MGE detailed information
MGE type: Conjugative plasmid MGE length: 111779 bp
Accession: NZ_CP024718 Location: 1..111779 Organism: Escherichia coli strain LS4 Replicon: plasmid p1LS4
Accession: NZ_CP024718 Location: 1..111779 Organism: Escherichia coli strain LS4 Replicon: plasmid p1LS4
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CUB99_RS27000 () | 66..287 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| CUB99_RS27005 () | 288..971 | - | 684 | WP_000086185.1 | DNA methylase | - |
| CUB99_RS28265 () | 1048..1352 | - | 305 | Protein_3 | hypothetical protein | - |
| CUB99_RS27015 () | 1531..1965 | + | 435 | WP_001309734.1 | IS66 family transposase ISEc43 | Transposase |
| CUB99_RS27020 () | 1962..2312 | + | 351 | WP_000624688.1 | IS66 family transposase ISEc47 | Transposase |
| CUB99_RS27025 () | 2343..3956 | + | 1614 | WP_000080172.1 | IS66 family transposase ISEc43 | Transposase |
| CUB99_RS27030 () | 3983..4807 | - | 825 | WP_099996264.1 | DUF1281 domain-containing protein | - |
| CUB99_RS27045 () | 5674..6645 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| CUB99_RS27050 () | 6645..7811 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| CUB99_RS27055 () | 8399..9154 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| CUB99_RS27060 () | 9928..10734 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| CUB99_RS27065 () | 10735..11040 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| CUB99_RS27070 () | 11042..11260 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| CUB99_RS27075 () | 11806..12318 | + | 513 | WP_000151784.1 | hypothetical protein | - |
| CUB99_RS27080 () | 12352..13485 | - | 1134 | WP_000545986.1 | DUF3800 domain-containing protein | - |
| CUB99_RS27085 () | 13652..14425 | - | 774 | WP_000905949.1 | hypothetical protein | - |
| CUB99_RS27090 () | 14438..14938 | - | 501 | WP_000528932.1 | hypothetical protein | - |
| CUB99_RS27095 () | 15203..15433 | + | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| CUB99_RS27105 () | 15515..16212 | + | 698 | Protein_19 | IS1 family transposase IS1A | Transposase |
| CUB99_RS27110 () | 16392..16905 | - | 514 | Protein_20 | DUF4113 domain-containing protein | - |
| CUB99_RS28270 () | 16966..17070 | - | 105 | Protein_21 | AAA family ATPase | - |
| CUB99_RS27120 () | 17072..17395 | - | 324 | Protein_22 | IS21 family transposase IS21 | Transposase |
| CUB99_RS27130 () | 18141..19118 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| CUB99_RS27135 () | 19403..20143 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| CUB99_RS27140 () | 20264..20446 | - | 183 | WP_042344623.1 | hypothetical protein | - |
| CUB99_RS27150 () | 20789..21096 | - | 308 | Protein_26 | type II toxin-antitoxin system ParD family antitoxin | - |
| CUB99_RS27160 () | 21589..22758 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| CUB99_RS27165 () | 22791..22919 | + | 129 | Protein_28 | IS481 family transposase | - |
| CUB99_RS27170 () | 22954..23247 | - | 294 | WP_001105060.1 | hypothetical protein | - |
| CUB99_RS27175 () | 23353..23628 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| CUB99_RS27180 () | 23628..23912 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| CUB99_RS27185 () | 24517..25269 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| CUB99_RS27190 () | 25315..26280 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| CUB99_RS27195 () | 26313..26693 | - | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| CUB99_RS27200 () | 26718..27608 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| CUB99_RS27210 () | 28009..28449 | + | 441 | Protein_36 | zinc-binding dehydrogenase | - |
| CUB99_RS27215 () | 28580..29458 | + | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| CUB99_RS27220 () | 29448..30335 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| CUB99_RS27225 () | 30346..31170 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| CUB99_RS27230 () | 31176..32249 | + | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| CUB99_RS27235 () | 32242..33552 | + | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| CUB99_RS27240 () | 33611..33919 | - | 309 | Protein_42 | IS4 family transposase ISEc13 | Transposase |
| CUB99_RS27245 () | 33996..34229 | - | 234 | Protein_43 | Tn3 family transposase ISPsy39 | Transposase |
| CUB99_RS27250 () | 34251..35447 | - | 1197 | Protein_44 | IS3 family transposase | - |
| CUB99_RS27255 () | 35472..36176 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| CUB99_RS27260 () | 36234..36764 | - | 531 | Protein_46 | histidine-type phosphatase | - |
| CUB99_RS27265 () | 36886..37371 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| CUB99_RS27270 () | 37396..37881 | - | 486 | WP_001267177.1 | TlpA family protein disulfide reductase | - |
| CUB99_RS27275 () | 37868..38563 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| CUB99_RS27280 () | 38568..39698 | - | 1131 | WP_000729220.1 | ABC transporter permease | - |
| CUB99_RS27285 () | 39688..40971 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| CUB99_RS27290 () | 40974..42353 | - | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| CUB99_RS27295 () | 42457..42984 | - | 528 | WP_000178050.1 | iron transporter | - |
| CUB99_RS27300 () | 43025..44911 | - | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| CUB99_RS27310 () | 45258..46073 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| CUB99_RS27315 () | 46299..47003 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CUB99_RS27325 () | 47056..51672 | + | 4617 | Protein_57 | Multifunctional conjugation protein TraI | Relaxase |
| CUB99_RS27330 () | 51692..52438 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| CUB99_RS27335 () | 52497..53357 | + | 861 | WP_000704528.1 | putative protein YcjY | VF |
| CUB99_RS27340 () | 53460..54020 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| CUB99_RS27345 () | 54149..54361 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| CUB99_RS27350 () | 54606..55067 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| CUB99_RS27355 () | 55113..55322 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| CUB99_RS27360 () | 55360..55950 | + | 591 | WP_000766805.1 | DUF2726 domain-containing protein | - |
| CUB99_RS27365 () | 56190..56450 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| CUB99_RS27375 () | 56675..56749 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| CUB99_RS27380 () | 56742..57599 | + | 858 | WP_000130647.1 | incFII family plasmid replication initiator RepA | - |
| CUB99_RS27390 () | 58625..59485 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| CUB99_RS27395 () | 59668..60225 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| CUB99_RS27400 () | 60389..60598 | + | 210 | Protein_70 | Tn3 family transposase TnpA_Tn3 | Transposase |
| CUB99_RS27405 () | 60652..61356 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CUB99_RS27410 () | 61455..62528 | + | 1074 | Protein_72 | Methyl-accepting chemotaxis protein McpQ | VF |
| CUB99_RS27415 () | 62821..63282 | - | 462 | WP_000978817.1 | thermonuclease family protein | - |
| CUB99_RS27420 () | 63476..64180 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CUB99_RS28275 () | 64221..64400 | - | 180 | Protein_75 | recombinase family protein | - |
| CUB99_RS28070 () | 64526..64876 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| CUB99_RS27435 () | 65079..66092 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| CUB99_RS27440 () | 66250..66723 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| CUB99_RS27445 () | 66854..67642 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| CUB99_RS27450 () | 67848..68195 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| CUB99_RS27455 () | 68189..69028 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| CUB99_RS27465 () | 69156..69656 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| CUB99_RS27470 () | 69832..70614 | - | 783 | WP_001163403.1 | IS21 family transposase IS1326 | Transposase |
| CUB99_RS27475 () | 70604..72127 | - | 1524 | WP_001324342.1 | IS21 family transposase IS1326 | Transposase |
| CUB99_RS27480 () | 72250..73794 | + | 1545 | WP_000287615.1 | IS3 family transposase IS1353 | Transposase |
| CUB99_RS27485 () | 73845..74705 | - | 861 | WP_000344784.1 | TniB family NTP-binding protein | - |
| CUB99_RS27490 () | 74708..76387 | - | 1680 | WP_000179844.1 | DDE-type integrase/transposase/recombinase | - |
| CUB99_RS27500 () | 76462..77130 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| CUB99_RS27505 () | 77166..77402 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| CUB99_RS27510 () | 77399..77761 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| CUB99_RS27515 () | 77779..79473 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| CUB99_RS27520 () | 79525..79947 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| CUB99_RS27525 () | 79983..80258 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| CUB99_RS27530 () | 80272..80622 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| CUB99_RS27535 () | 80694..81128 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| CUB99_RS27540 () | 81235..81932 | - | 698 | Protein_96 | IS1 family transposase IS1R | Transposase |
| CUB99_RS27550 () | 82181..82582 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| CUB99_RS28075 () | 82515..82772 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| CUB99_RS27555 () | 82865..83518 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| CUB99_RS27560 () | 83617..86418 | - | 2802 | Protein_100 | Tn3 family transposase TnpA_Tn3 | Transposase |
| CUB99_RS27565 () | 86483..87187 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| CUB99_RS27575 () | 87256..89883 | - | 2628 | WP_001064239.1 | type IV secretion system protein TraC | - |
| CUB99_RS27580 () | 90043..90264 | - | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| CUB99_RS27585 () | 90399..90914 | - | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| CUB99_RS27590 () | 90911..91162 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| CUB99_RS27595 () | 91155..91508 | - | 354 | WP_071528018.1 | conjugal transfer protein TrbD | - |
| CUB99_RS27600 () | 91462..92046 | - | 585 | WP_000002795.1 | conjugal transfer protein TraP | - |
| CUB99_RS27605 () | 92036..93463 | - | 1428 | WP_000146638.1 | conjugal transfer protein TraB | - |
| CUB99_RS27610 () | 93463..94167 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| CUB99_RS27615 () | 94178..94744 | - | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| CUB99_RS27620 () | 94766..95077 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| CUB99_RS27625 () | 95082..95444 | - | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| CUB99_RS27630 () | 95478..95705 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| CUB99_RS27635 () | 95799..96485 | - | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| CUB99_RS27640 () | 96679..97062 | - | 384 | WP_001151564.1 | relaxosome protein TraM | - |
| CUB99_RS27645 () | 97348..97995 | + | 648 | WP_000614282.1 | hypothetical protein | VF |
| CUB99_RS27650 () | 98292..99113 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| CUB99_RS27655 () | 99234..99521 | - | 288 | WP_099996262.1 | hypothetical protein | - |
| CUB99_RS27680 () | 100440..100598 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 100642..100866 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 100642..100866 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 100642..100866 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 100642..100866 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| CUB99_RS28080 () | 100678..100866 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| CUB99_RS27685 () | 100878..101597 | - | 720 | WP_001276234.1 | plasmid SOS inhibition protein A | - |
| CUB99_RS27690 () | 101594..102028 | - | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| CUB99_RS27695 () | 102083..104041 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| CUB99_RS27700 () | 104100..104333 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| CUB99_RS27705 () | 104389..104916 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| CUB99_RS27740 () | 105780..106343 | - | 564 | WP_012783964.1 | class I SAM-dependent methyltransferase | - |
| CUB99_RS27745 () | 106390..107751 | - | 1362 | WP_000170728.1 | DUF3560 domain-containing protein | - |
| CUB99_RS27750 () | 107803..108033 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| CUB99_RS27765 () | 109068..109259 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| CUB99_RS27770 () | 109256..109678 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| CUB99_RS27775 () | 109725..110026 | - | 302 | Protein_131 | antirestriction protein | - |
| CUB99_RS27785 () | 110588..111346 | - | 759 | Protein_132 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|