MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 128911 bp
Accession: NZ_CP028484 Location: 1..128911 Organism: Escherichia coli strain E41-1 Replicon: plasmid p1
Accession: NZ_CP028484 Location: 1..128911 Organism: Escherichia coli strain E41-1 Replicon: plasmid p1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C2U19_RS26070 () | 87..512 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| C2U19_RS26075 () | 509..859 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| C2U19_RS26080 () | 890..2503 | + | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| C2U19_RS26085 () | 2581..2867 | + | 287 | Protein_3 | DUF2726 domain-containing protein | - |
| - () | 2834..2894 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 2834..2894 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 2834..2894 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 2834..2894 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| C2U19_RS26090 () | 2939..3073 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| C2U19_RS26095 () | 3370..3624 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| C2U19_RS28330 () | 3730..3864 | + | 135 | Protein_6 | protein CopA/IncA | - |
| C2U19_RS26105 () | 3861..3935 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| C2U19_RS26110 () | 3928..4785 | + | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| C2U19_RS26120 () | 5725..6378 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| C2U19_RS28140 () | 6471..6728 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| C2U19_RS26125 () | 6661..7062 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| C2U19_RS26135 () | 7347..8657 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| C2U19_RS26140 () | 8686..8784 | + | 99 | Protein_13 | IS1 family transposase | - |
| C2U19_RS26145 () | 8934..9794 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| C2U19_RS26150 () | 10155..10859 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| C2U19_RS26160 () | 10912..11418 | + | 507 | Protein_16 | transposase | - |
| C2U19_RS26165 () | 11427..12287 | + | 861 | WP_000493383.1 | EamA family transporter | - |
| C2U19_RS26170 () | 12319..13518 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| C2U19_RS26175 () | 13624..14250 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| C2U19_RS26180 () | 14282..14518 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| C2U19_RS26185 () | 14572..15408 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| C2U19_RS26190 () | 15408..16211 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| C2U19_RS26195 () | 16272..17087 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| C2U19_RS26210 () | 17395..17571 | - | 177 | Protein_24 | replication protein C | - |
| C2U19_RS26215 () | 17632..18336 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C2U19_RS26225 () | 18458..19363 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| C2U19_RS26230 () | 19360..20598 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| C2U19_RS26235 () | 20598..21182 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| C2U19_RS26250 () | 21675..22439 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| C2U19_RS28145 () | 22557..22622 | - | 66 | Protein_30 | EAL domain-containing protein | - |
| C2U19_RS26260 () | 22666..22971 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| C2U19_RS26265 () | 22982..24187 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| C2U19_RS26270 () | 24343..24546 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| C2U19_RS26280 () | 24674..25513 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| C2U19_RS26285 () | 25507..25854 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| C2U19_RS26290 () | 26060..26848 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| C2U19_RS26295 () | 26979..27452 | - | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| C2U19_RS26300 () | 27610..28359 | + | 750 | Protein_38 | IS91 family transposase ISAzo26 | Transposase |
| C2U19_RS26305 () | 28418..29122 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| C2U19_RS26315 () | 29272..29430 | + | 159 | WP_000449408.1 | DsbA family protein | - |
| C2U19_RS26320 () | 29420..29926 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| C2U19_RS26325 () | 30109..30924 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| C2U19_RS26335 () | 31271..33157 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| C2U19_RS26340 () | 33198..33725 | + | 528 | WP_000178050.1 | iron transporter | - |
| C2U19_RS26345 () | 33829..35208 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| C2U19_RS26350 () | 35211..36494 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| C2U19_RS26355 () | 36484..37614 | + | 1131 | WP_000729218.1 | ABC transporter permease | - |
| C2U19_RS26360 () | 37619..38314 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| C2U19_RS26365 () | 38301..38786 | + | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| C2U19_RS26370 () | 38811..39296 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| C2U19_RS26375 () | 39418..40051 | + | 634 | Protein_51 | histidine-type phosphatase | - |
| C2U19_RS26380 () | 40201..40374 | - | 174 | Protein_52 | IS5 family transposase ISKpn26 | Transposase |
| C2U19_RS26385 () | 40536..40703 | - | 168 | WP_001391954.1 | hypothetical protein | - |
| C2U19_RS26395 () | 41361..42100 | - | 740 | Protein_54 | IS3 family transposase IS629 | Transposase |
| C2U19_RS26400 () | 42126..42431 | + | 306 | Protein_55 | IS91 family transposase ISSbo1 | Transposase |
| C2U19_RS26410 () | 42954..44129 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| C2U19_RS26415 () | 44198..46459 | - | 2262 | WP_110204511.1 | TonB-dependent receptor | - |
| C2U19_RS26420 () | 46628..47404 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| C2U19_RS26425 () | 47412..48287 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| C2U19_RS26430 () | 48619..49166 | - | 548 | Protein_60 | primase alpha helix C-terminal domain-containing protein | - |
| C2U19_RS26455 () | 50738..51073 | - | 336 | WP_001545741.1 | colicin 1A immunity protein | - |
| C2U19_RS26465 () | 51202..51548 | + | 347 | Protein_62 | hypothetical protein | - |
| C2U19_RS26470 () | 51568..52077 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| C2U19_RS26475 () | 52074..52334 | - | 261 | WP_000371882.1 | hypothetical protein | - |
| C2U19_RS26480 () | 52436..53175 | + | 740 | Protein_65 | IS3 family transposase IS629 | Transposase |
| C2U19_RS26490 () | 53848..55356 | + | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| C2U19_RS26495 () | 55446..55829 | + | 384 | Protein_67 | IS3 family transposase IS629 | Transposase |
| C2U19_RS26500 () | 55858..56262 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| C2U19_RS26505 () | 56259..56606 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| C2U19_RS26510 () | 56655..57600 | + | 946 | Protein_70 | IS66 family transposase ISEc8 | Transposase |
| C2U19_RS26515 () | 57686..58708 | + | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| C2U19_RS26520 () | 58705..59487 | + | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| C2U19_RS26525 () | 59555..60163 | + | 609 | Protein_73 | IS66 family transposase ISEc22 | Transposase |
| C2U19_RS26530 () | 60226..61017 | - | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| C2U19_RS26535 () | 61024..62994 | - | 1971 | WP_001298664.1 | Hemin receptor | VF |
| C2U19_RS26540 () | 63276..63712 | + | 437 | Protein_76 | IS3 family transposase IS2 | Transposase |
| C2U19_RS26545 () | 64237..64509 | + | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| C2U19_RS26550 () | 64955..65130 | + | 176 | Protein_78 | IS3 family transposase | - |
| C2U19_RS26555 () | 65356..66525 | - | 1170 | WP_110204512.1 | hypothetical protein | - |
| C2U19_RS26560 () | 66892..67080 | + | 189 | WP_110204513.1 | serine/threonine protein kinase | - |
| C2U19_RS26565 () | 67201..67941 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| C2U19_RS26570 () | 68226..69203 | - | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| C2U19_RS26580 () | 69989..70720 | + | 732 | WP_001617898.1 | hypothetical protein | - |
| C2U19_RS26585 () | 71089..71337 | - | 249 | Protein_84 | abortive infection family protein | - |
| C2U19_RS26595 () | 71395..72092 | + | 698 | Protein_85 | IS1 family transposase IS1R | Transposase |
| C2U19_RS26600 () | 72108..72437 | + | 330 | Protein_86 | TOBE domain-containing protein | - |
| C2U19_RS26605 () | 72546..73478 | - | 933 | WP_110204514.1 | homocysteine S-methyltransferase | - |
| C2U19_RS26610 () | 73465..74868 | - | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| C2U19_RS26620 () | 75112..76092 | + | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| C2U19_RS26625 () | 76320..76637 | + | 318 | WP_001513659.1 | hypothetical protein | - |
| C2U19_RS26630 () | 76587..77000 | - | 414 | Protein_91 | IS3 family transposase ISLad1 | Transposase |
| C2U19_RS26635 () | 76924..77283 | - | 360 | WP_001513660.1 | hypothetical protein | - |
| C2U19_RS26640 () | 77311..77490 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| C2U19_RS26645 () | 77495..77875 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| C2U19_RS26650 () | 77875..78096 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| C2U19_RS26655 () | 78279..79835 | + | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| C2U19_RS26660 () | 79832..81115 | + | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| C2U19_RS26665 () | 81237..82553 | + | 1317 | Protein_98 | HsdR family type I site-specific deoxyribonuclease | - |
| C2U19_RS26675 () | 82605..83302 | + | 698 | Protein_99 | IS1 family transposase IS1G | Transposase |
| C2U19_RS26680 () | 83439..84371 | - | 933 | WP_000991832.1 | hypothetical protein | - |
| C2U19_RS26700 () | 85802..86623 | - | 822 | WP_110204516.1 | nucleotidyltransferase | - |
| C2U19_RS26705 () | 87331..87549 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| C2U19_RS26710 () | 87551..87856 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| C2U19_RS26715 () | 87857..88663 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| C2U19_RS26720 () | 89437..90192 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| C2U19_RS26725 () | 90780..91946 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| C2U19_RS26730 () | 91946..92917 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| C2U19_RS26745 () | 93784..94686 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| C2U19_RS26750 () | 94690..94994 | + | 305 | Protein_110 | hypothetical protein | - |
| C2U19_RS26755 () | 95071..95754 | + | 684 | WP_000086185.1 | DNA methylase | - |
| C2U19_RS26760 () | 95755..95976 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| C2U19_RS26765 () | 95990..96424 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| C2U19_RS28150 () | 96475..97251 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| C2U19_RS26780 () | 97792..98094 | + | 303 | WP_001436678.1 | antirestriction protein | - |
| C2U19_RS26785 () | 98141..98563 | + | 423 | WP_000271741.1 | DUF1380 family protein | - |
| C2U19_RS26790 () | 98560..98751 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| C2U19_RS26805 () | 99786..100016 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| C2U19_RS26810 () | 100068..101429 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| C2U19_RS26815 () | 101477..102040 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| C2U19_RS26820 () | 102066..102314 | + | 249 | WP_001553845.1 | hypothetical protein | - |
| C2U19_RS26835 () | 102957..103496 | + | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| C2U19_RS26840 () | 103559..103792 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| C2U19_RS26845 () | 103858..105816 | + | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| C2U19_RS26850 () | 105871..106305 | + | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| C2U19_RS26855 () | 106302..107021 | + | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| - () | 107033..107219 | + | 187 | NuclAT_0 | - | - |
| - () | 107033..107219 | + | 187 | NuclAT_0 | - | - |
| - () | 107033..107219 | + | 187 | NuclAT_0 | - | - |
| - () | 107033..107219 | + | 187 | NuclAT_0 | - | - |
| C2U19_RS26860 () | 107267..108636 | + | 1370 | WP_085947770.1 | IS3 family transposase IS150 | Transposase |
| - () | 108663..108703 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 108663..108703 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 108663..108703 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 108663..108703 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| C2U19_RS26865 () | 108747..108905 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| C2U19_RS26885 () | 109826..110134 | + | 309 | WP_110204518.1 | hypothetical protein | - |
| C2U19_RS26890 () | 110163..110860 | + | 698 | Protein_130 | IS1 family transposase IS1G | Transposase |
| C2U19_RS26895 () | 110908..111228 | + | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| C2U19_RS26900 () | 111355..111639 | + | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| C2U19_RS26905 () | 111626..112171 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| C2U19_RS26910 () | 112101..112448 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| C2U19_RS26915 () | 112396..112821 | + | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| C2U19_RS26920 () | 112808..114181 | + | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| C2U19_RS26925 () | 114178..116997 | + | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| C2U19_RS26930 () | 117016..117513 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| C2U19_RS26935 () | 117545..118276 | + | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| C2U19_RS26940 () | 118479..119258 | + | 780 | WP_000199914.1 | hypothetical protein | - |
| C2U19_RS26945 () | 119255..121444 | + | 2190 | WP_024946705.1 | type IV conjugative transfer system coupling protein TraD | - |
| C2U19_RS26950 () | 121444..126714 | + | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| C2U19_RS26955 () | 126734..127480 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| C2U19_RS26960 () | 127535..128095 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| C2U19_RS26965 () | 128226..128438 | + | 213 | WP_013023861.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|