MGE detailed information
MGE type: Conjugative plasmid MGE length: 131660 bp
Accession: NZ_CP054237 Location: 1..131660 Organism: Escherichia coli strain EcPF5 Replicon: plasmid p1
Accession: NZ_CP054237 Location: 1..131660 Organism: Escherichia coli strain EcPF5 Replicon: plasmid p1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HR070_RS24525 () | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| HR070_RS24530 () | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| HR070_RS24535 () | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| HR070_RS24540 () | 2649..2956 | - | 308 | Protein_3 | type II toxin-antitoxin system ParD family antitoxin | - |
| HR070_RS24545 () | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| HR070_RS24550 () | 4651..4779 | + | 129 | Protein_5 | IS481 family transposase | - |
| HR070_RS24555 () | 4814..5107 | - | 294 | WP_001105060.1 | hypothetical protein | - |
| HR070_RS24560 () | 5213..5488 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HR070_RS24565 () | 5488..5772 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| HR070_RS24570 () | 6377..7129 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| HR070_RS24575 () | 7175..8140 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| HR070_RS24580 () | 8173..8553 | - | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| HR070_RS24585 () | 8578..9468 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| HR070_RS24590 () | 9701..9895 | - | 195 | WP_000796505.1 | hypothetical protein | - |
| HR070_RS24595 () | 9869..10309 | + | 441 | Protein_14 | zinc-binding dehydrogenase | - |
| HR070_RS24600 () | 10440..11318 | + | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| HR070_RS24605 () | 11308..12195 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| HR070_RS24610 () | 12206..13030 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| HR070_RS24615 () | 13036..14109 | + | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| HR070_RS24620 () | 14102..15412 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| HR070_RS24625 () | 15471..15779 | - | 309 | Protein_20 | IS4 family transposase ISEc13 | Transposase |
| HR070_RS24630 () | 15856..16089 | - | 234 | Protein_21 | Tn3 family transposase ISPsy39 | Transposase |
| HR070_RS24635 () | 16111..16585 | - | 475 | Protein_22 | IS3 family transposase IS629 | Transposase |
| HR070_RS24640 () | 16675..18183 | - | 1509 | WP_001189123.1 | group II intron reverse transcriptase/maturase | - |
| HR070_RS24645 () | 18856..19577 | - | 722 | Protein_24 | IS3 family transposase IS629 | Transposase |
| HR070_RS24650 () | 19602..20306 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| HR070_RS24655 () | 20364..20894 | - | 531 | Protein_26 | histidine-type phosphatase | - |
| HR070_RS24660 () | 21016..21501 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| HR070_RS24665 () | 21526..22011 | - | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| HR070_RS24670 () | 21998..22693 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| HR070_RS24675 () | 22698..23828 | - | 1131 | WP_000729220.1 | ABC transporter permease | - |
| HR070_RS24680 () | 23818..25101 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| HR070_RS24685 () | 25104..26483 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| HR070_RS24690 () | 26587..27114 | - | 528 | WP_000178050.1 | iron transporter | - |
| HR070_RS24695 () | 27155..29041 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| HR070_RS24700 () | 29388..30203 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| HR070_RS24705 () | 30386..30892 | - | 507 | WP_042068957.1 | protein disulfide oxidoreductase | - |
| HR070_RS24710 () | 30940..31644 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HR070_RS24715 () | 31708..32046 | + | 339 | Protein_38 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HR070_RS24720 () | 32229..33089 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HR070_RS24725 () | 33239..33517 | + | 279 | Protein_40 | IS91 family transposase ISPps1 | Transposase |
| HR070_RS24730 () | 33687..34391 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HR070_RS24735 () | 34441..35160 | + | 720 | Protein_42 | AAA family ATPase | - |
| HR070_RS24740 () | 35147..35998 | + | 852 | WP_000240536.1 | replication protein | - |
| HR070_RS24745 () | 36306..37121 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| HR070_RS24750 () | 37182..37985 | + | 804 | WP_024261901.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HR070_RS24755 () | 37985..38821 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| HR070_RS24760 () | 38928..39191 | - | 264 | Protein_47 | transposase zinc-binding domain-containing protein | - |
| HR070_RS24765 () | 39239..39943 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HR070_RS24770 () | 40008..40298 | - | 291 | Protein_49 | class 1 integron integrase IntI1 | - |
| HR070_RS24775 () | 40455..40928 | + | 474 | WP_000777555.1 | Dihydrofolate reductase type 1 | ARG |
| HR070_RS24780 () | 41021..41812 | + | 792 | WP_001206317.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HR070_RS24785 () | 41976..42323 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| HR070_RS24790 () | 42317..43156 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| HR070_RS24795 () | 43284..43784 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| HR070_RS24800 () | 43890..44342 | - | 453 | Protein_55 | TniB family NTP-binding protein | - |
| HR070_RS24805 () | 44345..46024 | - | 1680 | WP_000179844.1 | DDE-type integrase/transposase/recombinase | - |
| HR070_RS24810 () | 46099..46767 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| HR070_RS24815 () | 46803..47039 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| HR070_RS24820 () | 47036..47398 | - | 363 | WP_001277457.1 | mercury resistance co-regulator MerD | - |
| HR070_RS24825 () | 47416..49110 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| HR070_RS24830 () | 49162..49584 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| HR070_RS24835 () | 49620..49895 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| HR070_RS24840 () | 49909..50259 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| HR070_RS24845 () | 50331..50765 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| HR070_RS24850 () | 50872..51569 | - | 698 | Protein_65 | IS1 family transposase IS1R | Transposase |
| HR070_RS24855 () | 51972..52373 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HR070_RS24860 () | 52306..52563 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HR070_RS24865 () | 52656..53309 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HR070_RS24870 () | 53407..53547 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| HR070_RS24875 () | 54249..55106 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| HR070_RS24880 () | 55099..55173 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| HR070_RS24885 () | 55410..55562 | - | 153 | Protein_72 | replication protein A | - |
| HR070_RS24890 () | 55756..57297 | + | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| HR070_RS24895 () | 57312..58058 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| HR070_RS24900 () | 58128..58250 | - | 123 | Protein_75 | hypothetical protein | - |
| HR070_RS24905 () | 58547..58681 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 58726..58786 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 58726..58786 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 58726..58786 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 58726..58786 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| HR070_RS24910 () | 58753..59039 | - | 287 | Protein_77 | DUF2726 domain-containing protein | - |
| HR070_RS24915 () | 59552..59764 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| HR070_RS24920 () | 59895..60455 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| HR070_RS24925 () | 60510..61256 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| HR070_RS24930 () | 61276..66546 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| HR070_RS24935 () | 66546..68735 | - | 2190 | WP_024946705.1 | type IV conjugative transfer system coupling protein TraD | - |
| HR070_RS24940 () | 68732..69511 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| HR070_RS24945 () | 69714..70445 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| HR070_RS24950 () | 70477..70974 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| HR070_RS24955 () | 70993..73812 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| HR070_RS24960 () | 73809..75182 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| HR070_RS24965 () | 75169..75594 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| HR070_RS24970 () | 75542..75889 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| HR070_RS24975 () | 75819..76364 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HR070_RS24980 () | 76351..76635 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HR070_RS24985 () | 76762..77082 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| HR070_RS24990 () | 77130..77827 | - | 698 | Protein_93 | IS1 family transposase IS1G | Transposase |
| HR070_RS24995 () | 77926..78153 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| HR070_RS25000 () | 78241..78918 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| HR070_RS25005 () | 79052..79435 | - | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| HR070_RS25010 () | 79766..80368 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| HR070_RS25015 () | 80665..81486 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| HR070_RS25020 () | 81605..81892 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| HR070_RS25025 () | 81917..82123 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| HR070_RS25030 () | 82036..82371 | - | 336 | WP_013023876.1 | hypothetical protein | - |
| HR070_RS25035 () | 82814..82972 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 83016..83143 | - | 128 | NuclAT_0 | - | Antitoxin Detail |
| - () | 83016..83143 | - | 128 | NuclAT_0 | - | Antitoxin Detail |
| - () | 83016..83143 | - | 128 | NuclAT_0 | - | Antitoxin Detail |
| - () | 83016..83143 | - | 128 | NuclAT_0 | - | Antitoxin Detail |
| - () | 84585..84687 | - | 103 | NuclAT_1 | - | - |
| - () | 84585..84687 | - | 103 | NuclAT_1 | - | - |
| - () | 84585..84687 | - | 103 | NuclAT_1 | - | - |
| - () | 84585..84687 | - | 103 | NuclAT_1 | - | - |
| HR070_RS25045 () | 84699..85418 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| HR070_RS25050 () | 85415..85849 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| HR070_RS25055 () | 85904..87862 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| HR070_RS25060 () | 87928..88161 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| HR070_RS25065 () | 88224..88763 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| HR070_RS25070 () | 88908..89243 | - | 336 | WP_013023883.1 | hypothetical protein | - |
| HR070_RS25075 () | 89406..89624 | - | 219 | WP_001496291.1 | hypothetical protein | - |
| HR070_RS25080 () | 89650..90213 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| HR070_RS25085 () | 90261..91622 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| HR070_RS25090 () | 91674..91904 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| HR070_RS25095 () | 92939..93130 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| HR070_RS25100 () | 93127..93549 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| HR070_RS25105 () | 93596..93898 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| HR070_RS25110 () | 94438..95214 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| HR070_RS25115 () | 95265..95699 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| HR070_RS25120 () | 95713..95934 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| HR070_RS25125 () | 95935..96618 | - | 684 | WP_000086185.1 | DNA methylase | - |
| HR070_RS25130 () | 96695..96999 | - | 305 | Protein_121 | hypothetical protein | - |
| HR070_RS25135 () | 97003..97905 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HR070_RS25140 () | 98772..99743 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HR070_RS25145 () | 99743..100909 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| HR070_RS25150 () | 101497..102252 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| HR070_RS25155 () | 103026..103832 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| HR070_RS25160 () | 103833..104138 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| HR070_RS25165 () | 104140..104358 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| HR070_RS25170 () | 104992..105189 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| HR070_RS25175 () | 105186..105470 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| HR070_RS25180 () | 105490..106623 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| HR070_RS25185 () | 106886..110005 | - | 3120 | WP_001553851.1 | hypothetical protein | - |
| HR070_RS25190 () | 110312..110542 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| HR070_RS25195 () | 110539..110955 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HR070_RS25200 () | 111117..113255 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| HR070_RS25205 () | 113720..114715 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| HR070_RS25210 () | 114719..115651 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| HR070_RS25215 () | 115788..116485 | - | 698 | Protein_138 | IS1 family transposase IS1G | Transposase |
| HR070_RS25220 () | 116699..119815 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| HR070_RS25225 () | 119937..121220 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| HR070_RS25230 () | 121217..122773 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| HR070_RS25235 () | 122956..123177 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| HR070_RS25240 () | 123177..123557 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| HR070_RS25245 () | 123562..123741 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| HR070_RS25250 () | 123769..124128 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| HR070_RS25255 () | 124052..124465 | + | 414 | Protein_146 | IS3 family transposase ISLad1 | Transposase |
| HR070_RS25260 () | 124415..124732 | - | 318 | WP_001513659.1 | hypothetical protein | - |
| HR070_RS25265 () | 124960..125976 | - | 1017 | WP_012372828.1 | IS5 family transposase IS5D | Transposase |
| HR070_RS25270 () | 126184..127587 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| HR070_RS25275 () | 127574..128506 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| HR070_RS25280 () | 128615..128944 | - | 330 | Protein_151 | TOBE domain-containing protein | - |
| HR070_RS25285 () | 128960..129657 | - | 698 | Protein_152 | IS1 family transposase IS1R | Transposase |
| HR070_RS25290 () | 130144..130875 | - | 732 | WP_001617898.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|