MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 113351 bp
Accession: NZ_CP051610 Location: 1..113351 Organism: Escherichia coli O25b:H4-ST131 strain 2019_APHA Replicon: plasmid pAPHA_2019
Accession: NZ_CP051610 Location: 1..113351 Organism: Escherichia coli O25b:H4-ST131 strain 2019_APHA Replicon: plasmid pAPHA_2019
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HHM37_RS24425 () | 1..858 | + | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| HHM37_RS24430 () | 1798..2451 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HHM37_RS24435 () | 2544..2801 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HHM37_RS24440 () | 2734..3135 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HHM37_RS24445 () | 3384..3799 | + | 416 | Protein_4 | IS1 family transposase | - |
| HHM37_RS24450 () | 3835..4380 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HHM37_RS24455 () | 4446..5150 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HHM37_RS24460 () | 5464..6339 | + | 876 | WP_032277257.1 | hypothetical protein | ARG |
| HHM37_RS24465 () | 6374..6736 | + | 363 | Protein_8 | IS5 family transposase IS903B | Transposase |
| HHM37_RS24470 () | 6796..7500 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HHM37_RS24475 () | 7553..7885 | + | 333 | Protein_10 | EamA family transporter | - |
| HHM37_RS24480 () | 7917..9116 | - | 1200 | WP_000804064.1 | Multidrug resistance protein MdtG | ARG |
| HHM37_RS24485 () | 9222..9848 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HHM37_RS24490 () | 9880..10116 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| HHM37_RS24495 () | 10170..11006 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| HHM37_RS24500 () | 11006..11809 | - | 804 | WP_001082319.1 | hypothetical protein | ARG |
| HHM37_RS24505 () | 11870..12685 | - | 816 | WP_001043260.1 | hypothetical protein | ARG |
| HHM37_RS24510 () | 12993..13169 | - | 177 | Protein_17 | replication protein C | - |
| HHM37_RS24515 () | 13230..13934 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HHM37_RS24520 () | 14056..14961 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| HHM37_RS24525 () | 14958..16196 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| HHM37_RS24530 () | 16196..16780 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| HHM37_RS24535 () | 17273..18037 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| HHM37_RS24540 () | 18155..18220 | - | 66 | Protein_23 | EAL domain-containing protein | - |
| HHM37_RS24545 () | 18264..18569 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| HHM37_RS24550 () | 18580..19785 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| HHM37_RS24555 () | 19941..20144 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| HHM37_RS24560 () | 20272..21111 | - | 840 | WP_000259031.1 | hypothetical protein | ARG |
| HHM37_RS24565 () | 21105..21452 | - | 348 | WP_000679427.1 | Spermidine export protein MdtJ | ARG |
| HHM37_RS24570 () | 21658..22446 | - | 789 | WP_000503573.1 | hypothetical protein | ARG |
| HHM37_RS24575 () | 22577..23050 | - | 474 | WP_001389366.1 | hypothetical protein | ARG |
| HHM37_RS24580 () | 23208..23936 | + | 729 | Protein_31 | IS91 family transposase ISAzo26 | Transposase |
| HHM37_RS24585 () | 24002..24706 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HHM37_RS24590 () | 24898..25461 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| HHM37_RS24595 () | 25509..26870 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| HHM37_RS24600 () | 26922..27152 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| HHM37_RS24605 () | 28187..28378 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| HHM37_RS24610 () | 28375..28797 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| HHM37_RS24615 () | 28844..29146 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| HHM37_RS24620 () | 29686..30462 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| HHM37_RS24625 () | 30513..30947 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| HHM37_RS24630 () | 30961..31182 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| HHM37_RS24635 () | 31183..31866 | - | 684 | WP_000086185.1 | DNA methylase | - |
| HHM37_RS24640 () | 31943..32247 | - | 305 | Protein_43 | hypothetical protein | - |
| HHM37_RS24645 () | 32251..33153 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| HHM37_RS24650 () | 34020..34991 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HHM37_RS24655 () | 34991..36157 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| HHM37_RS24660 () | 36745..37500 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| HHM37_RS24665 () | 38274..39080 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| HHM37_RS24670 () | 39081..39386 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| HHM37_RS24675 () | 39388..39606 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| HHM37_RS24680 () | 40314..41309 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| HHM37_RS24685 () | 41313..42245 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| HHM37_RS24690 () | 42382..43079 | - | 698 | Protein_53 | IS1 family transposase IS1R | Transposase |
| HHM37_RS24695 () | 43293..46409 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| HHM37_RS24700 () | 46531..47802 | - | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| HHM37_RS24705 () | 47799..49355 | - | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| HHM37_RS24710 () | 49538..49759 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| HHM37_RS24715 () | 49759..50139 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| HHM37_RS24720 () | 50144..50323 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| HHM37_RS24725 () | 50351..50710 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| HHM37_RS24730 () | 50634..51047 | + | 414 | Protein_61 | DDE-type integrase/transposase/recombinase | - |
| HHM37_RS24735 () | 50997..51314 | - | 318 | WP_001513659.1 | hypothetical protein | - |
| HHM37_RS24740 () | 51542..52558 | - | 1017 | WP_012372828.1 | IS5 family transposase IS5D | Transposase |
| HHM37_RS24745 () | 52766..54169 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| HHM37_RS24750 () | 54156..55088 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| HHM37_RS24755 () | 55197..55526 | - | 330 | Protein_66 | TOBE domain-containing protein | - |
| HHM37_RS24760 () | 55542..56239 | - | 698 | Protein_67 | IS1 family transposase IS1R | Transposase |
| HHM37_RS24765 () | 56295..56873 | + | 579 | Protein_68 | hypothetical protein | VF |
| HHM37_RS24770 () | 56880..57671 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| HHM37_RS24775 () | 57734..58342 | - | 609 | Protein_70 | IS66 family transposase ISEc22 | Transposase |
| HHM37_RS24780 () | 58410..59189 | - | 780 | WP_001323403.1 | IS21 family transposase IS100kyp | Transposase |
| HHM37_RS24785 () | 59189..60211 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| HHM37_RS24790 () | 60297..61232 | - | 936 | Protein_73 | IS66 family transposase ISEc22 | Transposase |
| HHM37_RS24795 () | 61281..61628 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| HHM37_RS24800 () | 61625..62029 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| HHM37_RS24805 () | 62058..62441 | - | 384 | Protein_76 | IS3 family transposase IS629 | Transposase |
| HHM37_RS24810 () | 62531..64039 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| HHM37_RS24815 () | 64712..65451 | - | 740 | Protein_78 | IS3 family transposase IS629 | Transposase |
| HHM37_RS24820 () | 65477..65782 | + | 306 | Protein_79 | IS91 family transposase ISSbo1 | Transposase |
| HHM37_RS24825 () | 66305..67480 | - | 1176 | WP_001020413.1 | hypothetical protein | VF |
| HHM37_RS24830 () | 67549..69810 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| HHM37_RS24835 () | 69979..70755 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| HHM37_RS24840 () | 70763..71638 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| HHM37_RS24845 () | 71970..72517 | - | 548 | Protein_84 | replication initiation protein | - |
| HHM37_RS24850 () | 74089..74424 | - | 336 | WP_001080732.1 | colicin transporter | - |
| HHM37_RS24855 () | 74553..74900 | + | 348 | WP_000142452.1 | hypothetical protein | - |
| HHM37_RS24860 () | 74920..75429 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| HHM37_RS24865 () | 75426..75686 | - | 261 | WP_000371882.1 | hypothetical protein | - |
| HHM37_RS24870 () | 75788..76527 | + | 740 | Protein_89 | IS3 family transposase IS629 | Transposase |
| HHM37_RS24875 () | 77200..77514 | + | 315 | Protein_90 | IS5 family transposase ISKpn26 | Transposase |
| HHM37_RS24880 () | 77515..77688 | + | 174 | Protein_91 | IS5 family transposase ISKpn26 | Transposase |
| HHM37_RS24885 () | 77838..78471 | - | 634 | Protein_92 | histidine-type phosphatase | - |
| HHM37_RS24890 () | 78593..79078 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| HHM37_RS24895 () | 79103..79588 | - | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| HHM37_RS24900 () | 79575..80270 | - | 696 | WP_000117262.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| HHM37_RS24905 () | 80275..81405 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| HHM37_RS24910 () | 81395..82678 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| HHM37_RS24915 () | 82681..84060 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| HHM37_RS24920 () | 84164..84691 | - | 528 | WP_000178050.1 | iron transporter | - |
| HHM37_RS24925 () | 84732..86618 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| HHM37_RS24930 () | 86965..87780 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| HHM37_RS24935 () | 87963..88469 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| HHM37_RS24940 () | 88459..88617 | - | 159 | WP_000449408.1 | DsbA family protein | - |
| HHM37_RS24945 () | 89080..89777 | + | 698 | Protein_104 | IS1 family transposase IS1X2 | Transposase |
| HHM37_RS24950 () | 89793..90035 | - | 243 | Protein_105 | hypothetical protein | - |
| HHM37_RS24955 () | 90238..90969 | - | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| HHM37_RS24960 () | 91001..91498 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| HHM37_RS24965 () | 91517..94336 | - | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| HHM37_RS24970 () | 94333..95706 | - | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| HHM37_RS24975 () | 95693..96118 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| HHM37_RS24980 () | 96066..96413 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| HHM37_RS24985 () | 96343..96888 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HHM37_RS24990 () | 96875..97159 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HHM37_RS24995 () | 97286..97606 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| HHM37_RS25000 () | 97654..98351 | - | 698 | Protein_115 | IS1 family transposase IS1G | Transposase |
| HHM37_RS25005 () | 98409..98951 | + | 543 | WP_089455070.1 | hypothetical protein | - |
| HHM37_RS25010 () | 98948..101182 | + | 2235 | WP_086908463.1 | type IV conjugative transfer system coupling protein TraD | - |
| HHM37_RS25015 () | 101182..106452 | + | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| HHM37_RS25020 () | 106472..107218 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| HHM37_RS25025 () | 107273..107833 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| HHM37_RS25030 () | 107964..108176 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| HHM37_RS25035 () | 108735..109127 | + | 393 | WP_185161629.1 | IS66 family transposase ISEc23 | Transposase |
| HHM37_RS25040 () | 109161..109858 | + | 698 | Protein_123 | IS1 family transposase | - |
| HHM37_RS25045 () | 109933..110283 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| HHM37_RS25050 () | 110314..111927 | + | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| HHM37_RS25055 () | 112005..112291 | + | 287 | Protein_126 | DUF2726 domain-containing protein | - |
| - () | 112258..112318 | - | 61 | NuclAT_0 | - | - |
| - () | 112258..112318 | - | 61 | NuclAT_0 | - | - |
| - () | 112258..112318 | - | 61 | NuclAT_0 | - | - |
| - () | 112258..112318 | - | 61 | NuclAT_0 | - | - |
| HHM37_RS25060 () | 112363..112497 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HHM37_RS25065 () | 112794..113048 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| HHM37_RS25070 () | 113285..113351 | + | 67 | WP_185161630.1 | RepA leader peptide Tap | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|