (39937) | 39937..40368 | + | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| HUZ60_RS25535 (40512) | 40512..40862 | + | 351 | WP_000694953.1 | DUF305 domain-containing protein | - |
| HUZ60_RS25540 (41250) | 41250..42158 | - | 909 | Protein_42 | HNH endonuclease | - |
| HUZ60_RS25545 (42795) | 42795..43769 | + | 975 | WP_001148756.1 | sensor domain-containing diguanylate cyclase | - |
| HUZ60_RS25550 (44337) | 44337..44687 | + | 351 | WP_004118279.1 | hypothetical protein | - |
| HUZ60_RS25555 (44738) | 44738..45481 | + | 744 | WP_000129823.1 | hypothetical protein | - |
| HUZ60_RS25560 (45478) | 45478..46254 | + | 777 | WP_000015958.1 | site-specific integrase | - |
| HUZ60_RS25565 (46312) | 46312..46569 | - | 258 | WP_000764642.1 | hypothetical protein | - |
| HUZ60_RS25570 (46698) | 46698..46802 | - | 105 | WP_032409716.1 | hypothetical protein | - |
| HUZ60_RS25575 (47337) | 47337..48203 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| HUZ60_RS25580 (48524) | 48524..48793 | - | 270 | WP_000339857.1 | hypothetical protein | - |
| HUZ60_RS25585 (49208) | 49208..50413 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| HUZ60_RS25590 (50413) | 50413..51387 | + | 975 | WP_000064120.1 | ParB family protein | - |
| HUZ60_RS25595 (51469) | 51469..52176 | - | 708 | Protein_53 | translesion error-prone DNA polymerase V subunit UmuC | - |
| HUZ60_RS25600 (52619) | 52619..53587 | + | 969 | WP_162722054.1 | IS5 family transposase IS903B | Transposase |
| HUZ60_RS25605 (53727) | 53727..54113 | - | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| HUZ60_RS25610 (54188) | 54188..54892 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HUZ60_RS25615 (55444) | 55444..55653 | + | 210 | Protein_57 | hypothetical protein | - |
| HUZ60_RS25620 (55778) | 55778..56692 | - | 915 | Protein_58 | IS5 family transposase ISKpn26 | Transposase |
| HUZ60_RS25625 (57055) | 57055..58026 | - | 972 | WP_032482493.1 | IS91 family transposase ISAzo26 | Transposase |
| HUZ60_RS25630 (58429) | 58429..59061 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| HUZ60_RS25635 (59084) | 59084..59359 | + | 276 | WP_109023896.1 | hypothetical protein | - |
| HUZ60_RS25640 (59362) | 59362..60153 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| HUZ60_RS25645 (60622) | 60622..60867 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| HUZ60_RS25650 (60905) | 60905..61768 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| HUZ60_RS25655 (61914) | 61914..62171 | - | 258 | Protein_65 | hypothetical protein | - |
| HUZ60_RS25660 (62226) | 62226..62930 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| HUZ60_RS25665 (62996) | 62996..63478 | + | 483 | Protein_67 | IS3 family transposase | - |
| HUZ60_RS25670 (63521) | 63521..64339 | - | 819 | Protein_68 | IS30 family transposase IS30D | Transposase |
| HUZ60_RS25675 (64407) | 64407..65300 | + | 894 | Protein_69 | IS3 family transposase ISEhe3 | Transposase |
| HUZ60_RS25680 (65402) | 65402..65683 | + | 282 | WP_000639434.1 | hypothetical protein | - |
| HUZ60_RS25690 (66591) | 66591..67916 | + | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| HUZ60_RS25695 (68065) | 68065..68769 | - | 705 | WP_239636843.1 | IS6-like element IS26 family transposase | - |
| HUZ60_RS25700 (68760) | 68760..69266 | + | 507 | WP_001505085.1 | hypothetical protein | - |
| HUZ60_RS25705 (69263) | 69263..70039 | + | 777 | Protein_75 | site-specific integrase | - |
| HUZ60_RS25710 (70191) | 70191..70466 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| HUZ60_RS25715 (70460) | 70460..71104 | - | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| HUZ60_RS25720 (71326) | 71326..72297 | + | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| HUZ60_RS25725 (72302) | 72302..72694 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| HUZ60_RS25730 (72699) | 72699..73970 | - | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| HUZ60_RS25735 (73970) | 73970..74407 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HUZ60_RS25740 (74404) | 74404..74652 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| HUZ60_RS25745 (75070) | 75070..75972 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HUZ60_RS25750 (75969) | 75969..76280 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| HUZ60_RS25755 (76357) | 76357..77040 | + | 684 | WP_000086185.1 | DNA methylase | - |
| HUZ60_RS25760 (77041) | 77041..77262 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| HUZ60_RS25765 (77192) | 77192..77710 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| HUZ60_RS25770 (77761) | 77761..78537 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| HUZ60_RS25775 (78954) | 78954..79379 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| HUZ60_RS25780 (79426) | 79426..79848 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| HUZ60_RS25785 (79845) | 79845..80036 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| HUZ60_RS25790 (81071) | 81071..81301 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| HUZ60_RS25795 (81353) | 81353..82714 | + | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| HUZ60_RS25800 (82762) | 82762..83325 | + | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| HUZ60_RS25805 (83477) | 83477..83704 | + | 228 | WP_071961421.1 | hypothetical protein | - |
| HUZ60_RS25810 (83697) | 83697..84032 | + | 336 | WP_014106969.1 | hypothetical protein | - |
| HUZ60_RS25815 (83945) | 83945..84151 | + | 207 | WP_000275853.1 | hypothetical protein | - |
| HUZ60_RS25820 (84177) | 84177..84716 | + | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| HUZ60_RS25825 (84773) | 84773..85006 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| HUZ60_RS25830 (85071) | 85071..87029 | + | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| HUZ60_RS25835 (87084) | 87084..87518 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| HUZ60_RS25840 (87515) | 87515..88234 | + | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| HUZ60_RS25845 (88246) | 88246..88434 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (88246) | 88246..88470 | + | 225 | NuclAT_0 | - | - |
| - (88246) | 88246..88470 | + | 225 | NuclAT_0 | - | - |
| - (88246) | 88246..88470 | + | 225 | NuclAT_0 | - | - |
| - (88246) | 88246..88470 | + | 225 | NuclAT_0 | - | - |
| HUZ60_RS25850 (88456) | 88456..88605 | + | 150 | Protein_104 | plasmid maintenance protein Mok | - |
| HUZ60_RS25855 (88547) | 88547..88672 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUZ60_RS25860 (88892) | 88892..89122 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| HUZ60_RS25865 (89120) | 89120..89293 | - | 174 | Protein_107 | hypothetical protein | - |
| HUZ60_RS25870 (89363) | 89363..89569 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| HUZ60_RS25875 (89594) | 89594..89881 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| HUZ60_RS25880 (90004) | 90004..90825 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| HUZ60_RS25885 (91122) | 91122..91724 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| HUZ60_RS25890 (92045) | 92045..92428 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| HUZ60_RS25895 (92615) | 92615..93304 | + | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| HUZ60_RS25900 (93397) | 93397..93798 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| HUZ60_RS25905 (93831) | 93831..94193 | + | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| HUZ60_RS25910 (94198) | 94198..94509 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| HUZ60_RS25915 (94531) | 94531..95097 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| HUZ60_RS25920 (95084) | 95084..95812 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| HUZ60_RS25925 (95812) | 95812..97239 | + | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| HUZ60_RS25930 (97229) | 97229..97816 | + | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| HUZ60_RS25935 (97803) | 97803..98123 | + | 321 | WP_239606302.1 | conjugal transfer protein TrbD | - |
| HUZ60_RS25940 (98120) | 98120..98635 | + | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HUZ60_RS25945 (98770) | 98770..98991 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| HUZ60_RS25950 (99151) | 99151..101778 | + | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| HUZ60_RS25955 (101775) | 101775..102161 | + | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| HUZ60_RS25960 (102158) | 102158..102790 | + | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| HUZ60_RS25965 (102787) | 102787..103779 | + | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| HUZ60_RS25970 (103788) | 103788..104426 | + | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HUZ60_RS25975 (104423) | 104423..106231 | + | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HUZ60_RS25980 (106258) | 106258..106518 | + | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| HUZ60_RS25985 (106511) | 106511..107254 | + | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HUZ60_RS25990 (107415) | 107415..107651 | + | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HUZ60_RS25995 (107638) | 107638..108183 | + | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HUZ60_RS26000 (108113) | 108113..108475 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| HUZ60_RS26005 (108475) | 108475..109848 | + | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| HUZ60_RS26010 (109845) | 109845..112667 | + | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HUZ60_RS26015 (112682) | 112682..113185 | + | 504 | WP_000605510.1 | hypothetical protein | - |
| HUZ60_RS26020 (113217) | 113217..113948 | + | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| HUZ60_RS26025 (114201) | 114201..116381 | + | 2181 | WP_063078088.1 | type IV conjugative transfer system coupling protein TraD | - |
| HUZ60_RS26030 (116381) | 116381..121651 | + | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| HUZ60_RS26035 (121671) | 121671..122414 | + | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| HUZ60_RS26040 (122469) | 122469..123029 | + | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| HUZ60_RS26045 (123164) | 123164..123376 | + | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| - (123718) | 123718..123779 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (123718) | 123718..123779 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (123718) | 123718..123779 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (123718) | 123718..123779 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| HUZ60_RS26050 (123823) | 123823..123972 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| HUZ60_RS26055 (124240) | 124240..124497 | + | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| HUZ60_RS26060 (124600) | 124600..124783 | + | 184 | Protein_146 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|