MGE detailed information
MGE type: Conjugative plasmid MGE length: 130329 bp
Accession: NZ_CP045691 Location: 1..130329 Organism: Klebsiella pneumoniae strain TK421 Replicon: plasmid pTK421_1
Accession: NZ_CP045691 Location: 1..130329 Organism: Klebsiella pneumoniae strain TK421 Replicon: plasmid pTK421_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GHA50_RS00010 () | 1..858 | + | 858 | WP_004152386.1 | incFII family plasmid replication initiator RepA | - |
| GHA50_RS00015 () | 2070..3107 | + | 1038 | WP_060655699.1 | beta-mannosidase | - |
| GHA50_RS00020 () | 3148..3501 | + | 354 | WP_060655700.1 | phage holin, lambda family | - |
| GHA50_RS00025 () | 3504..3920 | + | 417 | WP_060655701.1 | structural protein | - |
| GHA50_RS00030 () | 3941..4399 | + | 459 | WP_060655705.1 | lysis protein | - |
| GHA50_RS00035 () | 4570..5781 | + | 1212 | Protein_6 | cloacin | - |
| GHA50_RS00040 () | 5930..7144 | - | 1215 | WP_153459001.1 | IS91 family transposase ISVa3 | Transposase |
| GHA50_RS00045 () | 7506..8054 | + | 549 | WP_072124330.1 | thioredoxin fold domain-containing protein | - |
| GHA50_RS00050 () | 8263..8667 | + | 405 | WP_100781753.1 | Exc2 family lipoprotein | - |
| GHA50_RS00055 () | 8730..9425 | + | 696 | WP_153459002.1 | IS6 family transposase ISEas1 | Transposase |
| GHA50_RS00060 () | 9479..10387 | + | 909 | Protein_11 | Toxin RTX-I translocation ATP-binding protein | VF |
| GHA50_RS00065 () | 10664..11670 | - | 1007 | Protein_12 | tyrosine-type recombinase/integrase | - |
| GHA50_RS00070 () | 11875..12057 | + | 183 | WP_153459003.1 | hypothetical protein | - |
| GHA50_RS00075 () | 12054..12497 | + | 444 | WP_153459004.1 | NACHT domain-containing protein | - |
| GHA50_RS00080 () | 13014..13766 | + | 753 | WP_153459005.1 | hypothetical protein | - |
| GHA50_RS00085 () | 14084..14809 | - | 726 | WP_153459057.1 | hypothetical protein | - |
| GHA50_RS00090 () | 15133..15363 | - | 231 | WP_153459006.1 | hypothetical protein | - |
| GHA50_RS00095 () | 15377..15580 | - | 204 | WP_004213596.1 | hemolysin expression modulator Hha | - |
| GHA50_RS00100 () | 15641..16135 | - | 495 | WP_114499705.1 | DNA-binding protein | - |
| GHA50_RS00105 () | 16165..16737 | - | 573 | WP_064871561.1 | hypothetical protein | - |
| GHA50_RS00110 () | 16734..16982 | - | 249 | WP_004200907.1 | hypothetical protein | - |
| GHA50_RS00115 () | 17261..18280 | - | 1020 | WP_153459007.1 | IS110 family transposase ISEc11 | Transposase |
| GHA50_RS00120 () | 18924..19538 | + | 615 | Protein_23 | IS1 family transposase | - |
| GHA50_RS00125 () | 19916..20503 | - | 588 | Protein_24 | hypothetical protein | - |
| GHA50_RS00130 () | 20500..20800 | - | 301 | Protein_25 | hypothetical protein | - |
| GHA50_RS00135 () | 20772..21026 | - | 255 | WP_153459008.1 | autotransporter outer membrane beta-barrel domain-containing protein | - |
| GHA50_RS00140 () | 21011..21258 | + | 248 | Protein_27 | TSUP family transporter | - |
| GHA50_RS00145 () | 21354..21533 | - | 180 | WP_153459009.1 | hypothetical protein | - |
| GHA50_RS00150 () | 21716..22978 | + | 1263 | WP_153459010.1 | DUF1479 domain-containing protein | - |
| GHA50_RS00155 () | 23039..24004 | - | 966 | WP_153459011.1 | glucokinase | - |
| GHA50_RS00160 () | 24048..25307 | - | 1260 | WP_153459012.1 | L-fucose-proton symporter | VF |
| GHA50_RS00170 () | 27225..28100 | - | 876 | WP_153459014.1 | MBL fold metallo-hydrolase | - |
| GHA50_RS00175 () | 28477..29403 | - | 927 | WP_153459015.1 | MBL fold metallo-hydrolase | - |
| GHA50_RS00180 () | 29735..30643 | + | 909 | WP_153459016.1 | HTH-type transcriptional regulator PgrR | VF |
| GHA50_RS00185 () | 31153..32085 | + | 933 | WP_153459017.1 | nucleoside recognition family protein | - |
| GHA50_RS00190 () | 32201..33343 | + | 1143 | WP_194285403.1 | NADH-dependent flavin oxidoreductase | - |
| GHA50_RS00195 () | 33428..34300 | + | 873 | WP_153459019.1 | alpha/beta fold hydrolase | - |
| GHA50_RS00200 () | 34305..34673 | + | 369 | WP_153459020.1 | hypothetical protein | - |
| GHA50_RS00205 () | 34670..35542 | + | 873 | WP_153459021.1 | DsbA family protein | - |
| GHA50_RS00210 () | 35746..36726 | + | 981 | WP_153459022.1 | nitronate monooxygenase | - |
| GHA50_RS00215 () | 36956..37609 | - | 654 | WP_032733156.1 | LysE family translocator | - |
| GHA50_RS00220 () | 37738..38154 | - | 417 | WP_153459023.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| GHA50_RS00225 () | 38151..38381 | - | 231 | WP_153459024.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| GHA50_RS00230 () | 38827..39207 | + | 381 | WP_015874975.1 | YrzE family protein | - |
| GHA50_RS00235 () | 39364..40104 | - | 741 | WP_009653143.1 | abortive infection family protein | - |
| GHA50_RS00240 () | 40140..40928 | - | 789 | WP_117054846.1 | DUF2971 domain-containing protein | - |
| GHA50_RS00245 () | 40925..41545 | - | 621 | WP_117054845.1 | hypothetical protein | - |
| GHA50_RS00250 () | 41542..42237 | - | 696 | WP_153459025.1 | DNA-binding protein | - |
| GHA50_RS00255 () | 42423..42713 | + | 291 | WP_153459026.1 | hypothetical protein | - |
| GHA50_RS00260 () | 42703..43602 | + | 900 | WP_032650492.1 | nucleotide-binding protein | - |
| GHA50_RS00265 () | 43652..45877 | - | 2226 | WP_032650494.1 | exclusion suppressor FxsA | - |
| GHA50_RS00270 () | 45879..46967 | - | 1089 | WP_114268690.1 | transcriptional repressor PifC | - |
| GHA50_RS00275 () | 47222..47965 | - | 744 | WP_153459027.1 | hypothetical protein | - |
| GHA50_RS00280 () | 47997..48413 | - | 417 | WP_153459028.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| GHA50_RS00285 () | 48410..48640 | - | 231 | WP_153459029.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| GHA50_RS00290 () | 48950..49399 | + | 450 | WP_153459030.1 | hypothetical protein | - |
| GHA50_RS00295 () | 49472..50464 | - | 993 | WP_153459031.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| GHA50_RS26725 () | 50608..50808 | + | 201 | Protein_59 | hypothetical protein | - |
| GHA50_RS00300 () | 51023..51241 | + | 219 | WP_063445614.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| GHA50_RS00305 () | 51243..51548 | + | 306 | WP_006788214.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| GHA50_RS00310 () | 51740..52756 | + | 1017 | WP_065900162.1 | hypothetical protein | - |
| GHA50_RS00315 () | 52954..53739 | + | 786 | WP_063445612.1 | IS91 family transposase ISShvi3 | Transposase |
| GHA50_RS00320 () | 54606..55361 | + | 756 | WP_063445611.1 | replication initiation protein RepE | - |
| GHA50_RS00330 () | 56065..57270 | + | 1206 | WP_000368714.1 | AAA family ATPase | - |
| GHA50_RS00335 () | 57270..58244 | + | 975 | WP_001568034.1 | ParB/RepB/Spo0J family partition protein | - |
| GHA50_RS00340 () | 58326..59597 | - | 1272 | WP_153459033.1 | Y-family DNA polymerase | - |
| GHA50_RS00345 () | 59597..60028 | - | 432 | WP_114446785.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| GHA50_RS00350 () | 60261..61232 | + | 972 | WP_077255919.1 | StbA family protein | - |
| GHA50_RS00355 () | 61235..61906 | + | 672 | WP_042938938.1 | plasmid partitioning/stability family protein | - |
| GHA50_RS00360 () | 61970..62200 | + | 231 | WP_023329036.1 | hypothetical protein | - |
| GHA50_RS00365 () | 62637..63338 | + | 702 | WP_042938937.1 | DNA methylase | - |
| GHA50_RS00370 () | 63338..63559 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| GHA50_RS00375 () | 63569..63988 | + | 420 | WP_042938936.1 | DUF1380 domain-containing protein | - |
| GHA50_RS00380 () | 64042..64809 | + | 768 | WP_153459034.1 | hypothetical protein | - |
| GHA50_RS00385 () | 65314..65742 | + | 429 | WP_135778113.1 | antirestriction protein | - |
| GHA50_RS00390 () | 65785..66291 | + | 507 | WP_153459035.1 | antirestriction protein ArdA | - |
| GHA50_RS00395 () | 66575..66829 | + | 255 | WP_074442020.1 | DNA polymerase III subunit theta | - |
| GHA50_RS00400 () | 66864..67184 | + | 321 | WP_071080835.1 | hypothetical protein | - |
| GHA50_RS00405 () | 67879..68421 | + | 543 | WP_153459036.1 | single-stranded DNA-binding protein | - |
| GHA50_RS00410 () | 68470..68718 | + | 249 | WP_040107914.1 | DUF905 domain-containing protein | - |
| GHA50_RS00415 () | 68787..70787 | + | 2001 | WP_114261272.1 | ParB/RepB/Spo0J family partition protein | - |
| GHA50_RS00420 () | 70832..71263 | + | 432 | WP_038992715.1 | conjugation system SOS inhibitor PsiB | - |
| GHA50_RS00425 () | 71260..71988 | + | 729 | WP_114261271.1 | plasmid SOS inhibition protein A | - |
| GHA50_RS00430 () | 71985..72311 | + | 327 | WP_004152639.1 | hypothetical protein | - |
| GHA50_RS00435 () | 72367..72741 | + | 375 | WP_114261270.1 | hypothetical protein | - |
| GHA50_RS00440 () | 72969..73130 | + | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| GHA50_RS00445 () | 73508..73780 | + | 273 | WP_023292062.1 | hypothetical protein | - |
| GHA50_RS00450 () | 73777..74127 | + | 351 | WP_023340954.1 | hypothetical protein | - |
| GHA50_RS00455 () | 74143..74460 | + | 318 | WP_080895857.1 | hypothetical protein | - |
| GHA50_RS00460 () | 75296..75853 | + | 558 | WP_153459037.1 | single-stranded DNA-binding protein | - |
| GHA50_RS00465 () | 75902..76150 | + | 249 | WP_020804458.1 | DUF905 domain-containing protein | - |
| GHA50_RS00470 () | 76219..78218 | + | 2000 | Protein_93 | ParB/RepB/Spo0J family partition protein | - |
| GHA50_RS00475 () | 78259..78693 | + | 435 | WP_110244254.1 | conjugation system SOS inhibitor PsiB | - |
| GHA50_RS00480 () | 78690..79418 | + | 729 | WP_080895863.1 | plasmid SOS inhibition protein A | - |
| GHA50_RS26730 () | 79415..79724 | + | 310 | Protein_96 | theronine dehydrogenase | - |
| GHA50_RS00485 () | 79903..80596 | - | 694 | Protein_97 | IS6 family transposase | - |
| GHA50_RS00490 () | 80665..81102 | - | 438 | WP_049156567.1 | hypothetical protein | - |
| GHA50_RS00495 () | 81118..82326 | - | 1209 | WP_162536020.1 | MFS transporter | - |
| GHA50_RS00500 () | 82341..84764 | - | 2424 | WP_080895865.1 | TonB-dependent siderophore receptor | - |
| GHA50_RS00505 () | 84923..85903 | - | 981 | WP_110204407.1 | FecR family protein | - |
| GHA50_RS00510 () | 85893..86408 | - | 516 | WP_049156577.1 | putative RNA polymerase sigma factor FecI | VF |
| GHA50_RS00515 () | 86619..87152 | + | 534 | Protein_103 | IS110 family transposase ISAs16 | Transposase |
| GHA50_RS00520 () | 87918..88298 | + | 381 | WP_049155508.1 | hypothetical protein | - |
| GHA50_RS00525 () | 88365..88712 | + | 348 | WP_114261269.1 | hypothetical protein | - |
| GHA50_RS00530 () | 88801..89031 | + | 231 | WP_065905248.1 | hypothetical protein | - |
| GHA50_RS00535 () | 89078..89911 | + | 834 | WP_114261268.1 | N-6 DNA methylase | - |
| GHA50_RS00540 () | 90536..91066 | + | 531 | WP_023292160.1 | antirestriction protein | - |
| GHA50_RS00545 () | 91104..91583 | - | 480 | WP_110244260.1 | hypothetical protein | VF |
| GHA50_RS00550 () | 92015..92407 | + | 393 | WP_153459038.1 | relaxosome protein TraM | - |
| GHA50_RS00555 () | 93053..93346 | + | 294 | WP_153459058.1 | hypothetical protein | - |
| GHA50_RS00560 () | 93432..93632 | + | 201 | WP_048289787.1 | TraY domain-containing protein | - |
| GHA50_RS00565 () | 93701..94069 | + | 369 | WP_020316649.1 | type IV conjugative transfer system pilin TraA | - |
| GHA50_RS00570 () | 94083..94388 | + | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| GHA50_RS00575 () | 94408..94974 | + | 567 | WP_020316627.1 | type IV conjugative transfer system protein TraE | - |
| GHA50_RS00580 () | 94961..95701 | + | 741 | WP_013214019.1 | type-F conjugative transfer system secretin TraK | - |
| GHA50_RS00585 () | 95701..97125 | + | 1425 | WP_117244571.1 | conjugal transfer protein TraB | - |
| GHA50_RS00590 () | 97118..97543 | + | 426 | WP_153459039.1 | conjugal transfer protein TraP | - |
| GHA50_RS26735 () | 97570..97725 | + | 156 | WP_159215442.1 | hypothetical protein | - |
| GHA50_RS00595 () | 97745..98314 | + | 570 | WP_153459059.1 | type IV conjugative transfer system lipoprotein TraV | - |
| GHA50_RS00600 () | 98689..98868 | + | 180 | WP_071885113.1 | hypothetical protein | - |
| GHA50_RS00605 () | 98897..99187 | + | 291 | WP_032426790.1 | hypothetical protein | - |
| GHA50_RS00610 () | 99211..99429 | + | 219 | WP_004171484.1 | hypothetical protein | - |
| GHA50_RS00615 () | 99430..99747 | + | 318 | WP_153459040.1 | hypothetical protein | - |
| GHA50_RS00620 () | 99814..100218 | + | 405 | WP_153459041.1 | hypothetical protein | - |
| GHA50_RS00625 () | 100514..100912 | + | 399 | WP_194285401.1 | hypothetical protein | - |
| GHA50_RS00630 () | 100984..103623 | + | 2640 | WP_049155532.1 | type IV secretion system protein TraC | - |
| GHA50_RS00635 () | 103623..104012 | + | 390 | WP_109233425.1 | type-F conjugative transfer system protein TrbI | - |
| GHA50_RS00640 () | 104012..104638 | + | 627 | WP_153459043.1 | type-F conjugative transfer system protein TraW | - |
| GHA50_RS00645 () | 104680..105069 | + | 390 | WP_153459044.1 | hypothetical protein | - |
| GHA50_RS00650 () | 105066..106055 | + | 990 | WP_040107936.1 | conjugal transfer pilus assembly protein TraU | - |
| GHA50_RS00655 () | 106068..106706 | + | 639 | WP_109233427.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| GHA50_RS00660 () | 106765..108720 | + | 1956 | WP_153459045.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| GHA50_RS00665 () | 108752..108979 | + | 228 | WP_126065533.1 | conjugal transfer protein TrbE | - |
| GHA50_RS00670 () | 108990..109316 | + | 327 | WP_153459046.1 | hypothetical protein | - |
| GHA50_RS00675 () | 109337..110089 | + | 753 | WP_153459047.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| GHA50_RS00680 () | 110100..110339 | + | 240 | WP_023340931.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| GHA50_RS00685 () | 110311..110868 | + | 558 | WP_153459048.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| GHA50_RS00690 () | 110914..111357 | + | 444 | WP_153459049.1 | F-type conjugal transfer protein TrbF | - |
| GHA50_RS00695 () | 111335..112714 | + | 1380 | WP_023158000.1 | conjugal transfer protein TraH | - |
| GHA50_RS00700 () | 112714..115563 | + | 2850 | WP_153459050.1 | conjugal transfer mating pair stabilization protein TraG | - |
| GHA50_RS00705 () | 115566..116096 | + | 531 | WP_153459060.1 | conjugal transfer protein TraS | - |
| GHA50_RS00710 () | 116286..117017 | + | 732 | WP_004152629.1 | complement resistance protein TraT | - |
| GHA50_RS00715 () | 117379..119688 | + | 2310 | Protein_144 | type IV conjugative transfer system coupling protein TraD | - |
| GHA50_RS00720 () | 119688..124946 | + | 5259 | WP_153459052.1 | Multifunctional conjugation protein TraI | Relaxase |
| GHA50_RS00725 () | 125026..125751 | + | 726 | WP_153459053.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| GHA50_RS00730 () | 125908..126504 | + | 597 | WP_153459054.1 | fertility inhibition protein FinO | - |
| GHA50_RS26740 () | 126524..126870 | + | 347 | Protein_148 | hypothetical protein | - |
| GHA50_RS00745 () | 127338..127982 | + | 645 | WP_153459056.1 | hypothetical protein | - |
| GHA50_RS00750 () | 128038..128688 | + | 651 | WP_128206231.1 | DUF2726 domain-containing protein | - |
| GHA50_RS00755 () | 128685..128993 | + | 309 | WP_012539984.1 | hypothetical protein | - |
| GHA50_RS00760 () | 129170..129649 | + | 480 | WP_012539991.1 | Phospholipase D | VF |
| GHA50_RS00765 () | 129768..130037 | + | 270 | WP_074194493.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|