NZ_CP0442591..144422

MGE detailed information

MGE type: Mobilizable plasmid        MGE length: 144422 bp
Accession: NZ_CP044259        Location: 1..144422         Organism: Klebsiella pneumoniae strain KP65       Replicon: plasmid pKPC-2-KP65


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6W81_RS27125 () 1..858 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
F6W81_RS27135 () 1797..2450 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
F6W81_RS27140 () 2543..2800 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
F6W81_RS27145 () 2733..3134 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
F6W81_RS27150 () 3383..3798 + 416 Protein_5 IS1 family transposase IS1R Transposase
F6W81_RS27155 () 3834..4379 - 546 Protein_6 Tn3 family transposase TnpA_Tn3 Transposase
F6W81_RS27160 () 4445..5149 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27165 () 5219..5410 + 192 Protein_8 transposase -
F6W81_RS27170 () 5660..6535 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
F6W81_RS27175 () 6570..7538 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
F6W81_RS27180 () 7595..8692 + 1098 Protein_11 TonB-dependent receptor -
F6W81_RS27185 () 8760..9209 - 450 Protein_12 PAS domain-containing protein -
F6W81_RS27190 () 9289..9993 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27195 () 10058..10648 + 591 Protein_14 IS91 family transposase ISSbo1 Transposase
F6W81_RS27205 () 11104..11808 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27215 () 11874..12392 + 519 WP_014839979.1 hypothetical protein -
F6W81_RS27220 () 12397..12813 - 417 WP_014839980.1 Glutathione transferase FosA ARG
F6W81_RS27225 () 13199..13903 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27230 () 13954..14571 - 618 Protein_19 IS91 family transposase ISSbo1 Transposase
F6W81_RS27235 () 14581..14769 - 189 WP_000957857.1 hypothetical protein -
F6W81_RS27240 () 14861..15397 + 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
F6W81_RS27245 () 15580..16440 + 861 WP_000027057.1 Beta-lactamase TEM ARG
F6W81_RS27250 () 16610..17365 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
F6W81_RS27255 () 17446..17727 - 282 WP_015059004.1 sodium/hydrogen exchanger -
F6W81_RS27260 () 17815..18519 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
F6W81_RS27265 () 18585..19562 + 978 Protein_26 Multifunctional conjugation protein TraI Relaxase
F6W81_RS28930 () 19596..19754 - 159 Protein_27 IS6 family transposase IS15DI Transposase
F6W81_RS27270 () 19807..20511 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27275 () 20548..21207 - 660 WP_191904780.1 IS6 family transposase IS26 Transposase
F6W81_RS27285 () 21271..21546 - 276 Protein_30 PAS domain-containing protein -
F6W81_RS27290 () 21621..22325 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27300 () 22379..22675 + 297 Protein_32 peptidase -
F6W81_RS27305 () 22675..23946 + 1272 WP_013214011.1 Y-family DNA polymerase -
F6W81_RS27310 () 24028..25002 - 975 WP_011977819.1 ParB/RepB/Spo0J family partition protein -
F6W81_RS27315 () 25002..26207 - 1206 WP_011977818.1 AAA family ATPase -
F6W81_RS27330 () 27317..28183 - 867 WP_004118283.1 replication initiation protein -
F6W81_RS28935 () 28719..28832 + 114 WP_014343462.1 hypothetical protein -
F6W81_RS27335 () 28961..29218 + 258 WP_013214010.1 hypothetical protein -
F6W81_RS27340 () 29264..30043 - 780 WP_013214009.1 site-specific integrase -
F6W81_RS27345 () 30227..31231 - 1005 WP_011977814.1 hypothetical protein -
F6W81_RS27350 () 31261..31464 - 204 WP_011977813.1 hypothetical protein -
F6W81_RS27355 () 31611..32315 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27360 () 32374..32520 - 147 Protein_43 peptidase -
F6W81_RS27370 () 32927..34414 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
F6W81_RS27375 () 34663..35634 + 972 WP_004152353.1 mediator of plasmid stability -
F6W81_RS27380 () 35637..36308 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
F6W81_RS27385 () 36371..36601 + 231 WP_001568040.1 hypothetical protein -
F6W81_RS27390 () 37038..37739 + 702 WP_001568041.1 DNA methylase -
F6W81_RS27395 () 37739..37960 + 222 WP_001568042.1 hypothetical protein -
F6W81_RS27400 () 37970..38389 + 420 WP_001568043.1 DUF1380 domain-containing protein -
F6W81_RS27405 () 38443..39210 + 768 WP_013214013.1 hypothetical protein -
F6W81_RS27410 () 39891..40319 + 429 WP_001568045.1 antirestriction protein -
F6W81_RS27415 () 40362..40868 + 507 WP_013214014.1 antirestriction protein ArdA -
F6W81_RS27420 () 40911..41102 + 192 WP_001568047.1 hypothetical protein -
F6W81_RS27425 () 41290..41544 + 255 WP_011977779.1 DNA polymerase III subunit theta -
F6W81_RS27430 () 41579..41899 + 321 WP_001568049.1 hypothetical protein -
F6W81_RS27445 () 42579..42806 + 228 WP_001568050.1 hypothetical protein -
F6W81_RS27450 () 42898..43128 + 231 WP_001568051.1 hypothetical protein -
F6W81_RS27455 () 43180..44535 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
F6W81_RS27460 () 44583..45146 + 564 WP_014343514.1 methyltransferase -
F6W81_RS27480 () 45979..46521 + 543 WP_014343512.1 single-stranded DNA-binding protein -
F6W81_RS27485 () 46570..46818 + 249 WP_001568055.1 DUF905 domain-containing protein -
F6W81_RS27490 () 46888..48945 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
F6W81_RS27495 () 48990..49421 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
F6W81_RS27500 () 49418..50146 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
F6W81_RS27505 () 50143..50469 + 327 WP_013023807.1 hypothetical protein -
F6W81_RS27510 () 50525..50899 + 375 WP_014343510.1 hypothetical protein -
F6W81_RS27520 () 51127..51285 + 159 WP_014343509.1 type I toxin-antitoxin system Hok family toxin -
F6W81_RS27530 () 51978..52250 + 273 WP_040245921.1 hypothetical protein -
F6W81_RS27535 () 52247..52597 + 351 WP_040245917.1 hypothetical protein -
F6W81_RS27540 () 52612..52929 + 318 WP_014343505.1 hypothetical protein -
F6W81_RS27550 () 53770..54126 + 357 WP_014343501.1 hypothetical protein -
F6W81_RS27555 () 54187..54399 + 213 WP_014343500.1 hypothetical protein -
F6W81_RS27560 () 54410..54634 + 225 WP_014343499.1 hypothetical protein -
F6W81_RS27565 () 54715..55035 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
F6W81_RS27570 () 55025..55303 + 279 WP_004152721.1 helix-turn-helix domain-containing protein -
F6W81_RS27595 () 56240..57061 + 822 WP_004152492.1 DUF945 domain-containing protein -
F6W81_RS27600 () 57094..57423 + 330 WP_013214015.1 hypothetical protein -
F6W81_RS27605 () 57456..57941 - 486 WP_014343495.1 hypothetical protein VF
F6W81_RS27610 () 58332..58748 + 417 WP_014343494.1 relaxosome protein TraM -
F6W81_RS27615 () 58948..59685 + 738 WP_013214018.1 conjugal transfer protein TrbJ -
F6W81_RS27620 () 59800..60006 + 207 WP_171773970.1 TraY domain-containing protein -
F6W81_RS27625 () 60068..60436 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
F6W81_RS27630 () 60450..60755 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
F6W81_RS27635 () 60775..61092 + 318 Protein_85 hypothetical protein -
F6W81_RS27640 () 61145..61849 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
F6W81_RS27645 () 61840..61980 + 141 WP_071557810.1 hypothetical protein -
F6W81_RS27660 () 63429..63663 + 235 Protein_88 type II toxin-antitoxin system RelE/ParE family toxin -
F6W81_RS27665 () 63791..64072 + 282 WP_001333089.1 hypothetical protein -
F6W81_RS27670 () 64195..64545 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
F6W81_RS27675 () 64548..65510 - 963 WP_000959884.1 plasmid segregation protein ParM -
F6W81_RS27680 () 65657..65950 + 294 WP_032146011.1 hypothetical protein -
F6W81_RS27690 () 66027..66710 + 684 WP_000085883.1 DNA methylase -
F6W81_RS27695 () 66711..66932 + 222 WP_001104881.1 hypothetical protein -
F6W81_RS27700 () 66946..67380 + 435 WP_000274503.1 DUF1380 family protein -
F6W81_RS28940 () 67431..68207 + 777 WP_001383963.1 hypothetical protein -
F6W81_RS27715 () 68625..69050 + 426 WP_001198928.1 antirestriction protein -
F6W81_RS27720 () 69097..69519 + 423 WP_000271762.1 DUF1380 family protein -
F6W81_RS27725 () 69516..69707 + 192 WP_001027493.1 hypothetical protein -
F6W81_RS27730 () 70021..71688 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
F6W81_RS27740 () 73088..73318 + 231 WP_000218642.1 hypothetical protein -
F6W81_RS27745 () 73370..74731 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
F6W81_RS27750 () 74778..75341 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
F6W81_RS27775 () 76184..76711 + 528 WP_000290834.1 single-stranded DNA-binding protein -
F6W81_RS27780 () 76769..77002 + 234 WP_000006003.1 DUF905 family protein -
F6W81_RS27785 () 77063..79086 + 2024 Protein_106 ParB/RepB/Spo0J family partition protein -
F6W81_RS27790 () 79155..79589 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
F6W81_RS27795 () 79586..80305 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- () 80317..80541 + 225 NuclAT_0 - -
- () 80317..80541 + 225 NuclAT_0 - -
- () 80317..80541 + 225 NuclAT_0 - -
- () 80317..80541 + 225 NuclAT_0 - -
F6W81_RS27800 () 80585..80743 + 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
F6W81_RS28945 () 80981..81358 - 378 Protein_110 hypothetical protein -
F6W81_RS27820 () 81658..81954 + 297 WP_001272251.1 hypothetical protein -
F6W81_RS27825 () 82065..82886 + 822 WP_001234445.1 DUF945 domain-containing protein -
F6W81_RS27830 () 83183..83830 - 648 WP_015059008.1 hypothetical protein VF
F6W81_RS27835 () 84107..84490 + 384 WP_000124981.1 relaxosome protein TraM -
F6W81_RS27840 () 84681..85367 + 687 WP_015059009.1 PAS domain-containing protein -
F6W81_RS27845 () 85461..85688 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
F6W81_RS27850 () 85722..86087 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
F6W81_RS27855 () 86102..86413 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
F6W81_RS27860 () 86435..87001 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
F6W81_RS27870 () 87197..87901 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
F6W81_RS27875 () 87964..88530 + 567 Protein_121 replication protein -
F6W81_RS27880 () 89064..89342 + 279 WP_013213990.1 hypothetical protein -
F6W81_RS27885 () 89453..89878 + 426 WP_013213989.1 antirestriction protein -
F6W81_RS28950 () 90006..90161 + 156 WP_013213988.1 hypothetical protein -
F6W81_RS27890 () 90207..90503 + 297 WP_013213987.1 transcriptional regulator -
F6W81_RS27895 () 90607..91194 + 588 Protein_126 IS1182 family transposase ISKpn6 Transposase
F6W81_RS27905 () 91246..91950 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27910 () 92011..92316 + 306 Protein_128 IS1182 family transposase ISKpn6 Transposase
F6W81_RS27915 () 92566..93447 - 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
F6W81_RS27920 () 93723..94703 - 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
F6W81_RS27925 () 94826..95287 - 462 Protein_131 Tn3 family transposase TnpR_Tn3 Transposase
F6W81_RS27935 () 95339..96043 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS27940 () 96108..97280 - 1173 Protein_133 transposase -
F6W81_RS27950 () 97355..98023 - 669 WP_001300294.1 putative signaling protein VF
F6W81_RS27955 () 98059..98295 - 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
F6W81_RS27960 () 98292..98654 - 363 WP_001277456.1 mercury resistance co-regulator MerD -
F6W81_RS27965 () 98672..100366 - 1695 WP_000105636.1 mercury(II) reductase -
F6W81_RS27970 () 100418..100840 - 423 WP_001340589.1 organomercurial transporter MerC -
F6W81_RS27975 () 100876..101151 - 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
F6W81_RS27980 () 101165..101515 - 351 WP_001294663.1 mercuric transport protein MerT -
F6W81_RS27985 () 101587..102021 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
F6W81_RS27990 () 102100..103104 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
F6W81_RS27995 () 103286..103462 - 177 WP_000954592.1 Arm DNA-binding domain-containing protein -
F6W81_RS28000 () 103584..103808 - 225 WP_000743213.1 hypothetical protein -
F6W81_RS28005 () 103805..104542 - 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
F6W81_RS28955 () 105028..105168 - 141 WP_001044210.1 hypothetical protein -
F6W81_RS28015 () 105174..105878 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS28020 () 106347..106904 - 558 WP_042934582.1 hypothetical protein -
F6W81_RS28025 () 107032..107409 - 378 Protein_149 restriction endonuclease -
F6W81_RS28030 () 107556..108536 - 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
F6W81_RS28035 () 108605..108997 + 393 Protein_151 3'-5' exonuclease -
F6W81_RS28040 () 109050..109445 + 396 WP_015493087.1 hypothetical protein -
F6W81_RS28045 () 109442..110053 + 612 WP_015493086.1 DUF2913 family protein -
F6W81_RS28050 () 110050..111000 - 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
F6W81_RS28055 () 111147..111347 - 201 WP_040219232.1 hypothetical protein -
F6W81_RS28060 () 111401..112033 - 633 WP_022652286.1 Tn3 family transposase TnpR_TnEc1 Transposase
F6W81_RS28065 () 112396..113601 + 1206 WP_015493083.1 Plasmid partition protein A VF
F6W81_RS28070 () 113598..114569 + 972 WP_016479949.1 ParB/RepB/Spo0J family partition protein -
F6W81_RS28080 () 114705..115976 - 1272 WP_015493081.1 Y-family DNA polymerase -
F6W81_RS28085 () 115976..116398 - 423 WP_015493080.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
F6W81_RS28090 () 116578..117249 - 672 WP_015493079.1 SOS response-associated peptidase family protein -
F6W81_RS28095 () 117608..118285 + 678 WP_002211749.1 DNA methylase -
F6W81_RS28100 () 118285..118506 + 222 WP_015493077.1 hypothetical protein -
F6W81_RS28105 () 118517..118936 + 420 WP_015493076.1 DUF1380 domain-containing protein -
F6W81_RS28110 () 118990..119769 + 780 WP_015493075.1 hypothetical protein -
F6W81_RS28115 () 120174..120680 + 507 WP_015493074.1 antirestriction protein ArdA -
F6W81_RS28120 () 120723..120914 + 192 WP_015493073.1 hypothetical protein -
F6W81_RS28125 () 121107..121361 + 255 WP_015493072.1 DNA polymerase III subunit theta -
F6W81_RS28130 () 121396..121713 + 318 Protein_169 hypothetical protein -
F6W81_RS28135 () 122339..122569 + 231 WP_015493071.1 DUF905 domain-containing protein -
F6W81_RS28140 () 122640..124649 + 2010 Protein_171 ParB/RepB/Spo0J family partition protein -
F6W81_RS28145 () 124692..125123 + 432 WP_008324186.1 conjugation system SOS inhibitor PsiB -
F6W81_RS28150 () 125120..125848 + 729 WP_008324185.1 plasmid SOS inhibition protein A -
F6W81_RS28155 () 125845..126168 + 324 WP_008324183.1 hypothetical protein -
F6W81_RS28160 () 126230..126589 + 360 WP_015493069.1 hypothetical protein -
F6W81_RS28165 () 127215..127589 + 375 WP_008324180.1 hypothetical protein -
F6W81_RS28170 () 127715..128419 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS28175 () 128591..129535 - 945 WP_011977810.1 hypothetical protein -
F6W81_RS28180 () 129696..130157 - 462 WP_014343465.1 hypothetical protein -
F6W81_RS28185 () 130114..130344 + 231 WP_001261282.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
F6W81_RS28190 () 130341..130757 + 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
F6W81_RS28195 () 130831..132393 + 1563 WP_004206609.1 AAA family ATPase -
F6W81_RS28200 () 132378..133400 + 1023 WP_000361404.1 helicase UvrD -
F6W81_RS28205 () 133656..134353 + 698 Protein_184 IS1 family transposase ISKpn14 Transposase
F6W81_RS28210 () 134382..134654 + 273 Protein_185 IS5 family transposase ISPan1 Transposase
F6W81_RS28215 () 134934..135938 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
F6W81_RS28220 () 136017..138983 - 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
F6W81_RS28225 () 138986..139051 - 66 Protein_188 helix-turn-helix domain-containing protein -
F6W81_RS28230 () 139104..139808 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
F6W81_RS28235 () 139872..140033 + 162 Protein_190 DNA helicase -
F6W81_RS28240 () 140053..140799 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
F6W81_RS28245 () 140854..141414 + 561 WP_000139328.1 fertility inhibition protein FinO -
F6W81_RS28250 () 141546..141746 + 201 WP_015059022.1 hypothetical protein -
F6W81_RS28255 () 142132..142731 + 600 WP_032083981.1 hypothetical protein -
F6W81_RS28260 () 142895..143125 + 231 WP_001736714.1 hypothetical protein -
- () 143326..143385 - 60 NuclAT_1 - Antitoxin Detail
- () 143326..143385 - 60 NuclAT_1 - Antitoxin Detail
- () 143326..143385 - 60 NuclAT_1 - Antitoxin Detail
- () 143326..143385 - 60 NuclAT_1 - Antitoxin Detail
F6W81_RS28270 () 143430..143579 + 150 WP_001312851.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
F6W81_RS28275 () 143863..144111 + 249 WP_000083837.1 replication regulatory protein RepA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance