NZ_CP0358181..162860

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 162860 bp
Accession: NZ_CP035818        Location: 1..162860         Organism: Escherichia coli strain E7476       Replicon: plasmid pE7476_162


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EXA08_RS24450 (496) 496..807 + 312 WP_000729511.1 hypothetical protein -
EXA08_RS24455 (1272) 1272..1520 + 249 WP_000513531.1 type II toxin-antitoxin system HicA family toxin Toxin Detail
EXA08_RS24460 (1517) 1517..1864 + 348 WP_000681610.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin Detail
EXA08_RS24465 (2091) 2091..3262 - 1172 Protein_4 IS91 family transposase ISEc37 Transposase
EXA08_RS24470 (3262) 3262..3627 - 366 WP_000124139.1 hypothetical protein -
EXA08_RS24475 (3709) 3709..4311 + 603 Protein_6 IS3 family transposase IS2 Transposase
EXA08_RS24480 (4513) 4513..6324 + 1812 WP_000260520.1 Heme/hemopexin transporter protein HuxB VF
EXA08_RS24485 (6415) 6415..10956 + 4542 WP_100004201.1 Heme/hemopexin-binding protein VF
EXA08_RS24490 (10981) 10981..11166 + 186 WP_000894829.1 hypothetical protein -
EXA08_RS24495 (11241) 11241..13154 + 1914 WP_000986904.1 UDP-glucose:protein N-beta-glucosyltransferase VF
EXA08_RS24500 (13151) 13151..13645 + 495 WP_001203078.1 DUF2919 family protein -
EXA08_RS24505 (13717) 13717..13986 - 270 Protein_12 IS21 family transposase -
EXA08_RS24510 (14166) 14166..14807 + 642 WP_000470628.1 Tn3 family transposase TnpR_TnEc1 Transposase
EXA08_RS24515 (14856) 14856..15740 + 885 Protein_14 IS66 family transposase ISEc43 Transposase
EXA08_RS24520 (16006) 16006..16212 - 207 Protein_15 IS5 family transposase IS903B Transposase
EXA08_RS24525 (16442) 16442..17806 + 1365 Protein_16 IS21 family transposase ISEc12 Transposase
EXA08_RS24530 (17863) 17863..19076 + 1214 WP_187536093.1 IS3 family transposase IS629 Transposase
EXA08_RS24535 (19115) 19115..19297 + 183 Protein_18 IS21 family transposase -
EXA08_RS24540 (19312) 19312..20058 + 747 WP_001016257.1 IS21 family transposase ISEc12 Transposase
EXA08_RS24545 (20264) 20264..20482 - 219 WP_013188501.1 Heat-stable enterotoxin A3/A4 VF
EXA08_RS24550 (20859) 20859..21392 + 534 Protein_21 IS3 family transposase ISKpn38 Transposase
EXA08_RS24555 (21456) 21456..22504 + 1049 Protein_22 IS3 family transposase ISEc16 Transposase
EXA08_RS24560 (22989) 22989..24119 + 1131 WP_000258161.1 ABC transporter permease -
EXA08_RS24565 (24116) 24116..25342 + 1227 WP_001269347.1 TolC family protein -
EXA08_RS24570 (25239) 25239..26060 + 822 WP_032181798.1 membrane protein -
EXA08_RS24575 (26053) 26053..26682 + 630 WP_000593532.1 ABC transporter ATP-binding protein -
EXA08_RS24580 (26694) 26694..27908 + 1215 WP_001498835.1 hypothetical protein -
EXA08_RS24585 (28001) 28001..28531 + 531 Protein_28 Tn3 family transposase -
EXA08_RS24590 (28678) 28678..28897 + 220 Protein_29 IS3 family transposase -
EXA08_RS24595 (28960) 28960..29266 + 307 Protein_30 transposase -
EXA08_RS24600 (29465) 29465..29818 - 354 WP_001494857.1 hypothetical protein -
EXA08_RS24605 (30302) 30302..30547 + 246 Protein_32 IS3 family transposase ISEhe3 Transposase
EXA08_RS24615 (31873) 31873..32055 - 183 WP_001464039.1 IS66 family transposase ISEc23 Transposase
EXA08_RS24620 (32086) 32086..32436 - 351 WP_000624722.1 IS66 family transposase ISEc23 Transposase
EXA08_RS24625 (32433) 32433..32777 - 345 WP_000148487.1 IS66 family transposase ISEc23 Transposase
EXA08_RS24630 (32769) 32769..33749 + 981 WP_000019402.1 IS5 family transposase IS5D Transposase
EXA08_RS24635 (34107) 34107..34337 + 231 WP_000217718.1 hypothetical protein -
EXA08_RS24640 (34389) 34389..35750 + 1362 WP_000170658.1 DUF3560 domain-containing protein -
EXA08_RS24645 (35797) 35797..36360 + 564 WP_001460283.1 class I SAM-dependent methyltransferase -
EXA08_RS25595 (36446) 36446..36896 - 451 Protein_41 hypothetical protein -
EXA08_RS24650 (37198) 37198..37725 + 528 WP_000290822.1 single-stranded DNA-binding protein -
EXA08_RS24655 (37782) 37782..38015 + 234 WP_000005971.1 DUF905 domain-containing protein -
EXA08_RS24660 (38079) 38079..40043 + 1965 WP_001759171.1 ParB/RepB/Spo0J family partition protein -
EXA08_RS24665 (40098) 40098..40532 + 435 WP_000845950.1 conjugation system SOS inhibitor PsiB -
EXA08_RS24670 (40529) 40529..41248 + 720 WP_000994093.1 plasmid SOS inhibition protein A -
EXA08_RS24675 (41245) 41245..41559 + 315 WP_000872086.1 hypothetical protein -
- (41516) 41516..41716 + 201 NuclAT_0 - -
- (41516) 41516..41716 + 201 NuclAT_0 - -
- (41516) 41516..41716 + 201 NuclAT_0 - -
- (41516) 41516..41716 + 201 NuclAT_0 - -
EXA08_RS25600 (41710) 41710..41862 + 153 Protein_48 FlmC family protein -
EXA08_RS24680 (41807) 41807..41929 + 123 WP_223195199.1 Hok/Gef family protein -
EXA08_RS25605 (42230) 42230..42340 - 111 Protein_50 hypothetical protein -
EXA08_RS24690 (42426) 42426..43076 + 651 WP_000993921.1 IS66 family transposase IS679 Transposase
EXA08_RS24695 (43076) 43076..43423 + 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
EXA08_RS24700 (43443) 43443..45014 + 1572 WP_021554597.1 IS66 family transposase ISCro1 Transposase
EXA08_RS25610 (45069) 45069..45239 - 171 Protein_54 hypothetical protein -
EXA08_RS24705 (45536) 45536..45832 + 297 WP_001272251.1 hypothetical protein -
EXA08_RS24710 (45944) 45944..46765 + 822 WP_001234441.1 DUF932 domain-containing protein -
EXA08_RS24715 (47062) 47062..47568 - 507 WP_000843913.1 hypothetical protein VF
EXA08_RS24720 (48038) 48038..48421 + 384 WP_001137411.1 conjugal transfer relaxosome DNA-binding protein TraM -
EXA08_RS24725 (49821) 49821..50180 + 360 WP_001054220.1 type IV conjugative transfer system pilin TraA -
EXA08_RS24730 (50182) 50182..50487 + 306 WP_000016323.1 type IV conjugative transfer system protein TraL -
EXA08_RS24735 (50507) 50507..51070 + 564 WP_000406020.1 type IV conjugative transfer system protein TraE -
EXA08_RS24740 (51117) 51117..51800 + 684 WP_225877614.1 type-F conjugative transfer system secretin TraK -
EXA08_RS24745 (51787) 51787..53151 + 1365 WP_000024505.1 F-type conjugal transfer pilus assembly protein TraB -
EXA08_RS24750 (53263) 53263..53487 + 225 WP_000786056.1 TraR/DksA C4-type zinc finger protein -
EXA08_RS24755 (53491) 53491..53676 + 186 WP_000797318.1 hypothetical protein -
EXA08_RS24760 (53660) 53660..54070 + 411 WP_000210715.1 hypothetical protein -
EXA08_RS24765 (54130) 54130..54729 + 600 WP_000724374.1 type IV conjugative transfer system lipoprotein TraV -
EXA08_RS24770 (54740) 54740..57331 + 2592 WP_216264691.1 type IV secretion system protein TraC -
EXA08_RS24775 (57328) 57328..57792 + 465 WP_000206178.1 type-F conjugative transfer system protein TrbI -
EXA08_RS24780 (57792) 57792..58427 + 636 WP_000286241.1 type-F conjugative transfer system protein TraW -
EXA08_RS24785 (58424) 58424..59410 + 987 WP_001083236.1 conjugal transfer pilus assembly protein TraU -
EXA08_RS24790 (59421) 59421..59789 + 369 WP_000961327.1 hypothetical protein -
EXA08_RS24795 (59786) 59786..60400 + 615 WP_000832605.1 type-F conjugative transfer system pilin assembly protein TrbC -
EXA08_RS24800 (60397) 60397..62235 + 1839 WP_000833258.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
EXA08_RS24805 (62232) 62232..63011 + 780 WP_001202909.1 type-F conjugative transfer system pilin assembly protein TraF -
EXA08_RS24810 (63035) 63035..63637 + 603 WP_000906492.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
EXA08_RS24815 (63643) 63643..65004 + 1362 WP_001237467.1 conjugal transfer pilus assembly protein TraH -
EXA08_RS24820 (65006) 65006..67897 + 2892 WP_000963408.1 conjugal transfer mating-pair stabilization protein TraG -
EXA08_RS24825 (67907) 67907..68464 + 558 WP_001232425.1 hypothetical protein -
EXA08_RS24830 (68714) 68714..69376 + 663 WP_021018630.1 complement resistance protein TraT -
EXA08_RS24835 (69520) 69520..71751 + 2232 WP_000056170.1 type IV conjugative transfer system coupling protein TraD -
EXA08_RS24840 (71751) 71751..77051 + 5301 WP_087603298.1 Multifunctional conjugation protein TraI Relaxase
EXA08_RS24845 (77069) 77069..77635 + 567 WP_000469207.1 DUF2726 domain-containing protein -
EXA08_RS24850 (77632) 77632..78363 + 732 WP_001071488.1 type-F conjugative transfer system pilin acetylase TraX -
EXA08_RS24855 (78588) 78588..78770 - 183 WP_001393357.1 hypothetical protein -
EXA08_RS24860 (79277) 79277..79534 + 258 WP_000083823.1 replication regulatory protein RepA -
EXA08_RS25615 (79570) 79570..79806 - 237 WP_235588260.1 replication protein RepA -
EXA08_RS25620 (79797) 79797..79844 + 48 WP_235588261.1 hypothetical protein -
EXA08_RS24870 (79837) 79837..80694 + 858 WP_000130978.1 incFII family plasmid replication initiator RepA -
EXA08_RS24875 (81609) 81609..81878 + 270 WP_000079948.1 type II toxin-antitoxin system antitoxin YacA Antitoxin Detail
EXA08_RS24880 (81878) 81878..82156 + 279 WP_001384452.1 type II toxin-antitoxin system toxin YacB Toxin Detail
EXA08_RS24885 (82202) 82202..83050 + 849 WP_001057994.1 exonuclease domain-containing protein -
EXA08_RS24890 (83167) 83167..83649 + 483 WP_032182006.1 hypothetical protein -
EXA08_RS24895 (84184) 84184..84786 - 603 WP_000517689.1 ProQ/FINO family protein -
EXA08_RS24900 (85140) 85140..85661 + 522 Protein_95 hypothetical protein -
EXA08_RS24905 (85693) 85693..87264 - 1572 WP_000381379.1 IS66 family transposase ISCro1 Transposase
EXA08_RS24910 (87284) 87284..87631 - 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
EXA08_RS24915 (87631) 87631..88308 - 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
EXA08_RS24920 (88564) 88564..90444 + 1881 WP_032221836.1 colicin Ia central receptor-binding domain-containing protein -
EXA08_RS24925 (90466) 90466..90801 - 336 WP_001080730.1 colicin 1A immunity protein -
EXA08_RS24930 (90930) 90930..91277 + 348 WP_000142443.1 DUF6404 family protein -
EXA08_RS24935 (91295) 91295..91885 - 591 WP_045133249.1 hypothetical protein -
EXA08_RS24940 (91885) 91885..92142 - 258 WP_000371887.1 hypothetical protein -
EXA08_RS24945 (92410) 92410..93909 + 1500 WP_099588462.1 RES family NAD+ phosphorylase -
EXA08_RS24950 (93934) 93934..94797 - 864 WP_059278049.1 hypothetical protein -
EXA08_RS24955 (95132) 95132..96133 + 1002 WP_000138754.1 DUF4238 domain-containing protein -
EXA08_RS24960 (96317) 96317..96661 - 345 WP_000793772.1 hypothetical protein -
EXA08_RS24965 (97158) 97158..97415 - 258 WP_225379879.1 hypothetical protein -
EXA08_RS24970 (97456) 97456..98382 - 927 WP_001280608.1 hypothetical protein -
EXA08_RS24975 (98923) 98923..99273 + 351 WP_063101299.1 hypothetical protein -
EXA08_RS24980 (99343) 99343..99951 + 609 WP_016233127.1 hypothetical protein -
EXA08_RS24985 (100018) 100018..101180 + 1163 WP_085947598.1 IS3 family transposase ISEc17 Transposase
EXA08_RS24990 (101177) 101177..101323 - 147 WP_157774455.1 hypothetical protein -
EXA08_RS24995 (101811) 101811..103289 + 1479 WP_000927307.1 SulP family inorganic anion transporter -
EXA08_RS25000 (103308) 103308..104135 + 828 WP_001066651.1 universal stress protein -
EXA08_RS25005 (104195) 104195..104620 - 426 WP_000065762.1 glutaredoxin-dependent arsenate reductase -
EXA08_RS25010 (104633) 104633..105106 - 474 Protein_117 SLC13 family permease -
EXA08_RS25015 (105106) 105106..105399 + 294 Protein_118 arsenical resistance protein ArsH -
EXA08_RS25020 (105433) 105433..106836 - 1404 WP_000125671.1 ISNCY family transposase ISKpn21 Transposase
EXA08_RS25025 (107207) 107207..109144 + 1938 WP_000433597.1 NACHT domain-containing protein -
EXA08_RS25030 (109424) 109424..109690 + 267 WP_001356324.1 type II toxin-antitoxin system ParD family antitoxin -
EXA08_RS25035 (109677) 109677..109926 + 250 Protein_122 type II toxin-antitoxin system RelE/ParE family toxin -
EXA08_RS25040 (109948) 109948..110178 + 231 WP_139300220.1 serine/threonine protein kinase -
EXA08_RS25045 (110299) 110299..111039 + 741 WP_001066942.1 tyrosine-type recombinase/integrase -
EXA08_RS25050 (111324) 111324..112301 - 978 WP_000361612.1 RepB family plasmid replication initiator protein -
EXA08_RS25055 (113058) 113058..113753 + 696 Protein_126 hypothetical protein -
EXA08_RS25060 (113912) 113912..114652 - 741 WP_000933099.1 abortive infection family protein -
EXA08_RS25065 (114688) 114688..115269 - 582 WP_225890475.1 DUF2971 domain-containing protein -
EXA08_RS25625 (115285) 115285..115476 - 192 Protein_129 hypothetical protein -
EXA08_RS25070 (115473) 115473..116093 - 621 WP_001248529.1 hypothetical protein -
EXA08_RS25075 (116090) 116090..116773 - 684 WP_010891291.1 DNA-binding protein -
EXA08_RS25080 (117214) 117214..117528 + 315 WP_001302628.1 hypothetical protein -
EXA08_RS25085 (117590) 117590..118360 + 771 WP_001499400.1 hypothetical protein -
EXA08_RS25090 (118405) 118405..119187 + 783 WP_077635029.1 site-specific integrase -
EXA08_RS25095 (119368) 119368..120012 + 645 WP_001144036.1 ParA family protein -
EXA08_RS25100 (120099) 120099..120407 + 309 WP_000030201.1 hypothetical protein -
EXA08_RS25105 (120820) 120820..121800 + 981 WP_000688514.1 plasmid segregation protein ParM -
EXA08_RS25110 (121793) 121793..122209 + 417 WP_001278818.1 plasmid partitioning/stability family protein -
EXA08_RS25115 (122211) 122211..123485 - 1275 WP_000457490.1 Y-family DNA polymerase -
EXA08_RS25120 (123485) 123485..123922 - 438 WP_000109071.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
EXA08_RS25125 (123919) 123919..124167 - 249 WP_000618110.1 DinI-like family protein -
EXA08_RS25130 (124231) 124231..125451 - 1221 WP_000343765.1 ISL3 family transposase ISEc53 Transposase
EXA08_RS25135 (125470) 125470..125988 - 519 WP_000115885.1 hypothetical protein VF
EXA08_RS25140 (126478) 126478..127380 + 903 WP_001507408.1 DUF1281 domain-containing protein -
EXA08_RS25145 (127377) 127377..127688 + 312 WP_032260558.1 hypothetical protein -
EXA08_RS25150 (127764) 127764..128447 + 684 WP_000086148.1 DNA methylase -
EXA08_RS25155 (128448) 128448..128669 + 222 WP_001104867.1 hypothetical protein -
EXA08_RS25160 (128650) 128650..129117 + 468 WP_244407643.1 DUF1380 family protein -
EXA08_RS25165 (129162) 129162..129932 + 771 WP_001006235.1 hypothetical protein -
EXA08_RS25170 (130350) 130350..130775 + 426 WP_001198884.1 antirestriction protein -
EXA08_RS25175 (130822) 130822..131244 + 423 WP_000271739.1 DUF1380 family protein -
EXA08_RS25180 (131302) 131302..132873 - 1572 WP_000381379.1 IS66 family transposase ISCro1 Transposase
EXA08_RS25185 (132893) 132893..133240 - 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
EXA08_RS25190 (133240) 133240..133917 - 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
EXA08_RS25195 (133977) 133977..134500 - 524 Protein_155 IS1 family transposase -
EXA08_RS25200 (135027) 135027..135476 + 450 WP_000649995.1 hypothetical protein -
EXA08_RS25630 (135643) 135643..135795 + 153 Protein_157 phage integrase family protein -
EXA08_RS25210 (137254) 137254..137859 - 606 Protein_159 IS66 family transposase ISEc47 Transposase
EXA08_RS25215 (137890) 137890..138042 - 153 Protein_160 transposase -
EXA08_RS25225 (139302) 139302..139550 + 249 Protein_162 IS91 family transposase -
EXA08_RS25230 (139858) 139858..140574 + 717 WP_001460290.1 hypothetical protein VF
EXA08_RS25235 (140603) 140603..141112 + 510 WP_000768758.1 CFA/I fimbrial subunit B VF
EXA08_RS25240 (141122) 141122..141649 + 528 WP_000768759.1 CFA/I fimbrial subunit B VF
EXA08_RS25245 (141765) 141765..144332 + 2568 WP_077635032.1 hypothetical protein VF
EXA08_RS25250 (144336) 144336..145421 + 1086 WP_001033659.1 CFA/I fimbrial subunit E VF
EXA08_RS25255 (145582) 145582..146379 - 798 WP_001009833.1 CFA/I fimbrial subunit D VF
EXA08_RS25260 (146577) 146577..146771 + 195 WP_024168605.1 ANR family transcriptional regulator -
EXA08_RS25265 (148091) 148091..148954 + 864 WP_001460292.1 Right origin-binding protein VF
EXA08_RS25270 (149099) 149099..149206 - 108 Protein_171 IS110 family transposase ISEc21 Transposase
EXA08_RS25275 (149346) 149346..149558 - 213 Protein_172 Major pilu subunit operon regulatory protein PapB VF
EXA08_RS25280 (149678) 149678..150112 + 435 WP_001309734.1 IS66 family transposase ISEc43 Transposase
EXA08_RS25285 (150109) 150109..150309 + 201 Protein_174 IS66 family transposase ISEc47 Transposase
EXA08_RS25290 (150374) 150374..151536 + 1163 WP_085947598.1 IS3 family transposase ISEc17 Transposase
EXA08_RS25295 (151567) 151567..152295 - 729 Protein_176 IS91 family transposase ISEc37 Transposase
EXA08_RS25300 (152437) 152437..153650 + 1214 WP_216264687.1 IS3 family transposase IS629 Transposase
EXA08_RS25305 (153847) 153847..154491 + 645 WP_000633914.1 AAA family ATPase -
EXA08_RS25310 (154485) 154485..154760 + 276 WP_000239529.1 hypothetical protein -
EXA08_RS25315 (154898) 154898..155203 - 306 Protein_180 IS91 family transposase ISSod25 Transposase
EXA08_RS25320 (155294) 155294..156522 + 1229 WP_089541817.1 IS3 family transposase IS2 Transposase
EXA08_RS25325 (156534) 156534..157016 - 483 Protein_182 site-specific integrase -
EXA08_RS25330 (157018) 157018..157431 - 414 WP_000465050.1 hypothetical protein -
EXA08_RS25335 (158057) 158057..159076 + 1020 Protein_184 IS110 family transposase ISEc66 Transposase
EXA08_RS25340 (159357) 159357..159587 + 231 WP_024220872.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
EXA08_RS25345 (159584) 159584..160000 + 417 WP_001356337.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
EXA08_RS25350 (159967) 159967..160314 - 348 Protein_187 IS66 family transposase ISSfl3 Transposase
EXA08_RS25635 (160426) 160426..160560 + 135 Protein_188 IS66 family transposase ISSfl3 Transposase
EXA08_RS25360 (161868) 161868..162143 + 276 Protein_190 IS3 family transposase ISLad1 Transposase
EXA08_RS25365 (162152) 162152..162301 - 150 Protein_191 IS3 family transposase ISSfl10 Transposase
EXA08_RS25640 (162617) 162617..162826 - 210 WP_000129488.1 IS1 family transposase IS1X2 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance