MGE detailed information
MGE type: Conjugative plasmid MGE length: 113995 bp
Accession: NZ_CP046417 Location: 1..113995 Organism: Escherichia coli strain LZYWN_4 Replicon: plasmid pS4-aph
Accession: NZ_CP046417 Location: 1..113995 Organism: Escherichia coli strain LZYWN_4 Replicon: plasmid pS4-aph
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GJV83_RS22895 () | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| GJV83_RS22900 () | 1263..2003 | - | 741 | WP_072652774.1 | IS91 family transposase ISMno23 | Transposase |
| GJV83_RS22905 () | 2124..2291 | - | 168 | WP_063078056.1 | hypothetical protein | - |
| GJV83_RS22910 () | 2406..3095 | - | 690 | Protein_3 | IS3 family transposase ISEhe3 | Transposase |
| GJV83_RS22915 () | 3130..3273 | - | 144 | Protein_4 | transposase domain-containing protein | - |
| GJV83_RS22920 () | 3338..4042 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GJV83_RS22925 () | 4096..4563 | + | 468 | Protein_6 | conjugal transfer protein | - |
| GJV83_RS22930 () | 4808..4924 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| GJV83_RS22935 () | 4940..6859 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| GJV83_RS22940 () | 6978..7145 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| GJV83_RS22945 () | 7385..8020 | + | 636 | Protein_10 | IS256 family transposase IS406 | Transposase |
| GJV83_RS22950 () | 8165..8869 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| GJV83_RS22955 () | 8923..9123 | + | 201 | Protein_12 | IS6 family transposase IS26 | Transposase |
| GJV83_RS22960 () | 9196..9435 | + | 240 | WP_011264039.1 | macrolide transporter | - |
| GJV83_RS22965 () | 9581..10444 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| GJV83_RS22970 () | 10482..10727 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| GJV83_RS22975 () | 11196..11987 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| GJV83_RS22980 () | 11990..12265 | - | 276 | WP_109023896.1 | hypothetical protein | - |
| GJV83_RS22985 () | 12267..12902 | + | 636 | Protein_18 | IS256 family transposase IS406 | Transposase |
| GJV83_RS22990 () | 13323..14294 | + | 972 | WP_032482493.1 | IS91 family transposase ISAzo26 | Transposase |
| GJV83_RS22995 () | 14591..15571 | + | 981 | Protein_20 | IS5 family transposase ISKpn26 | Transposase |
| GJV83_RS23000 () | 15696..15905 | - | 210 | Protein_21 | hypothetical protein | - |
| GJV83_RS23005 () | 16340..16555 | + | 216 | WP_034167711.1 | hypothetical protein | - |
| GJV83_RS23010 () | 16754..16951 | - | 198 | WP_032482496.1 | DUF2384 domain-containing protein | - |
| GJV83_RS23015 () | 17013..17420 | + | 408 | WP_034167712.1 | hypothetical protein | - |
| GJV83_RS23020 () | 17653..20619 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| GJV83_RS23025 () | 20623..21183 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| GJV83_RS23030 () | 21294..21998 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| GJV83_RS23035 () | 22071..22295 | + | 225 | WP_000743213.1 | hypothetical protein | - |
| GJV83_RS23040 () | 22506..23939 | + | 1434 | WP_206970424.1 | IS91 family transposase ISVsa3 | Transposase |
| GJV83_RS23045 () | 23936..25435 | - | 1500 | Protein_30 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| GJV83_RS23050 () | 25521..26273 | + | 753 | WP_000602738.1 | IS6 family transposase | - |
| GJV83_RS23055 () | 26324..26689 | - | 366 | Protein_32 | AAC(3) family N-acetyltransferase | - |
| GJV83_RS23060 () | 26695..27720 | - | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| GJV83_RS23065 () | 27949..28725 | - | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| GJV83_RS23070 () | 28839..29543 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| GJV83_RS23075 () | 29786..30646 | + | 861 | WP_206970426.1 | Beta-lactamase TEM | ARG |
| GJV83_RS23080 () | 30823..31296 | + | 474 | WP_058100828.1 | hypothetical protein | - |
| GJV83_RS23085 () | 31602..32063 | - | 462 | WP_024172415.1 | hypothetical protein | - |
| GJV83_RS23090 () | 32067..32774 | - | 708 | WP_058100829.1 | hypothetical protein | - |
| GJV83_RS23095 () | 32776..33033 | - | 258 | WP_001685860.1 | hypothetical protein | - |
| GJV83_RS23100 () | 33129..33406 | - | 278 | Protein_41 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| GJV83_RS23105 () | 33406..33690 | - | 285 | WP_001407321.1 | ribbon-helix-helix domain-containing protein | - |
| GJV83_RS23110 () | 33779..33841 | - | 63 | Protein_43 | 3'-5' exonuclease | - |
| GJV83_RS23115 () | 33876..34083 | - | 208 | Protein_44 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| GJV83_RS23120 () | 34080..34349 | - | 270 | WP_021559054.1 | hypothetical protein | - |
| GJV83_RS23125 () | 34404..34562 | - | 159 | WP_072649723.1 | hypothetical protein | - |
| GJV83_RS23130 () | 35261..36118 | - | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| GJV83_RS23135 () | 36111..36185 | - | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| GJV83_RS23140 () | 36417..36674 | - | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| GJV83_RS23145 () | 36942..37148 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 37135..37196 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 37135..37196 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 37135..37196 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 37135..37196 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| GJV83_RS23150 () | 37538..37750 | - | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| GJV83_RS23155 () | 37885..38445 | - | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| GJV83_RS23160 () | 38500..39243 | - | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| GJV83_RS23165 () | 39263..44533 | - | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| GJV83_RS23170 () | 44533..46695 | - | 2163 | WP_065304458.1 | type IV conjugative transfer system coupling protein TraD | - |
| GJV83_RS23175 () | 46948..47679 | - | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| GJV83_RS23180 () | 47711..48214 | - | 504 | WP_201273844.1 | surface exclusion protein | - |
| GJV83_RS23185 () | 48229..51051 | - | 2823 | WP_001007048.1 | conjugal transfer mating pair stabilization protein TraG | - |
| GJV83_RS23190 () | 51048..52421 | - | 1374 | WP_170926237.1 | conjugal transfer protein TraH | - |
| GJV83_RS23195 () | 52421..52783 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| GJV83_RS23200 () | 52713..53258 | - | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| GJV83_RS23205 () | 53245..53526 | - | 282 | WP_039002206.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| GJV83_RS23210 () | 53642..54385 | - | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| GJV83_RS23215 () | 54378..54638 | - | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| GJV83_RS23220 () | 54665..56473 | - | 1809 | WP_115739629.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| GJV83_RS23225 () | 56470..57108 | - | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| GJV83_RS23230 () | 57117..58109 | - | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| GJV83_RS23235 () | 58106..58738 | - | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| GJV83_RS23240 () | 58735..59121 | - | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| GJV83_RS23245 () | 59118..61745 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| GJV83_RS23250 () | 61905..62126 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| GJV83_RS23255 () | 62261..62776 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| GJV83_RS23260 () | 62773..63141 | - | 369 | WP_071787938.1 | conjugal transfer protein TrbD | - |
| GJV83_RS23265 () | 63080..63667 | - | 588 | WP_000002772.1 | conjugal transfer protein TraP | - |
| GJV83_RS23270 () | 63657..65084 | - | 1428 | WP_000146690.1 | conjugal transfer protein TraB | - |
| GJV83_RS23275 () | 65084..65788 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| GJV83_RS23280 () | 65799..66365 | - | 567 | WP_044720357.1 | type IV conjugative transfer system protein TraE | - |
| GJV83_RS23285 () | 66387..66698 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| GJV83_RS23290 () | 66703..67065 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| GJV83_RS23295 () | 67098..67493 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| GJV83_RS23300 () | 67592..68281 | - | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| GJV83_RS23305 () | 68468..68851 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| GJV83_RS23310 () | 69172..69774 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| GJV83_RS23315 () | 70071..70892 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| GJV83_RS23320 () | 71015..71302 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| GJV83_RS23325 () | 72224..72382 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 72426..72650 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 72426..72650 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 72426..72650 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 72426..72650 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| GJV83_RS23330 () | 72462..72650 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| GJV83_RS23335 () | 72662..73381 | - | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| GJV83_RS23340 () | 73378..73812 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| GJV83_RS23345 () | 73867..75825 | - | 1959 | WP_039000998.1 | ParB/RepB/Spo0J family partition protein | - |
| GJV83_RS23350 () | 75890..76123 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| GJV83_RS23355 () | 76180..76719 | - | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| GJV83_RS23360 () | 76745..76951 | - | 207 | WP_000275853.1 | hypothetical protein | - |
| GJV83_RS23365 () | 77571..78134 | - | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| GJV83_RS23370 () | 78182..79543 | - | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| GJV83_RS23375 () | 79595..79825 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| GJV83_RS23380 () | 80860..81051 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| GJV83_RS23385 () | 81048..81470 | - | 423 | WP_062877221.1 | DUF1380 family protein | - |
| GJV83_RS23390 () | 81517..81819 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| GJV83_RS23395 () | 82359..83135 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| GJV83_RS23400 () | 83186..83620 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| GJV83_RS23405 () | 83634..83855 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| GJV83_RS23410 () | 83856..84539 | - | 684 | WP_000086185.1 | DNA methylase | - |
| GJV83_RS23415 () | 84616..84920 | - | 305 | Protein_104 | hypothetical protein | - |
| GJV83_RS23420 () | 84924..85826 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| GJV83_RS23425 () | 86244..86492 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| GJV83_RS23430 () | 86489..86926 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| GJV83_RS23435 () | 86926..88197 | + | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| GJV83_RS23440 () | 88202..88594 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| GJV83_RS23445 () | 88599..89570 | - | 972 | WP_001103690.1 | hypothetical protein | - |
| GJV83_RS23450 () | 89792..90436 | + | 645 | WP_000633913.1 | AAA family ATPase | - |
| GJV83_RS23455 () | 90430..90705 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| GJV83_RS23460 () | 90857..91633 | - | 777 | Protein_113 | phage integrase family protein | - |
| GJV83_RS23465 () | 91630..92061 | - | 432 | WP_001707302.1 | hypothetical protein | - |
| GJV83_RS23470 () | 92127..92831 | + | 705 | WP_065304467.1 | IS6 family transposase IS26 | Transposase |
| GJV83_RS23475 () | 92980..94305 | - | 1326 | WP_021512928.1 | pyridine nucleotide-disulfide oxidoreductase | - |
| GJV83_RS23480 () | 94415..95112 | + | 698 | Protein_117 | IS1 family transposase IS1R | Transposase |
| GJV83_RS23485 () | 95213..95494 | - | 282 | WP_000639434.1 | hypothetical protein | - |
| GJV83_RS23490 () | 95596..96492 | - | 897 | Protein_119 | IS3 family transposase ISEhe3 | Transposase |
| GJV83_RS23495 () | 96557..97375 | + | 819 | Protein_120 | IS30 family transposase IS30D | Transposase |
| GJV83_RS23505 () | 98683..98859 | + | 177 | Protein_122 | IS30 family transposase | - |
| GJV83_RS23510 () | 99284..99568 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| GJV83_RS23515 () | 99588..100721 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| GJV83_RS23520 () | 100984..104102 | - | 3119 | Protein_125 | hypothetical protein | - |
| GJV83_RS23525 () | 104408..104638 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| GJV83_RS23530 () | 104635..105051 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| GJV83_RS23535 () | 105213..107351 | - | 2139 | WP_039002805.1 | AAA family ATPase | - |
| GJV83_RS23540 () | 107816..108811 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| GJV83_RS23545 () | 108815..109747 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| GJV83_RS23550 () | 109884..110581 | - | 698 | Protein_131 | IS1 family transposase IS1D | Transposase |
| GJV83_RS23555 () | 110761..111090 | - | 330 | Protein_132 | TOBE domain-containing protein | - |
| GJV83_RS23560 () | 111106..111803 | - | 698 | Protein_133 | IS1 family transposase IS1R | Transposase |
| GJV83_RS23565 () | 111861..112109 | + | 249 | Protein_134 | abortive infection family protein | - |
| GJV83_RS23570 () | 112398..113210 | - | 813 | WP_032333019.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|