NZ_CP0541661..165243

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 165243 bp
Accession: NZ_CP054166        Location: 1..165243         Organism: Escherichia coli strain STO_Bone1B       Replicon: plasmid pBone1BIncF


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRS04_RS00010 (1069) 1069..1509 + 441 Protein_1 zinc-binding dehydrogenase -
HRS04_RS00015 (1640) 1640..2518 + 879 WP_000338039.1 sugar ABC transporter permease -
HRS04_RS00020 (2508) 2508..3395 + 888 WP_001271561.1 carbohydrate ABC transporter permease -
HRS04_RS00025 (3406) 3406..4230 + 825 WP_000922702.1 phosphodiesterase -
HRS04_RS00030 (4236) 4236..5309 + 1074 WP_033549814.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
HRS04_RS00035 (5302) 5302..6612 + 1311 WP_000476108.1 ABC transporter substrate-binding protein -
HRS04_RS00040 (6671) 6671..6979 - 309 Protein_7 IS4 family transposase ISEc13 Transposase
HRS04_RS00045 (7056) 7056..7229 - 174 WP_000338295.1 Tn3 family transposase ISPsy39 Transposase
HRS04_RS00050 (7311) 7311..7791 - 481 Protein_9 IS3 family transposase IS629 Transposase
HRS04_RS00055 (7875) 7875..9383 - 1509 WP_001189123.1 group II intron reverse transcriptase/maturase -
HRS04_RS00060 (10056) 10056..10777 - 722 Protein_11 IS3 family transposase IS629 Transposase
HRS04_RS00065 (10802) 10802..11506 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
HRS04_RS00070 (11559) 11559..12410 - 852 Protein_13 IS4 family transposase IS10R Transposase
HRS04_RS00075 (12501) 12501..12614 + 114 Protein_14 IS6 family transposase -
HRS04_RS00080 (12752) 12752..12922 + 171 Protein_15 DsbA family protein -
HRS04_RS00085 (12912) 12912..13418 + 507 WP_000949452.1 protein disulfide oxidoreductase -
HRS04_RS00090 (13655) 13655..14416 + 762 WP_001225378.1 Na(+)-translocating NADH-quinone reductase subunit C -
HRS04_RS00095 (14763) 14763..16649 + 1887 WP_000118029.1 FTR1 family protein -
HRS04_RS00100 (16690) 16690..17217 + 528 WP_000178050.1 iron transporter -
HRS04_RS00105 (17321) 17321..18700 + 1380 WP_000119836.1 Fe-S-containing protein -
HRS04_RS00110 (18703) 18703..19986 + 1284 WP_000964653.1 ABC transporter permease -
HRS04_RS00115 (19976) 19976..21106 + 1131 WP_000729220.1 ABC transporter permease -
HRS04_RS00120 (21111) 21111..21806 + 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
HRS04_RS00125 (21793) 21793..22278 + 486 WP_001267177.1 TlpA disulfide reductase family protein -
HRS04_RS00130 (22303) 22303..22788 + 486 WP_000874189.1 hypothetical protein -
HRS04_RS00135 (22910) 22910..23440 + 531 Protein_26 histidine-type phosphatase -
HRS04_RS00140 (23498) 23498..24202 - 705 WP_001067834.1 IS6 family transposase IS26 Transposase
HRS04_RS00145 (24309) 24309..25169 + 861 WP_000557452.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
HRS04_RS00150 (25182) 25182..25724 + 543 WP_002063889.1 AAA family ATPase -
HRS04_RS00155 (25816) 25816..26864 + 1049 Protein_30 IS3 family transposase ISKpn11 Transposase
HRS04_RS00160 (26918) 26918..27622 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HRS04_RS00165 (27699) 27699..29918 - 2220 Protein_32 Tn3 family transposase TnpA_Tn3 Transposase
HRS04_RS00170 (29983) 29983..30276 + 294 WP_116961751.1 WbuC family cupin fold metalloprotein -
HRS04_RS00175 (30323) 30323..31198 - 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
HRS04_RS00180 (31454) 31454..31741 - 288 Protein_35 transposase -
HRS04_RS00185 (31807) 31807..32511 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HRS04_RS00190 (32565) 32565..33005 - 441 Protein_37 CatB-related O-acetyltransferase -
HRS04_RS00195 (33143) 33143..33973 - 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
HRS04_RS00200 (34104) 34104..34658 - 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
HRS04_RS00205 (34802) 34802..35506 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HRS04_RS00210 (35572) 35572..37086 + 1515 Protein_41 Tn3 family transposase TnpA_TnAs1 Transposase
HRS04_RS00215 (37128) 37128..37370 + 243 WP_032140899.1 hypothetical protein -
HRS04_RS00220 (37402) 37402..38052 - 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
HRS04_RS00225 (38146) 38146..39345 + 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
HRS04_RS00230 (39377) 39377..40261 - 885 WP_000058717.1 EamA family transporter -
HRS04_RS00235 (40399) 40399..40791 - 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
HRS04_RS00240 (40795) 40795..41544 + 750 Protein_47 Tn3 family transposase TnpA_TnAs1 Transposase
HRS04_RS00245 (41568) 41568..42173 - 606 WP_000509965.1 Tn3 family transposase TnpR_Tn5403 Transposase
HRS04_RS00250 (42268) 42268..45165 + 2898 WP_001553819.1 Tn3 family transposase TnpA_Tn5403 Transposase
HRS04_RS00255 (45302) 45302..45703 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
HRS04_RS00260 (45636) 45636..45893 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
HRS04_RS00265 (45986) 45986..46639 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
HRS04_RS00270 (47578) 47578..48435 - 858 WP_000130948.1 incFII family plasmid replication initiator RepA -
HRS04_RS00275 (48428) 48428..48502 - 75 WP_001365705.1 RepA leader peptide Tap -
HRS04_RS00280 (48738) 48738..48995 - 258 WP_000083821.1 replication regulatory protein RepA -
HRS04_RS00285 (49400) 49400..50422 + 1023 WP_000156883.1 IS110 family transposase ISSm1 Transposase
HRS04_RS00290 (50894) 50894..51247 + 354 WP_000005489.1 hypothetical protein -
HRS04_RS00295 (51660) 51660..52238 - 579 WP_032147503.1 DUF2726 domain-containing protein -
HRS04_RS00300 (52271) 52271..52964 + 694 Protein_59 IS1 family transposase IS1A Transposase
HRS04_RS00305 (53079) 53079..53435 + 357 WP_000229735.1 transposase -
HRS04_RS00310 (53432) 53432..53782 + 351 WP_000624725.1 IS66 family insertion sequence element accessory protein TnpB -
HRS04_RS00315 (53813) 53813..54034 + 222 WP_000080217.1 hypothetical protein -
HRS04_RS00320 (53986) 53986..54327 + 342 Protein_63 transposase -
HRS04_RS00325 (54391) 54391..54870 - 480 WP_001496175.1 ArgR family transcriptional regulator -
HRS04_RS00330 (54951) 54951..56354 - 1404 WP_000514417.1 YfcC family protein -
HRS04_RS00335 (56402) 56402..57406 - 1005 WP_000154544.1 Ornithine carbamoyltransferase VF
HRS04_RS00340 (57491) 57491..58402 - 912 WP_000440183.1 carbamate kinase -
HRS04_RS00345 (58413) 58413..59633 - 1221 WP_000410951.1 arginine deiminase -
HRS04_RS00350 (60367) 60367..60954 + 588 Protein_69 VENN motif pre-toxin domain-containing protein -
HRS04_RS00355 (60954) 60954..61400 - 447 Protein_70 plasmid replication initiator RepA -
HRS04_RS00360 (61393) 61393..61467 - 75 WP_001365705.1 RepA leader peptide Tap -
HRS04_RS00365 (61703) 61703..61960 - 258 WP_000083833.1 replication regulatory protein RepA -
HRS04_RS00370 (62244) 62244..62393 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (62437) 62437..62498 + 62 NuclAT_1 - Antitoxin Detail
- (62437) 62437..62498 + 62 NuclAT_1 - Antitoxin Detail
- (62437) 62437..62498 + 62 NuclAT_1 - Antitoxin Detail
- (62437) 62437..62498 + 62 NuclAT_1 - Antitoxin Detail
HRS04_RS00375 (62637) 62637..62819 - 183 WP_000968309.1 hypothetical protein -
HRS04_RS00380 (62920) 62920..63622 + 703 Protein_75 IS1 family transposase IS1S Transposase
HRS04_RS00385 (63923) 63923..64135 - 213 WP_005012601.1 hypothetical protein -
HRS04_RS00390 (64268) 64268..64828 - 561 WP_000139363.1 fertility inhibition protein FinO -
HRS04_RS00395 (64883) 64883..65629 - 747 WP_000205701.1 conjugal transfer pilus acetylase TraX -
HRS04_RS00400 (65649) 65649..70919 - 5271 WP_012372808.1 Multifunctional conjugation protein TraI Relaxase
HRS04_RS00405 (70919) 70919..73081 - 2163 WP_033549787.1 type IV conjugative transfer system coupling protein TraD -
HRS04_RS00410 (73333) 73333..74064 - 732 WP_001734698.1 conjugal transfer complement resistance protein TraT -
HRS04_RS00415 (74078) 74078..74587 - 510 WP_024168260.1 conjugal transfer entry exclusion protein TraS -
HRS04_RS00420 (74584) 74584..77409 - 2826 WP_029702178.1 conjugal transfer mating-pair stabilization protein TraG -
HRS04_RS00425 (77406) 77406..78779 - 1374 WP_001696604.1 conjugal transfer pilus assembly protein TraH -
HRS04_RS00430 (78766) 78766..79158 - 393 WP_001462107.1 F-type conjugal transfer protein TrbF -
HRS04_RS00435 (79139) 79139..79480 - 342 WP_071594226.1 P-type conjugative transfer protein TrbJ -
HRS04_RS00440 (79410) 79410..79955 - 546 WP_000059832.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
HRS04_RS00445 (79942) 79942..80226 - 285 WP_000623730.1 type-F conjugative transfer system pilin chaperone TraQ -
HRS04_RS00450 (80353) 80353..80691 - 339 WP_001287905.1 conjugal transfer protein TrbA -
HRS04_RS00455 (80707) 80707..81450 - 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
HRS04_RS00460 (81443) 81443..81700 - 258 WP_000864318.1 conjugal transfer protein TrbE -
HRS04_RS00465 (81727) 81727..83535 - 1809 WP_001553831.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
HRS04_RS00470 (83532) 83532..84170 - 639 WP_001553832.1 type-F conjugative transfer system pilin assembly protein TrbC -
HRS04_RS00475 (84179) 84179..85171 - 993 WP_001553833.1 conjugal transfer pilus assembly protein TraU -
HRS04_RS00480 (85168) 85168..85800 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
HRS04_RS00485 (85797) 85797..86183 - 387 WP_000099690.1 type-F conjugative transfer system protein TrbI -
HRS04_RS00490 (86180) 86180..88807 - 2628 WP_001064264.1 type IV secretion system protein TraC -
HRS04_RS00495 (88967) 88967..89188 - 222 WP_001278692.1 conjugal transfer protein TraR -
HRS04_RS00500 (89323) 89323..89838 - 516 WP_000809832.1 type IV conjugative transfer system lipoprotein TraV -
HRS04_RS00505 (89835) 89835..90086 - 252 WP_001038342.1 conjugal transfer protein TrbG -
HRS04_RS00510 (90079) 90079..90399 - 321 Protein_101 conjugal transfer protein TrbD -
HRS04_RS00515 (90386) 90386..90976 - 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
HRS04_RS00520 (90966) 90966..92393 - 1428 WP_001553836.1 F-type conjugal transfer pilus assembly protein TraB -
HRS04_RS00525 (92393) 92393..93121 - 729 WP_001230813.1 type-F conjugative transfer system secretin TraK -
HRS04_RS00530 (93108) 93108..93674 - 567 WP_000399790.1 type IV conjugative transfer system protein TraE -
HRS04_RS00535 (93696) 93696..94007 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
HRS04_RS00540 (94022) 94022..94387 - 366 WP_000340282.1 type IV conjugative transfer system pilin TraA -
HRS04_RS00545 (94430) 94430..94645 - 216 WP_001352842.1 conjugal transfer relaxosome protein TraY -
HRS04_RS00550 (94781) 94781..95428 - 648 WP_000332520.1 conjugal transfer transcriptional regulator TraJ -
HRS04_RS00555 (95619) 95619..96002 - 384 WP_001063020.1 conjugal transfer relaxosome DNA-binding protein TraM -
HRS04_RS00560 (96372) 96372..96944 + 573 WP_000949660.1 hypothetical protein VF
HRS04_RS00565 (97240) 97240..98061 - 822 WP_001234465.1 DUF932 domain-containing protein -
HRS04_RS00570 (98180) 98180..98467 - 288 WP_000107242.1 hypothetical protein -
HRS04_RS00575 (98492) 98492..98698 - 207 WP_000275854.1 hypothetical protein -
HRS04_RS00580 (98768) 98768..99065 + 298 Protein_115 hypothetical protein -
HRS04_RS00585 (99366) 99366..99491 - 126 WP_096937776.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
HRS04_RS00590 (99433) 99433..99582 - 150 Protein_117 DUF5431 family protein -
- (99589) 99589..99787 - 199 NuclAT_0 - Antitoxin Detail
- (99589) 99589..99787 - 199 NuclAT_0 - Antitoxin Detail
- (99589) 99589..99787 - 199 NuclAT_0 - Antitoxin Detail
- (99589) 99589..99787 - 199 NuclAT_0 - Antitoxin Detail
HRS04_RS00595 (99756) 99756..99861 - 106 Protein_118 plasmid SOS inhibition protein A -
HRS04_RS00600 (100016) 100016..100333 + 318 Protein_119 IS110 family transposase -
HRS04_RS00605 (100622) 100622..100873 - 252 Protein_120 iron-containing alcohol dehydrogenase -
HRS04_RS00610 (100958) 100958..101470 - 513 WP_223350513.1 potassium channel family protein -
HRS04_RS00615 (101597) 101597..102290 - 694 Protein_122 IS1 family transposase IS1A Transposase
HRS04_RS00620 (102347) 102347..102451 + 105 Protein_123 thiosulfate reductase cytochrome B subunit -
HRS04_RS00625 (102697) 102697..104091 - 1395 WP_001037799.1 carbohydrate porin -
HRS04_RS00630 (104286) 104286..105719 - 1434 WP_024170639.1 glycoside hydrolase family 32 protein -
HRS04_RS00635 (105716) 105716..106993 - 1278 WP_001083369.1 MFS transporter -
HRS04_RS00640 (107056) 107056..109182 - 2127 WP_000253905.1 alpha-galactosidase -
HRS04_RS00645 (109278) 109278..110288 - 1011 WP_000053332.1 substrate-binding domain-containing protein -
HRS04_RS00650 (110446) 110446..111204 - 759 Protein_129 site-specific integrase -
HRS04_RS00655 (111295) 111295..112523 + 1229 WP_152924612.1 IS3 family transposase IS2 Transposase
HRS04_RS00660 (112508) 112508..113077 + 570 WP_089634947.1 hypothetical protein -
HRS04_RS00665 (114008) 114008..114283 - 276 WP_071780182.1 hypothetical protein -
HRS04_RS00670 (114178) 114178..114408 - 231 WP_021526513.1 hypothetical protein -
HRS04_RS00675 (114434) 114434..114997 - 564 WP_001348621.1 class I SAM-dependent methyltransferase -
HRS04_RS00680 (115045) 115045..116406 - 1362 WP_000170714.1 DUF3560 domain-containing protein -
HRS04_RS00685 (116458) 116458..116688 - 231 WP_000218642.1 hypothetical protein -
HRS04_RS00690 (117723) 117723..117914 - 192 WP_001027516.1 hypothetical protein -
HRS04_RS00695 (117911) 117911..118333 - 423 WP_000271753.1 DUF1380 family protein -
HRS04_RS00700 (118380) 118380..118805 - 426 WP_001198928.1 antirestriction protein -
HRS04_RS00705 (119222) 119222..119998 - 777 WP_001753849.1 hypothetical protein -
HRS04_RS00710 (120049) 120049..120567 - 519 WP_123325260.1 DUF1380 family protein -
HRS04_RS00715 (120497) 120497..120718 - 222 WP_001104873.1 hypothetical protein -
HRS04_RS00720 (120719) 120719..121402 - 684 WP_000086185.1 DNA methylase -
HRS04_RS00725 (121479) 121479..121790 - 312 WP_011254640.1 hypothetical protein -
HRS04_RS00730 (121787) 121787..122689 - 903 WP_001348615.1 DUF1281 domain-containing protein -
HRS04_RS00735 (123556) 123556..124527 - 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
HRS04_RS00740 (124527) 124527..125693 - 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
HRS04_RS00745 (126281) 126281..127036 - 756 WP_000852146.1 replication initiation protein RepE -
HRS04_RS00750 (127810) 127810..128616 - 807 WP_000016982.1 site-specific integrase -
HRS04_RS00755 (128617) 128617..128922 - 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
HRS04_RS00760 (128924) 128924..129142 - 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
HRS04_RS00765 (129776) 129776..129973 + 198 WP_000215657.1 hypothetical protein -
HRS04_RS00770 (129970) 129970..130254 - 285 WP_000642771.1 hypothetical protein -
HRS04_RS00775 (130274) 130274..131407 - 1134 WP_000545983.1 DUF3800 domain-containing protein -
HRS04_RS00780 (131670) 131670..134789 - 3120 WP_001553851.1 hypothetical protein -
HRS04_RS00785 (135096) 135096..135326 + 231 WP_001261287.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
HRS04_RS00790 (135323) 135323..135739 + 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
HRS04_RS00795 (135901) 135901..138039 - 2139 WP_000350635.1 AAA family ATPase -
HRS04_RS00800 (138504) 138504..139499 + 996 WP_000246636.1 hypothetical protein -
HRS04_RS00805 (139542) 139542..140435 + 894 WP_001553853.1 S-4TM family putative pore-forming effector -
HRS04_RS00815 (141483) 141483..144599 - 3117 WP_001553854.1 HsdR family type I site-specific deoxyribonuclease -
HRS04_RS00820 (144721) 144721..146004 - 1284 WP_001553855.1 restriction endonuclease subunit S -
HRS04_RS00825 (146001) 146001..147557 - 1557 WP_001553856.1 type I restriction-modification system subunit M -
HRS04_RS00830 (147740) 147740..147961 + 222 WP_001190712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
HRS04_RS00835 (147961) 147961..148341 + 381 WP_001216034.1 type II toxin-antitoxin system death-on-curing family toxin Toxin Detail
HRS04_RS00840 (148346) 148346..148525 + 180 WP_001513661.1 hypothetical protein -
HRS04_RS00845 (148553) 148553..148831 + 279 Protein_168 pdcB -
HRS04_RS00850 (148836) 148836..149249 + 414 Protein_169 IS3 family transposase ISLad1 Transposase
HRS04_RS00855 (149199) 149199..149534 - 336 WP_169329198.1 type I deoxyribonuclease HsdR -
HRS04_RS00860 (149744) 149744..150724 - 981 WP_000019407.1 IS5 family transposase IS5D Transposase
HRS04_RS00865 (150968) 150968..152371 + 1404 WP_001373486.1 S-methylmethionine permease -
HRS04_RS00870 (152358) 152358..153290 + 933 WP_000081352.1 homocysteine S-methyltransferase -
HRS04_RS00875 (153399) 153399..153728 - 330 Protein_174 TOBE domain-containing protein -
HRS04_RS00885 (154718) 154718..155688 - 971 Protein_176 hypothetical protein -
HRS04_RS00890 (156444) 156444..157421 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
HRS04_RS00895 (157706) 157706..158446 - 741 WP_001066953.1 tyrosine-type recombinase/integrase -
HRS04_RS00900 (158567) 158567..158749 - 183 WP_042344623.1 hypothetical protein -
HRS04_RS00905 (158816) 158816..159105 - 290 Protein_180 type II toxin-antitoxin system RelE/ParE family toxin -
HRS04_RS00910 (159092) 159092..159360 - 269 Protein_181 type II toxin-antitoxin system ParD family antitoxin -
HRS04_RS00915 (159892) 159892..161061 + 1170 WP_001072355.1 hypothetical protein -
HRS04_RS00920 (161094) 161094..161222 + 129 Protein_183 IS481 family transposase -
HRS04_RS00925 (161347) 161347..161550 - 204 Protein_184 hypothetical protein -
HRS04_RS00930 (161656) 161656..161931 - 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin -
HRS04_RS00935 (161931) 161931..162215 - 285 WP_001387467.1 ribbon-helix-helix domain-containing protein -
HRS04_RS00940 (162820) 162820..163572 + 753 WP_000562172.1 IclR family transcriptional regulator -
HRS04_RS00945 (163618) 163618..164583 - 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
HRS04_RS00950 (164616) 164616..164996 - 381 WP_000710783.1 Rid family detoxifying hydrolase -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance