MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 146462 bp
Accession: NZ_CP044160 Location: 1..146462 Organism: Shigella flexneri strain AR-0423 Replicon: plasmid pAR-0423-2
Accession: NZ_CP044160 Location: 1..146462 Organism: Shigella flexneri strain AR-0423 Replicon: plasmid pAR-0423-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| F4V35_RS24160 | 399..590 | + | 192 | WP_000829592.1 | hypothetical protein | - |
| F4V35_RS24170 | 2025..2213 | - | 189 | WP_000957853.1 | hypothetical protein | - |
| F4V35_RS24175 | 2359..2514 | + | 156 | Protein_3 | IS256 family transposase | - |
| F4V35_RS24180 | 2544..4271 | - | 1728 | WP_000597731.1 | T3SS effector E3 ubiquitin-protein ligase IpaH1.4 | - |
| F4V35_RS24185 | 4662..4928 | - | 267 | WP_000957716.1 | type 3 secretion system effector OspE1 | - |
| F4V35_RS26020 | 5037..5167 | - | 131 | Protein_6 | IS1 family transposase | - |
| F4V35_RS26025 | 5165..5248 | + | 84 | Protein_7 | IS66 family insertion sequence element accessory protein TnpB | - |
| F4V35_RS24195 | 5767..6290 | + | 524 | Protein_8 | IS3-like element ISSfl11 family transposase | - |
| F4V35_RS24200 | 6333..6671 | - | 339 | Protein_9 | integrase core domain-containing protein | - |
| F4V35_RS24205 | 6745..7727 | + | 983 | Protein_10 | IS3-like element IS911 family transposase | - |
| F4V35_RS24210 | 7818..9046 | + | 1229 | WP_148936977.1 | IS3-like element IS2 family transposase | - |
| F4V35_RS24215 | 9058..9249 | + | 192 | Protein_12 | IS3 family transposase | - |
| F4V35_RS24220 | 9273..9966 | - | 694 | Protein_13 | type III secretion system effector cysteine methyltransferase OspZ | - |
| F4V35_RS24225 | 10022..10174 | + | 153 | Protein_14 | integrase core domain-containing protein | - |
| F4V35_RS25455 | 10456..10593 | - | 138 | WP_011378983.1 | hypothetical protein | - |
| F4V35_RS24230 | 11555..12502 | + | 948 | WP_005061047.1 | omptin family outer membrane protease IcsP | - |
| F4V35_RS24240 | 13064..13436 | - | 373 | Protein_17 | integrase core domain-containing protein | - |
| F4V35_RS24250 | 13680..13799 | + | 120 | Protein_18 | DUF3440 domain-containing protein | - |
| F4V35_RS24255 | 14049..14915 | + | 867 | WP_001046939.1 | type 3 secretion system effector OspB | - |
| F4V35_RS24260 | 15244..15984 | + | 741 | WP_000850662.1 | PAP2 family phosphatase PhoN2 | - |
| F4V35_RS24270 | 16337..17791 | - | 1455 | Protein_21 | type 3 secretion system effector OspC4 | - |
| F4V35_RS24275 | 18158..18676 | - | 519 | Protein_22 | IS66 family transposase zinc-finger binding domain-containing protein | - |
| F4V35_RS24280 | 18693..18929 | - | 237 | Protein_23 | IS3 family transposase | - |
| F4V35_RS24290 | 18980..20136 | - | 1157 | Protein_24 | IS3 family transposase | - |
| F4V35_RS24295 | 20308..22017 | - | 1710 | WP_005061014.1 | ShET2/EspL2 family type III secretion system effector toxin | - |
| F4V35_RS24300 | 22449..23168 | - | 720 | WP_001121867.1 | type III secretion system effector phosphothreonine lyase | - |
| F4V35_RS24305 | 23293..23849 | - | 557 | Protein_27 | transposase | - |
| F4V35_RS24310 | 23833..24091 | + | 259 | Protein_28 | IS1 family transposase | - |
| F4V35_RS24315 | 24200..24778 | - | 579 | WP_000868563.1 | hypothetical protein | - |
| F4V35_RS26030 | 24827..25085 | - | 259 | Protein_30 | integrase core domain-containing protein | - |
| F4V35_RS24320 | 25199..25436 | - | 238 | Protein_31 | ATP-binding protein | - |
| F4V35_RS24325 | 25623..26052 | - | 430 | Protein_32 | transposase | - |
| F4V35_RS24330 | 26130..26417 | + | 288 | WP_001082155.1 | hypothetical protein | - |
| F4V35_RS24335 | 26448..26729 | + | 282 | Protein_34 | IS66 family insertion sequence element accessory protein TnpB | - |
| F4V35_RS24340 | 26743..28089 | - | 1347 | WP_011587243.1 | IS4-like element IS4 family transposase | - |
| F4V35_RS24345 | 28159..28533 | + | 375 | Protein_36 | IS66-like element accessory protein TnpA | - |
| F4V35_RS24350 | 28533..28880 | + | 348 | WP_000622998.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| F4V35_RS24355 | 28900..30129 | + | 1230 | Protein_38 | IS66 family transposase | - |
| F4V35_RS24360 | 30133..30292 | + | 160 | Protein_39 | integrase core domain-containing protein | - |
| F4V35_RS26035 | 30535..30627 | - | 93 | Protein_40 | type III effector | - |
| F4V35_RS24370 | 30881..31179 | + | 299 | Protein_41 | transposase | - |
| F4V35_RS24375 | 31261..31398 | + | 138 | Protein_42 | IS630 family transposase | - |
| F4V35_RS24380 | 31770..32447 | + | 678 | WP_000026470.1 | type 3 secretion system effector/anti-activator OspD1 | - |
| F4V35_RS24390 | 32770..32880 | + | 111 | Protein_44 | IS3 family transposase | - |
| F4V35_RS25460 | 32958..33272 | + | 315 | WP_011114726.1 | hypothetical protein | - |
| F4V35_RS24405 | 33554..34120 | + | 567 | WP_000901798.1 | type III secretion effector IpgB2 | - |
| F4V35_RS26040 | 34382..34504 | - | 123 | Protein_47 | transposase domain-containing protein | - |
| F4V35_RS24415 | 34647..35201 | + | 555 | Protein_48 | IS3-like element IS3H family transposase | - |
| F4V35_RS24420 | 35540..35901 | + | 362 | Protein_49 | IS1 family transposase | - |
| F4V35_RS24425 | 35988..36665 | + | 678 | Protein_50 | IS21 family transposase | - |
| F4V35_RS24430 | 36691..37884 | - | 1194 | WP_005064872.1 | IS4-like element ISSfl1 family transposase | - |
| F4V35_RS24435 | 37964..38320 | + | 357 | Protein_52 | IS21 family transposase | - |
| F4V35_RS24440 | 38317..39099 | + | 783 | WP_011114728.1 | IS21-like element IS100kyp family helper ATPase IstB | - |
| F4V35_RS24445 | 39166..39504 | + | 339 | Protein_54 | IS1 family transposase | - |
| F4V35_RS26045 | 39518..39652 | + | 135 | Protein_55 | hypothetical protein | - |
| F4V35_RS24455 | 39826..41025 | + | 1200 | WP_000200287.1 | AAA family ATPase | - |
| F4V35_RS24460 | 41025..42005 | + | 981 | WP_000431558.1 | ParB family protein | - |
| F4V35_RS24465 | 42261..42746 | + | 486 | WP_000003223.1 | IS110 family transposase | - |
| F4V35_RS24470 | 42773..42952 | - | 180 | Protein_59 | transposase domain-containing protein | - |
| F4V35_RS24475 | 43035..44162 | - | 1128 | WP_014526552.1 | group II intron reverse transcriptase/maturase | - |
| F4V35_RS26050 | 44084..44422 | + | 339 | WP_227804374.1 | hypothetical protein | - |
| F4V35_RS24485 | 44738..44917 | - | 180 | Protein_62 | IS66 family transposase | - |
| F4V35_RS24490 | 44954..46163 | - | 1210 | Protein_63 | IS3 family transposase | - |
| F4V35_RS24495 | 46220..46516 | - | 297 | Protein_64 | DDE-type integrase/transposase/recombinase | - |
| F4V35_RS24500 | 46632..46820 | + | 189 | WP_000957853.1 | hypothetical protein | - |
| F4V35_RS24505 | 46830..48029 | + | 1200 | WP_000947175.1 | IS91 family transposase | - |
| F4V35_RS24510 | 48202..48956 | - | 755 | Protein_67 | helix-turn-helix domain-containing protein | - |
| F4V35_RS24515 | 48967..49326 | + | 360 | Protein_68 | ATP-binding protein | - |
| F4V35_RS24520 | 49319..50107 | - | 789 | WP_005116773.1 | AraC family invasion system transcriptional regulator VirF | - |
| F4V35_RS24525 | 50536..50937 | + | 402 | Protein_70 | integrase core domain-containing protein | - |
| F4V35_RS24530 | 51119..51385 | + | 267 | WP_000957712.1 | type 3 secretion system effector OspE2 | - |
| F4V35_RS24535 | 51575..52272 | + | 698 | WP_227804301.1 | IS1 family transposase | - |
| F4V35_RS24540 | 52533..53729 | - | 1197 | WP_005085088.1 | IS110-like element ISSfl4 family transposase | - |
| F4V35_RS24545 | 54065..55756 | + | 1692 | WP_000597733.1 | T3SS effector E3 ubiquitin-protein ligase IpaH2.5 | - |
| F4V35_RS24550 | 55808..57016 | + | 1209 | Protein_75 | IS3 family transposase | - |
| F4V35_RS24555 | 57059..57582 | - | 524 | Protein_76 | IS3-like element ISSfl11 family transposase | - |
| F4V35_RS24560 | 57650..58132 | - | 483 | WP_000405245.1 | GNAT family N-acetyltransferase | Toxin Detail |
| F4V35_RS24565 | 58123..58425 | - | 303 | WP_010921625.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| F4V35_RS24575 | 58697..58969 | + | 273 | WP_000019158.1 | hypothetical protein | - |
| F4V35_RS24580 | 58950..60158 | + | 1209 | WP_000198552.1 | IS91 family transposase | - |
| F4V35_RS24585 | 60330..60458 | + | 129 | Protein_81 | IS5/IS1182 family transposase | - |
| F4V35_RS24595 | 60607..62061 | - | 1455 | WP_000701108.1 | type 3 secretion system effector OspC2 | - |
| F4V35_RS24600 | 62465..63084 | + | 620 | Protein_83 | IS1 family transposase | - |
| F4V35_RS24605 | 63134..63869 | + | 736 | Protein_84 | IS3 family transposase | - |
| F4V35_RS24615 | 64542..66050 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| F4V35_RS24620 | 66140..66613 | + | 474 | Protein_86 | IS3 family transposase | - |
| F4V35_RS24625 | 66657..67067 | + | 411 | Protein_87 | transposase | - |
| F4V35_RS24630 | 67099..67713 | + | 615 | Protein_88 | IS21-like element ISEc10 family helper ATPase IstB | - |
| F4V35_RS24635 | 67882..71976 | - | 4095 | WP_001034121.1 | serine protease autotransporter toxin SepA | - |
| F4V35_RS24645 | 72378..72566 | + | 189 | WP_000957853.1 | hypothetical protein | - |
| F4V35_RS24650 | 72576..73774 | + | 1199 | WP_094081567.1 | IS91 family transposase | - |
| F4V35_RS24655 | 73943..74449 | - | 507 | Protein_92 | IS3 family transposase | - |
| F4V35_RS24660 | 74512..74916 | - | 405 | WP_011114759.1 | hypothetical protein | - |
| F4V35_RS26055 | 75106..75234 | - | 129 | Protein_94 | IS630 family transposase | - |
| F4V35_RS25465 | 75468..76184 | - | 717 | WP_171768513.1 | hypothetical protein | - |
| F4V35_RS24670 | 76768..77168 | - | 401 | Protein_96 | transposase | - |
| F4V35_RS24675 | 77201..77655 | - | 455 | Protein_97 | transposase | - |
| F4V35_RS24680 | 77708..78918 | + | 1211 | Protein_98 | IS3 family transposase | - |
| F4V35_RS24690 | 78951..79100 | - | 150 | Protein_99 | transposase | - |
| F4V35_RS24695 | 79275..79704 | - | 430 | Protein_100 | transposase | - |
| F4V35_RS24700 | 79752..80117 | - | 366 | WP_000124083.1 | hypothetical protein | - |
| F4V35_RS25470 | 80870..81268 | - | 399 | Protein_102 | reverse transcriptase/maturase family protein | - |
| F4V35_RS24720 | 81271..81637 | - | 367 | Protein_103 | IS3 family transposase | - |
| F4V35_RS24725 | 81639..82326 | - | 688 | Protein_104 | IS3 family transposase | - |
| F4V35_RS24730 | 82505..83707 | - | 1203 | WP_001195004.1 | alpha-tubulin-specific protease | - |
| F4V35_RS24735 | 84236..87543 | + | 3308 | Protein_106 | outer membrane autotransporter IcsA | - |
| F4V35_RS24740 | 87687..88005 | + | 319 | Protein_107 | fimbria/pilus outer membrane usher protein | - |
| F4V35_RS24745 | 88178..89387 | + | 1210 | Protein_108 | IS3 family transposase | - |
| F4V35_RS24750 | 89728..91380 | + | 1653 | WP_000612525.1 | bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA | - |
| F4V35_RS24755 | 91391..91561 | - | 171 | Protein_110 | transposase | - |
| F4V35_RS26060 | 91694..91813 | - | 120 | Protein_111 | transposase domain-containing protein | - |
| F4V35_RS24765 | 91887..92886 | - | 1000 | Protein_112 | group II intron reverse transcriptase/maturase | - |
| F4V35_RS24770 | 93100..93300 | - | 201 | Protein_113 | IS3 family transposase | - |
| F4V35_RS24780 | 93678..94427 | + | 750 | WP_000828661.1 | phosphatase PAP2 family protein | - |
| F4V35_RS26065 | 94482..94586 | - | 105 | Protein_115 | hypothetical protein | - |
| F4V35_RS24790 | 95487..95867 | - | 381 | WP_005015412.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| F4V35_RS24795 | 96050..96445 | - | 396 | WP_000445929.1 | plasmid partitioning/stability family protein | - |
| F4V35_RS24800 | 96445..97404 | - | 960 | WP_000921952.1 | plasmid segregation protein ParM | - |
| F4V35_RS24810 | 97844..98746 | + | 903 | WP_015683198.1 | DUF1281 domain-containing protein | - |
| F4V35_RS24815 | 98743..99054 | + | 312 | WP_011114770.1 | hypothetical protein | - |
| F4V35_RS24820 | 99118..99801 | + | 684 | WP_000086135.1 | DNA methylase | - |
| F4V35_RS24825 | 99802..100023 | + | 222 | WP_001104887.1 | hypothetical protein | - |
| F4V35_RS24830 | 99983..100469 | + | 487 | Protein_124 | DUF1380 domain-containing protein | - |
| F4V35_RS24835 | 100514..101284 | + | 771 | WP_001006196.1 | hypothetical protein | - |
| F4V35_RS24845 | 101623..102342 | - | 720 | Protein_126 | IS110 family transposase | - |
| F4V35_RS24850 | 102351..103412 | - | 1062 | Protein_127 | IS66 family transposase | - |
| F4V35_RS24860 | 104668..105219 | - | 552 | Protein_129 | IS66 family transposase zinc-finger binding domain-containing protein | - |
| F4V35_RS24865 | 105216..105566 | - | 351 | WP_005048975.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| F4V35_RS24870 | 105563..106237 | - | 675 | WP_001088287.1 | IS66-like element accessory protein TnpA | - |
| F4V35_RS24880 | 106436..106906 | + | 471 | Protein_132 | IS1 family transposase | - |
| F4V35_RS25475 | 107065..107703 | + | 639 | WP_000607008.1 | type III secretion system effector OspI | - |
| F4V35_RS24890 | 107818..108087 | + | 270 | Protein_134 | transposase | - |
| F4V35_RS24895 | 108175..109217 | + | 1043 | Protein_135 | IS3 family transposase | - |
| F4V35_RS24900 | 109297..109971 | + | 675 | WP_004967157.1 | IS66-like element accessory protein TnpA | - |
| F4V35_RS24905 | 109968..110315 | + | 348 | WP_000631709.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| F4V35_RS24910 | 110335..111936 | + | 1602 | WP_011110603.1 | IS66-like element ISSfl3 family transposase | - |
| F4V35_RS24915 | 112125..112310 | + | 186 | Protein_139 | ATP-binding protein | - |
| F4V35_RS24920 | 112410..112619 | - | 210 | Protein_140 | peptidoglycan-binding protein | - |
| F4V35_RS24925 | 112669..112920 | - | 252 | WP_015683204.1 | transporter | - |
| F4V35_RS24935 | 113372..113656 | + | 285 | WP_011114774.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| F4V35_RS24940 | 113656..113931 | + | 276 | WP_000421262.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| F4V35_RS24955 | 114910..115863 | + | 954 | Protein_145 | IS66 family transposase | - |
| F4V35_RS24960 | 116399..116617 | + | 219 | WP_000813626.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| F4V35_RS24965 | 116619..116924 | + | 306 | WP_001159860.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| F4V35_RS24975 | 117317..118954 | + | 1638 | WP_000936806.1 | T3SS effector E3 ubiquitin-protein ligase IpaH9.8 | - |
| F4V35_RS24980 | 119162..119431 | + | 270 | Protein_149 | type II toxin-antitoxin system antitoxin YacA | - |
| F4V35_RS26070 | 119431..119600 | + | 170 | Protein_150 | type II toxin-antitoxin system toxin YacB | - |
| F4V35_RS24990 | 119683..120273 | + | 591 | WP_000705601.1 | type III secretion system effector protein kinase OspG | - |
| F4V35_RS24995 | 120630..120896 | + | 267 | Protein_152 | IS66 family insertion sequence element accessory protein TnpB | - |
| F4V35_RS25000 | 120959..122227 | + | 1269 | Protein_153 | IS4 family transposase | - |
| F4V35_RS25005 | 122284..123493 | + | 1210 | Protein_154 | IS3 family transposase | - |
| F4V35_RS26075 | 123534..123614 | + | 81 | Protein_155 | hypothetical protein | - |
| F4V35_RS25010 | 123628..123819 | - | 192 | Protein_156 | IS66 family insertion sequence element accessory protein TnpB | - |
| F4V35_RS25015 | 123817..124141 | + | 325 | Protein_157 | IS3 family transposase | - |
| F4V35_RS25020 | 124171..127082 | - | 2912 | Protein_158 | hypothetical protein | - |
| F4V35_RS25030 | 127565..128407 | + | 843 | WP_000931197.1 | polysaccharide deacetylase family protein | - |
| F4V35_RS25035 | 128410..129498 | + | 1089 | WP_010921719.1 | putative hexosyltransferase CapU | - |
| F4V35_RS25040 | 129503..130453 | + | 951 | WP_015683210.1 | virulence factor VirK | - |
| F4V35_RS25045 | 130518..131462 | + | 945 | WP_004996485.1 | lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase | - |
| F4V35_RS25050 | 131616..132539 | - | 924 | Protein_163 | IS630 family transposase | - |
| F4V35_RS25060 | 133785..133964 | + | 180 | Protein_165 | hypothetical protein | - |
| F4V35_RS25065 | 133973..134371 | - | 399 | WP_000911311.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| F4V35_RS25070 | 134371..134598 | - | 228 | WP_000450531.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| F4V35_RS25080 | 134680..139932 | + | 5253 | Protein_168 | conjugative transfer relaxase/helicase TraI | - |
| F4V35_RS25085 | 139952..140698 | + | 747 | WP_000205722.1 | conjugal transfer pilus acetylase TraX | - |
| F4V35_RS25090 | 140753..141313 | + | 561 | WP_000139368.1 | fertility inhibition protein FinO | - |
| F4V35_RS25095 | 141444..141656 | + | 213 | WP_004971339.1 | ANR family transcriptional regulator | - |
| F4V35_RS25105 | 141900..142139 | + | 240 | Protein_172 | thermonuclease family protein | - |
| F4V35_RS25120 | 143365..143628 | + | 264 | Protein_174 | thermonuclease family protein | - |
| F4V35_RS25125 | 143674..143883 | + | 210 | WP_001299729.1 | hemolysin expression modulator Hha | - |
| F4V35_RS25130 | 143922..144512 | + | 591 | WP_000766818.1 | DUF2726 domain-containing protein | - |
| F4V35_RS25135 | 144752..145012 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| F4V35_RS25145 | 145236..145310 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| F4V35_RS25150 | 145303..146160 | + | 858 | WP_000130973.1 | incFII family plasmid replication initiator RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|