MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 99734 bp
Accession: NZ_CP053724 Location: 1..99734 Organism: Escherichia coli strain CP66-6_Sichuan Replicon: plasmid pCP66-6-IncFIC
Accession: NZ_CP053724 Location: 1..99734 Organism: Escherichia coli strain CP66-6_Sichuan Replicon: plasmid pCP66-6-IncFIC
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HP433_RS23085 () | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| HP433_RS23090 () | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| HP433_RS23095 () | 2124..2291 | - | 168 | WP_063078056.1 | hypothetical protein | - |
| HP433_RS23100 () | 2406..2816 | - | 411 | Protein_3 | IS3 family transposase ISEhe3 | Transposase |
| HP433_RS23105 () | 2879..3496 | + | 618 | WP_172615465.1 | IS6 family transposase IS15DI | Transposase |
| HP433_RS23110 () | 3634..4251 | + | 618 | WP_172615465.1 | IS6 family transposase IS15DI | Transposase |
| HP433_RS23115 () | 4389..5093 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HP433_RS23120 () | 5147..5614 | + | 468 | Protein_7 | conjugal transfer protein | - |
| HP433_RS23125 () | 5859..5975 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| HP433_RS23130 () | 5991..7910 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| HP433_RS23135 () | 8029..8196 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| HP433_RS23140 () | 8436..9071 | + | 636 | Protein_11 | IS256 family transposase IS406 | Transposase |
| HP433_RS23145 () | 9336..9668 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| HP433_RS23150 () | 9838..10629 | - | 792 | WP_001206316.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HP433_RS23155 () | 10722..11981 | - | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| HP433_RS23160 () | 12243..13034 | - | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HP433_RS23165 () | 13040..13330 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HP433_RS23170 () | 13442..13939 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| HP433_RS23175 () | 14084..15097 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HP433_RS23180 () | 15300..15650 | + | 351 | WP_071830595.1 | DUF3330 domain-containing protein | - |
| HP433_RS23185 () | 15776..16336 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HP433_RS23190 () | 16339..19290 | + | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| HP433_RS23195 () | 19299..19700 | + | 402 | WP_046788546.1 | hypothetical protein | - |
| HP433_RS23200 () | 19785..20489 | - | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| HP433_RS23205 () | 20553..21383 | + | 831 | Protein_24 | IS91 family transposase ISVsa3 | Transposase |
| HP433_RS23210 () | 21414..22298 | + | 885 | WP_012728215.1 | DUF3363 domain-containing protein | - |
| HP433_RS23215 () | 22515..23729 | + | 1215 | WP_058657119.1 | Bicyclomycin resistance protein | ARG |
| HP433_RS23220 () | 23757..24062 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| HP433_RS23225 () | 24174..25667 | + | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| HP433_RS23230 () | 25698..25949 | + | 252 | WP_001445143.1 | hypothetical protein | - |
| HP433_RS23235 () | 25843..26145 | - | 303 | WP_000251875.1 | phosphoglucosamine mutase | - |
| HP433_RS23240 () | 26232..27047 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| HP433_RS23245 () | 27137..27565 | + | 429 | Protein_32 | IS4 family transposase ISAba1 | Transposase |
| HP433_RS23250 () | 27579..28787 | - | 1209 | WP_172615445.1 | IS4 family transposase IS10R | Transposase |
| HP433_RS23255 () | 28892..29565 | + | 674 | Protein_34 | IS4 family transposase | - |
| HP433_RS23260 () | 29749..30108 | - | 360 | WP_170628443.1 | phenol hydroxylase | - |
| HP433_RS23265 () | 30284..30988 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HP433_RS23270 () | 31054..32568 | + | 1515 | Protein_37 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HP433_RS23275 () | 32626..32868 | + | 243 | WP_000844627.1 | transposase | - |
| HP433_RS23280 () | 32900..33550 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HP433_RS23285 () | 33656..34855 | + | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| HP433_RS23290 () | 34887..35771 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| HP433_RS23295 () | 35909..36316 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| HP433_RS23300 () | 36306..37967 | + | 1662 | Protein_43 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HP433_RS23305 () | 37985..38326 | + | 342 | WP_072796249.1 | Late promoter-activating protein | - |
| HP433_RS23310 () | 38435..39139 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HP433_RS23315 () | 39329..40144 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HP433_RS23320 () | 40295..40999 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HP433_RS23325 () | 41063..41302 | + | 240 | WP_011264039.1 | macrolide transporter | - |
| HP433_RS23330 () | 41448..42311 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| HP433_RS23335 () | 42349..42594 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| HP433_RS23340 () | 43063..43854 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| HP433_RS23345 () | 44112..44972 | - | 861 | WP_050190632.1 | Beta-lactamase TEM | ARG |
| HP433_RS23350 () | 45155..45712 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HP433_RS23355 () | 46004..46708 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HP433_RS23360 () | 46861..47682 | - | 822 | WP_000939727.1 | hypothetical protein | ARG |
| HP433_RS23365 () | 47814..48605 | - | 792 | WP_065800310.1 | Streptomycin 3''-adenylyltransferase | ARG |
| HP433_RS23370 () | 48754..49551 | + | 798 | Protein_57 | IS91 family transposase ISAzo26 | Transposase |
| HP433_RS23375 () | 49604..50308 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HP433_RS23380 () | 50845..51387 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| HP433_RS23385 () | 51400..52260 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| HP433_RS23390 () | 52403..53077 | + | 675 | Protein_61 | IS4 family transposase IS10R | Transposase |
| HP433_RS23395 () | 53130..53834 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HP433_RS23400 () | 53902..55200 | + | 1299 | Protein_63 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HP433_RS23405 () | 55234..55734 | + | 501 | Protein_64 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HP433_RS23410 () | 55768..55956 | + | 189 | Protein_65 | transposase | - |
| HP433_RS23415 () | 56031..56318 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| HP433_RS23420 () | 56315..56566 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| HP433_RS23425 () | 57532..58389 | - | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| HP433_RS23430 () | 58382..58456 | - | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| HP433_RS23435 () | 58688..58945 | - | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| HP433_RS23440 () | 59213..59419 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 59406..59467 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 59406..59467 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 59406..59467 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 59406..59467 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| HP433_RS23445 () | 59809..60021 | - | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| HP433_RS23450 () | 60156..60566 | - | 411 | Protein_73 | fertility inhibition protein FinO | - |
| HP433_RS23455 () | 60569..63454 | - | 2886 | Protein_74 | Multifunctional conjugation protein TraI | Relaxase |
| HP433_RS23460 () | 63454..64554 | - | 1101 | Protein_75 | conjugal transfer protein TraH | - |
| HP433_RS23465 () | 64663..66477 | - | 1815 | Protein_76 | type IV secretion system protein TraC | - |
| HP433_RS23470 () | 66637..66858 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| HP433_RS23475 () | 66993..67508 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HP433_RS23480 () | 67505..67873 | - | 369 | WP_077254276.1 | conjugal transfer protein TrbD | - |
| HP433_RS23485 () | 67812..68399 | - | 588 | WP_000002772.1 | conjugal transfer protein TraP | - |
| HP433_RS23490 () | 68389..68904 | - | 516 | Protein_81 | conjugal transfer protein TrbI | - |
| HP433_RS23495 () | 69122..69280 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 69324..69548 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69324..69548 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69324..69548 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 69324..69548 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| HP433_RS23500 () | 69360..69548 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| HP433_RS23505 () | 69560..70279 | - | 720 | WP_013362833.1 | plasmid SOS inhibition protein A | - |
| HP433_RS23510 () | 70276..70683 | - | 408 | WP_172615466.1 | conjugation system SOS inhibitor PsiB | - |
| HP433_RS23515 () | 70649..70915 | - | 267 | Protein_86 | class I SAM-dependent methyltransferase | - |
| HP433_RS23520 () | 70963..72324 | - | 1362 | WP_000170715.1 | DUF3560 domain-containing protein | - |
| HP433_RS23525 () | 72376..72606 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| HP433_RS23530 () | 73510..73887 | + | 378 | WP_000457136.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HP433_RS23535 () | 73887..75158 | + | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| HP433_RS23540 () | 75163..75555 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| HP433_RS23545 () | 75560..76531 | - | 972 | WP_001103690.1 | hypothetical protein | - |
| HP433_RS23550 () | 76753..77397 | + | 645 | WP_000633913.1 | AAA family ATPase | - |
| HP433_RS23555 () | 77391..77666 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| HP433_RS23560 () | 77818..78594 | - | 777 | Protein_95 | phage integrase family protein | - |
| HP433_RS23565 () | 78591..79022 | - | 432 | WP_001707302.1 | hypothetical protein | - |
| HP433_RS23570 () | 79088..79792 | + | 705 | WP_065304467.1 | IS6 family transposase IS26 | Transposase |
| HP433_RS23575 () | 79941..81266 | - | 1326 | WP_001046306.1 | pyridine nucleotide-disulfide oxidoreductase | - |
| HP433_RS23580 () | 81376..82073 | + | 698 | Protein_99 | IS1 family transposase IS1R | Transposase |
| HP433_RS23585 () | 82174..82455 | - | 282 | WP_000639434.1 | hypothetical protein | - |
| HP433_RS23590 () | 82557..83453 | - | 897 | Protein_101 | IS3 family transposase ISEhe3 | Transposase |
| HP433_RS23595 () | 83518..84336 | + | 819 | Protein_102 | IS30 family transposase IS30D | Transposase |
| HP433_RS23605 () | 85644..85820 | + | 177 | Protein_104 | IS30 family transposase | - |
| HP433_RS23610 () | 86245..86529 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| HP433_RS23615 () | 86549..87682 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| HP433_RS23620 () | 87945..91063 | - | 3119 | Protein_107 | hypothetical protein | - |
| HP433_RS23625 () | 91369..91599 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| HP433_RS23630 () | 91596..92012 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| HP433_RS23635 () | 92174..94312 | - | 2139 | WP_039002805.1 | AAA family ATPase | - |
| HP433_RS23640 () | 94777..95772 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| HP433_RS23645 () | 95776..96708 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| HP433_RS23650 () | 96845..97542 | - | 698 | Protein_113 | IS1 family transposase IS1R | Transposase |
| HP433_RS23655 () | 97600..97848 | + | 249 | Protein_114 | abortive infection family protein | - |
| HP433_RS23660 () | 98137..98949 | - | 813 | WP_032333019.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|