MGE detailed information
MGE type: Mobilizable plasmid MGE length: 74904 bp
Accession: NZ_CP027438 Location: 1..74904 Organism: Escherichia coli strain 2012C-4221 Replicon: plasmid unnamed1
Accession: NZ_CP027438 Location: 1..74904 Organism: Escherichia coli strain 2012C-4221 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6W65_RS25440 () | 219..1463 | + | 1245 | WP_158709090.1 | hypothetical protein | VF |
| C6W65_RS25445 () | 1466..1993 | + | 528 | WP_106906969.1 | hypothetical protein | - |
| C6W65_RS25450 () | 2000..3580 | + | 1581 | WP_106906970.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| C6W65_RS25455 () | 3587..4651 | + | 1065 | WP_106906971.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| C6W65_RS25460 () | 4658..5638 | + | 981 | WP_199851541.1 | ComG operon protein 1 | VF |
| C6W65_RS25465 () | 5628..6374 | + | 747 | WP_106906973.1 | Leader peptidase PppA | VF |
| C6W65_RS25470 () | 6362..6775 | + | 414 | WP_106906974.1 | hypothetical protein | VF |
| C6W65_RS25475 () | 7001..7431 | + | 431 | Protein_8 | hypothetical protein | - |
| C6W65_RS25480 () | 7440..8030 | + | 591 | WP_106906975.1 | hypothetical protein | - |
| C6W65_RS25485 () | 8020..8619 | + | 600 | WP_106906976.1 | hypothetical protein | - |
| C6W65_RS25490 () | 8641..9060 | + | 420 | WP_106906977.1 | hypothetical protein | - |
| C6W65_RS27055 () | 9106..9735 | + | 630 | WP_199851542.1 | Major structural subunit of bundle-forming pilus | VF |
| C6W65_RS25500 () | 9846..10545 | - | 700 | Protein_13 | IS3 family transposase | - |
| C6W65_RS25505 () | 10986..11774 | - | 789 | WP_106906978.1 | Virulence regulon transcriptional activator VirF | VF |
| C6W65_RS25510 () | 12129..13349 | + | 1221 | WP_106906979.1 | hypothetical protein | - |
| C6W65_RS26950 () | 13673..13932 | + | 260 | Protein_16 | IS3 family transposase | - |
| C6W65_RS25515 () | 13958..14653 | - | 696 | Protein_17 | helix-turn-helix domain-containing protein | - |
| C6W65_RS25525 () | 14928..16117 | + | 1190 | Protein_18 | IS3 family transposase IS2 | Transposase |
| C6W65_RS25530 () | 16669..17796 | + | 1128 | WP_106906980.1 | ABC transporter permease | - |
| C6W65_RS25535 () | 17793..19004 | + | 1212 | WP_106906981.1 | TolC family protein | - |
| C6W65_RS25540 () | 18928..19740 | + | 813 | WP_106906982.1 | hypothetical protein | - |
| C6W65_RS25545 () | 19733..20362 | + | 630 | WP_106906983.1 | ABC transporter ATP-binding protein | - |
| C6W65_RS27060 () | 20372..20618 | + | 247 | Protein_23 | IS3 family transposase | - |
| C6W65_RS25555 () | 20700..20884 | - | 185 | Protein_24 | integrase core domain-containing protein | - |
| C6W65_RS25565 () | 20985..22007 | + | 1023 | WP_106906984.1 | IS21 family transposase IS100kyp | Transposase |
| C6W65_RS25570 () | 22004..22786 | + | 783 | WP_001317493.1 | IS21 family transposase IS100kyp | Transposase |
| C6W65_RS25575 () | 22853..23101 | + | 249 | Protein_27 | 3-oxo-glucose-6-phosphate:glutamate aminotransferase | VF |
| C6W65_RS25580 () | 23103..23915 | + | 813 | Protein_28 | monooxygenase | - |
| C6W65_RS25585 () | 23947..24399 | - | 453 | WP_106906985.1 | N-acetyltransferase | - |
| C6W65_RS25590 () | 24727..24987 | + | 261 | WP_089636705.1 | hypothetical protein | - |
| C6W65_RS25595 () | 24984..25574 | + | 591 | WP_106906987.1 | hypothetical protein | - |
| C6W65_RS25600 () | 25594..25941 | - | 348 | WP_106906989.1 | hypothetical protein | - |
| C6W65_RS25610 () | 26070..26405 | + | 336 | Protein_33 | colicin E1 immunity protein | - |
| C6W65_RS25615 () | 26427..28306 | - | 1880 | Protein_34 | colicin | - |
| C6W65_RS25625 () | 29159..29563 | - | 405 | WP_000154256.1 | DUF2251 domain-containing protein | - |
| C6W65_RS25630 () | 29733..30020 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| C6W65_RS25635 () | 30017..30268 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| C6W65_RS25650 () | 31231..32088 | - | 858 | WP_158709091.1 | incFII family plasmid replication initiator RepA | - |
| C6W65_RS25655 () | 32081..32155 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| C6W65_RS25665 () | 32386..32643 | - | 258 | WP_106906995.1 | replication regulatory protein RepA | - |
| C6W65_RS25670 () | 32927..33076 | - | 150 | WP_106906997.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 33121..33180 | + | 60 | NuclAT_0 | - | Antitoxin Detail |
| - () | 33121..33180 | + | 60 | NuclAT_0 | - | Antitoxin Detail |
| - () | 33121..33180 | + | 60 | NuclAT_0 | - | Antitoxin Detail |
| - () | 33121..33180 | + | 60 | NuclAT_0 | - | Antitoxin Detail |
| C6W65_RS25680 () | 33346..35490 | - | 2145 | WP_106907000.1 | peptidase domain-containing ABC transporter | - |
| C6W65_RS25685 () | 35487..36770 | - | 1284 | WP_106907002.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| C6W65_RS25690 () | 37149..37724 | - | 576 | WP_106907004.1 | hypothetical protein | - |
| C6W65_RS25695 () | 38213..38511 | + | 299 | Protein_45 | IS3 family transposase ISKpn37 | Transposase |
| C6W65_RS26955 () | 38510..38632 | - | 123 | Protein_46 | endonuclease | - |
| C6W65_RS25700 () | 38878..39090 | - | 213 | WP_106907006.1 | hypothetical protein | - |
| C6W65_RS25705 () | 39226..39792 | - | 567 | WP_106907008.1 | fertility inhibition protein FinO | - |
| C6W65_RS25710 () | 39847..40328 | - | 482 | Protein_49 | type-F conjugative transfer system pilin acetylase TraX | - |
| C6W65_RS25715 () | 40370..41583 | + | 1214 | WP_106907009.1 | IS3 family transposase ISEc31 | Transposase |
| C6W65_RS26960 () | 41576..41728 | - | 153 | WP_158709092.1 | conjugal transfer protein | - |
| C6W65_RS25720 () | 41728..42456 | - | 729 | WP_158709093.1 | type-F conjugative transfer system secretin TraK | - |
| C6W65_RS25725 () | 42443..43009 | - | 567 | WP_106907011.1 | type IV conjugative transfer system protein TraE | - |
| C6W65_RS25730 () | 43031..43342 | - | 312 | WP_000012112.1 | type IV conjugative transfer system protein TraL | - |
| C6W65_RS25735 () | 43357..43722 | - | 366 | WP_033552937.1 | type IV conjugative transfer system pilin TraA | - |
| C6W65_RS25740 () | 43774..43983 | - | 210 | WP_106907013.1 | conjugal transfer relaxosome protein TraY | - |
| C6W65_RS25750 () | 44944..45327 | - | 384 | WP_106907015.1 | relaxosome protein TraM | - |
| C6W65_RS25755 () | 45660..46250 | + | 591 | WP_199851540.1 | hypothetical protein | VF |
| C6W65_RS25760 () | 46547..47367 | - | 821 | Protein_59 | DUF932 domain-containing protein | - |
| C6W65_RS25765 () | 47485..47772 | - | 288 | WP_104750695.1 | hypothetical protein | - |
| C6W65_RS27065 () | 47797..48003 | - | 207 | WP_031570430.1 | hypothetical protein | - |
| C6W65_RS27070 () | 48073..48390 | + | 318 | Protein_62 | hypothetical protein | - |
| C6W65_RS25790 () | 48562..48753 | - | 192 | WP_106907018.1 | hypothetical protein | - |
| C6W65_RS25795 () | 48750..49172 | - | 423 | WP_106907019.1 | DUF1380 family protein | - |
| C6W65_RS25800 () | 49219..49521 | - | 303 | WP_130559398.1 | antirestriction protein | - |
| C6W65_RS25815 () | 50112..51014 | - | 903 | WP_106907041.1 | DUF1281 domain-containing protein | - |
| C6W65_RS25825 () | 51432..51554 | + | 123 | Protein_67 | DinI family protein | - |
| C6W65_RS25830 () | 51695..52087 | - | 393 | WP_000272016.1 | plasmid partitioning/stability family protein | - |
| C6W65_RS25835 () | 52091..53065 | - | 975 | WP_097469860.1 | StbA family protein | - |
| C6W65_RS25840 () | 53304..53678 | - | 375 | WP_106907023.1 | hypothetical protein | - |
| C6W65_RS25845 () | 53678..54310 | - | 633 | WP_000312330.1 | ParA family protein | - |
| C6W65_RS25855 () | 55066..55821 | - | 756 | WP_000807692.1 | replication initiation protein RepE | - |
| C6W65_RS25860 () | 56324..56594 | - | 271 | Protein_73 | tyrosine-type recombinase/integrase | - |
| C6W65_RS25865 () | 56595..56900 | - | 306 | WP_106907027.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| C6W65_RS25870 () | 56902..57120 | - | 219 | WP_000813639.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| C6W65_RS25875 () | 57513..57884 | - | 372 | Protein_76 | Tn3 family transposase TnpA_ISXc4 | Transposase |
| C6W65_RS25880 () | 58004..58378 | - | 375 | Protein_77 | transposase zinc-binding domain-containing protein | - |
| C6W65_RS25885 () | 58333..58581 | - | 249 | WP_158709094.1 | hypothetical protein | - |
| C6W65_RS27075 () | 58727..58983 | + | 257 | Protein_79 | IS3 family transposase | - |
| C6W65_RS25895 () | 59234..59941 | - | 708 | WP_106907045.1 | AraC family transcriptional regulator | - |
| C6W65_RS25900 () | 60978..61385 | + | 408 | WP_158709095.1 | hypothetical protein | - |
| C6W65_RS25905 () | 61536..62194 | + | 659 | Protein_82 | IS4 family transposase IS421 | Transposase |
| C6W65_RS26965 () | 62458..62823 | - | 366 | WP_158709096.1 | hypothetical protein | - |
| C6W65_RS25910 () | 63524..64224 | + | 701 | Protein_84 | transposase | - |
| C6W65_RS25915 () | 64343..64429 | + | 87 | Protein_85 | IS200/IS605 family transposase | - |
| C6W65_RS25920 () | 64492..65642 | + | 1151 | WP_106905993.1 | IS3 family transposase ISEc16 | Transposase |
| C6W65_RS25925 () | 65686..66024 | + | 339 | Protein_87 | IS200/IS605 family transposase | - |
| C6W65_RS25930 () | 66091..66346 | + | 256 | Protein_88 | DDE-type integrase/transposase/recombinase | - |
| C6W65_RS25935 () | 66413..67196 | - | 784 | Protein_89 | IS21 family transposase IS100kyp | Transposase |
| C6W65_RS25940 () | 67193..68215 | - | 1023 | WP_106906984.1 | IS21 family transposase IS100kyp | Transposase |
| C6W65_RS25945 () | 68229..68372 | - | 144 | WP_158709097.1 | hypothetical protein | - |
| C6W65_RS25950 () | 69368..70537 | - | 1170 | Protein_92 | IS3 family transposase | - |
| C6W65_RS25960 () | 72333..72923 | + | 591 | WP_106907048.1 | Major structural subunit of bundle-forming pilus | VF |
| C6W65_RS25965 () | 72966..73430 | + | 465 | WP_106907033.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|