MGE detailed information
MGE type: Conjugative plasmid MGE length: 143714 bp
Accession: NZ_CP040922 Location: 1..143714 Organism: Escherichia coli strain FC853_EC Replicon: plasmid p853EC3
Accession: NZ_CP040922 Location: 1..143714 Organism: Escherichia coli strain FC853_EC Replicon: plasmid p853EC3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FH485_RS26530 () | 8..430 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| FH485_RS26535 () | 427..618 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| FH485_RS26540 () | 588..1138 | - | 551 | Protein_2 | hypothetical protein | - |
| FH485_RS26550 () | 1650..1880 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| FH485_RS26555 () | 1932..3293 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| FH485_RS26560 () | 3341..3904 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| FH485_RS26565 () | 3930..4136 | + | 207 | WP_001774176.1 | hypothetical protein | - |
| FH485_RS26595 () | 4778..5317 | + | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| FH485_RS26600 () | 5380..5613 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| FH485_RS26605 () | 5679..7637 | + | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| FH485_RS26610 () | 7692..8126 | + | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| FH485_RS26615 () | 8123..8842 | + | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| - () | 8854..8956 | + | 103 | NuclAT_1 | - | - |
| - () | 8854..8956 | + | 103 | NuclAT_1 | - | - |
| - () | 8854..8956 | + | 103 | NuclAT_1 | - | - |
| - () | 8854..8956 | + | 103 | NuclAT_1 | - | - |
| FH485_RS26620 () | 9002..10371 | + | 1370 | WP_140028060.1 | IS3 family transposase IS150 | Transposase |
| - () | 10398..10525 | + | 128 | NuclAT_0 | - | - |
| - () | 10398..10525 | + | 128 | NuclAT_0 | - | - |
| - () | 10398..10525 | + | 128 | NuclAT_0 | - | - |
| - () | 10398..10525 | + | 128 | NuclAT_0 | - | - |
| FH485_RS26630 () | 10569..10727 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FH485_RS26650 () | 11504..11623 | + | 120 | WP_032165723.1 | hypothetical protein | - |
| FH485_RS26655 () | 11648..11935 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| FH485_RS26660 () | 12054..12875 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| FH485_RS26665 () | 13172..13774 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| FH485_RS26670 () | 14105..14488 | + | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| FH485_RS26675 () | 14622..15299 | + | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| FH485_RS26680 () | 15387..15614 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| FH485_RS26685 () | 15648..16010 | + | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| FH485_RS26690 () | 16015..16095 | + | 81 | Protein_22 | type IV conjugative transfer system protein TraL | - |
| FH485_RS26695 () | 16155..16852 | + | 698 | Protein_23 | IS1 family transposase IS1G | Transposase |
| FH485_RS26700 () | 16969..17253 | + | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| FH485_RS26705 () | 17240..17785 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| FH485_RS26710 () | 17715..18062 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| FH485_RS26715 () | 18010..18435 | + | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| FH485_RS26720 () | 18422..19795 | + | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| FH485_RS26725 () | 19792..22611 | + | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| FH485_RS26730 () | 22630..23127 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| FH485_RS26735 () | 23159..23890 | + | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| FH485_RS26740 () | 24093..24872 | + | 780 | WP_000199914.1 | hypothetical protein | - |
| FH485_RS26745 () | 24869..27094 | + | 2226 | WP_047605472.1 | type IV conjugative transfer system coupling protein TraD | - |
| FH485_RS26750 () | 27094..32364 | + | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| FH485_RS26755 () | 32384..33130 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| FH485_RS26760 () | 33185..33745 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| FH485_RS26765 () | 33876..34088 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| FH485_RS26775 () | 34601..34887 | + | 287 | Protein_38 | DUF2726 domain-containing protein | - |
| - () | 34854..34914 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 34854..34914 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 34854..34914 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 34854..34914 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| FH485_RS26780 () | 34959..35093 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| FH485_RS26785 () | 35390..35500 | + | 111 | Protein_40 | replication protein | - |
| FH485_RS26790 () | 35569..36348 | - | 780 | WP_001323403.1 | IS21 family transposase IS100kyp | Transposase |
| FH485_RS26795 () | 36348..37370 | - | 1023 | WP_000255944.1 | IS21 family transposase IS100kyp | Transposase |
| FH485_RS26800 () | 37451..37603 | + | 153 | WP_072258247.1 | replication protein A | - |
| FH485_RS26805 () | 37840..37914 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| FH485_RS26810 () | 37907..38764 | + | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| FH485_RS28025 () | 39466..39606 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| FH485_RS26820 () | 39704..40357 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| FH485_RS26825 () | 40450..40707 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| FH485_RS26830 () | 40640..41041 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| FH485_RS26835 () | 41326..42636 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| FH485_RS26840 () | 42665..42763 | + | 99 | Protein_51 | IS1 family transposase | - |
| FH485_RS26845 () | 42913..43773 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| FH485_RS26850 () | 44015..44719 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FH485_RS26855 () | 44771..45397 | + | 627 | Protein_54 | IS6 family transposase IS6100 | Transposase |
| FH485_RS26865 () | 45599..46435 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| FH485_RS26870 () | 46435..47112 | - | 678 | WP_180375365.1 | signal peptidase II | - |
| FH485_RS26875 () | 47057..50059 | - | 3003 | WP_024946709.1 | Tn3 family transposase TnpA_ISXc4 | Transposase |
| FH485_RS26880 () | 50202..51701 | + | 1500 | WP_024946710.1 | IS21 family transposase ISMdi27 | Transposase |
| FH485_RS26885 () | 51701..52435 | + | 735 | WP_033878928.1 | IS21 family transposase ISPkr1 | Transposase |
| FH485_RS26890 () | 52633..53265 | + | 633 | WP_024946712.1 | OsmC family protein | - |
| FH485_RS26895 () | 53474..54232 | - | 759 | WP_024946713.1 | IS21 family transposase ISPve1 | Transposase |
| FH485_RS26900 () | 54229..54942 | - | 714 | Protein_62 | IS21 family transposase ISPve1 | Transposase |
| FH485_RS26905 () | 54976..57860 | - | 2885 | Protein_63 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| FH485_RS26910 () | 57986..58654 | + | 669 | WP_023434504.1 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| FH485_RS26915 () | 58666..59469 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| FH485_RS26920 () | 59469..60305 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| FH485_RS26930 () | 60412..60642 | + | 231 | Protein_67 | IS6 family transposase | - |
| FH485_RS26945 () | 61135..61719 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| FH485_RS26950 () | 61719..62956 | - | 1238 | Protein_69 | MFS transporter | - |
| FH485_RS26955 () | 62953..63867 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| FH485_RS26965 () | 63989..64681 | - | 693 | Protein_71 | IS6 family transposase | - |
| FH485_RS26970 () | 64816..64911 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| FH485_RS26975 () | 65037..65774 | + | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| FH485_RS28030 () | 65719..65889 | + | 171 | WP_170852050.1 | rRNA adenine methyltransferase | - |
| FH485_RS26985 () | 66404..66853 | + | 450 | WP_073518795.1 | hypothetical protein | - |
| FH485_RS28035 () | 66814..67155 | + | 342 | WP_023909256.1 | 60 kDa chaperonin 2 | VF |
| FH485_RS26995 () | 67429..68905 | + | 1477 | Protein_77 | IS91 family transposase ISVsa3 | Transposase |
| FH485_RS27005 () | 69228..69854 | - | 627 | Protein_78 | IS6 family transposase IS26 | Transposase |
| FH485_RS27010 () | 69910..70584 | + | 675 | Protein_79 | IS1 family transposase IS1R | Transposase |
| FH485_RS27015 () | 70581..70844 | + | 264 | WP_049802299.1 | antibiotic biosynthesis monooxygenase | - |
| FH485_RS27020 () | 70837..71223 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| FH485_RS27025 () | 71231..71917 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| FH485_RS27030 () | 71895..72518 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| FH485_RS27035 () | 72600..73805 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| FH485_RS27040 () | 73918..74511 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| FH485_RS27045 () | 74670..75365 | - | 696 | Protein_86 | IS1 family transposase | - |
| FH485_RS27060 () | 75828..75986 | + | 159 | WP_000449408.1 | DsbA family protein | - |
| FH485_RS27065 () | 75976..76482 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| FH485_RS27070 () | 76665..77480 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| FH485_RS27080 () | 77827..79713 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| FH485_RS27085 () | 79754..80281 | + | 528 | WP_000178050.1 | iron transporter | - |
| FH485_RS27090 () | 80385..81764 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| FH485_RS27095 () | 81767..83050 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| FH485_RS27100 () | 83040..84170 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| FH485_RS27105 () | 84175..84870 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| FH485_RS27110 () | 84857..85342 | + | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| FH485_RS27115 () | 85367..85852 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| FH485_RS27120 () | 85974..86504 | + | 531 | Protein_98 | histidine-type phosphatase | - |
| FH485_RS27125 () | 86562..87266 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| FH485_RS27130 () | 87291..88487 | + | 1197 | Protein_100 | IS3 family transposase | - |
| FH485_RS27135 () | 88509..88742 | + | 234 | Protein_101 | Tn3 family transposase ISPsy39 | Transposase |
| FH485_RS27140 () | 88819..89127 | + | 309 | Protein_102 | IS4 family transposase ISEc13 | Transposase |
| FH485_RS27145 () | 89186..90496 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| FH485_RS27150 () | 90489..91562 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| FH485_RS27155 () | 91568..92392 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| FH485_RS27160 () | 92403..93290 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| FH485_RS27165 () | 93280..94158 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| FH485_RS27170 () | 94289..94729 | - | 441 | Protein_108 | zinc-binding dehydrogenase | - |
| FH485_RS27175 () | 94703..94897 | + | 195 | WP_000796505.1 | hypothetical protein | - |
| FH485_RS27180 () | 95130..96019 | + | 890 | Protein_110 | dihydrodipicolinate synthase family protein | - |
| FH485_RS27185 () | 96044..96424 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| FH485_RS27190 () | 96457..97422 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| FH485_RS27195 () | 97468..98220 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| FH485_RS27200 () | 98825..99109 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| FH485_RS27205 () | 99109..99384 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| FH485_RS27210 () | 99490..99783 | + | 294 | WP_001105060.1 | hypothetical protein | - |
| FH485_RS27215 () | 99818..99946 | - | 129 | Protein_117 | IS481 family transposase | - |
| FH485_RS27220 () | 99979..101148 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| FH485_RS27230 () | 101641..101948 | + | 308 | Protein_119 | type II toxin-antitoxin system ParD family antitoxin | - |
| FH485_RS27240 () | 102291..102473 | + | 183 | WP_042344623.1 | hypothetical protein | - |
| FH485_RS27245 () | 102594..103334 | + | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| FH485_RS27250 () | 103619..104596 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| FH485_RS27260 () | 105342..105665 | + | 324 | Protein_123 | IS21 family transposase IS21 | Transposase |
| FH485_RS27265 () | 105667..105771 | + | 105 | Protein_124 | AAA family ATPase | - |
| FH485_RS27270 () | 105832..106345 | + | 514 | Protein_125 | DUF4113 domain-containing protein | - |
| FH485_RS27275 () | 106524..107220 | - | 697 | Protein_126 | IS1 family transposase IS1S | Transposase |
| FH485_RS27280 () | 107600..109801 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| FH485_RS27285 () | 109883..111160 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| FH485_RS27290 () | 111157..112899 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| FH485_RS27295 () | 112899..113846 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| FH485_RS27300 () | 113847..115571 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| FH485_RS27305 () | 115707..116900 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| FH485_RS27310 () | 117280..117660 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| FH485_RS27320 () | 118001..118414 | - | 414 | Protein_134 | phosphopyruvate hydratase | - |
| FH485_RS27325 () | 118412..118669 | + | 258 | Protein_135 | Tn3 family transposase | - |
| FH485_RS27330 () | 118903..119760 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| FH485_RS27335 () | 119757..120614 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| FH485_RS27340 () | 120611..121438 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| FH485_RS27345 () | 121438..122352 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| FH485_RS27355 () | 122708..123405 | + | 698 | Protein_140 | IS1 family transposase IS1S | Transposase |
| FH485_RS27360 () | 123659..124681 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| FH485_RS27365 () | 124666..126230 | - | 1565 | Protein_142 | AAA family ATPase | - |
| FH485_RS27370 () | 126305..126721 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | - |
| FH485_RS27375 () | 126718..126947 | - | 230 | Protein_144 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| FH485_RS27380 () | 127328..131121 | + | 3794 | Protein_145 | pcar | - |
| FH485_RS27385 () | 131166..131582 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| FH485_RS27390 () | 131579..131809 | - | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| FH485_RS27395 () | 132074..132574 | + | 501 | WP_000528931.1 | hypothetical protein | - |
| FH485_RS27400 () | 132587..133360 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| FH485_RS27405 () | 133527..134660 | + | 1134 | WP_001542067.1 | DUF3800 domain-containing protein | - |
| FH485_RS27410 () | 134694..135206 | - | 513 | WP_000151784.1 | hypothetical protein | - |
| FH485_RS27415 () | 135773..135991 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| FH485_RS27420 () | 135993..136298 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| FH485_RS27425 () | 136299..137105 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| FH485_RS27430 () | 137879..138634 | + | 756 | WP_024946706.1 | replication initiation protein RepE | - |
| FH485_RS27435 () | 139222..140388 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| FH485_RS27440 () | 140388..141359 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| FH485_RS27455 () | 142227..143129 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| FH485_RS27460 () | 143133..143437 | + | 305 | Protein_159 | hypothetical protein | - |
| FH485_RS27465 () | 143514..143714 | + | 201 | Protein_160 | DNA methylase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|