MGE detailed information
MGE type: Conjugative plasmid MGE length: 137368 bp
Accession: NZ_CP045523 Location: 1..137368 Organism: Shigella flexneri strain 5908.2 Replicon: plasmid p5908-2
Accession: NZ_CP045523 Location: 1..137368 Organism: Shigella flexneri strain 5908.2 Replicon: plasmid p5908-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GE167_RS22970 (1) | 1..1103 | - | 1103 | WP_000527425.1 | shufflon system plasmid conjugative transfer pilus tip adhesin PilV | - |
| GE167_RS24525 (1091) | 1091..1743 | - | 653 | Protein_1 | prepilin peptidase | - |
| GE167_RS22975 (1784) | 1784..2205 | - | 422 | Protein_2 | lytic transglycosylase domain-containing protein | - |
| GE167_RS22980 (2295) | 2295..2909 | - | 615 | WP_000908227.1 | hypothetical protein | VF |
| GE167_RS22985 (2926) | 2926..4012 | - | 1087 | Protein_4 | hypothetical protein | VF |
| GE167_RS24530 (4025) | 4025..4228 | - | 204 | WP_254000271.1 | hypothetical protein | VF |
| GE167_RS24535 (4521) | 4521..4913 | - | 393 | WP_254000272.1 | putative type II secretion system protein HxcR | VF |
| GE167_RS24540 (4913) | 4913..5413 | - | 501 | WP_254000273.1 | hypothetical protein | VF |
| GE167_RS24545 (5424) | 5424..5591 | - | 168 | WP_001442750.1 | type IV pilus biogenesis protein PilP | - |
| GE167_RS24550 (5860) | 5860..6273 | - | 414 | WP_254000277.1 | type 4b pilus protein PilO2 | - |
| GE167_RS23000 (6186) | 6186..7148 | - | 963 | WP_254000274.1 | type 4b pilus protein PilO2 | - |
| GE167_RS23005 (7141) | 7141..8556 | - | 1416 | WP_254000278.1 | Outer membrane lipoprotein BfpB | VF |
| GE167_RS24555 (8465) | 8465..8824 | - | 360 | WP_254000275.1 | hypothetical protein | - |
| GE167_RS24560 (8838) | 8838..9002 | - | 165 | WP_244581202.1 | type IV pilus biogenesis protein PilM | - |
| GE167_RS24565 (9037) | 9037..9276 | - | 240 | WP_254000276.1 | hypothetical protein | - |
| GE167_RS23015 (9276) | 9276..10343 | - | 1068 | WP_001360287.1 | hypothetical protein | VF |
| GE167_RS23020 (11390) | 11390..11644 | - | 255 | WP_001136187.1 | PilI type IV pilus biogenesis protein | - |
| GE167_RS23025 (11816) | 11816..12499 | - | 684 | WP_000213862.1 | conjugal transfer protein TraC | - |
| GE167_RS23030 (12754) | 12754..13287 | - | 534 | WP_001372168.1 | transcription termination/antitermination NusG family protein | - |
| GE167_RS23035 (13729) | 13729..14016 | - | 288 | WP_000074855.1 | conjugal transfer protein TraA | - |
| GE167_RS23040 (13934) | 13934..14159 | - | 226 | Protein_20 | ash family protein | - |
| GE167_RS23045 (15171) | 15171..16202 | + | 1032 | WP_000907869.1 | plasmid replication initiator RepA | - |
| GE167_RS23055 (17112) | 17112..17381 | + | 270 | WP_000079941.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| GE167_RS23060 (17381) | 17381..17653 | + | 273 | WP_254000279.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| GE167_RS23065 (17693) | 17693..18541 | + | 849 | WP_001057996.1 | 3'-5' exonuclease | - |
| GE167_RS23070 (18749) | 18749..19132 | + | 384 | WP_001372421.1 | hypothetical protein | - |
| GE167_RS23985 (19609) | 19609..19875 | - | 267 | WP_000955263.1 | hypothetical protein | - |
| GE167_RS23075 (19875) | 19875..20369 | - | 495 | WP_001459505.1 | hypothetical protein | - |
| GE167_RS23080 (20425) | 20425..21027 | - | 603 | WP_000517695.1 | ProQ/FINO family protein | - |
| GE167_RS23085 (21398) | 21398..22102 | - | 705 | WP_001067858.1 | Tn3 family transposase ISPsy42 | Transposase |
| GE167_RS23090 (22169) | 22169..22453 | + | 285 | Protein_30 | Tn3 family transposase ISPsy42 | Transposase |
| GE167_RS23095 (22800) | 22800..23812 | - | 1013 | Protein_31 | class 1 integron integrase IntI1 | - |
| GE167_RS23100 (23972) | 23972..24445 | + | 474 | WP_000777555.1 | Dihydrofolate reductase type 1 | ARG |
| GE167_RS23105 (24538) | 24538..25376 | + | 839 | Protein_33 | Streptomycin 3''-adenylyltransferase | ARG |
| GE167_RS23110 (25493) | 25493..25840 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| GE167_RS23115 (25834) | 25834..26070 | + | 237 | Protein_35 | dihydropteroate synthase | - |
| GE167_RS23120 (26165) | 26165..26869 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| GE167_RS23125 (26922) | 26922..27515 | + | 594 | Protein_37 | class A beta-lactamase | - |
| GE167_RS23130 (27669) | 27669..30041 | + | 2373 | Protein_38 | Tn3-like element TnAs1 family transposase | - |
| GE167_RS23135 (30075) | 30075..30347 | + | 273 | Protein_39 | IS91 family transposase ISVsa3 | Transposase |
| GE167_RS23145 (30583) | 30583..30825 | - | 243 | Protein_40 | phosphoglucosamine mutase | - |
| GE167_RS23150 (30912) | 30912..31727 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| GE167_RS23155 (31943) | 31943..32647 | - | 705 | WP_001067858.1 | ISKra4 family transposase ISKpn19 | Transposase |
| GE167_RS23160 (32711) | 32711..33226 | + | 516 | Protein_43 | ISKra4 family transposase ISKpn19 | Transposase |
| GE167_RS23165 (33259) | 33259..33687 | + | 429 | Protein_44 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| GE167_RS23170 (34006) | 34006..34662 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| GE167_RS23175 (35057) | 35057..36072 | + | 1016 | Protein_46 | IS3 family transposase ISEc36 | Transposase |
| GE167_RS23180 (36115) | 36115..38898 | - | 2784 | Protein_47 | Tn3 family transposase TnpA_Tn3 | Transposase |
| GE167_RS23185 (38963) | 38963..39256 | + | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| GE167_RS23190 (39303) | 39303..40178 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| GE167_RS23195 (40327) | 40327..40494 | + | 168 | Protein_50 | serine hydrolase | - |
| GE167_RS23990 (40731) | 40731..41033 | - | 303 | WP_001245884.1 | hypothetical protein | - |
| GE167_RS23205 (41030) | 41030..41656 | - | 627 | WP_000587689.1 | ParA family plasmid-partitioning AAA ATPase | - |
| GE167_RS23210 (41860) | 41860..43131 | - | 1272 | WP_000457515.1 | Y-family DNA polymerase | - |
| GE167_RS23215 (43131) | 43131..43568 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| GE167_RS23220 (43565) | 43565..43813 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| GE167_RS23225 (44208) | 44208..45134 | + | 927 | WP_001134370.1 | DUF1281 domain-containing protein | - |
| GE167_RS23230 (45131) | 45131..45442 | + | 312 | WP_001310011.1 | hypothetical protein | - |
| GE167_RS23235 (45519) | 45519..46202 | + | 684 | WP_000086153.1 | DNA methylase | - |
| GE167_RS23240 (46203) | 46203..46424 | + | 222 | WP_001104879.1 | hypothetical protein | - |
| GE167_RS23245 (46438) | 46438..46872 | + | 435 | WP_000274412.1 | DUF1380 family protein | - |
| GE167_RS24570 (46918) | 46918..47694 | + | 777 | WP_001005022.1 | hypothetical protein | - |
| GE167_RS23260 (48108) | 48108..48533 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| GE167_RS23265 (48580) | 48580..49002 | + | 423 | WP_000271745.1 | DUF1380 family protein | - |
| GE167_RS23270 (48999) | 48999..49190 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| GE167_RS23275 (49261) | 49261..49575 | + | 315 | WP_005112260.1 | hypothetical protein | - |
| GE167_RS23280 (50611) | 50611..52512 | + | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| GE167_RS23285 (52662) | 52662..53147 | + | 486 | WP_031222835.1 | single-stranded DNA-binding protein | - |
| GE167_RS23290 (53205) | 53205..53438 | + | 234 | WP_000006020.1 | DUF905 domain-containing protein | - |
| GE167_RS23295 (53497) | 53497..55455 | + | 1959 | WP_001145488.1 | ParB/RepB/Spo0J family partition protein | - |
| GE167_RS23300 (55510) | 55510..55944 | + | 435 | WP_001387500.1 | conjugation system SOS inhibitor PsiB | - |
| GE167_RS23305 (55941) | 55941..56660 | + | 720 | WP_001276270.1 | plasmid SOS inhibition protein A | - |
| GE167_RS23310 (56657) | 56657..57253 | + | 597 | WP_000977995.1 | hypothetical protein | - |
| GE167_RS23320 (57715) | 57715..58215 | + | 501 | WP_000117611.1 | antirestriction protein ArdA | - |
| GE167_RS23325 (58944) | 58944..59378 | + | 435 | WP_000218858.1 | hypothetical protein | - |
| GE167_RS23330 (59472) | 59472..59738 | + | 267 | WP_000804663.1 | hypothetical protein | - |
| GE167_RS23335 (59915) | 59915..60304 | + | 390 | WP_000833767.1 | hypothetical protein | - |
| GE167_RS23340 (60301) | 60301..61215 | + | 915 | WP_000038348.1 | Recombination-promoting nuclease RpnA | VF |
| GE167_RS23345 (61277) | 61277..61483 | + | 207 | WP_000150314.1 | hypothetical protein | VF |
| GE167_RS23350 (61514) | 61514..61765 | - | 252 | WP_000148285.1 | helix-turn-helix transcriptional regulator | - |
| GE167_RS23355 (62345) | 62345..63193 | + | 849 | WP_001077053.1 | DUF4942 domain-containing protein | - |
| GE167_RS23360 (63280) | 63280..63615 | - | 336 | WP_000157095.1 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| GE167_RS23365 (63849) | 63849..64181 | + | 333 | WP_001283947.1 | IncI1-type relaxosome accessory protein NikA | - |
| GE167_RS23370 (64192) | 64192..66891 | + | 2700 | WP_001387486.1 | Protein TraI | Relaxase |
| GE167_RS23375 (66928) | 66928..69219 | - | 2292 | WP_001289278.1 | F-type conjugative transfer protein TrbC | - |
| GE167_RS23380 (69212) | 69212..70282 | - | 1071 | WP_000151588.1 | IncI1-type conjugal transfer protein TrbB | - |
| GE167_RS23385 (70301) | 70301..71509 | - | 1209 | WP_000121263.1 | hypothetical protein | VF |
| GE167_RS23390 (71816) | 71816..72901 | - | 1086 | WP_000080543.1 | protein finQ | - |
| - (73110) | 73110..73172 | - | 63 | NuclAT_0 | - | - |
| - (73110) | 73110..73172 | - | 63 | NuclAT_0 | - | - |
| - (73110) | 73110..73172 | - | 63 | NuclAT_0 | - | - |
| - (73110) | 73110..73172 | - | 63 | NuclAT_0 | - | - |
| GE167_RS23395 (73222) | 73222..73374 | + | 153 | WP_001387489.1 | Hok/Gef family protein | Toxin Detail |
| GE167_RS23400 (73446) | 73446..73697 | - | 252 | WP_001291964.1 | hypothetical protein | - |
| GE167_RS23405 (73997) | 73997..74293 | + | 297 | WP_001275298.1 | DinQ-like type I toxin DqlB | - |
| GE167_RS24000 (74358) | 74358..74534 | - | 177 | WP_001054898.1 | hypothetical protein | - |
| GE167_RS23410 (74717) | 74717..74926 | - | 210 | WP_001140543.1 | hemolysin expression modulator Hha | - |
| GE167_RS23415 (75024) | 75024..75638 | - | 615 | WP_000578648.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| GE167_RS23420 (75714) | 75714..77882 | - | 2169 | WP_000698360.1 | IncI1-type conjugal transfer membrane protein TraY | - |
| GE167_RS23425 (77979) | 77979..78563 | - | 585 | WP_001037983.1 | IncI1-type conjugal transfer protein TraX | - |
| GE167_RS23430 (78592) | 78592..79794 | - | 1203 | WP_001387490.1 | IncI1-type conjugal transfer protein TraW | - |
| GE167_RS23435 (79761) | 79761..80375 | - | 615 | WP_000337395.1 | IncI1-type conjugal transfer protein TraV | - |
| GE167_RS23440 (80375) | 80375..83419 | - | 3045 | WP_001024789.1 | IncI1-type conjugal transfer protein TraU | - |
| GE167_RS23445 (83509) | 83509..84309 | - | 801 | WP_001164783.1 | IncI1-type conjugal transfer protein TraT | - |
| GE167_RS23450 (84293) | 84293..84481 | - | 189 | WP_001277253.1 | putative conjugal transfer protein TraS | - |
| GE167_RS23455 (84545) | 84545..84949 | - | 405 | WP_000086965.1 | IncI1-type conjugal transfer protein TraR | - |
| GE167_RS23460 (85000) | 85000..85527 | - | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| GE167_RS23465 (85527) | 85527..86231 | - | 705 | WP_000801920.1 | IncI1-type conjugal transfer protein TraP | - |
| GE167_RS23470 (86231) | 86231..87520 | - | 1290 | WP_001271994.1 | conjugal transfer protein TraO | - |
| GE167_RS23475 (87523) | 87523..88506 | - | 984 | WP_001191879.1 | hypothetical protein | VF |
| GE167_RS23480 (88517) | 88517..89008 | - | 492 | WP_244579706.1 | DotI/IcmL family type IV secretion protein | - |
| GE167_RS23485 (89206) | 89206..89553 | - | 348 | WP_001055900.1 | conjugal transfer protein | - |
| GE167_RS23490 (89571) | 89571..93335 | - | 3765 | WP_001141540.1 | DUF5710 domain-containing protein | - |
| GE167_RS23495 (93425) | 93425..93976 | - | 552 | WP_000014586.1 | Phospholipase D | VF |
| GE167_RS23500 (93991) | 93991..94281 | - | 291 | WP_001314267.1 | hypothetical protein | - |
| GE167_RS23505 (94278) | 94278..95426 | - | 1149 | WP_001024972.1 | putative protein YggR | VF |
| GE167_RS23510 (95423) | 95423..96241 | - | 819 | WP_000646098.1 | hypothetical protein | VF |
| GE167_RS23515 (96238) | 96238..96696 | - | 459 | WP_001079808.1 | hypothetical protein | VF |
| GE167_RS23520 (97091) | 97091..97675 | - | 585 | WP_000977522.1 | histidine phosphatase family protein | - |
| GE167_RS23525 (97735) | 97735..98937 | - | 1203 | WP_000976357.1 | conjugal transfer protein TraF | - |
| GE167_RS23530 (99023) | 99023..99847 | - | 825 | WP_001238932.1 | conjugal transfer protein TraE | - |
| GE167_RS23535 (99998) | 99998..101152 | - | 1155 | WP_001139956.1 | site-specific integrase | - |
| GE167_RS23540 (102786) | 102786..104222 | - | 1437 | WP_000527428.1 | hypothetical protein | VF |
| GE167_RS23545 (104210) | 104210..104866 | - | 657 | WP_001193549.1 | hypothetical protein | VF |
| GE167_RS23550 (104851) | 104851..105411 | - | 561 | WP_000014005.1 | hypothetical protein | VF |
| GE167_RS23555 (105421) | 105421..106035 | - | 615 | WP_000908227.1 | hypothetical protein | VF |
| GE167_RS23560 (106052) | 106052..107137 | - | 1086 | WP_001208802.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| GE167_RS23565 (107150) | 107150..108703 | - | 1554 | WP_000362206.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| GE167_RS23570 (108714) | 108714..109166 | - | 453 | WP_001247337.1 | hypothetical protein | VF |
| GE167_RS23575 (109153) | 109153..110448 | - | 1296 | WP_000752782.1 | type 4b pilus protein PilO2 | - |
| GE167_RS23580 (110441) | 110441..112123 | - | 1683 | WP_000748144.1 | Outer membrane lipoprotein BfpB | VF |
| GE167_RS23585 (112137) | 112137..112574 | - | 438 | WP_000539806.1 | hypothetical protein | VF |
| GE167_RS23590 (112574) | 112574..113641 | - | 1068 | WP_001360287.1 | hypothetical protein | VF |
| GE167_RS23595 (114688) | 114688..114942 | - | 255 | WP_001136187.1 | PilI type IV pilus biogenesis protein | - |
| GE167_RS23600 (115114) | 115114..115797 | - | 684 | WP_000213862.1 | conjugal transfer protein TraC | - |
| GE167_RS23605 (116051) | 116051..116581 | - | 531 | WP_161550650.1 | transcription termination/antitermination NusG family protein | - |
| GE167_RS23610 (117028) | 117028..117309 | - | 282 | Protein_132 | conjugal transfer protein TraA | - |
| GE167_RS24575 (117347) | 117347..117505 | - | 159 | Protein_133 | ash family protein | - |
| GE167_RS23620 (118463) | 118463..119495 | + | 1033 | Protein_134 | replication initiation protein | - |
| GE167_RS23630 (120405) | 120405..120674 | + | 270 | WP_000079941.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| GE167_RS23635 (120674) | 120674..120952 | + | 279 | WP_244442846.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| GE167_RS23640 (120992) | 120992..121840 | + | 849 | WP_001057996.1 | 3'-5' exonuclease | - |
| GE167_RS23645 (121957) | 121957..122430 | + | 474 | WP_001334658.1 | hypothetical protein | - |
| GE167_RS24010 (122908) | 122908..123174 | - | 267 | WP_173020741.1 | hypothetical protein | - |
| GE167_RS24580 (123174) | 123174..123666 | - | 493 | Protein_140 | hypothetical protein | - |
| GE167_RS23655 (123721) | 123721..124314 | - | 594 | WP_161550651.1 | ProQ/FINO family protein | - |
| GE167_RS23660 (124685) | 124685..125389 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| GE167_RS23665 (125455) | 125455..125739 | + | 285 | Protein_143 | recombinase family protein | - |
| GE167_RS23670 (126084) | 126084..127097 | - | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| GE167_RS23675 (127254) | 127254..127727 | + | 474 | WP_000777555.1 | Dihydrofolate reductase type 1 | ARG |
| GE167_RS23680 (127820) | 127820..128658 | + | 839 | Protein_146 | Streptomycin 3''-adenylyltransferase | ARG |
| GE167_RS23685 (128769) | 128769..129116 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| GE167_RS23690 (129110) | 129110..129346 | + | 237 | Protein_148 | dihydropteroate synthase | - |
| GE167_RS23695 (129441) | 129441..130145 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| GE167_RS23700 (130198) | 130198..130792 | + | 595 | Protein_150 | class A beta-lactamase | - |
| GE167_RS23705 (130947) | 130947..133313 | + | 2367 | Protein_151 | Tn3 family transposase | - |
| GE167_RS23710 (133347) | 133347..133619 | + | 273 | Protein_152 | IS91 family transposase ISVsa3 | Transposase |
| GE167_RS23720 (133855) | 133855..134097 | - | 243 | Protein_153 | phosphoglucosamine mutase | - |
| GE167_RS23725 (134184) | 134184..134999 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| GE167_RS23730 (135215) | 135215..135921 | - | 707 | Protein_155 | ISKra4 family transposase ISKpn19 | Transposase |
| GE167_RS23735 (135985) | 135985..136500 | + | 516 | Protein_156 | ISKra4 family transposase ISKpn19 | Transposase |
| GE167_RS23740 (136533) | 136533..136960 | + | 428 | Protein_157 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| GE167_RS23745 (137080) | 137080..137368 | - | 289 | Protein_158 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|