MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 99461 bp
Accession: NZ_CP043230 Location: 1..99461 Organism: Escherichia coli strain Ec-050 Replicon: plasmid pEc-050-NDM-5
Accession: NZ_CP043230 Location: 1..99461 Organism: Escherichia coli strain Ec-050 Replicon: plasmid pEc-050-NDM-5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FX998_RS24690 () | 127..1175 | - | 1049 | Protein_1 | IS3 family transposase ISKpn11 | Transposase |
| FX998_RS24695 () | 1267..1809 | - | 543 | WP_002063889.1 | AAA family ATPase | - |
| FX998_RS24700 () | 1822..2682 | - | 861 | WP_000557452.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| FX998_RS24705 () | 2789..3493 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FX998_RS24710 () | 3541..4230 | + | 690 | Protein_5 | IS6 family transposase IS6100 | Transposase |
| FX998_RS24725 () | 4723..5307 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| FX998_RS24730 () | 5307..6545 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| FX998_RS24735 () | 6542..7447 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| FX998_RS24745 () | 7569..8273 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FX998_RS24750 () | 8298..8672 | + | 375 | WP_024193849.1 | IS66 family transposase ISKpn24 | Transposase |
| FX998_RS24755 () | 8721..9666 | + | 946 | Protein_11 | IS66 family transposase ISEc8 | Transposase |
| FX998_RS24760 () | 9752..10774 | + | 1023 | WP_000255956.1 | IS21 family transposase IS100kyp | Transposase |
| FX998_RS24765 () | 10774..11553 | + | 780 | WP_001297096.1 | IS21 family transposase IS100kyp | Transposase |
| FX998_RS24770 () | 11621..12229 | + | 609 | Protein_14 | IS66 family transposase ISEc22 | Transposase |
| FX998_RS24775 () | 12292..13083 | - | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| FX998_RS24780 () | 13090..15060 | - | 1971 | WP_001496335.1 | Hemin receptor | VF |
| FX998_RS24785 () | 15342..15778 | + | 437 | Protein_17 | IS3 family transposase IS2 | Transposase |
| FX998_RS24790 () | 16303..16575 | + | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| FX998_RS24795 () | 17021..17196 | + | 176 | Protein_19 | IS3 family transposase | - |
| FX998_RS24800 () | 17422..18591 | - | 1170 | WP_001072358.1 | hypothetical protein | - |
| FX998_RS24805 () | 18958..19146 | + | 189 | WP_001309252.1 | hypothetical protein | - |
| FX998_RS24810 () | 19267..20007 | + | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| FX998_RS24815 () | 20292..21269 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| FX998_RS24825 () | 22015..22338 | + | 324 | Protein_24 | IS21 family transposase IS21 | Transposase |
| FX998_RS24830 () | 22340..22444 | + | 105 | Protein_25 | AAA family ATPase | - |
| FX998_RS24835 () | 22505..23018 | + | 514 | Protein_26 | DUF4113 domain-containing protein | - |
| FX998_RS24840 () | 23198..23895 | - | 698 | Protein_27 | IS1 family transposase IS1R | Transposase |
| FX998_RS24850 () | 24251..25165 | + | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| FX998_RS24855 () | 25165..25992 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| FX998_RS24860 () | 25989..26846 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| FX998_RS24865 () | 26843..27700 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| FX998_RS24870 () | 27934..28191 | - | 258 | Protein_32 | Tn3 family transposase | - |
| FX998_RS24875 () | 28189..28602 | + | 414 | Protein_33 | phosphopyruvate hydratase | - |
| FX998_RS24885 () | 28943..29323 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| FX998_RS24890 () | 29703..30896 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| FX998_RS24895 () | 31032..32756 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| FX998_RS24900 () | 32757..33704 | + | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| FX998_RS24905 () | 33704..35446 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| FX998_RS24910 () | 35443..36720 | + | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| FX998_RS24915 () | 36802..39003 | + | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| FX998_RS24920 () | 39529..40215 | + | 687 | Protein_41 | IS1 family transposase IS1S | Transposase |
| FX998_RS24925 () | 40469..41491 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| FX998_RS24930 () | 41476..43041 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| FX998_RS24935 () | 43116..43532 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FX998_RS24940 () | 43529..43759 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| FX998_RS24950 () | 44319..44537 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| FX998_RS24955 () | 44539..44844 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| FX998_RS24960 () | 44845..45651 | + | 807 | WP_000016970.1 | site-specific integrase | - |
| FX998_RS24965 () | 46373..47128 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| FX998_RS24970 () | 47716..48882 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| FX998_RS24975 () | 48882..49853 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FX998_RS24985 () | 50591..51493 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| FX998_RS24990 () | 51497..51801 | + | 305 | Protein_53 | hypothetical protein | - |
| FX998_RS24995 () | 51878..52561 | + | 684 | WP_032181561.1 | DNA methylase | - |
| FX998_RS25000 () | 52562..52783 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| FX998_RS25005 () | 52797..53231 | + | 435 | WP_001546462.1 | DUF1380 family protein | - |
| FX998_RS25010 () | 53276..54046 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| FX998_RS25015 () | 54046..54487 | + | 442 | Protein_58 | DUF1472 domain-containing protein | - |
| FX998_RS25020 () | 54583..54885 | + | 303 | WP_001666994.1 | antirestriction protein | - |
| FX998_RS25025 () | 54932..55354 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| FX998_RS25550 () | 55351..55521 | + | 171 | WP_086625069.1 | hypothetical protein | - |
| FX998_RS25030 () | 55460..56236 | + | 777 | WP_086625070.1 | conjugal transfer pilus acetylase TraX | - |
| FX998_RS25035 () | 56291..56851 | + | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| FX998_RS25040 () | 56985..57197 | + | 213 | WP_005012601.1 | hypothetical protein | - |
| FX998_RS25555 () | 57498..57587 | - | 90 | Protein_65 | IS1 family transposase | - |
| FX998_RS25055 () | 57642..58319 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| FX998_RS25060 () | 58319..58666 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| FX998_RS25065 () | 58686..60257 | + | 1572 | WP_023149734.1 | IS66 family transposase ISCro1 | Transposase |
| FX998_RS25070 () | 60295..60911 | - | 617 | Protein_69 | IS1 family transposase | - |
| FX998_RS25075 () | 61012..61194 | + | 183 | WP_000968309.1 | hypothetical protein | - |
| - () | 61333..61394 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 61333..61394 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 61333..61394 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - () | 61333..61394 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| FX998_RS25085 () | 61381..61587 | + | 207 | WP_015387399.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FX998_RS25090 () | 61871..62128 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| FX998_RS25100 () | 62364..62438 | + | 75 | WP_032336874.1 | RepA leader peptide Tap | - |
| FX998_RS25105 () | 62431..62877 | + | 447 | Protein_74 | incFII family plasmid replication initiator RepA | - |
| FX998_RS25110 () | 62823..63305 | - | 483 | Protein_75 | VENN motif pre-toxin domain-containing protein | - |
| FX998_RS25115 () | 64198..65418 | + | 1221 | WP_000410951.1 | arginine deiminase | - |
| FX998_RS25120 () | 65429..66340 | + | 912 | WP_000440183.1 | carbamate kinase | - |
| FX998_RS25125 () | 66425..67429 | + | 1005 | WP_086625071.1 | Ornithine carbamoyltransferase | VF |
| FX998_RS25130 () | 67477..68880 | + | 1404 | WP_000514417.1 | YfcC family protein | - |
| FX998_RS25135 () | 68961..69440 | + | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| FX998_RS25140 () | 69504..69845 | - | 342 | Protein_81 | IS66 family transposase IS682 | Transposase |
| FX998_RS25145 () | 69797..70018 | - | 222 | WP_000080227.1 | IS66 family transposase ISEc43 | Transposase |
| FX998_RS25150 () | 70049..70399 | - | 351 | WP_000624725.1 | IS66 family transposase ISEc47 | Transposase |
| FX998_RS25155 () | 70396..70758 | - | 363 | WP_059330006.1 | IS66 family transposase ISEc23 | Transposase |
| FX998_RS25160 () | 70867..71564 | - | 698 | Protein_85 | IS1 family transposase IS1A | Transposase |
| FX998_RS25165 () | 71597..72175 | + | 579 | WP_032152936.1 | DUF2726 domain-containing protein | - |
| FX998_RS25170 () | 72588..72941 | - | 354 | WP_000005489.1 | hypothetical protein | - |
| FX998_RS25175 () | 73413..74435 | - | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| FX998_RS25185 () | 74840..75097 | + | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| FX998_RS25195 () | 75332..75406 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| FX998_RS25200 () | 75399..76256 | + | 858 | WP_032152935.1 | incFII family plasmid replication initiator RepA | - |
| FX998_RS25560 () | 76957..77097 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| FX998_RS25210 () | 77195..77389 | + | 195 | WP_148905645.1 | histidine phosphatase family protein | - |
| FX998_RS25215 () | 77515..77847 | + | 333 | WP_072134990.1 | CPBP family intramembrane metalloprotease | - |
| FX998_RS25220 () | 77940..78197 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FX998_RS25225 () | 78130..78530 | + | 401 | Protein_96 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FX998_RS25230 () | 78667..81564 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| FX998_RS25235 () | 81659..82264 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| FX998_RS25240 () | 82288..83037 | - | 750 | Protein_99 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FX998_RS25245 () | 83026..83433 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| FX998_RS25250 () | 83571..84455 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| FX998_RS25255 () | 84487..85686 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| FX998_RS25260 () | 85792..86442 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| FX998_RS25265 () | 86474..86716 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| FX998_RS25270 () | 86758..88272 | - | 1515 | Protein_105 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| FX998_RS25275 () | 88338..89042 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FX998_RS25280 () | 89097..89963 | - | 867 | Protein_107 | IS91 family transposase ISAzo26 | Transposase |
| FX998_RS25285 () | 90108..90605 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| FX998_RS25290 () | 90717..91007 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| FX998_RS25295 () | 91013..91804 | + | 792 | WP_001206356.1 | Streptomycin 3''-adenylyltransferase | ARG |
| FX998_RS25300 () | 91968..92315 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| FX998_RS25305 () | 92309..93148 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| FX998_RS25310 () | 93553..95094 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| FX998_RS25320 () | 95407..96438 | + | 1032 | WP_004201169.1 | protein-disulfide reductase DsbD N-terminal domain-containing protein | - |
| FX998_RS25325 () | 96449..97087 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| FX998_RS25330 () | 97092..97457 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| FX998_RS25335 () | 97461..98273 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| FX998_RS25340 () | 98374..98667 | - | 294 | Protein_118 | IS30 family transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|